Stefan Kempa

Stefan Kempa

UNVERIFIED PROFILE

Are you Stefan Kempa?   Register this Author

Register author
Stefan Kempa

Stefan Kempa

Publications by authors named "Stefan Kempa"

Are you Stefan Kempa?   Register this Author

57Publications

1021Reads

-Profile Views

Corrigendum to Stage-specific metabolic features of differentiating neurons: Implications for toxicant sensitivity Toxicol Appl Pharmacol, 354 (2018) 64-80.

Authors:
Johannes Delp Simon Gutbier Martin Cerff Christin Zasada Sebastian Niedenführ Liang Zhao Lena Smirnova Thomas Hartung Hanna Borlinghaus Falk Schreiber Jörg Bergemann Jochem Gätgens Martin Beyss Salah Azzouzi Tanja Waldmann Stefan Kempa Katharina Nöh Marcel Leist

Toxicol Appl Pharmacol 2019 Jun 16;372:70. Epub 2019 Apr 16.

In Vitro Toxicology and Biomedicine, Dept Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457 Konstanz, Germany; CAAT-Europe, University of Konstanz, Konstanz 78457, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.taap.2019.04.010DOI Listing
June 2019

Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.

Authors:
Nadine Rohwer Sandra Jumpertz Merve Erdem Antje Egners Klaudia T Warzecha Athanassios Fragoulis Anja A Kühl Rafael Kramann Sabine Neuss Ines Rudolph Tobias Endermann Christin Zasada Ivayla Apostolova Marco Gerling Stefan Kempa Russell Hughes Claire E Lewis Winfried Brenner Maciej B Malinowski Martin Stockmann Lutz Schomburg William Faller Owen J Sansom Frank Tacke Markus Morkel Thorsten Cramer

Oncogene 2019 May 1. Epub 2019 May 1.

Molecular Tumor Biology, Department of General Visceral and Transplantation Surgery, RWTH University Hospital, Pauwelsstraße 30, 52074, Aachen, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/s41388-019-0816-4DOI Listing
May 2019

Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage.

Authors:
Hendrik Bartolomaeus András Balogh Mina Yakoub Susanne Homann Lajos Markó Sascha Höges Dmitry Tsvetkov Alexander Krannich Sebastian Wundersitz Ellen G Avery Nadine Haase Kristin Kräker Lydia Hering Martina Maase Kristina Kusche-Vihrog Maria Grandoch Jens Fielitz Stefan Kempa Maik Gollasch Zhaxybay Zhumadilov Samat Kozhakhmetov Almagul Kushugulova Kai-Uwe Eckardt Ralf Dechend Lars Christian Rump Sofia K Forslund Dominik N Müller Johannes Stegbauer Nicola Wilck

Circulation 2019 Mar;139(11):1407-1421

Experimental and Clinical Research Center, a Cooperation of Charité-Universitätsmedizin Berlin and Max Delbruck Center for Molecular Medicine, Germany (H.B., A.B., L.M., D.T., S.W., E.G.A., N.H., K.K., J.F., M.G., R.D., S.K.F., D.N.M., N.W.).

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416008PMC
March 2019

Stage-specific metabolic features of differentiating neurons: Implications for toxicant sensitivity.

Authors:
Johannes Delp Simon Gutbier Martin Cerff Christin Zasada Sebastian Niedenführ Liang Zhao Lena Smirnova Thomas Hartung Hanna Borlinghaus Falk Schreiber Jörg Bergemann Jochem Gätgens Martin Beyss Salah Azzouzi Tanja Waldmann Stefan Kempa Katharina Nöh Marcel Leist

Toxicol Appl Pharmacol 2018 09 24;354:64-80. Epub 2017 Dec 24.

In Vitro Toxicology and Biomedicine, Dept Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457 Konstanz, Germany; CAAT-Europe, University of Konstanz, Konstanz 78457, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.taap.2017.12.013DOI Listing
September 2018

Corrigendum: Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.

Authors:
Minchul Kim Hagen Wende Jan Walcher Johannes Kühnemund Cyril Cheret Stefan Kempa Erik McShane Matthias Selbach Gary R Lewis Carmen Birchmeier

Genes Dev 2018 08;32(15-16):1101

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1101/gad.318477.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075150PMC
August 2018

Muscle Atrophy Due to Nerve Damage Is Accompanied by Elevated Myofibrillar Protein Synthesis Rates.

