Publications by authors named "Sophie Rutschmann"

25Publications

T cell metabolism. The protein LEM promotes CD8⁺ T cell immunity through effects on mitochondrial respiration.

Science 2015 05 16;348(6238):995-1001. Epub 2015 Apr 16.

Section of Immunobiology, Division of Inflammation and Immunology, Department of Medicine, Faculty of Medicine, Imperial College London, Exhibition Road, London SW7 2AZ, UK. Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02215, USA.

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May 2015

N-Ethyl-N-nitrosourea mutagenesis in the mouse provides strong genetic and in vivo evidence for the role of the Caspase Recruitment Domain (CARD) of CARD-MAGUK1 in T regulatory cell development.

Immunology 2014 Mar;141(3):446-56

Section of Immunobiology, Division of Immunology and Inflammation, Department of Medicine, Faculty of Medicine, Imperial College London, London, UK.

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March 2014

Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease.

Proc Natl Acad Sci U S A 2012 Aug 6;109(34):13733-8. Epub 2012 Aug 6.

Department of Genetics, The Scripps Research Institute, La Jolla, CA 92037, USA.

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August 2012

Dissecting immunity by germline mutagenesis.

Immunology 2012 Oct;137(2):124-30

National Heart and Lung Institute, Imperial College London, London, UK.

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October 2012

A deficiency in nucleoside salvage impairs murine lymphocyte development, homeostasis, and survival.

J Immunol 2012 Apr 9;188(8):3920-7. Epub 2012 Mar 9.

Section of Immunobiology, Faculty of Medicine, Imperial College London, London W12 0NN, UK.

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April 2012

Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner.

Cell Host Microbe 2011 Mar;9(3):212-222

Department of Immunology and Microbial Sciences, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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March 2011

Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response.

Proc Natl Acad Sci U S A 2009 Mar 6;106(9):3300-5. Epub 2009 Feb 6.

Department of Genetics, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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March 2009

Dissecting innate immunity by germline mutagenesis.

Immunology 2008 Apr 18;123(4):459-68. Epub 2008 Jan 18.

Department of Immunology, Imperial College London, London, UK.

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April 2008

Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes.

Biochem J 2007 Mar;402(2):229-39

Department of Molecular and Experimental Medicine, Division of Biochemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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March 2007

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.

Proc Natl Acad Sci U S A 2006 Jul 10;103(29):10961-6. Epub 2006 Jul 10.

Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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July 2006

Analysis of the MCMV resistome by ENU mutagenesis.

Mamm Genome 2006 May;17(5):398-406

Department of Immunology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA.

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May 2006

Genetic analysis of innate resistance to mouse cytomegalovirus (MCMV).

Brief Funct Genomic Proteomic 2005 Nov;4(3):203-13

The Scripps Research Institute, 10550 N. Torrey Pines Road, IMM-31, La Jolla, CA 92037, USA.

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November 2005

CD36 is a sensor of diacylglycerides.

Nature 2005 Feb;433(7025):523-7

Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA.

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February 2005

Dual activation of the Drosophila toll pathway by two pattern recognition receptors.

Science 2003 Dec;302(5653):2126-30

Unité Propre de Recherche 9022 du CNRS, Institut de Biologie Moléculaire et Cellulaire, 15 rue René Descartes, F67084 Strasbourg Cedex, France.

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December 2003

Cutting edge: the toll pathway is required for resistance to gram-positive bacterial infections in Drosophila.

J Immunol 2002 Feb;168(4):1542-6

Institut de Biologie Moléculaire et Cellulaire, Unité Propre de Recherche 9022 du Centre National de la Recherche Scientifique, Strasbourg, France.

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February 2002