Stefan Costinean

Stefan Costinean

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Stefan Costinean

Stefan Costinean

Publications by authors named "Stefan Costinean"

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43Publications

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Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a.

Cell Rep 2016 05 28;15(6):1190-201. Epub 2016 Apr 28.

Department of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA; Eppley Institute for Research in Cancer and Allied Diseases, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA; Center for Leukemia and Lymphoma Research, University of Nebraska Medical Center, Omaha, NE 68198, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864108PMC
May 2016

miR-15b/16-2 deletion promotes B-cell malignancies.

Proc Natl Acad Sci U S A 2015 Sep 31;112(37):11636-41. Epub 2015 Aug 31.

Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, OH 43210;

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http://dx.doi.org/10.1073/pnas.1514954112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577143PMC
September 2015

Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature.

PLoS Genet 2015 May 28;11(5):e1005238. Epub 2015 May 28.

Columbia Center for Human Development, Division of Pulmonary, Allergy & Critical Care Medicine, Department of Medicine, Columbia University, College of Physicians & Surgeons, New York, New York, United States of America.

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http://escholarship.org/uc/item/6ff4w71x.pdf
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http://dx.plos.org/10.1371/journal.pgen.1005238
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http://dx.doi.org/10.1371/journal.pgen.1005238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447351PMC
May 2015

Regulated Expression of miR-155 is Required for iNKT Cell Development.

Front Immunol 2015 30;6:140. Epub 2015 Mar 30.

Molecular Immunology Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS "Istituto Nazionale dei Tumori" , Milan , Italy.

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http://dx.doi.org/10.3389/fimmu.2015.00140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378312PMC
April 2015

MicroRNA 29 targets nuclear factor-κB-repressing factor and Claudin 1 to increase intestinal permeability.

Gastroenterology 2015 Jan 30;148(1):158-169.e8. Epub 2014 Sep 30.

Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.09.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303568PMC
January 2015

Pluripotent stem cell miRNAs and metastasis in invasive breast cancer.

J Natl Cancer Inst 2014 Dec 11;106(12). Epub 2014 Oct 11.

Department of Molecular Virology, Immunology and Molecular Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH (SV, GN, AD, SC, MiG, RAe, RG, GDL, PG, PD, TW, SEW, FP, NZ, HA, KFH, CMC); Biosystems Analysis, LTTA, Deptartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy, (SV, MES, JM, MaG, MM, CZ, FC, MP, JP, MN); Fate Therapeutics, San Diego, CA (RAb); Department of Chemistry, The Scripps Research Institute, La Jolla, CA (CD); Department of Urology, Thomas Jefferson University, Kimmel Cancer Center, Philadelphia, PA (RB); Comprehensive Cancer Center, The Ohio State University, Columbus, OH (KM); Deptartment of Internal Medicine, James Cancer Hospital and Ohio State University Comprehensive Cancer Center, The Ohio State University (CLS); Division of Pathology, II University of Rome "La Sapienza," Ospedale Santo Andrea, Rome, Italy (AV); Department of Surgery, Thomas Jefferson University Medical College, Philadelphia, PA (ALR).

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http://dx.doi.org/10.1093/jnci/dju324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334797PMC
December 2014

Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation.

Proc Natl Acad Sci U S A 2014 Mar 10;111(12):4536-41. Epub 2014 Mar 10.

Department of Molecular Virology, Immunology and Medical Genetics, Wexner Medical Center and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.

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http://dx.doi.org/10.1073/pnas.1402604111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970505PMC
March 2014

Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure.

Am J Pathol 2013 Dec 8;183(6):1719-1730. Epub 2013 Oct 8.

Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio; Center for Childhood Cancer, Nationwide Children's Hospital, Columbus, Ohio; Department of Pathology, The Ohio State University, Columbus, Ohio; Experimental Therapeutics Program, College of Medicine, The Ohio State University, Columbus, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857547PMC
December 2013

Primary intrathyroidal paraganglioma: histopathology and novel molecular alterations.

Hum Pathol 2012 Dec 15;43(12):2371-5. Epub 2012 Oct 15.