Authors:
Henning T Langer Joan M G Senden Annemie P Gijsen Stefan Kempa Luc J C van Loon Simone Spuler

Front Physiol 2018 31;9:1220. Epub 2018 Aug 31.

Experimental and Clinical Research Center, a Joint Cooperation of Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.3389/fphys.2018.01220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127268PMC
August 2018

Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: A comprehensive examination of the potential carriers for semiochemicals.

Authors:
Immacolata Iovinella Alison McAfee Guido Mastrobuoni Stefan Kempa Leonard J Foster Paolo Pelosi Francesca Romana Dani

J Proteomics 2018 06 10;181:131-141. Epub 2018 Apr 10.

Biology Department, University of Firenze, via Madonna del Piano 6, 50019 Sesto Fiorentino, Italy. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.jprot.2018.04.009DOI Listing
June 2018

Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.

Authors:
Raphaela Fritsche-Guenther Christin Zasada Guido Mastrobuoni Nadine Royla Roman Rainer Florian Roßner Matthias Pietzke Edda Klipp Christine Sers Stefan Kempa

Sci Rep 2018 Jun 15;8(1):9204. Epub 2018 Jun 15.

Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute of Health (BIH), Robert-Roessle-Str. 10, 13125, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/s41598-018-27394-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003911PMC
June 2018

Combined Human Genome-wide RNAi and Metabolite Analyses Identify IMPDH as a Host-Directed Target against Chlamydia Infection.

Authors:
Marion Rother Erik Gonzalez Ana Rita Teixeira da Costa Lea Wask Isabella Gravenstein Matteo Pardo Matthias Pietzke Rajendra Kumar Gurumurthy Jörg Angermann Robert Laudeley Silke Glage Michael Meyer Cindrilla Chumduri Stefan Kempa Klaus Dinkel Anke Unger Bert Klebl Andreas Klos Thomas F Meyer

Cell Host Microbe 2018 05 26;23(5):661-671.e8. Epub 2018 Apr 26.

Max Planck Institute for Infection Biology, Department of Molecular Biology, Charitéplatz 1, 10117 Berlin, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.chom.2018.04.002DOI Listing
May 2018

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.

Authors:
Minchul Kim Hagen Wende Jan Walcher Johannes Kühnemund Cyril Cheret Stefan Kempa Erik McShane Matthias Selbach Gary R Lewin Carmen Birchmeier

Genes Dev 2018 05 10;32(9-10):645-657. Epub 2018 May 10.

Department of Developmental Biology/Signal Transduction, Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1101/gad.310490.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004071PMC
May 2018

Salt-responsive gut commensal modulates T17 axis and disease.

Authors:
Nicola Wilck Mariana G Matus Sean M Kearney Scott W Olesen Kristoffer Forslund Hendrik Bartolomaeus Stefanie Haase Anja Mähler András Balogh Lajos Markó Olga Vvedenskaya Friedrich H Kleiner Dmitry Tsvetkov Lars Klug Paul I Costea Shinichi Sunagawa Lisa Maier Natalia Rakova Valentin Schatz Patrick Neubert Christian Frätzer Alexander Krannich Maik Gollasch Diana A Grohme Beatriz F Côrte-Real Roman G Gerlach Marijana Basic Athanasios Typas Chuan Wu Jens M Titze Jonathan Jantsch Michael Boschmann Ralf Dechend Markus Kleinewietfeld Stefan Kempa Peer Bork Ralf A Linker Eric J Alm Dominik N Müller

Nature 2017 11 15;551(7682):585-589. Epub 2017 Nov 15.

Experimental and Clinical Research Center, a joint cooperation of Max-Delbrück Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, 13125 Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/nature24628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070150PMC
November 2017

Retinol saturase coordinates liver metabolism by regulating ChREBP activity.

Authors:
Steffi Heidenreich Nicole Witte Pamela Weber Isabel Goehring Alexander Tolkachov Christian von Loeffelholz Stephanie Döcke Michael Bauer Martin Stockmann Andreas F H Pfeiffer Andreas L Birkenfeld Matthias Pietzke Stefan Kempa Matthias Muenzner Michael Schupp

Nat Commun 2017 08 30;8(1):384. Epub 2017 Aug 30.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, 10115, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/s41467-017-00430-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577314PMC
August 2017

The mRNA 3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.

