Publications by authors named "Sreerama Shetty"

51Publications

HDAC6 inhibition blocks inflammatory signaling and caspase-1 activation in LPS-induced acute lung injury.

Toxicol Appl Pharmacol 2019 05 22;370:178-183. Epub 2019 Mar 22.

Center for Research on Environmental Disease, University of Kentucky, Lexington, KY, USA; Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY, USA.

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May 2019

p53 Expression in Lung Fibroblasts Is Linked to Mitigation of Fibrotic Lung Remodeling.

Am J Pathol 2018 10;188(10):2207-2222

Texas Lung Injury Institute, Department of Medicine, University of Texas Health Science Center at Tyler, Tyler, Texas. Electronic address:

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October 2018

Fibrin turnover and pleural organization: bench to bedside.

Am J Physiol Lung Cell Mol Physiol 2018 05 18;314(5):L757-L768. Epub 2018 Jan 18.

Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler , Tyler, Texas.

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May 2018

Formulation for a novel inhaled peptide therapeutic for idiopathic pulmonary fibrosis.

Drug Dev Ind Pharm 2018 Feb 10;44(2):184-198. Epub 2017 Nov 10.

a Division of Pharmaceutics , College of Pharmacy, The University of Texas at Austin , Austin , TX , USA.

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February 2018

Regulation of p53-mediated changes in the uPA-fibrinolytic system and in lung injury by loss of surfactant protein C expression in alveolar epithelial cells.

Am J Physiol Lung Cell Mol Physiol 2017 06 6;312(6):L783-L796. Epub 2017 Apr 6.

Texas Lung Injury Institute, University of Texas Health Science Center at Tyler, Tyler, Texas; and

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June 2017

p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis.

Am J Pathol 2017 May 6;187(5):1016-1034. Epub 2017 Mar 6.

Department of Medicine, Texas Lung Injury Institute, University of Texas Health Science Center at Tyler, Tyler, Texas. Electronic address:

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May 2017

Dasatinib-loaded albumin nanoparticles possess diminished endothelial cell barrier disruption and retain potent anti-leukemia cell activity.

Oncotarget 2016 Aug;7(31):49699-49709

Center for Research on Environmental Disease, College of Medicine, University of Kentucky, Lexington, KY, USA.

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August 2016

Selective HDAC6 inhibition prevents TNF-α-induced lung endothelial cell barrier disruption and endotoxin-induced pulmonary edema.

Am J Physiol Lung Cell Mol Physiol 2016 07 17;311(1):L39-47. Epub 2016 May 17.

Center for Research on Environmental Disease, College of Medicine, University of Kentucky, Lexington, Kentucky; Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, Kentucky; and

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July 2016

p53- and PAI-1-mediated induction of C-X-C chemokines and CXCR2: importance in pulmonary inflammation due to cigarette smoke exposure.

Am J Physiol Lung Cell Mol Physiol 2016 Mar 8;310(6):L496-506. Epub 2016 Jan 8.

The Texas Lung Injury Institute, The University of Texas Health Science Center at Tyler, Tyler, Texas; and

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March 2016

Deletion of Src family kinase Lyn aggravates endotoxin-induced lung inflammation.

Am J Physiol Lung Cell Mol Physiol 2015 Dec 9;309(11):L1376-81. Epub 2015 Oct 9.

Center for Research on Environmental Disease, University of Kentucky, Lexington, Kentucky; Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky;

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December 2015

Plasminogen activator inhibitor-1 in cigarette smoke exposure and influenza A virus infection-induced lung injury.

PLoS One 2015 1;10(5):e0123187. Epub 2015 May 1.

Texas Lung Injury Institute, Department of Medicine, University of Texas Health Science Center at Tyler, Tyler, Texas, United States of America.

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January 2016

Sirt1 restrains lung inflammasome activation in a murine model of sepsis.

Am J Physiol Lung Cell Mol Physiol 2015 Apr 6;308(8):L847-53. Epub 2015 Feb 6.

Center for Research on Environmental Disease, University of Kentucky, Lexington, Kentucky; Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky;

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April 2015

Role of p53-fibrinolytic system cross-talk in the regulation of quartz-induced lung injury.

Toxicol Appl Pharmacol 2015 Mar 14;283(2):92-8. Epub 2015 Jan 14.

Texas Lung Injury Institute, Department of Medicine, University of Texas Health Science Center at Tyler, 11937 US Highway 271, Tyler, TX 75708, USA. Electronic address:

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March 2015

Role of the urokinase-fibrinolytic system in epithelial-mesenchymal transition during lung injury.

Am J Pathol 2015 Jan 3;185(1):55-68. Epub 2014 Nov 3.

Department of Medicine, Texas Lung Injury Institute, University of Texas Health Science Center at Tyler, Tyler, Texas. Electronic address:

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January 2015

Regulation of epithelial sodium channels in urokinase plasminogen activator deficiency.

Am J Physiol Lung Cell Mol Physiol 2014 Oct 29;307(8):L609-17. Epub 2014 Aug 29.

Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, Texas; Texas Lung Injury Institute, The University of Texas Health Science Center at Tyler, Tyler, Texas; and

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October 2014

Sirt1 deletion leads to enhanced inflammation and aggravates endotoxin-induced acute kidney injury.

PLoS One 2014 4;9(6):e98909. Epub 2014 Jun 4.

Center for Research on Environmental Disease, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America; Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America.

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August 2015