Publications by authors named "Sridhar Sundaram"

34 Publications

Trainee involvement in ERCP: new criteria to simplify a complex problem.

Endoscopy 2021 12 24;53(12):1288. Epub 2021 Nov 24.

Department of Gastroenterology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1055/a-1577-3004DOI Listing
December 2021

Screening for Esophageal Adenocarcinoma: Should We Use Barrett's Screening Protocols?

Clin Gastroenterol Hepatol 2021 Nov 16. Epub 2021 Nov 16.

Department of Digestive Diseases and Clinical Nutrition, TATA Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1016/j.cgh.2021.11.015DOI Listing
November 2021

Does timing of endoscopy matter for acute upper gastrointestinal bleeding in pediatric portal hypertension?

Dig Liver Dis 2022 Jan 12;54(1):144-145. Epub 2021 Nov 12.

Department of Digestive Diseases and Clinical Nutrition, TATA Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1016/j.dld.2021.10.008DOI Listing
January 2022

Decompensation in Patients With Advanced NAFLD: More Questions That Need Answering.

Clin Gastroenterol Hepatol 2021 Nov 6. Epub 2021 Nov 6.

Department of Digestive Diseases and Clinical Nutrition, TATA Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1016/j.cgh.2021.10.043DOI Listing
November 2021

Immunotherapy related colitis.

Indian J Pathol Microbiol 2021 Oct-Dec;64(4):857-859

Department of Pathology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

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http://dx.doi.org/10.4103/ijpm.ijpm_477_21DOI Listing
October 2021

Endoscopic management of postesophagectomy leak with modified clip-and-loop technique.

Endoscopy 2021 Oct 8. Epub 2021 Oct 8.

Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1055/a-1638-8657DOI Listing
October 2021

Endoscopic management of colocolic intussusception in an adult with colonic stent placement.

Endoscopy 2021 Sep 27. Epub 2021 Sep 27.

Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1055/a-1625-5105DOI Listing
September 2021

Conventional EMR vs Underwater EMR: Is the choice straightforward?

Authors:
Sridhar Sundaram

Gastroenterology 2021 Aug 24. Epub 2021 Aug 24.

Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Mumbai.

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http://dx.doi.org/10.1053/j.gastro.2021.08.034DOI Listing
August 2021

Transpancreatic biliary sphincterotomy: justified or overkill?

Endoscopy 2021 09 26;53(9):985. Epub 2021 Aug 26.

Asian Institute of Gastroenterology, Hyderabad, India.

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http://dx.doi.org/10.1055/a-1408-3258DOI Listing
September 2021

Approach to management of pancreatic strictures: the gastroenterologist's perspective.

Clin J Gastroenterol 2021 Dec 17;14(6):1587-1597. Epub 2021 Aug 17.

Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Dr. E Borges Road, Parel, Mumbai, 400012, India.

Pancreatic strictures represent a complex clinical problem which often requires multidisciplinary management with a team of gastroenterologists, surgeons and radiologists. Dominant strictures are largely due to inflammatory processes of the pancreas like chronic pancreatitis. However, differentiating benign from malignant processes of the pancreas, leading to strictures is imperative and remains a challenge. With advances in endoscopic management, options for therapy include endoscopic retrograde cholangiopancreatography (ERCP), and endoscopic ultrasound-guided pancreatic drainage (EUS-PD) in situations where ERCP is not feasible or fails. However, endoscopic therapy is suited for a select group of patients and surgery remains key to management in many patients. In this narrative review, we look at the gastroenterologist's perspective and approach to pancreatic ductal strictures, including endoscopic and surgical management.
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http://dx.doi.org/10.1007/s12328-021-01503-6DOI Listing
December 2021

Functional Disease, Dysbiosis, and Dyspepsia: How Helpful Is Rifaximin?

Dig Dis Sci 2021 Aug 14. Epub 2021 Aug 14.