Authors:
Francesca R Dejure Nadine Royla Steffi Herold Jacqueline Kalb Susanne Walz Carsten P Ade Guido Mastrobuoni Jens T Vanselow Andreas Schlosser Elmar Wolf Stefan Kempa Martin Eilers

EMBO J 2017 07 13;36(13):1854-1868. Epub 2017 Apr 13.

Theodor Boveri Institute and Comprehensive Cancer Center Mainfranken, Biocenter, University of Würzburg, Würzburg, Germany

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.15252/embj.201796662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494468PMC
July 2017

The answer's in the tail: MYC mRNA has a metabolic sensor that supports cancer chemoresistance.

Authors:
Nadine Royla Stefan Kempa

Mol Cell Oncol 2017 5;4(4):e1338209. Epub 2017 Jul 5.

Integrative proteomics and metabolomics, Berlin Institute for Medical Systems Biology at the Max Delbrueck Center for Molecular Medicine, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1080/23723556.2017.1338209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540213PMC
July 2017

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.

Authors:
Gabriele Varano Simon Raffel Martina Sormani Federica Zanardi Silvia Lonardi Christin Zasada Laura Perucho Valentina Petrocelli Andrea Haake Albert K Lee Mattia Bugatti Ulrike Paul Eelco Van Anken Laura Pasqualucci Raul Rabadan Reiner Siebert Stefan Kempa Maurilio Ponzoni Fabio Facchetti Klaus Rajewsky Stefano Casola

Nature 2017 06 31;546(7657):302-306. Epub 2017 May 31.

IFOM, the FIRC Institute of Molecular Oncology, 20139 Milan, Italy.

View Article

Download full-text PDF

 Source
http://www.nature.com/doifinder/10.1038/nature22353
Publisher Site
http://dx.doi.org/10.1038/nature22353DOI Listing
June 2017

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.

Authors:
Thomas J Park Jane Reznick Bethany L Peterson Gregory Blass Damir Omerbašić Nigel C Bennett P Henning J L Kuich Christin Zasada Brigitte M Browe Wiebke Hamann Daniel T Applegate Michael H Radke Tetiana Kosten Heike Lutermann Victoria Gavaghan Ole Eigenbrod Valérie Bégay Vince G Amoroso Vidya Govind Richard D Minshall Ewan St J Smith John Larson Michael Gotthardt Stefan Kempa Gary R Lewin

Science 2017 04;356(6335):307-311

Molecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1126/science.aab3896DOI Listing
April 2017

Quantitative Analysis of Cancer Metabolism: From pSIRM to MFA.

Authors:
Christin Zasada Stefan Kempa

Recent Results Cancer Res 2016;207:207-20

Integrative Proteomics and Metabolomics, Max-Delbrueck-Center of Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1007/978-3-319-42118-6_9DOI Listing
March 2017

On Mass Ambiguities in High-Resolution Shotgun Lipidomics.

Authors:
Chris Bielow Guido Mastrobuoni Marica Orioli Stefan Kempa

Anal Chem 2017 03 21;89(5):2986-2994. Epub 2017 Feb 21.

Berlin Institute of Health Technology Platform Metabolomics, Max-Delbrück-Centrum for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin-Buch, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1021/acs.analchem.6b04456DOI Listing
March 2017

Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.

Authors:
Darius Lutter Florian Ullrich Jennifer C Lueck Stefan Kempa Thomas J Jentsch

J Cell Sci 2017 03 13;130(6):1122-1133. Epub 2017 Feb 13.

Leibniz-Institut für Molekulare Pharmakologie (FMP), D-13125 Berlin, Germany

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1242/jcs.196253DOI Listing
March 2017

SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity.

Authors:
Vanessa Schmidt Nadja Schulz Xin Yan Annette Schürmann Stefan Kempa Matthias Kern Matthias Blüher Matthew N Poy Gunilla Olivecrona Thomas E Willnow

J Clin Invest 2016 07 20;126(7):2706-20. Epub 2016 Jun 20.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1172/JCI84708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922706PMC
July 2016

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine.

