Stefan Krebs

Stefan Krebs

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Stefan Krebs

Stefan Krebs

Publications by authors named "Stefan Krebs"

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A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.

Nature 2020 03 4;579(7799):433-437. Epub 2020 Mar 4.

Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.

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http://dx.doi.org/10.1038/s41586-020-2076-4DOI Listing
March 2020

sp. nov., a novel species of the complex, occupying a basal position to North American species.

Int J Syst Evol Microbiol 2020 Feb;70(2):849-856

University of California, Department of Environmental Science, Policy and Management, Berkeley, CA, USA.

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http://dx.doi.org/10.1099/ijsem.0.003833DOI Listing
February 2020

Thrombolysis in Stroke With Unknown Onset Based on Non-Contrast Computerized Tomography (TRUST CT).

J Am Heart Assoc 2020 Feb 12;9(4):e014265. Epub 2020 Feb 12.

Department of Neurology with Focus on Neurovascular Diseases and Neurooncology and Hertie Institute for Clinical Brain Research University Hospital Tübingen Germany.

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http://dx.doi.org/10.1161/JAHA.119.014265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070213PMC
February 2020

Absolute nucleosome occupancy map for the genome.

Genome Res 2019 12 6;29(12):1996-2009. Epub 2019 Nov 6.

Molecular Biology Division, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1101/gr.253419.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886505PMC
December 2019

Baroreflex sensitivity is associated with post-stroke infections. An open, prospective study.

J Neurol Sci 2019 Nov 3;406:116450. Epub 2019 Sep 3.

Institute of Electronic Systems, Warsaw University of Technology, Poland.

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http://dx.doi.org/10.1016/j.jns.2019.116450DOI Listing
November 2019

Sex-specific programming effects of parental obesity in pre-implantation embryonic development.

Int J Obes (Lond) 2019 Nov 27. Epub 2019 Nov 27.

Institute of Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, Feodor-Lynen-Strasse 25, 81377, Munich, Germany.

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http://dx.doi.org/10.1038/s41366-019-0494-xDOI Listing
November 2019

Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.

Mol Metab 2019 08 4;26:30-44. Epub 2019 Jun 4.

Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, 81377 Munich, Germany; Center for Innovative Medical Models (CiMM), LMU Munich, 85764 Oberschleißheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667734PMC
August 2019

The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion.

Pigment Cell Melanoma Res 2019 05 21;32(3):424-434. Epub 2018 Dec 21.

Department of Dermatology and Allergy, University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1111/pcmr.12760DOI Listing
May 2019

Modified DWI-FLAIR mismatch guided thrombolysis in unknown onset stroke.

J Thromb Thrombolysis 2019 Feb;47(2):167-173

Department of Neurology, St. John's Hospital, Vienna, Austria.

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http://dx.doi.org/10.1007/s11239-018-1766-3DOI Listing
February 2019

Intravenous thrombolysis and mechanical thrombectomy in patients with minor or rapidly improving neurological deficits.

Curr Opin Neurol 2019 02;32(1):13-18

Department of Neurology, St. John's of God Hospital, Vienna, Austria.

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http://dx.doi.org/10.1097/WCO.0000000000000647DOI Listing
February 2019

Antigen-Specific TCR Signatures of Cytomegalovirus Infection.

J Immunol 2019 02 26;202(3):979-990. Epub 2018 Dec 26.

German Center for Infection Research Group Host Control of Viral Latency and Reactivation, Research Unit Gene Vectors, Helmholtz Center Munich, 81377 Munich, Germany;

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http://dx.doi.org/10.4049/jimmunol.1801401DOI Listing
February 2019

Heart rate variability is associated with outcome in spontaneous intracerebral hemorrhage.

J Crit Care 2018 12 25;48:85-89. Epub 2018 Aug 25.

Dept. of Neurology, St. John's Hospital Vienna, Medical Faculty, Sigmund Freud University, Vienna, Austria; Dept. of Neurology, University of Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08839441183096
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http://dx.doi.org/10.1016/j.jcrc.2018.08.033DOI Listing
December 2018

Genome-wide measurement of local nucleosome array regularity and spacing by nanopore sequencing.

Nat Struct Mol Biol 2018 09 20;25(9):894-901. Epub 2018 Aug 20.

Molecular Biology Division, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität , Munich, Germany.

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http://www.nature.com/articles/s41594-018-0110-0
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http://dx.doi.org/10.1038/s41594-018-0110-0DOI Listing
September 2018

Remapping of the belted phenotype in cattle on BTA3 identifies a multiplication event as the candidate causal mutation.

Genet Sel Evol 2018 07 6;50(1):36. Epub 2018 Jul 6.

