Soren Germer

Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) program.

PLoS One 2020 25;15(11):e0242364. Epub 2020 Nov 25.

Center for Individualized and Genomic Medicine Research (CIGMA), Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan, United States of America.

View Article and Find Full Text PDF

January 2021

Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium.

Nat Commun 2020 10 12;11(1):5139. Epub 2020 Oct 12.

Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.

View Article and Find Full Text PDF

October 2020

Mapping the 17q12-21.1 Locus for Variants Associated with Early-onset Asthma in African Americans.

Am J Respir Crit Care Med 2020 Sep 23. Epub 2020 Sep 23.

Henry Ford Health System, 2971, Center for Individualized and Genomic Medicine Research (CIGMA), Detroit, Michigan, United States;

View Article and Find Full Text PDF

September 2020

Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium.

bioRxiv 2020 Apr 10. Epub 2020 Apr 10.

Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA.

View Article and Find Full Text PDF

April 2020

Whole-Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth.

Am J Respir Crit Care Med 2020 10;202(7):962-972

Department of Bioengineering and Therapeutic Sciences and.

View Article and Find Full Text PDF

October 2020

Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand and Gene-By-Air-Pollution Interaction.

Genetics 2020 Jul 23;215(3):869-886. Epub 2020 Apr 23.

Department of Medicine, University of California, San Francisco, California 94143.

View Article and Find Full Text PDF

July 2020

Deep whole-genome sequencing of 3 cancer cell lines on 2 sequencing platforms.

Authors:

Kanika Arora Minita Shah Molly Johnson Rashesh Sanghvi Jennifer Shelton Kshithija Nagulapalli Dayna M Oschwald Michael C Zody Soren Germer Vaidehi Jobanputra Jade Carter Nicolas Robine

Sci Rep 2019 12 13;9(1):19123. Epub 2019 Dec 13.

New York Genome Center, New York, NY, 10013, USA.

View Article and Find Full Text PDF

December 2019

Whole-genome bisulfite sequencing with improved accuracy and cost.

Authors:

Masako Suzuki Will Liao Frank Wos Andrew D Johnston Justin DeGrazia Jennifer Ishii Toby Bloom Michael C Zody Soren Germer John M Greally

Genome Res 2018 09 9;28(9):1364-1371. Epub 2018 Aug 9.

Center for Epigenomics and Department of Genetics, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

View Article and Find Full Text PDF

September 2018

amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.

Proc Natl Acad Sci U S A 2018 06 6;115(26):E6030-E6038. Epub 2018 Jun 6.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065;

View Article and Find Full Text PDF

June 2018

Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.

Authors:

Angel C Y Mak Marquitta J White Walter L Eckalbar Zachary A Szpiech Sam S Oh Maria Pino-Yanes Donglei Hu Pagé Goddard Scott Huntsman Joshua Galanter Ann Chen Wu Blanca E Himes Soren Germer Julia M Vogel Karen L Bunting Celeste Eng Sandra Salazar Kevin L Keys Jennifer Liberto Thomas J Nuckton Thomas A Nguyen Dara G Torgerson Pui-Yan Kwok Albert M Levin Juan C Celedón Erick Forno Hakon Hakonarson Patrick M Sleiman Amber Dahlin Kelan G Tantisira Scott T Weiss Denise Serebrisky Emerita Brigino-Buenaventura Harold J Farber Kelley Meade Michael A Lenoir Pedro C Avila Saunak Sen Shannon M Thyne William Rodriguez-Cintron Cheryl A Winkler Andrés Moreno-Estrada Karla Sandoval Jose R Rodriguez-Santana Rajesh Kumar L Keoki Williams Nadav Ahituv Elad Ziv Max A Seibold Robert B Darnell Noah Zaitlen Ryan D Hernandez Esteban G Burchard

Am J Respir Crit Care Med 2018 06;197(12):1552-1564

1 Department of Medicine.

View Article and Find Full Text PDF

June 2018

Differential burden of rare protein truncating variants in Alzheimer's disease patients compared to centenarians.

Authors:

Yun Freudenberg-Hua Wentian Li Avinash Abhyankar Vladimir Vacic Vanessa Cortes Danny Ben-Avraham Jeremy Koppel Blaine Greenwald Soren Germer Robert B Darnell Nir Barzilai Jan Freudenberg Gil Atzmon Peter Davies

Hum Mol Genet 2016 07 3;25(14):3096-3105. Epub 2016 Jun 3.

Litwin-Zucker Research Center for the Study of Alzheimer's Disease, The Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY 11030, USA.

View Article and Find Full Text PDF

July 2016

Features of Circulating Parainfluenza Virus Required for Growth in Human Airway.

Authors:

Laura M Palermo Manik Uppal Lucy Skrabanek Paul Zumbo Soren Germer Nora C Toussaint Bert K Rima Devra Huey Stefan Niewiesk Matteo Porotto Anne Moscona

mBio 2016 Mar 15;7(2):e00235. Epub 2016 Mar 15.

Departments of Pediatrics, Microbiology and Immunology, and Physiology and Cellular Biophysics, Columbia University Medical Center, New York, New York, USA

View Article and Find Full Text PDF

March 2016

Disease variants in genomes of 44 centenarians.

Authors:

Yun Freudenberg-Hua Jan Freudenberg Vladimir Vacic Avinash Abhyankar Anne-Katrin Emde Danny Ben-Avraham Nir Barzilai Dayna Oschwald Erika Christen Jeremy Koppel Blaine Greenwald Robert B Darnell Soren Germer Gil Atzmon Peter Davies

Mol Genet Genomic Med 2014 Sep 15;2(5):438-50. Epub 2014 Jun 15.

The Litwin-Zucker Research Center for the Study of Alzheimer's Disease and Memory Disorders, The Feinstein Institute for Medical Research, North Shore-LIJ Manhasset, New York, 11030.

View Article and Find Full Text PDF

September 2014