Authors:
Aiden Haghikia Stefanie Jörg Alexander Duscha Johannes Berg Arndt Manzel Anne Waschbisch Anna Hammer De-Hyung Lee Caroline May Nicola Wilck Andras Balogh Annika I Ostermann Nils Helge Schebb Denis A Akkad Diana A Grohme Markus Kleinewietfeld Stefan Kempa Jan Thöne Seray Demir Dominik N Müller Ralf Gold Ralf A Linker

Immunity 2016 Apr;44(4):951-3

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.immuni.2016.04.006DOI Listing
April 2016

Proteomics Quality Control: Quality Control Software for MaxQuant Results.

Authors:
Chris Bielow Guido Mastrobuoni Stefan Kempa

J Proteome Res 2016 Mar 28;15(3):777-87. Epub 2015 Dec 28.

Max-Delbrück-Centrum for Molecular Medicine Berlin , Robert-Rössle-Straße 10, 13125 Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1021/acs.jproteome.5b00780DOI Listing
March 2016

Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.

Authors:
Nadine Rohwer Fabian Bindel Christina Grimm Suling J Lin Jessica Wappler Bertram Klinger Nils Blüthgen Ilona Du Bois Bernd Schmeck Hans Lehrach Marjo de Graauw Emanuel Goncalves Julio Saez-Rodriguez Patrick Tan Heike I Grabsch Alessandro Prigione Stefan Kempa Thorsten Cramer

Oncotarget 2016 Feb;7(6):6693-710

Molecular Tumor Biology, Department of General, Visceral and Transplantation Surgery, RWTH University Hospital, Aachen, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.18632/oncotarget.6793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872743PMC
February 2016

Effects of RAF inhibitors on PI3K/AKT signalling depend on mutational status of the RAS/RAF signalling axis.

Authors:
Raphaela Fritsche-Guenther Franziska Witzel Stefan Kempa Tilman Brummer Christine Sers Nils Blüthgen

Oncotarget 2016 Feb;7(7):7960-9

Institute of Pathology, Molecular Tumor Pathology, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany.

View Article

Download full-text PDF

 Source
http://edoc.mdc-berlin.de/15399/1/15399oa.pdf
Web Search
http://www.oncotarget.com/abstract/6959
Publisher Site
http://dx.doi.org/10.18632/oncotarget.6959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884967PMC
February 2016

IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.

Authors:
Jan Naujoks Christoph Tabeling Brian D Dill Christine Hoffmann Andrew S Brown Mareike Kunze Stefan Kempa Andrea Peter Hans-Joachim Mollenkopf Anca Dorhoi Olivia Kershaw Achim D Gruber Leif E Sander Martin Witzenrath Susanne Herold Andreas Nerlich Andreas C Hocke Ian van Driel Norbert Suttorp Sammy Bedoui Hubert Hilbi Matthias Trost Bastian Opitz

PLoS Pathog 2016 Feb 1;12(2):e1005408. Epub 2016 Feb 1.

Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1371/journal.ppat.1005408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734697PMC
February 2016

A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.

Authors:
Björn von Eyss Laura A Jaenicke Roderik M Kortlever Nadine Royla Katrin E Wiese Sebastian Letschert Leigh-Anne McDuffus Markus Sauer Andreas Rosenwald Gerard I Evan Stefan Kempa Martin Eilers

Cancer Cell 2015 Dec;28(6):743-757

Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany; Comprehensive Cancer Center Mainfranken, University of Würzburg, Josef-Schneider-Straße 6, 97080 Würzburg, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://www.cell.com/cancer-cell/pdf/S1535-6108(15)00390-6.pd
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S153561081500390
Publisher Site
http://dx.doi.org/10.1016/j.ccell.2015.10.013DOI Listing
December 2015

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine.

Authors:
Aiden Haghikia Stefanie Jörg Alexander Duscha Johannes Berg Arndt Manzel Anne Waschbisch Anna Hammer De-Hyung Lee Caroline May Nicola Wilck Andras Balogh Annika I Ostermann Nils Helge Schebb Denis A Akkad Diana A Grohme Markus Kleinewietfeld Stefan Kempa Jan Thöne Seray Demir Dominik N Müller Ralf Gold Ralf A Linker

Immunity 2015 Oct;43(4):817-29

Department of Neurology, Friedrich-Alexander-University Erlangen-Nuremberg, 91054 Erlangen, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.immuni.2015.09.007DOI Listing
October 2015

Extensive identification and analysis of conserved small ORFs in animals.