Population Genomics Group, Department of Veterinary Sciences, LMU Munich, Veterinärstr. 13, 80539, Munich, Germany.

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http://dx.doi.org/10.1186/s12711-018-0407-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035435PMC
July 2018

Comparative genomics and the nature of placozoan species.

PLoS Biol 2018 07 31;16(7):e2005359. Epub 2018 Jul 31.

Department of Earth and Environmental Sciences, Paleontology and Geobiology, Ludwig-Maximilians-Universität München, Munich, Germany.

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https://dx.plos.org/10.1371/journal.pbio.2005359
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http://dx.doi.org/10.1371/journal.pbio.2005359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067683PMC
July 2018

IPEX due to an exon 7 skipping FOXP3 mutation with autoimmune diabetes mellitus cured by selective T cell engraftment.

Clin Immunol 2018 06 19;191:52-58. Epub 2018 Mar 19.

Pediatric Hematology/Oncology/Immunology, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.03.008DOI Listing
June 2018

Shortening the Application Time of Alcohol-Based Hand Rubs to 15 Seconds May Improve the Frequency of Hand Antisepsis Actions in a Neonatal Intensive Care Unit.

Infect Control Hosp Epidemiol 2017 12 30;38(12):1430-1434. Epub 2017 Oct 30.

3Department of Infection Control and Hospital Epidemiology,Medical University of Vienna,Vienna General Hospital,Vienna,Austria.

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http://dx.doi.org/10.1017/ice.2017.217DOI Listing
December 2017

Effect of metabolic status on conceptus-maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome.

Biol Reprod 2017 Sep;97(3):413-425

Division of Reproduction and Early Development, Faculty of Medicine and Health Sciences, University of Leeds, UK.

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http://dx.doi.org/10.1093/biolre/iox095DOI Listing
September 2017

The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.

Mol Metab 2017 08 13;6(8):931-940. Epub 2017 Jun 13.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, and Center for Innovative Medical Models (CiMM), LMU Munich, Feodor-Lynen-Str. 25, D-81377 Munich, Germany; German Center for Diabetes Research (DZD), Ingolstädter Landstr. 1, D-85764 Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, D-81377 Munich, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778173031
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http://dx.doi.org/10.1016/j.molmet.2017.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518720PMC
August 2017

Splicing stimulates siRNA formation at Drosophila DNA double-strand breaks.

PLoS Genet 2017 Jun 19;13(6):e1006861. Epub 2017 Jun 19.

Gene Center and Dept. of Biochemistry, Ludwig-Maximilians-Universität München, München, Germany.

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http://dx.doi.org/10.1371/journal.pgen.1006861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495518PMC
June 2017

Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1.

Sci Rep 2017 05 10;7(1):1684. Epub 2017 May 10.

Department of Molecular Epigenetics, Helmholtz Center Munich and Center for Integrated Protein Science Munich (CIPSM), Marchioninistrasse 25, 81377, Munich, Germany.

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http://dx.doi.org/10.1038/s41598-017-01943-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431861PMC
May 2017

Do Women With Atrial Fibrillation Experience More Severe Strokes? Results From the Austrian Stroke Unit Registry.

Stroke 2017 03 1;48(3):778-780. Epub 2017 Feb 1.

From the Department of Neurology, Hospital St. John of God, Vienna, Austria (C.L., J.F., S. Krebs, W.L.); Austrian Institute for Health Care (Österreichisches Bundesinstitut für Gesundheitswesen), Vienna, Austria (L.S.); Department of Neurology, Medical University of Graz, Austria (T.G.); Department of Neurology, Medical University Vienna, Austria (S.G.); Department for Clinical Neurosciences, Danube University, Krems, Austria (M.B.); Department of Neurology, Medical University of Innsbruck, Austria (K.W., T.T, S. Kiechl, J.W., M.K.); and Medical Faculty, Sigmund Freud University, Vienna, Austria (W.L.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015900DOI Listing
March 2017

TT-seq captures enhancer landscapes immediately after T-cell stimulation.

Mol Syst Biol 2017 03 7;13(3):920. Epub 2017 Mar 7.

Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371733PMC
http://dx.doi.org/10.15252/msb.20167507DOI Listing
March 2017

The 1.78-kb insertion in the 3'-untranslated region of RXFP2 does not segregate with horn status in sheep breeds with variable horn status.

Genet Sel Evol 2016 10 19;48(1):78. Epub 2016 Oct 19.

Chair of Animal Genetics and Husbandry, LMU Munich, Veterinaerstrasse 13, 80539, Munich, Germany.

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http://dx.doi.org/10.1186/s12711-016-0256-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072343PMC
October 2016

Recurrent evolution of host and vector association in bacteria of the Borrelia burgdorferi sensu lato species complex.