Department of Pathology, The Ohio State University, College of Medicine, Columbus, OH 43210, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S004681771200242
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http://dx.doi.org/10.1016/j.humpath.2012.06.021DOI Listing
December 2012

Stem cell-related markers in primary breast cancers and associated metastatic lesions.

Mod Pathol 2012 Jul 2;25(7):949-55. Epub 2012 Mar 2.

Department of Pathology, Yildirim Beyazit University, Ankara Ataturk Research and Training Hospital, Ankara, Turkey.

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http://dx.doi.org/10.1038/modpathol.2012.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400504PMC
July 2012

miR-155 regulates IFN-γ production in natural killer cells.

Blood 2012 Apr 29;119(15):3478-85. Epub 2012 Feb 29.

Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, OH 43210, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-12-39
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http://dx.doi.org/10.1182/blood-2011-12-398099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325038PMC
April 2012

Common fragile site tumor suppressor genes and corresponding mouse models of cancer.

J Biomed Biotechnol 2011 29;2011:984505. Epub 2010 Dec 29.

Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1155/2011/984505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035048PMC
June 2011

Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer.

Proc Natl Acad Sci U S A 2011 Mar 7;108(12):4908-13. Epub 2011 Mar 7.

Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Medical Center, Columbus, OH 43210, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1101795108
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http://dx.doi.org/10.1073/pnas.1101795108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064319PMC
March 2011

Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression.

Proc Natl Acad Sci U S A 2010 Jul 21;107(27):12210-5. Epub 2010 Jun 21.

Department of Molecular Virology, Ohio State University School of Medicine, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.1007186107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901490PMC
July 2010

Karyotype-specific microRNA signature in chronic lymphocytic leukemia.

Blood 2009 Oct 28;114(18):3872-9. Epub 2009 Aug 28.

Department of Molecular Virology, Immunology, and Medical Genetics and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1182/blood-2009-06-229211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773482PMC
October 2009

MicroRNAs, the immune system and rheumatic disease.

Nat Clin Pract Rheumatol 2008 Oct 26;4(10):534-41. Epub 2008 Aug 26.

Molecular Virology, Immunology and Medical Genetics Department, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1038/ncprheum0885DOI Listing
October 2008

Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.

Eur J Cancer 2008 Jan 26;44(2):318-25. Epub 2007 Dec 26.

Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università degli Studi di Napoli Federico II, via Pansini, 5, 80131, Naples, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S095980490700916
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http://dx.doi.org/10.1016/j.ejca.2007.11.017DOI Listing
January 2008

Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling.

Mol Cancer Res 2007 Sep 17;5(9):957-65. Epub 2007 Aug 17.

Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-07-0211DOI Listing
September 2007

Targeted deletion of Wwox reveals a tumor suppressor function.

Proc Natl Acad Sci U S A 2007 Mar 27;104(10):3949-54. Epub 2007 Feb 27.

Department of Molecular Virology, Immunology, and Medical Genetics, Comprehensive Cancer Center, Ohio State University, 410 West 12th Avenue, Columbus, OH 43210, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0609783104
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http://dx.doi.org/10.1073/pnas.0609783104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820689PMC
March 2007

Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.

Proc Natl Acad Sci U S A 2006 May 25;103(18):7024-9. Epub 2006 Apr 25.

Comprehensive Cancer Center, Ohio State University, 400 West 12th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.0602266103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459012PMC
May 2006

Regulation of cell size and contractile function by AKT in cardiomyocytes.

Ann N Y Acad Sci 2004 May;1015:250-60

Laboratory of Molecular Cardiology, San Raffaele Biomedical Science Park of Rome, Italy.

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http://dx.doi.org/10.1196/annals.1302.021DOI Listing
May 2004

Chemoembolization in the treatment of metastatic ileocolic carcinoid.

Rom J Gastroenterol 2002 Jun;11(2):141-7

Centre of Gastroenterology and Hepatology, Fundeni Clinical Institute, Sos. Fundeni no. 258, 72437 Bucharest, Romania.

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June 2002