Authors:
Sebastian D Mackowiak Henrik Zauber Chris Bielow Denise Thiel Kamila Kutz Lorenzo Calviello Guido Mastrobuoni Nikolaus Rajewsky Stefan Kempa Matthias Selbach Benedikt Obermayer

Genome Biol 2015 Sep 14;16:179. Epub 2015 Sep 14.

Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Str. 10, 13125, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1186/s13059-015-0742-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568590PMC
September 2015

Crosstalk between Two bZIP Signaling Pathways Orchestrates Salt-Induced Metabolic Reprogramming in Arabidopsis Roots.

Authors:
Laura Hartmann Lorenzo Pedrotti Christoph Weiste Agnes Fekete Jasper Schierstaedt Jasmin Göttler Stefan Kempa Markus Krischke Katrin Dietrich Martin J Mueller Jesus Vicente-Carbajosa Johannes Hanson Wolfgang Dröge-Laser

Plant Cell 2015 Aug 14;27(8):2244-60. Epub 2015 Aug 14.

Julius-von-Sachs-Institut, Pharmazeutische Biologie, Universität Würzburg, 97082 Würzburg, Germany

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1105/tpc.15.00163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568499PMC
August 2015

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.

Authors:
Yasuhiro Murakawa Michael Hinz Janina Mothes Anja Schuetz Michael Uhl Emanuel Wyler Tomoharu Yasuda Guido Mastrobuoni Caroline C Friedel Lars Dölken Stefan Kempa Marc Schmidt-Supprian Nils Blüthgen Rolf Backofen Udo Heinemann Jana Wolf Claus Scheidereit Markus Landthaler

Nat Commun 2015 Jul 14;6:7367. Epub 2015 Jul 14.

RNA Biology and Posttranscriptional Regulation, Berlin Institute of Medical Systems Biology at the Max-Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/ncomms8367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510711PMC
July 2015

Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells.

Authors:
Arieh Moussaieff Matthieu Rouleau Daniel Kitsberg Merav Cohen Gahl Levy Dinorah Barasch Alina Nemirovski Shai Shen-Orr Ilana Laevsky Michal Amit David Bomze Bénédicte Elena-Herrmann Tali Scherf Malka Nissim-Rafinia Stefan Kempa Joseph Itskovitz-Eldor Eran Meshorer Daniel Aberdam Yaakov Nahmias

Cell Metab 2015 Mar;21(3):392-402

Grass Center for Bioengineering, Hebrew University of Jerusalem, Jerusalem 9190401, Israel; Alexander Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem 9190401, Israel. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.cmet.2015.02.002DOI Listing
March 2015

Pulsed stable isotope-resolved metabolomic studies of cancer cells.

Authors:
Matthias Pietzke Stefan Kempa

Methods Enzymol 2014 ;543:179-98

Berlin Institute for Medical Systems Biology at the MDC Berlin-Buch, Berlin, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/B978-0-12-801329-8.00009-XDOI Listing
February 2015

Maui-VIA: A User-Friendly Software for Visual Identification, Alignment, Correction, and Quantification of Gas Chromatography-Mass Spectrometry Data.

Authors:
P Henning J L Kuich Nils Hoffmann Stefan Kempa

Front Bioeng Biotechnol 2014 21;2:84. Epub 2015 Jan 21.

Integrative Proteomics and Metabolomics, Berlin Institute of Health , Berlin , Germany ; Integrative Proteomics and Metabolomics, Berlin Institute for Medical Systems Biology/Max Delbrück Center for Molecular Medicine , Berlin , Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.3389/fbioe.2014.00084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301187PMC
February 2015

A proteomic investigation of soluble olfactory proteins in Anopheles gambiae.