BMC Genomics 2016 09 15;17(1):734. Epub 2016 Sep 15.

National Reference Centre for Borrelia at the Bavarian Health and Food Safety Authority, Veterinärstr. 2, 85764, Oberschleissheim, Germany.

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http://dx.doi.org/10.1186/s12864-016-3016-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025617PMC
September 2016

Predictive value of ABCD2 and ABCD3-I scores in TIA and minor stroke in the stroke unit setting.

Neurology 2016 Aug 29;87(9):861-9. Epub 2016 Jul 29.

From the Department of Neurology (M.K., B.M., T.T., S. Kiechl, J.W.), Innsbruck Medical University; Department of Neurology (W.L., S. Krebs, J.F.), Hospital Barmherzige Brueder; Danube University Krems and Gesundheit Österreich GmbH/BIQG (L.S.); Department of Neurology (E.F.), Hospital Rudolfstiftung, Vienna; Department of Neurology (S.O.), University Clinic St Pölten; Department of Neurology (G.D.), Hospital Wilhelminenspital, Wien; Department of Neurology (T.S.-H.), Medical University of Graz; Department of Clinical Neurosciences and Preventive Medicine (M.B.), Danube University Krems; and Department of Neurology (M.B.), Karl Landsteiner University Hospital Tulln, Austria.

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http://dx.doi.org/10.1212/WNL.0000000000003033DOI Listing
August 2016

Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia.

Genes Chromosomes Cancer 2016 07 2;55(7):553-67. Epub 2016 May 2.

Experimental Leukemia and Lymphoma Research (ELLF), Department of Internal Medicine III, University Hospital of the Ludwig-Maximilians-Universität (LMU) München, Munich, Germany.

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http://dx.doi.org/10.1002/gcc.22359DOI Listing
July 2016

TRAPLINE: a standardized and automated pipeline for RNA sequencing data analysis, evaluation and annotation.

BMC Bioinformatics 2016 Jan 6;17:21. Epub 2016 Jan 6.

Department of Systems Biology and Bioinformatics, University of Rostock, 18057, Rostock, Germany.

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http://dx.doi.org/10.1186/s12859-015-0873-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702420PMC
January 2016

Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation.

Leuk Res Rep 2015 17;4(2):72-5. Epub 2015 Oct 17.

Department of Hematology and Vascular Disorders, Skåne University Hospital, 22185 Lund, Sweden ; Department of Molecular Medicine and Gene Therapy, Sölvegatan 17, BMC A12, Lund University, 22184 Lund, Sweden.

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http://dx.doi.org/10.1016/j.lrr.2015.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672090PMC
December 2015

Lack of Rybp in Mouse Embryonic Stem Cells Impairs Cardiac Differentiation.

Stem Cells Dev 2015 Sep 25;24(18):2193-205. Epub 2015 Jun 25.

2 Institute of Genetics , Biological Research Centre, Hungarian Academy of Sciences, Szeged, Hungary .

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http://dx.doi.org/10.1089/scd.2014.0569DOI Listing
September 2015

Comparing effects of perfusion and hydrostatic pressure on gene profiles of human chondrocyte.

J Biotechnol 2015 Sep 29;210:59-65. Epub 2015 Jun 29.

Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, Campus Großhadern, Ludwig-Maximilians-University, Marchioninistr. 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1016/j.jbiotec.2015.06.409DOI Listing
September 2015

Parapoxvirus (PPV) of red deer reveals subclinical infection and confirms a unique species.

J Gen Virol 2015 Jun 20;96(Pt 6):1446-1462. Epub 2015 Feb 20.

Bavarian Health and Food Safety Authority, Oberschleißheim, Germany.

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http://dx.doi.org/10.1099/vir.0.000080DOI Listing
June 2015

NGS population genetics analyses reveal divergent evolution of a Lyme Borreliosis agent in Europe and Asia.

Ticks Tick Borne Dis 2015 Apr 10;6(3):344-51. Epub 2015 Mar 10.

LMU Munich, Department Biology II, Großhaderner Str. 2, 82152 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ttbdis.2015.02.008DOI Listing
April 2015

Next generation sequencing analysis of nine Corynebacterium ulcerans isolates reveals zoonotic transmission and a novel putative diphtheria toxin-encoding pathogenicity island.

Genome Med 2014 28;6(11):113. Epub 2014 Nov 28.

LGL, Bavarian Health and Food Safety Authority, Oberschleißheim, 85764 Germany ; National Consiliary Laboratory on Diphtheria, Oberschleißheim, 85764 Germany.

