Srinivasan Yegnasubramanian

Srinivasan Yegnasubramanian

UNVERIFIED PROFILE

Are you Srinivasan Yegnasubramanian?   Register this Author

Register author
Srinivasan Yegnasubramanian

Srinivasan Yegnasubramanian

Publications by authors named "Srinivasan Yegnasubramanian"

Are you Srinivasan Yegnasubramanian?   Register this Author

100Publications

1659Reads

30Profile Views

Transcriptional profiling identifies novel regulators of macrophage polarization.

PLoS One 2018 7;13(12):e0208602. Epub 2018 Dec 7.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208602PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286176PMC
May 2019

Prostate Cancer Epigenetics: From Basic Mechanisms to Clinical Implications.

Cold Spring Harb Perspect Med 2019 Apr 1;9(4). Epub 2019 Apr 1.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21231.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a030445DOI Listing
April 2019

Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties.

Cancer Cell 2019 Apr 4;35(4):633-648.e7. Epub 2019 Apr 4.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2019.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521721PMC
April 2019

Update on Systemic Prostate Cancer Therapies: Management of Metastatic Castration-resistant Prostate Cancer in the Era of Precision Oncology.

Eur Urol 2019 01 16;75(1):88-99. Epub 2018 Apr 16.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD, USA; Department of Urology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2018.03.028DOI Listing
January 2019

Redox-Responsive Nanoparticle-Mediated Systemic RNAi for Effective Cancer Therapy.

Small 2018 Oct 17;14(41):e1802565. Epub 2018 Sep 17.

Center for Nanomedicine and Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/smll.201802565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286670PMC
October 2018

Characterization of novel cell lines derived from a MYC-driven murine model of lethal metastatic adenocarcinoma of the prostate.

Prostate 2018 09 30;78(13):992-1000. Epub 2018 May 30.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23657DOI Listing
September 2018

Comprehensive Evaluation of Programmed Death-Ligand 1 Expression in Primary and Metastatic Prostate Cancer.

Am J Pathol 2018 06 22;188(6):1478-1485. Epub 2018 Mar 22.

Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland; Department of Pathology, The Johns Hopkins School of Medicine, Baltimore, Maryland; Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, Maryland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029440173117
Publisher Site
http://dx.doi.org/10.1016/j.ajpath.2018.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971230PMC
June 2018

The structure of the nucleus in normal and neoplastic prostate cells: untangling the role of type 2 DNA topoisomerases.

Am J Clin Exp Urol 2018 1;6(2):107-113. Epub 2018 Apr 1.

Sidney Kimmel Comprehensive Cancer Center and Brady Urological Institute, Johns Hopkins University School of MedicineBaltimore, MD 21218, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902729PMC
April 2018

Profiling the Urinary Microbiome in Men with Positive versus Negative Biopsies for Prostate Cancer.

J Urol 2018 01 7;199(1):161-171. Epub 2017 Aug 7.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Sidney Kimmel Comprehensive Cancer Center, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.juro.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937117PMC
January 2018

The inflammatory microenvironment and microbiome in prostate cancer development.

Nat Rev Urol 2018 Jan 31;15(1):11-24. Epub 2017 Oct 31.

Department of Pathology, Johns Hopkins University School of Medicine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrurol.2017.167DOI Listing
January 2018

Androgen Receptor Splice Variants Are Not Substrates of Nonsense-Mediated Decay.

Prostate 2017 Jun 22;77(8):829-837. Epub 2017 Feb 22.

Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400682PMC
June 2017

Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations.

Proc Natl Acad Sci U S A 2017 05 17;114(18):4733-4738. Epub 2017 Apr 17.

Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD 21128;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1701382114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422780PMC
May 2017

c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks.

EBioMedicine 2017 Apr 5;18:83-93. Epub 2017 Apr 5.

Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo, Oslo, Norway; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; PCUK/Movember Centre of Excellence, CCRCB, Queen's University, Belfast, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2017.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405195PMC
April 2017

Prostate cancer epigenetics and its clinical implications.

Asian J Androl 2016 Jul-Aug;18(4):549-58

Sidney Kimmel Comprehensive Cancer Center, Department of Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/1008-682X.179859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955178PMC
March 2017

Inflammation, Microbiota, and Prostate Cancer.

Eur Urol Focus 2016 Oct 28;2(4):374-382. Epub 2016 Aug 28.

Experimental Urology, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.euf.2016.08.010DOI Listing
October 2016

Premalignancy in Prostate Cancer: Rethinking What we Know.

Cancer Prev Res (Phila) 2016 Aug 26;9(8):648-56. Epub 2016 Jan 26.