Department of Gastroenterology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1007/s10620-021-07155-3DOI Listing
August 2021

Endoscopic ultrasound-guided renal biopsy: an alternative to transjugular renal biopsy in high-risk patients.

Endoscopy 2021 Jul 2. Epub 2021 Jul 2.

Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1055/a-1519-6365DOI Listing
July 2021

EUS-guided biliary drainage for malignant hilar biliary obstruction: A concise review.

Endosc Ultrasound 2021 May-Jun;10(3):154-160

Institute of Digestive and Liver Care, SL Raheja Hospital, Mumbai, Maharashtra, India.

EUS-guided biliary drainage (EUS-BD) has emerged as an alternative to ERCP for distal biliary obstruction in expert hands. Various routes for EUS-guided access in distal biliary obstruction include EUS choledochoduodenostomy, EUS-guided rendezvous, and EUS-antegrade (EUS-AG) stent placement. While percutaneous transhepatic biliary drainage and ERCP are established modalities in management of malignant hilar biliary obstruction, the role of EUS-BD is emerging. Various methods of drainage in hilar obstruction include EUS hepaticogastrostomy, EUS hepaticoduodenostomy, EUS-guided bridging stent placement, and combined ERCP and EUS-guided biliary drainage. In this review, we discuss the role of EUS-BD in malignant hilar biliary obstruction with the currently available evidence, along with the limitations and challenges to the use of this modality in management of these patients.
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http://dx.doi.org/10.4103/EUS-D-21-00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248311PMC
June 2021

Post-operative Ascites After Hepatectomy-Not More Than What Meets the Eyes.

J Gastrointest Surg 2021 07 15;25(7):1923-1924. Epub 2021 Jun 15.

Hepatobiliary Division of Department of Surgical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, 400012, India.

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http://dx.doi.org/10.1007/s11605-021-05051-9DOI Listing
July 2021

Outcomes of Dilation of Recalcitrant Pancreatic Strictures Using a Wire-Guided Cystotome.

Clin Endosc 2021 Nov 4;54(6):903-908. Epub 2021 Mar 4.

Department of Gastroenterology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, India.

Background/aims: Pancreatic strictures in chronic pancreatitis are treated using endoscopic retrograde cholangiopancreatography (ERCP) with plastic stent placement. The management of recalcitrant strictures remains a challenge, with the use of a Soehendra stent retriever or a needle knife described in case reports. Here, we discuss our experience with dilation of dominant pancreatic strictures with a 6-Fr cystotome.

Methods: A retrospective review of an endoscopy database was performed to search for patients with pancreatic strictures recalcitrant to conventional methods of dilation in which a cystotome was used. Technical success was defined as the successful dilation of the stricture with plastic stent placement. Functional success was defined as substantial pain relief or resolution of pancreatic fistulae.

Results: Ten patients (mean age, 30.8 years) underwent dilation of a dominant pancreatic stricture secondary to chronic pancreatitis, with a 6-Fr cystotome. Seven patients presented with pain. Three patients had pancreatic fistulae (two had pancreatic ascites and one had a pancreaticopleural fistula). The median stricture length was 10 mm (range, 5-25 mm). The head of the pancreas was the most common location of the stricture (60%). Technical and functional success was achieved in all patients. One patient had self-limiting bleeding, whereas another patient developed mild post-ERCP pancreatitis.

Conclusion: The use of a 6-Fr cystotome (diathermy catheter) can be an alternative method for dilation of recalcitrant pancreatic strictures after the failure of conventional modalities.
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http://dx.doi.org/10.5946/ce.2020.297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652154PMC
November 2021

Hepatitis C: A Tale of Three Nobel Laureates and the Ladder to Elimination.

J Assoc Physicians India 2020 Dec;68(12):14-15

Professor and Head, Department of Gastroenterology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra.

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December 2020

Therapeutic misadventure after use of cardiac septal occluder in an esophagopleural fistula.