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http://dx.doi.org/10.1186/s13073-014-0113-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293111PMC
January 2015

Oxyphil cell metaplasia in the parathyroids is characterized by somatic mitochondrial DNA mutations in NADH dehydrogenase genes and cytochrome c oxidase activity-impairing genes.

Am J Pathol 2014 Nov;184(11):2922-35

Institute for Pathology of the Ludwig-Maximilians-Universität München, Munich, Germany; German Cancer Consortium and German Cancer Research Center, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440140043
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http://dx.doi.org/10.1016/j.ajpath.2014.07.015DOI Listing
November 2014

Genome activation in bovine embryos: review of the literature and new insights from RNA sequencing experiments.

Anim Reprod Sci 2014 Sep 6;149(1-2):46-58. Epub 2014 Jun 6.

Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany; Graduate School of Quantitative Biosciences (QBM), Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany; Chair for Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.anireprosci.2014.05.016DOI Listing
September 2014

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis.

Blood 2014 Aug 12;124(8):1304-11. Epub 2014 Jun 12.

Department of Internal Medicine 3, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany; Clinical Cooperative Group Leukemia, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany;

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http://dx.doi.org/10.1182/blood-2013-12-540716DOI Listing
August 2014

Uniformity of nucleosome preservation pattern in Mammalian sperm and its connection to repetitive DNA elements.

Dev Cell 2014 Jul 3;30(1):23-35. Epub 2014 Jul 3.

Clinic and Polyclinic of Urology, Pediatric Urology and Andrology, Department of Molecular Andrology, Justus Liebig University Giessen, 35392 Giessen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2014.05.023DOI Listing
July 2014

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells.

Carcinogenesis 2014 Apr 9;35(4):942-50. Epub 2013 Dec 9.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675 Munich, Germany.

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http://dx.doi.org/10.1093/carcin/bgt410DOI Listing
April 2014

Hypoxia-independent gene expression mediated by SOX9 promotes aggressive pancreatic tumor biology.

Mol Cancer Res 2014 Mar 3;12(3):421-32. Epub 2013 Dec 3.

Klinikum Großhadern, VH02 426, Marchioninistr. 15, 81377 München, Germany.

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http://dx.doi.org/10.1158/1541-7786.MCR-13-0351DOI Listing
March 2014

Comparative and retrospective molecular analysis of Parapoxvirus (PPV) isolates.

Virus Res 2014 Mar 27;181:11-21. Epub 2013 Dec 27.

Bavarian Health and Food Safety Authority, Oberschleissheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2013.12.015DOI Listing
March 2014

Fine mapping of genome activation in bovine embryos by RNA sequencing.

Proc Natl Acad Sci U S A 2014 Mar 3;111(11):4139-44. Epub 2014 Mar 3.

Laboratory for Functional Genome Analysis, Chair for Molecular Animal Breeding and Biotechnology, and Department of Biochemistry, Center for Integrated Protein Science, Gene Center, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.

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http://dx.doi.org/10.1073/pnas.1321569111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964062PMC
March 2014

Comprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signaling.

BMC Genomics 2014 Jan 28;15:74. Epub 2014 Jan 28.

Department of Medicine II, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1186/1471-2164-15-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909937PMC
January 2014

Transcriptome changes in the porcine endometrium during the preattachment phase.

Biol Reprod 2013 Dec 12;89(6):134. Epub 2013 Dec 12.

Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1095/biolreprod.113.112177DOI Listing
December 2013

Deep sequencing of the porcine endometrial transcriptome on day 14 of pregnancy.

Biol Reprod 2013 Apr 4;88(4):84. Epub 2013 Apr 4.

Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1095/biolreprod.113.107870DOI Listing
April 2013

A Comprehensive Gene Expression Analysis of Resistance Formation upon Metronomic Cyclophosphamide Therapy.

Transl Oncol 2013 Feb 1;6(1):1-9. Epub 2013 Feb 1.

Pharmaceutical Biotechnology, Department of Pharmacy, Center for System-Based Drug Research, Ludwig-Maximilians University, Munich, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573648PMC
http://dx.doi.org/10.1593/tlo.12295DOI Listing
February 2013

LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation.

Cell 2013 Jan;152(3):584-98

Department of Biology II, Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians University Munich, Grosshadernerstrasse 2, 82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1016/j.cell.2013.01.009DOI Listing
January 2013

Changing metabolic signatures of amino acids and lipids during the prediabetic period in a pig model with impaired incretin function and reduced β-cell mass.

Diabetes 2012 Aug 9;61(8):2166-75. Epub 2012 Apr 9.

Chair for Molecular Animal Breeding and Biotechnology, and Laboratory for Functional Genome Analysis, Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany.

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http://dx.doi.org/10.2337/db11-1133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402307PMC
August 2012