Stefan Kempa

Stefan Kempa

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Stefan Kempa

Stefan Kempa

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Corrigendum to Stage-specific metabolic features of differentiating neurons: Implications for toxicant sensitivity Toxicol Appl Pharmacol, 354 (2018) 64-80.

Toxicol Appl Pharmacol 2019 Jun 16;372:70. Epub 2019 Apr 16.

In Vitro Toxicology and Biomedicine, Dept Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457 Konstanz, Germany; CAAT-Europe, University of Konstanz, Konstanz 78457, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2019.04.010DOI Listing
June 2019

Stage-specific metabolic features of differentiating neurons: Implications for toxicant sensitivity.

Toxicol Appl Pharmacol 2018 09 24;354:64-80. Epub 2017 Dec 24.

In Vitro Toxicology and Biomedicine, Dept Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457 Konstanz, Germany; CAAT-Europe, University of Konstanz, Konstanz 78457, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2017.12.013DOI Listing
September 2018

Muscle Atrophy Due to Nerve Damage Is Accompanied by Elevated Myofibrillar Protein Synthesis Rates.

Front Physiol 2018 31;9:1220. Epub 2018 Aug 31.

Experimental and Clinical Research Center, a Joint Cooperation of Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.3389/fphys.2018.01220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127268PMC
August 2018

Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: A comprehensive examination of the potential carriers for semiochemicals.

J Proteomics 2018 06 10;181:131-141. Epub 2018 Apr 10.

Biology Department, University of Firenze, via Madonna del Piano 6, 50019 Sesto Fiorentino, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2018.04.009DOI Listing
June 2018

Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.

Sci Rep 2018 Jun 15;8(1):9204. Epub 2018 Jun 15.

Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute of Health (BIH), Robert-Roessle-Str. 10, 13125, Berlin, Germany.

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http://dx.doi.org/10.1038/s41598-018-27394-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003911PMC
June 2018

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.

Genes Dev 2018 05 10;32(9-10):645-657. Epub 2018 May 10.

Department of Developmental Biology/Signal Transduction, Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.

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http://dx.doi.org/10.1101/gad.310490.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004071PMC
May 2018

Retinol saturase coordinates liver metabolism by regulating ChREBP activity.

Nat Commun 2017 08 30;8(1):384. Epub 2017 Aug 30.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, 10115, Germany.

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http://dx.doi.org/10.1038/s41467-017-00430-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577314PMC
August 2017

The mRNA 3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.

EMBO J 2017 07 13;36(13):1854-1868. Epub 2017 Apr 13.

Theodor Boveri Institute and Comprehensive Cancer Center Mainfranken, Biocenter, University of Würzburg, Würzburg, Germany

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http://dx.doi.org/10.15252/embj.201796662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494468PMC
July 2017

The answer's in the tail: MYC mRNA has a metabolic sensor that supports cancer chemoresistance.

Mol Cell Oncol 2017 5;4(4):e1338209. Epub 2017 Jul 5.

Integrative proteomics and metabolomics, Berlin Institute for Medical Systems Biology at the Max Delbrueck Center for Molecular Medicine, Berlin, Germany.

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http://dx.doi.org/10.1080/23723556.2017.1338209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540213PMC
July 2017

Quantitative Analysis of Cancer Metabolism: From pSIRM to MFA.

Recent Results Cancer Res 2016;207:207-20

Integrative Proteomics and Metabolomics, Max-Delbrueck-Center of Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.

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http://dx.doi.org/10.1007/978-3-319-42118-6_9DOI Listing
March 2017

On Mass Ambiguities in High-Resolution Shotgun Lipidomics.

Anal Chem 2017 03 21;89(5):2986-2994. Epub 2017 Feb 21.

Berlin Institute of Health Technology Platform Metabolomics, Max-Delbrück-Centrum for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin-Buch, Germany.

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http://dx.doi.org/10.1021/acs.analchem.6b04456DOI Listing
March 2017

Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.

J Cell Sci 2017 03 13;130(6):1122-1133. Epub 2017 Feb 13.

Leibniz-Institut für Molekulare Pharmakologie (FMP), D-13125 Berlin, Germany

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http://dx.doi.org/10.1242/jcs.196253DOI Listing
March 2017

Proteomics Quality Control: Quality Control Software for MaxQuant Results.

J Proteome Res 2016 Mar 28;15(3):777-87. Epub 2015 Dec 28.

Max-Delbrück-Centrum for Molecular Medicine Berlin , Robert-Rössle-Straße 10, 13125 Berlin, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.5b00780DOI Listing
March 2016

A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.

Cancer Cell 2015 Dec;28(6):743-757

Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany; Comprehensive Cancer Center Mainfranken, University of Würzburg, Josef-Schneider-Straße 6, 97080 Würzburg, Germany. Electronic address:

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http://www.cell.com/cancer-cell/pdf/S1535-6108(15)00390-6.pd
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http://linkinghub.elsevier.com/retrieve/pii/S153561081500390
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http://dx.doi.org/10.1016/j.ccell.2015.10.013DOI Listing
December 2015

Extensive identification and analysis of conserved small ORFs in animals.

Genome Biol 2015 Sep 14;16:179. Epub 2015 Sep 14.

Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Str. 10, 13125, Berlin, Germany.

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http://dx.doi.org/10.1186/s13059-015-0742-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568590PMC
September 2015

Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells.

Cell Metab 2015 Mar;21(3):392-402

Grass Center for Bioengineering, Hebrew University of Jerusalem, Jerusalem 9190401, Israel; Alexander Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem 9190401, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.02.002DOI Listing
March 2015

Pulsed stable isotope-resolved metabolomic studies of cancer cells.