Gastrointest Endosc 2021 Mar 10;93(3):762-764. Epub 2020 Sep 10.

Department of Gastroenterology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1016/j.gie.2020.09.003DOI Listing
March 2021

Outcomes of Endoscopic Management among Patients with Bile Leak of Various Etiologies at a Tertiary Care Center.

Clin Endosc 2020 Nov 21;53(6):727-734. Epub 2020 Aug 21.

Department of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, India.

Background/aims: Bile leak is a common complication of cholecystectomy, and it is also observed in other conditions such as ruptured liver abscess, hydatid cyst, and trauma. Endoscopic retrograde cholangiopancreatography (ERCP) is the first-line management for such conditions. However, studies on the outcomes of endoscopic management for bile leaks with etiologies other than post-cholecystectomy injury are extremely limited.

Methods: We conducted a retrospective review of patients with symptomatic bile leak who were referred to a tertiary care center and who underwent ERCP between April 2016 and April 2019. The primary outcome was complete symptomatic resolution without extravasation of the contrast medium during the second ERCP conducted after 6 weeks.

Results: In total, 71 patients presented with symptomatic bile leak. The etiologies of bile leak were post-cholecystectomy injury in 34 (47.8%), liver abscess in 20 (28.1%), and post-hydatid cyst surgery in 11 (15.4%) patients. All patients were managed with ERCP, sphincterotomy, and stent placement for 6 weeks, except for one who underwent surgery. The primary outcome was achieved in 65 (91.5%) of 71 patients. There was no significant difference in terms of outcome in relation to the interval between the diagnosis of bile leak and ERCP.

Conclusion: Most patients with bile leak can be successfully managed with ERCP even when performed on an elective basis.
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http://dx.doi.org/10.5946/ce.2020.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719417PMC
November 2020

A survey of clinical practices among oncologists regarding hepatitis B screening in patients with cancer.

Indian J Med Res 2020 06;151(6):604-608

Department of Digestive Diseases & Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

Background & Objectives: Screening for hepatitis B prior to the initiation of chemotherapy in patients with cancer is recommended by all major hepatology and oncology societies. This study was aimed to determine the screening practices for hepatitis B among oncologists from India and their experience with hepatitis B reactivation.

Methods: A questionnaire-based survey was conducted among oncologists attending the Evidence-Based Medicine Conference at Tata Memorial Centre, Mumbai, India. The questionnaire was developed in keeping with the recent guidelines for hepatitis B reactivation on chemotherapy, with questions regarding demographics, years in practice and hepatitis B screening practices and management. There was 78 per cent response rate to the questionnaire.

Results: Most respondents were <35 yr of age (69%), with < five years of experience (39%), practicing in an academic institution (81%). Seventy four per cent respondents always screened their patients with cancer for hepatitis prior to chemotherapy, whereas 19 per cent in special settings and seven per cent never screened; 96 per cent respondents used hepatitis B surface antigen (HBsAg) as a screening test, while 17 per cent also used antibody to hepatitis B core antigen. Sixty one per cent respondents used entecavir or tenofovir for prophylaxis; 70 per cent continued prophylaxis till 6-12 months after completion of chemotherapy, while 21 per cent continued only till the end of chemotherapy.

Interpretation & Conclusions: More than 25 per cent of the oncologists were not screening their patients with cancer for viral hepatitis prior to cancer-directed therapy, and only 17 per cent of the oncologists used the recommended tests for screening. Better training of oncologists regarding viral hepatitis screening and management is needed.
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http://dx.doi.org/10.4103/ijmr.IJMR_2327_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602929PMC
June 2020

How much ARMS twisting is needed to treat GERD?

Authors:
Sridhar Sundaram

Dig Endosc 2021 Mar 22;33(3):464. Epub 2020 Jul 22.

Department of Gastroenterology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.1111/den.13758DOI Listing
March 2021

COVID-19 testing before every endoscopy: Is India ready for prime time?