Authors:
Guido Mastrobuoni Huili Qiao Immacolata Iovinella Simona Sagona Alberto Niccolini Francesca Boscaro Beniamino Caputo Marta R Orejuela Alessandra Della Torre Stefan Kempa Antonio Felicioli Paolo Pelosi Gloriano Moneti Francesca Romana Dani

PLoS One 2013 25;8(11):e75162. Epub 2013 Nov 25.

Integrative Proteomics and Metabolomics, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075162PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839933PMC
January 2015

Decoding the dynamics of cellular metabolism and the action of 3-bromopyruvate and 2-deoxyglucose using pulsed stable isotope-resolved metabolomics.

Authors:
Matthias Pietzke Christin Zasada Susann Mudrich Stefan Kempa

Cancer Metab 2014 30;2. Epub 2014 Jun 30.

Integrative Metabolomics and Proteomics, Berlin Institute of Medical Systems Biology/Max-Delbrueck Center for Molecular Medicine, Robert Rossle Street 10, Berlin 13125, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1186/2049-3002-2-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101711PMC
July 2014

MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.

Authors:
Lea H Gregersen Markus Schueler Mathias Munschauer Guido Mastrobuoni Wei Chen Stefan Kempa Christoph Dieterich Markus Landthaler

Mol Cell 2014 May 10;54(4):573-85. Epub 2014 Apr 10.

Max-Delbrück-Center for Molecular Medicine, Berlin Institute for Medical Systems Biology, 13125 Berlin, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.molcel.2014.03.017DOI Listing
May 2014

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.

Authors:
Jan R Dörr Yong Yu Maja Milanovic Gregor Beuster Christin Zasada J Henry M Däbritz Jan Lisec Dido Lenze Anne Gerhardt Katharina Schleicher Susanne Kratzat Bettina Purfürst Stefan Walenta Wolfgang Mueller-Klieser Markus Gräler Michael Hummel Ulrich Keller Andreas K Buck Bernd Dörken Lothar Willmitzer Maurice Reimann Stefan Kempa Soyoung Lee Clemens A Schmitt

Nature 2013 Sep 14;501(7467):421-5. Epub 2013 Aug 14.

Charité-Universitätsmedizin Berlin, Molekulares Krebsforschungszentrum, Augustenburger Platz 1, 13353 Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/nature12437DOI Listing
September 2013

Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.

Authors:
Robin Graf Mathias Munschauer Guido Mastrobuoni Florian Mayr Udo Heinemann Stefan Kempa Nikolaus Rajewsky Markus Landthaler

RNA Biol 2013 Jul 29;10(7):1146-59. Epub 2013 May 29.

Systems Biology of Gene Regulatory Elements; Max-Delbrück-Center for Molecular Medicine; Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.4161/rna.25194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849162PMC
July 2013

The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.

Authors:
Anne-Sophie Carlo Camilla Gustafsen Guido Mastrobuoni Morten S Nielsen Tilman Burgert Daniela Hartl Michael Rohe Anders Nykjaer Joachim Herz Joerg Heeren Stefan Kempa Claus Munck Petersen Thomas E Willnow

J Neurosci 2013 Jan;33(1):358-70

Max Delbrueck Center for Molecular Medicine, D-13125 Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1523/JNEUROSCI.2425-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744345PMC
January 2013

Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis.

Authors:
Silvia Dal Santo Hansjörg Stampfl Julia Krasensky Stefan Kempa Yves Gibon Elena Petutschnig Wilfried Rozhon Alexander Heuck Tim Clausen Claudia Jonak

Plant Cell 2012 Aug 10;24(8):3380-92. Epub 2012 Aug 10.

Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, 1030 Viena, Austria.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1105/tpc.112.101279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462638PMC
August 2012

Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells.

Authors:
Pinar Onal Dominic Grün Catherine Adamidi Agnieszka Rybak Jordi Solana Guido Mastrobuoni Yongbo Wang Hans-Peter Rahn Wei Chen Stefan Kempa Ulrike Ziebold Nikolaus Rajewsky

EMBO J 2012 Jun 27;31(12):2755-69. Epub 2012 Apr 27.

Laboratory of Systems Biology of Gene Regulatory Elements, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/emboj.2012.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380209PMC
June 2012

Proteome dynamics and early salt stress response of the photosynthetic organism Chlamydomonas reinhardtii.