Methods Enzymol 2014 ;543:179-98

Berlin Institute for Medical Systems Biology at the MDC Berlin-Buch, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-801329-8.00009-XDOI Listing
February 2015

Maui-VIA: A User-Friendly Software for Visual Identification, Alignment, Correction, and Quantification of Gas Chromatography-Mass Spectrometry Data.

Front Bioeng Biotechnol 2014 21;2:84. Epub 2015 Jan 21.

Integrative Proteomics and Metabolomics, Berlin Institute of Health , Berlin , Germany ; Integrative Proteomics and Metabolomics, Berlin Institute for Medical Systems Biology/Max Delbrück Center for Molecular Medicine , Berlin , Germany.

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http://dx.doi.org/10.3389/fbioe.2014.00084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301187PMC
February 2015

Decoding the dynamics of cellular metabolism and the action of 3-bromopyruvate and 2-deoxyglucose using pulsed stable isotope-resolved metabolomics.

Cancer Metab 2014 30;2. Epub 2014 Jun 30.

Integrative Metabolomics and Proteomics, Berlin Institute of Medical Systems Biology/Max-Delbrueck Center for Molecular Medicine, Robert Rossle Street 10, Berlin 13125, Germany.

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http://dx.doi.org/10.1186/2049-3002-2-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101711PMC
July 2014

MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.

Mol Cell 2014 May 10;54(4):573-85. Epub 2014 Apr 10.

Max-Delbrück-Center for Molecular Medicine, Berlin Institute for Medical Systems Biology, 13125 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.03.017DOI Listing
May 2014

Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.

RNA Biol 2013 Jul 29;10(7):1146-59. Epub 2013 May 29.

Systems Biology of Gene Regulatory Elements; Max-Delbrück-Center for Molecular Medicine; Berlin, Germany.

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http://dx.doi.org/10.4161/rna.25194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849162PMC
July 2013

Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells.

EMBO J 2012 Jun 27;31(12):2755-69. Epub 2012 Apr 27.

Laboratory of Systems Biology of Gene Regulatory Elements, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.

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http://dx.doi.org/10.1038/emboj.2012.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380209PMC
June 2012

Proteome dynamics and early salt stress response of the photosynthetic organism Chlamydomonas reinhardtii.

BMC Genomics 2012 May 31;13:215. Epub 2012 May 31.

Max Delbrück Center for Molecular Medicine Berlin, Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany.

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http://dx.doi.org/10.1186/1471-2164-13-215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444938PMC
May 2012

Deregulated MYC expression induces dependence upon AMPK-related kinase 5.

Nature 2012 Mar 28;483(7391):608-12. Epub 2012 Mar 28.

Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1038/nature10927DOI Listing
March 2012

In vivo and transcriptome-wide identification of RNA binding protein target sites.

Mol Cell 2011 Dec;44(5):828-40

Systems Biology of Gene Regulatory Elements, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.

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http://dx.doi.org/10.1016/j.molcel.2011.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253457PMC
December 2011

Expression of root glutamate dehydrogenase genes in tobacco plants subjected to boron deprivation.

Plant Physiol Biochem 2011 Nov 12;49(11):1350-4. Epub 2011 Jun 12.

Departamento de Fisiología, Anatomía y Biología Celular, Universidad Pablo de Olavide, E-41013 Sevilla, Spain.

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http://dx.doi.org/10.1016/j.plaphy.2011.06.001DOI Listing
November 2011

An integrative approach towards completing genome-scale metabolic networks.

Mol Biosyst 2009 Dec 10;5(12):1889-903. Epub 2009 Sep 10.

Max-Planck-Institute for Molecular Plant Physiology, Potsdam-Golm, Germany.

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http://dx.doi.org/10.1039/B915913bDOI Listing
December 2009

ChlamyCyc: an integrative systems biology database and web-portal for Chlamydomonas reinhardtii.

BMC Genomics 2009 May 4;10:209. Epub 2009 May 4.

Max-Planck-Institute of Molecular Plant Physiology, Potsdam, Germany.

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http://dx.doi.org/10.1186/1471-2164-10-209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688524PMC
May 2009

A plastid-localized glycogen synthase kinase 3 modulates stress tolerance and carbohydrate metabolism.

Plant J 2007 Mar 22;49(6):1076-90. Epub 2007 Feb 22.

Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Vienna Biocenter, A-1030 Vienna, Austria.

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http://dx.doi.org/10.1111/j.1365-313X.2006.03025.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865003PMC
March 2007

Towards dissecting nutrient metabolism in plants: a systems biology case study on sulphur metabolism.

J Exp Bot 2004 Aug 18;55(404):1861-70. Epub 2004 Jun 18.

Max-Planck-Institut für Molekulare Pflanzenphysiologie, Department of Molecular Physiology, Am Mühlenberg 1, D-14476 Golm, Germany.

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http://dx.doi.org/10.1093/jxb/erh177DOI Listing
August 2004

Muscle-type creatine kinase interacts with central domains of the M-band proteins myomesin and M-protein.

J Mol Biol 2003 Sep;332(4):877-87

Institute of Cell Biology, Swiss Federal Institute of Technology, CH-8093 Zürich, Switzerland.

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September 2003

Transcriptome analysis of sulfur depletion in Arabidopsis thaliana: interlacing of biosynthetic pathways provides response specificity.

Plant J 2003 Feb;33(4):633-50

Department 1 of L. Willmitzer, Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476 Golm, Germany.

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February 2003