Departments of Pathology Oncology Urology The Johns Hopkins University School of Medicine, The Sidney Kimmel Comprehensive Cancer Center The Brady Urological Research Institute at Johns Hopkins, Johns Hopkins University, Baltimore, MD.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1940-6207.CAPR-15-0431DOI Listing
August 2016

Simultaneous quantitative determination of 5-aza-2'-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors.

J Chromatogr B Analyt Technol Biomed Life Sci 2016 Jun 21;1022:38-45. Epub 2016 Mar 21.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA; Department of Oncology, School of Medicine, Johns Hopkins University, 1650 Orleans Street, Baltimore, MD, 21231 USA; Division of Clinical Pharmacology, Department of Medicine, School of Medicine, Johns Hopkins University, 1650 Orleans Street, Baltimore, MD, 21231 USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jchromb.2016.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866886PMC
June 2016

Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression.

Cancer Res 2015 Oct 20;75(20):4322-34. Epub 2015 Aug 20.

The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University, Baltimore, Maryland. The Department of Oncology, Johns Hopkins University, Baltimore, Maryland. The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-15-0024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609262PMC
October 2015

Global DNA methylation changes and differential gene expression in Anaplasma phagocytophilum-infected human neutrophils.

Clin Epigenetics 2015 29;7:77. Epub 2015 Jul 29.

Graduate Program in Cellular and Molecular Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD USA ; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD USA ; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD USA ; Department of Microbiology and Immunology, University School of Medicine, Baltimore, MD USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-015-0105-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518890PMC
July 2015

RNA-Seq of the nucleolus reveals abundant SNORD44-derived small RNAs.

PLoS One 2014 9;9(9):e107519. Epub 2014 Sep 9.

Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107519PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159348PMC
May 2015

Should Gleason 6 be labeled as cancer?

Curr Opin Urol 2015 May;25(3):238-45

aDepartment of Pathology bDepartment of Urology cDepartment of Oncology dThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins eThe Brady Urological Research Institute.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOU.0000000000000165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878816PMC
May 2015

Diagnostic challenges of clonal heterogeneity in prostate cancer.

J Clin Oncol 2015 Mar 17;33(7):e38-40. Epub 2014 Mar 17.

Sidney Kimmel Comprehensive Cancer Center; and Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2013.50.3540DOI Listing
March 2015

Prostate adenocarcinomas aberrantly expressing p63 are molecularly distinct from usual-type prostatic adenocarcinomas.

Mod Pathol 2015 Mar 12;28(3):446-56. Epub 2014 Sep 12.

1] Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA [2] Department of Oncology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2014.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344845PMC
March 2015

Epigenetic DNA methylation of antioxidative stress regulator NRF2 in human prostate cancer.

Cancer Prev Res (Phila) 2014 Dec 29;7(12):1186-97. Epub 2014 Sep 29.

Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1940-6207.CAPR-14-0127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256109PMC
December 2014

Time-Resolved Fluorescence Resonance Energy Transfer Assay for Discovery of Small-Molecule Inhibitors of Methyl-CpG Binding Domain Protein 2.

J Biomol Screen 2014 Aug 7;19(7):1060-9. Epub 2014 Mar 7.

Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1087057114526433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183726PMC
August 2014

Preparation of fragment libraries for next-generation sequencing on the applied biosystems SOLiD platform.

Methods Enzymol 2013 ;529:185-200

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-418687-3.00015-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991121PMC
April 2014

Explanatory chapter: next generation sequencing.

Methods Enzymol 2013 ;529:201-8

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-418687-3.00016-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978176PMC
April 2014

The diet as a cause of human prostate cancer.

Cancer Treat Res 2014 ;159:51-68

Departments of Oncology, Pathology, and Urology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Weinberg Bldg 1100, 1650 Orleans Street, Baltimore, MD, 21231, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-642-38007-5_4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486067PMC
April 2014

Telomere phenotypes in females with heterozygous mutations in the dyskeratosis congenita 1 (DKC1) gene.

Hum Mutat 2013 Nov 11;34(11):1481-5. Epub 2013 Sep 11.

Department of Oncology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.22397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926107PMC
November 2013

Regulation of human hematopoietic stem cell self-renewal by the microenvironment's control of retinoic acid signaling.

Proc Natl Acad Sci U S A 2013 Oct 16;110(40):16121-6. Epub 2013 Sep 16.

The Sidney Kimmel Comprehensive Cancer Center, and Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1305937110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791732PMC
October 2013

Resistance emerges to second-generation antiandrogens in prostate cancer.

Cancer Discov 2013 Sep;3(9):971-4

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-13-0405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800038PMC
September 2013

A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes.

Prostate 2013 Jun 6;73(9):1007-15. Epub 2013 Feb 6.

Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.22648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991131PMC
June 2013

Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease.

Cell Cycle 2013 Jun 15;12(12):1835-41. Epub 2013 May 15.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.25010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735697PMC
June 2013

Aiming for the outliers: cancer precision medicine through targeting kinases with extreme expression.