Authors:
Sridhar Sundaram

Gastrointest Endosc 2020 09 19;92(3):789-791. Epub 2020 May 19.

Department of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, India.

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http://dx.doi.org/10.1016/j.gie.2020.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235597PMC
September 2020

Von Hippel-Lindau Disease Presenting as Obstructive Jaundice.

ACG Case Rep J 2020 Feb 19;7(2):e00324. Epub 2020 Feb 19.

Department of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.

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http://dx.doi.org/10.14309/crj.0000000000000324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145179PMC
February 2020

Necrotizing pancreatitis after removal of prophylactically placed pancreatic stent.

Authors:
Sridhar Sundaram

Turk J Gastroenterol 2019 11;30(11):991-992

Department of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, India.

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http://dx.doi.org/10.5152/tjg.2018.18957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883989PMC
November 2019

Necrotizing pancreatitis after removal of prophylactically placed pancreatic stent.

Authors:
Sridhar Sundaram

Turk J Gastroenterol 2019 10;30(10):928-929

Department of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, India.

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http://dx.doi.org/10.5152/tjg.2018.18914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812959PMC
October 2019

Gastric Amyloidosis Causing Nonvariceal Upper Gastrointestinal Bleeding.

ACG Case Rep J 2019 May 3;6(5):3-4. Epub 2019 May 3.

Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Mumbai, India.

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http://dx.doi.org/10.14309/crj.0000000000000066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650013PMC
May 2019

Amoebic Liver Abscess with Synchronous Colitis: Lessons Learnt in Recent Times.

J Assoc Physicians India 2019 Mar;67(3):11-12

Assistant Professor, Department of Gastroenterology Seth G S Medical College and K E M Hospital Mumbai, Maharashtra.

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March 2019

Overlap Syndrome between Primary Biliary Cholangitis and Primary Sclerosing Cholangitis.

ACG Case Rep J 2018 18;5:e54. Epub 2018 Jul 18.

Department of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, India.

Overlap syndrome indicates the coexistence of 2 or more autoimmune liver diseases in the same individual, occurring simultaneously or sequentially. Cases of overlap of autoimmune hepatitis (AIH) with primary biliary cholangitis (PBC) and of AIH with primary sclerosing cholangitis (PSC) are known and have defined criteria for diagnosis. Overlap between PBC and PSC has been reported in only a few case reports. The cause for the rarity of this entity compared to other overlap syndromes is unclear. We present a case of an overlap syndrome of PBC with PSC in a 35-year-old woman.
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http://dx.doi.org/10.14309/crj.2018.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053546PMC
July 2018

A rare case of metastatic germ cell tumor to stomach and duodenum masquerading as signet ring cell adenocarcinoma.

Ann Transl Med 2016 Aug;4(16):309

Tata Medical Centre, Mumbai, Maharashtra, India.

Adenocarcinomas are the most common cancers affecting stomach. However gastrointestinal stromal tumors (GIST), lymphomas and neuroendocrine tumors (NETs) can also affect the stomach. But stomach is relatively rare site of involvement by metastasis. In this case report a rare metastasis of germ cell tumor (GCT) into stomach is described which clinically and endoscopically masquerade as primary gastric cancers. But detailed clinical examination and vigilant histopathological reporting proves the origin of tumor distant from stomach and thereby change the whole approach of management.
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http://dx.doi.org/10.21037/atm.2016.08.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009030PMC
August 2016

Leprous polyneuritis cranialis mimicking orbital apex syndrome.

J Assoc Physicians India 2014 Aug;62(8):747-9

Leprosy is one of the most prevalent infections in India, with our country accounting for almost 60 percent of the world's patients. Hence unusual presentations of leprosy should be sought for and treated at the earliest. We report this rare case of polyneuritis cranialis secondary to leprosy. Affection ofa single cranial nerve has been described previously but there is only one report of leprosy presenting like orbital apex syndrome.
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August 2014
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