Soren K Thomsen

Soren K Thomsen

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Soren K Thomsen

Soren K Thomsen

Publications by authors named "Soren K Thomsen"

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Prioritising Causal Genes at Type 2 Diabetes Risk Loci.

Curr Diab Rep 2017 Sep;17(9):76

Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, UK.

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http://link.springer.com/10.1007/s11892-017-0907-y
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http://dx.doi.org/10.1007/s11892-017-0907-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534459PMC
September 2017

Human genetics as a model for target validation: finding new therapies for diabetes.

Diabetologia 2017 06 26;60(6):960-970. Epub 2017 Apr 26.

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Old Road, Headington, Oxford, OX3 7LE, UK.

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http://link.springer.com/10.1007/s00125-017-4270-y
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http://dx.doi.org/10.1007/s00125-017-4270-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423999PMC
June 2017

Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants.

Diabetes 2016 Dec 23;65(12):3805-3811. Epub 2016 Aug 23.

Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.

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http://diabetes.diabetesjournals.org/content/diabetes/early/
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http://dx.doi.org/10.2337/db16-0361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402869PMC
December 2016

The Importance of Context: Uncovering Species- and Tissue-Specific Effects of Genetic Risk Variants for Type 2 Diabetes.

Front Endocrinol (Lausanne) 2016 31;7:112. Epub 2016 Aug 31.

Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, UK; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, UK.

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http://dx.doi.org/10.3389/fendo.2016.00112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005446PMC
September 2016

Loss-of-Function Mutations in the Cell-Cycle Control Gene CDKN2A Impact on Glucose Homeostasis in Humans.

Diabetes 2016 Feb 5;65(2):527-33. Epub 2015 Nov 5.

Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, U.K. Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, U.K.

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http://dx.doi.org/10.2337/db15-0602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724950PMC
February 2016