Cancer Discov 2013 Mar;3(3):252-4

Sidney Kimmel Comprehensive Cancer Center, The Sol Golman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, Maryland 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-13-0016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486056PMC
March 2013

Prospective study of genomic hypomethylation of leukocyte DNA and colorectal cancer risk.

Cancer Epidemiol Biomarkers Prev 2012 Nov 20;21(11):2014-21. Epub 2012 Sep 20.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8110, MSC 7240, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1055-9965.EPI-12-0700-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493855PMC
November 2012

A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts.

Nucleic Acids Res 2012 Aug 13;40(14):6821-33. Epub 2012 Apr 13.

The James Buchannan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gks308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413119PMC
August 2012

Global levels of H3K27me3 track with differentiation in vivo and are deregulated by MYC in prostate cancer.

Am J Pathol 2012 Aug 17;181(2):560-9. Epub 2012 Jun 17.

Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2012.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409442PMC
August 2012

USP2a activation of MYC in prostate cancer.

Cancer Discov 2012 Mar;2(3):206-7

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-12-0027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479124PMC
March 2012

Beefing up prostate cancer therapy with performance-enhancing (anti-) steroids.

Cancer Cell 2011 Jul;20(1):7-9

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231-1000, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2011.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479125PMC
July 2011

Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target?

Clin Cancer Res 2011 Jun 8;17(12):3858-64. Epub 2011 Mar 8.

Authors' Affiliation: Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-10-2044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117909PMC
June 2011

Accurate genome-scale percentage DNA methylation estimates from microarray data.

Biostatistics 2011 Apr 21;12(2):197-210. Epub 2010 Sep 21.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University and Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/biostatistics/kxq055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062148PMC
April 2011

Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth.

Prostate 2011 Mar 31;71(4):333-43. Epub 2010 Aug 31.

Chemical Therapeutics Program, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.21247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043358PMC
March 2011

Prostate cancer: New answers prompt new questions regarding cell of origin.

Nat Rev Urol 2010 Dec;7(12):650-2

The Brady Urological Research Institute and The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nrurol.2010.188
Publisher Site
http://dx.doi.org/10.1038/nrurol.2010.188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486068PMC
December 2010

Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth.

Mol Cancer Ther 2010 Feb 2;9(2):336-46. Epub 2010 Feb 2.

Division of Toxicology, Bloomberg School of Public Health, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-09
Publisher Site
http://dx.doi.org/10.1158/1535-7163.MCT-09-0589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821808PMC
February 2010

Epigenetic alterations in human prostate cancers.

Endocrinology 2009 Sep 11;150(9):3991-4002. Epub 2009 Jun 11.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231-1000, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2009-0573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736081PMC
September 2009

miR-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth.

Cancer Res 2009 Sep 8;69(18):7165-9. Epub 2009 Sep 8.

The James Buchanan Brady Urological Institute, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-09-1448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861586PMC
September 2009

Anti-inflammatory drugs, antioxidants, and prostate cancer prevention.

Curr Opin Pharmacol 2009 Aug 1;9(4):419-26. Epub 2009 Jul 1.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coph.2009.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479123PMC
August 2009

Genetic and epigenetic inactivation of LPL gene in human prostate cancer.

Int J Cancer 2009 Feb;124(3):734-8

Center for Cancer Genomics, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.23972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667349PMC
February 2009

Molecular alterations in prostate cancer as diagnostic, prognostic, and therapeutic targets.

Adv Anat Pathol 2008 Nov;15(6):319-31

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAP.0b013e31818a5c19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214657PMC
November 2008

Stable knockdown of PASG enhances DNA demethylation but does not accelerate cellular senescence in TIG-7 human fibroblasts.

Epigenetics 2008 Sep 3;3(5):281-91. Epub 2008 Sep 3.

Department of Environmental Biochemistry, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba, Japan.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746857PMC
http://dx.doi.org/10.4161/epi.3.5.6914DOI Listing
September 2008

Prognostic value of preoperative serum cell-free circulating DNA in men with prostate cancer undergoing radical prostatectomy.

Clin Cancer Res 2007 Sep;13(18 Pt 1):5361-7

The James Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-06-2781DOI Listing
September 2007

Abnormal DNA methylation, epigenetics, and prostate cancer.

Front Biosci 2007 May 1;12:4254-66. Epub 2007 May 1.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Brady Urological Institute, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
May 2007

Combination of methylated-DNA precipitation and methylation-sensitive restriction enzymes (COMPARE-MS) for the rapid, sensitive and quantitative detection of DNA methylation.

Nucleic Acids Res 2006 Feb 9;34(3):e19. Epub 2006 Feb 9.

Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine 1650 Orleans Street, CRB 116, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gnj022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363782PMC
February 2006