Authors:
Guido Mastrobuoni Susann Irgang Matthias Pietzke Heike E Assmus Markus Wenzel Waltraud X Schulze Stefan Kempa

BMC Genomics 2012 May 31;13:215. Epub 2012 May 31.

Max Delbrück Center for Molecular Medicine Berlin, Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1186/1471-2164-13-215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444938PMC
May 2012

Deregulated MYC expression induces dependence upon AMPK-related kinase 5.

Authors:
Lidan Liu Jannes Ulbrich Judith Müller Torsten Wüstefeld Lukas Aeberhard Theresia R Kress Nathiya Muthalagu Lukas Rycak Ramona Rudalska Roland Moll Stefan Kempa Lars Zender Martin Eilers Daniel J Murphy

Nature 2012 Mar 28;483(7391):608-12. Epub 2012 Mar 28.

Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/nature10927DOI Listing
March 2012

In vivo and transcriptome-wide identification of RNA binding protein target sites.

Authors:
Anna-Carina Jungkamp Marlon Stoeckius Desirea Mecenas Dominic Grün Guido Mastrobuoni Stefan Kempa Nikolaus Rajewsky

Mol Cell 2011 Dec;44(5):828-40

Systems Biology of Gene Regulatory Elements, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.molcel.2011.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253457PMC
December 2011

Expression of root glutamate dehydrogenase genes in tobacco plants subjected to boron deprivation.

Authors:
Víctor M Beato M Teresa Navarro-Gochicoa Jesús Rexach M Begoña Herrera-Rodríguez Juan J Camacho-Cristóbal Stefan Kempa Wolfram Weckwerth Agustín González-Fontes

Plant Physiol Biochem 2011 Nov 12;49(11):1350-4. Epub 2011 Jun 12.

Departamento de Fisiología, Anatomía y Biología Celular, Universidad Pablo de Olavide, E-41013 Sevilla, Spain.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.plaphy.2011.06.001DOI Listing
November 2011

De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics.

Authors:
Catherine Adamidi Yongbo Wang Dominic Gruen Guido Mastrobuoni Xintian You Dominic Tolle Matthias Dodt Sebastian D Mackowiak Andreas Gogol-Doering Pinar Oenal Agnieszka Rybak Eric Ross Alejandro Sánchez Alvarado Stefan Kempa Christoph Dieterich Nikolaus Rajewsky Wei Chen

Genome Res 2011 Jul 2;21(7):1193-200. Epub 2011 May 2.

Max-Delbrück-Center for Molecular Medicine, Berlin Institute for Medical Systems Biology, Robert Rössle Strasse 10, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1101/gr.113779.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129261PMC
July 2011

Targeted proteomics for Chlamydomonas reinhardtii combined with rapid subcellular protein fractionation, metabolomics and metabolic flux analyses.

Authors:
Stefanie Wienkoop Julia Weiss Patrick May Stefan Kempa Susann Irgang Luis Recuenco-Munoz Matthias Pietzke Thorsten Schwemmer Jens Rupprecht Volker Egelhofer Wolfram Weckwerth

Mol Biosyst 2010 Jun 31;6(6):1018-31. Epub 2010 Mar 31.

Dept. of Molecular Systems Biology, University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1039/b920913aDOI Listing
June 2010

An integrative approach towards completing genome-scale metabolic networks.

Authors:
Nils Christian Patrick May Stefan Kempa Thomas Handorf Oliver Ebenhöh

Mol Biosyst 2009 Dec 10;5(12):1889-903. Epub 2009 Sep 10.

Max-Planck-Institute for Molecular Plant Physiology, Potsdam-Golm, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1039/B915913bDOI Listing
December 2009

Carbon metabolism and bacteroid functioning are involved in the regulation of nitrogen fixation in Medicago truncatula under drought and recovery.

Authors:
Estíbaliz Larrainzar Stefanie Wienkoop Christian Scherling Stefan Kempa Rubén Ladrera Cesar Arrese-Igor Wolfram Weckwerth Esther M González

Mol Plant Microbe Interact 2009 Dec;22(12):1565-76

Departamento Ciencias del Medio Natural, Universidad Pública de Navarra, Pamplona, Spain.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1094/MPMI-22-12-1565DOI Listing
December 2009

ChlamyCyc: an integrative systems biology database and web-portal for Chlamydomonas reinhardtii.