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

Authors:
Kyle J Gaulton Teresa Ferreira Yeji Lee Anne Raimondo Reedik Mägi Michael E Reschen Anubha Mahajan Adam Locke N William Rayner Neil Robertson Robert A Scott Inga Prokopenko Laura J Scott Todd Green Thomas Sparso Dorothee Thuillier Loic Yengo Harald Grallert Simone Wahl Mattias Frånberg Rona J Strawbridge Hans Kestler Himanshu Chheda Lewin Eisele Stefan Gustafsson Valgerdur Steinthorsdottir Gudmar Thorleifsson Lu Qi Lennart C Karssen Elisabeth M van Leeuwen Sara M Willems Man Li Han Chen Christian Fuchsberger Phoenix Kwan Clement Ma Michael Linderman Yingchang Lu Soren K Thomsen Jana K Rundle Nicola L Beer Martijn van de Bunt Anil Chalisey Hyun Min Kang Benjamin F Voight Gonçalo R Abecasis Peter Almgren Damiano Baldassarre Beverley Balkau Rafn Benediktsson Matthias Blüher Heiner Boeing Lori L Bonnycastle Erwin P Bottinger Noël P Burtt Jason Carey Guillaume Charpentier Peter S Chines Marilyn C Cornelis David J Couper Andrew T Crenshaw Rob M van Dam Alex S F Doney Mozhgan Dorkhan Sarah Edkins Johan G Eriksson Tonu Esko Elodie Eury João Fadista Jason Flannick Pierre Fontanillas Caroline Fox Paul W Franks Karl Gertow Christian Gieger Bruna Gigante Omri Gottesman George B Grant Niels Grarup Christopher J Groves Maija Hassinen Christian T Have Christian Herder Oddgeir L Holmen Astradur B Hreidarsson Steve E Humphries David J Hunter Anne U Jackson Anna Jonsson Marit E Jørgensen Torben Jørgensen Wen-Hong L Kao Nicola D Kerrison Leena Kinnunen Norman Klopp Augustine Kong Peter Kovacs Peter Kraft Jasmina Kravic Cordelia Langford Karin Leander Liming Liang Peter Lichtner Cecilia M Lindgren Eero Lindholm Allan Linneberg Ching-Ti Liu Stéphane Lobbens Jian'an Luan Valeriya Lyssenko Satu Männistö Olga McLeod Julia Meyer Evelin Mihailov Ghazala Mirza Thomas W Mühleisen Martina Müller-Nurasyid Carmen Navarro Markus M Nöthen Nikolay N Oskolkov Katharine R Owen Domenico Palli Sonali Pechlivanis Leena Peltonen John R B Perry Carl G P Platou Michael Roden Douglas Ruderfer Denis Rybin Yvonne T van der Schouw Bengt Sennblad Gunnar Sigurðsson Alena Stančáková Gerald Steinbach Petter Storm Konstantin Strauch Heather M Stringham Qi Sun Barbara Thorand Emmi Tikkanen Anke Tonjes Joseph Trakalo Elena Tremoli Tiinamaija Tuomi Roman Wennauer Steven Wiltshire Andrew R Wood Eleftheria Zeggini Ian Dunham Ewan Birney Lorenzo Pasquali Jorge Ferrer Ruth J F Loos Josée Dupuis Jose C Florez Eric Boerwinkle James S Pankow Cornelia van Duijn Eric Sijbrands James B Meigs Frank B Hu Unnur Thorsteinsdottir Kari Stefansson Timo A Lakka Rainer Rauramaa Michael Stumvoll Nancy L Pedersen Lars Lind Sirkka M Keinanen-Kiukaanniemi Eeva Korpi-Hyövälti Timo E Saaristo Juha Saltevo Johanna Kuusisto Markku Laakso Andres Metspalu Raimund Erbel Karl-Heinz Jöcke Susanne Moebus Samuli Ripatti Veikko Salomaa Erik Ingelsson Bernhard O Boehm Richard N Bergman Francis S Collins Karen L Mohlke Heikki Koistinen Jaakko Tuomilehto Kristian Hveem Inger Njølstad Panagiotis Deloukas Peter J Donnelly Timothy M Frayling Andrew T Hattersley Ulf de Faire Anders Hamsten Thomas Illig Annette Peters Stephane Cauchi Rob Sladek Philippe Froguel Torben Hansen Oluf Pedersen Andrew D Morris Collin N A Palmer Sekar Kathiresan Olle Melander Peter M Nilsson Leif C Groop Inês Barroso Claudia Langenberg Nicholas J Wareham Christopher A O'Callaghan Anna L Gloyn David Altshuler Michael Boehnke Tanya M Teslovich Mark I McCarthy Andrew P Morris

Nat Genet 2015 Dec 9;47(12):1415-25. Epub 2015 Nov 9.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666734PMC
December 2015

Keys to the kingdom.

Nat Biotechnol 2015 Mar 26;33(3):232-6. Epub 2015 Feb 26.

1] Oxbridge Biotech Roundtable, London, UK. [2] Department of Biochemistry, Glycobiology Institute, University of Oxford, UK.

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http://dx.doi.org/10.1038/nbt.3159DOI Listing
March 2015

Phenotypic severity of homozygous GCK mutations causing neonatal or childhood-onset diabetes is primarily mediated through effects on protein stability.

Hum Mol Genet 2014 Dec 11;23(24):6432-40. Epub 2014 Jul 11.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK, Molecular Genetics Laboratory, Royal Devon and Exeter NHS Foundation Trust, Exeter EX2 5DW, UK.

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http://dx.doi.org/10.1093/hmg/ddu360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240195PMC
December 2014

The pancreatic β cell: recent insights from human genetics.

Trends Endocrinol Metab 2014 Aug 28;25(8):425-34. Epub 2014 Jun 28.

Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Headington, OX3 7LE, UK; Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Headington, OX3 7LE, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10432760140008
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http://dx.doi.org/10.1016/j.tem.2014.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229643PMC
August 2014