Stefan Kubicek

Stefan Kubicek

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Stefan Kubicek

Stefan Kubicek

Publications by authors named "Stefan Kubicek"

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Mapping the perturbome network of cellular perturbations.

Nat Commun 2019 11 13;10(1):5140. Epub 2019 Nov 13.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, A-1090, Vienna, Austria.

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http://dx.doi.org/10.1038/s41467-019-13058-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853941PMC
November 2019

A Domino 10-Step Total Synthesis of FR252921 and Its Analogues, Complex Macrocyclic Immunosuppressants.

J Am Chem Soc 2019 Sep 22;141(35):13772-13777. Epub 2019 Aug 22.

Institute of Organic Chemistry , University of Vienna , Währinger Strasse 38 , 1090 Vienna , Austria.

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http://dx.doi.org/10.1021/jacs.9b07185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837725PMC
September 2019

Mapping the Human Kinome in Response to DNA Damage.

Cell Rep 2019 01;26(3):555-563.e6

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.12.087DOI Listing
January 2019

Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH.

Mol Cell 2017 Nov;68(4):797-807.e7

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.10.021DOI Listing
November 2017

A histone-mimicking interdomain linker in a multidomain protein modulates multivalent histone binding.

J Biol Chem 2017 10 1;292(43):17643-17657. Epub 2017 Sep 1.

From the Department of Biochemistry, Max F. Perutz Laboratories, University of Vienna, Campus Vienna Biocenter, Dr. Bohr-Gasse 9, 1030 Vienna, Austria,

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http://www.jbc.org/lookup/doi/10.1074/jbc.M117.801464
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http://dx.doi.org/10.1074/jbc.M117.801464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663869PMC
October 2017

FASIL-MS: An Integrated Proteomic and Bioinformatic Workflow To Universally Quantitate In Vivo-Acetylated Positional Isomers.

J Proteome Res 2016 08 5;15(8):2579-94. Epub 2016 Jul 5.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences , A-1090 Vienna, Austria.

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http://dx.doi.org/10.1021/acs.jproteome.6b00130DOI Listing
August 2016

Pharmacological treats for SUMO addicts.

Pharmacol Res 2016 05 24;107:390-397. Epub 2016 Jan 24.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, 1090 Vienna, Austria; Christian Doppler Laboratory for Chemical Epigenetics and Antiinfectives, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2016.01.004DOI Listing
May 2016

Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.

EMBO Rep 2016 Feb 21;17(2):178-87. Epub 2015 Dec 21.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria Christian Doppler Laboratory for Chemical Epigenetics and Antiinfectives, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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http://dx.doi.org/10.15252/embr.201540946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784001PMC
February 2016

Stimulating translational research: several European life science institutions put their heads together.

Trends Mol Med 2015 Sep 5;21(9):525-7. Epub 2015 Aug 5.

EU-Life Translational Working Group; Centre for Genomic Regulation (CRG), Dr Aiguader 88, 08003 Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.molmed.2015.07.002DOI Listing
September 2015

Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1.

Cell Rep 2015 Feb 19;10(7):1082-95. Epub 2015 Feb 19.

Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, 1090 Vienna, Austria; Department of Pediatrics, Medical University of Vienna, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.01.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542316PMC
February 2015

Exploiting epigenetic vulnerabilities for cancer therapeutics.

Trends Pharmacol Sci 2014 Mar 12;35(3):136-45. Epub 2014 Feb 12.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2014.01.001DOI Listing
March 2014

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B.

Mol Cancer Ther 2011 Oct 18;10(10):1846-56. Epub 2011 Jul 18.

Ce-M-M-Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090 Vienna, Austria.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0100DOI Listing
October 2011

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres.

Nat Struct Mol Biol 2010 Oct 3;17(10):1218-25. Epub 2010 Oct 3.

The Salk Institute for Biological Studies, Molecular and Cellular Biology Department, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nsmb.1897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951278PMC
October 2010

Small-molecule inducers of insulin expression in pancreatic alpha-cells.

Proc Natl Acad Sci U S A 2010 Aug 9;107(34):15099-104. Epub 2010 Aug 9.

Howard Hughes Medical Institute, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142.

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http://dx.doi.org/10.1073/pnas.1010018107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930573PMC
August 2010

Repression of p53 activity by Smyd2-mediated methylation.

Nature 2006 Nov 15;444(7119):629-32. Epub 2006 Nov 15.

Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania 19104, USA.

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http://www.nature.com/articles/nature05287
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http://dx.doi.org/10.1038/nature05287DOI Listing
November 2006

Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila.

Genes Dev 2004 Dec;18(23):2973-83

Institute of Genetics, Biologicum, Martin Luther University Halle, D-06120 Halle, Germany.

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http://dx.doi.org/10.1101/gad.323004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534657PMC
December 2004

A crack in histone lysine methylation.

Cell 2004 Dec;119(7):903-6

Research Institute of Molecular Pathology, The Vienna Biocenter, Dr. Bohrgasse 7, A-1030 Vienna, Austria.

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http://dx.doi.org/10.1016/j.cell.2004.12.006DOI Listing
December 2004

New Rebek imide-type receptors for adenine featuring acetylene-linked pi-stacking platforms.

Org Biomol Chem 2004 Jul 10;2(14):1962-4. Epub 2004 Jun 10.

Laboratorium fur Organische Chemie, ETH-Honggerberg, CH-8093 Zurich, Switzerland.

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http://dx.doi.org/10.1039/b404311aDOI Listing
July 2004