Authors:
Patrick May Jan-Ole Christian Stefan Kempa Dirk Walther

BMC Genomics 2009 May 4;10:209. Epub 2009 May 4.

Max-Planck-Institute of Molecular Plant Physiology, Potsdam, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1186/1471-2164-10-209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688524PMC
May 2009

A central role of abscisic acid in stress-regulated carbohydrate metabolism.

Authors:
Stefan Kempa Julia Krasensky Silvia Dal Santo Joachim Kopka Claudia Jonak

PLoS One 2008 12;3(12):e3935. Epub 2008 Dec 12.

Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Vienna, Austria.

View Article

Download full-text PDF

 Source
http://edoc.mdc-berlin.de/10699/1/10699oa.pdf
Web Search
http://dx.plos.org/10.1371/journal.pone.0003935
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003935PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593778PMC
February 2009

An automated GCxGC-TOF-MS protocol for batch-wise extraction and alignment of mass isotopomer matrixes from differential 13C-labelling experiments: a case study for photoautotrophic-mixotrophic grown Chlamydomonas reinhardtii cells.

Authors:
Stefan Kempa Jan Hummel Thorsten Schwemmer Matthias Pietzke Nadine Strehmel Stefanie Wienkoop Joachim Kopka Wolfram Weckwerth

J Basic Microbiol 2009 Feb;49(1):82-91

GoFORSYS, University of Potsdam, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1002/jobm.200800337DOI Listing
February 2009

Metabolomics- and proteomics-assisted genome annotation and analysis of the draft metabolic network of Chlamydomonas reinhardtii.

Authors:
Patrick May Stefanie Wienkoop Stefan Kempa Björn Usadel Nils Christian Jens Rupprecht Julia Weiss Luis Recuenco-Munoz Oliver Ebenhöh Wolfram Weckwerth Dirk Walther

Genetics 2008 May;179(1):157-66

GoFORSYS, Institute of Biochemistry and Biology, University of Potsdam, 14424 Potsdam-Golm, Germany 0331-5678.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1534/genetics.108.088336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390595PMC
May 2008

A plastid-localized glycogen synthase kinase 3 modulates stress tolerance and carbohydrate metabolism.

Authors:
Stefan Kempa Wilfried Rozhon Jozef Samaj Alexander Erban Frantisek Baluska Thomas Becker Joachim Haselmayer Enrico Schleiff Joachim Kopka Heribert Hirt Claudia Jonak

Plant J 2007 Mar 22;49(6):1076-90. Epub 2007 Feb 22.

Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Vienna Biocenter, A-1030 Vienna, Austria.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1111/j.1365-313X.2006.03025.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865003PMC
March 2007

Towards dissecting nutrient metabolism in plants: a systems biology case study on sulphur metabolism.

Authors:
Victoria J Nikiforova Bertrand Gakière Stefan Kempa Monika Adamik Lothar Willmitzer Holger Hesse Rainer Hoefgen

J Exp Bot 2004 Aug 18;55(404):1861-70. Epub 2004 Jun 18.

Max-Planck-Institut für Molekulare Pflanzenphysiologie, Department of Molecular Physiology, Am Mühlenberg 1, D-14476 Golm, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1093/jxb/erh177DOI Listing
August 2004

Muscle-type creatine kinase interacts with central domains of the M-band proteins myomesin and M-protein.

Authors:
Thorsten Hornemann Stefan Kempa Mirko Himmel Katrin Hayess Dieter O Fürst Theo Wallimann

J Mol Biol 2003 Sep;332(4):877-87

Institute of Cell Biology, Swiss Federal Institute of Technology, CH-8093 Zürich, Switzerland.

View Article

Download full-text PDF

 Source
September 2003

Transcriptome analysis of sulfur depletion in Arabidopsis thaliana: interlacing of biosynthetic pathways provides response specificity.

Authors:
Victoria Nikiforova Jens Freitag Stefan Kempa Monika Adamik Holger Hesse Rainer Hoefgen

Plant J 2003 Feb;33(4):633-50

Department 1 of L. Willmitzer, Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476 Golm, Germany.

View Article

Download full-text PDF

 Source
February 2003