Publications Authored by Sophie Lejeune

MSH2 c.1022T>C, p.Leu341Pro is a founder pathogenic variation and a major cause of Lynch syndrome in the North of France.

Authors:

Catherine Vermaut Julie Leclerc Francis Vasseur Agnes Wacrenier Tonio Lovecchio Denis Boidin Marie-Hélène Rebergue Stéphane Cattan Sylvie Manouvrier Sophie Lejeune Marie-Pierre Buisine

Genes Chromosomes Cancer 2019 Aug 21. Epub 2019 Aug 21.

Department of Biochemistry and Molecular Biology, Inserm UMR-S1172 - Jean-Pierre Aubert Research Center, Lille University, and Lille University Hospital, Lille, France.

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http://dx.doi.org/10.1002/gcc.22804	DOI Listing

August 2019

Calprotectin alone is not sufficient to predict response to methotrexate in early ACR/EULAR 2010 rheumatoid arthritis: Analysis of the ESPOIR cohort.

Authors:

Chloé Bernardy Sophie Lejeune Anaïs Courtier Daniel Wendling Francis Berenbaum Minh Vu Chuong Nguyen Philippe Gaudin Marie Hélène Paclet Athan Baillet

Joint Bone Spine 2019 Jul 17. Epub 2019 Jul 17.

Rheumatology department, hôpital Sud, Grenoble Teaching Hospital, CHU de Grenoble-Alpes, Avenue de Kimberley, BP 338, 38434 Échirolles Cedex, France; University Grenoble-Alpes, GREPI EA7408, 38000 Grenoble, France.

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http://dx.doi.org/10.1016/j.jbspin.2019.07.001	DOI Listing

July 2019

Optimization of Next-Generation Sequencing Technologies for von Hippel Lindau (VHL) Mosaic Mutation Detection and Development of Confirmation Methods.

Authors:

Lucie Coppin Pascal Plouvier Michel Crépin Anne-Sophie Jourdain Emilie Ait Yahya Stéphane Richard Brigitte Bressac-de Paillerets Catherine Cardot-Bauters Sophie Lejeune Julie Leclerc Pascal Pigny

J Mol Diagn 2019 May 5;21(3):462-470. Epub 2019 Feb 5.

UMR-S 1172-Jean-Pierre Aubert Research Center, University of Lille, Lille, France; INSERM, UMR-S 1172, Team on Mucins, Epithelial Differentiation and Carcinogenesis, Lille, France; Department of Biochemistry and Molecular Biology, Centre Hospitalier Régional et Universitaire de Lille, Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2019.01.005	DOI Listing

May 2019

Diversity of genetic events associated with MLH1 promoter methylation in Lynch syndrome families with heritable constitutional epimutation.

Authors:

Julie Leclerc Cathy Flament Tonio Lovecchio Lucie Delattre Emilie Ait Yahya Stéphanie Baert-Desurmont Nelly Burnichon Myriam Bronner Odile Cabaret Sophie Lejeune Rosine Guimbaud Gilles Morin Jacques Mauillon Philippe Jonveaux Pierre Laurent-Puig Thierry Frébourg Nicole Porchet Marie-Pierre Buisine

Genet Med 2018 12 12;20(12):1589-1599. Epub 2018 Apr 12.

Inserm UMR-S 1172, JPA Research Center, Lille University, and Department of Biochemistry and Molecular Biology, Lille University Hospital, Lille, France.

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http://dx.doi.org/10.1038/gim.2018.47	DOI Listing

December 2018

Unusual case of anorexia.

Authors:

Laura Darmaun Estelle Aubry Sophie Lejeune Helene Sudour-Bonnange

BMJ Case Rep 2018 Jun 4;2018. Epub 2018 Jun 4.

Pediatric and AYA oncology Unit, oscar lambret center, lille, France.

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http://dx.doi.org/10.1136/bcr-2017-223739	DOI Listing

June 2018

Morphology and genomic hallmarks of breast tumours developed by ATM deleterious variant carriers.

Breast Cancer Res 2018 04 17;20(1):28. Epub 2018 Apr 17.

INSERM, U900, Paris, France.

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https://breast-cancer-research.biomedcentral.com/articles/10	Publisher Site
http://dx.doi.org/10.1186/s13058-018-0951-9	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905168	PMC

April 2018

Detection of a new heterozygous germline ETV6 mutation in a case with hyperdiploid acute lymphoblastic leukemia.

Authors:

Nicolas Duployez Wadih Abou Chahla Sophie Lejeune Alice Marceau-Renaut Guillaume Letizia Thomas Boyer Sandrine Geffroy Pauline Peyrouze Nathalie Grardel Brigitte Nelken Gérard Michel Yves Bertrand Claude Preudhomme

Eur J Haematol 2018 Jan 9;100(1):104-107. Epub 2017 Nov 9.

Laboratory of Hematology, CHU Lille, Lille, France.

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http://dx.doi.org/10.1111/ejh.12981	DOI Listing

January 2018

Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.

Authors:

Nicolas Duployez Sophie Lejeune Aline Renneville Claude Preudhomme

Expert Rev Hematol 2016 Dec 21;9(12):1189-1202. Epub 2016 Nov 21.

a Laboratory of Hematology , CHU Lille , Lille , France.

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http://dx.doi.org/10.1080/17474086.2016.1257936	DOI Listing

December 2016

Clinical relevance of 8q23, 15q13 and 18q21 SNP genotyping to evaluate colorectal cancer risk.

Authors:

Stéphanie Baert-Desurmont Françoise Charbonnier Estelle Houivet Lorena Ippolito Jacques Mauillon Marion Bougeard Caroline Abadie David Malka Jacqueline Duffour Françoise Desseigne Chrystelle Colas Pascal Pujol Sophie Lejeune Catherine Dugast Bruno Buecher Laurence Faivre Dominique Leroux Paul Gesta Isabelle Coupier Rosine Guimbaud Pascaline Berthet Sylvie Manouvrier Estelle Cauchin Fabienne Prieur Pierre Laurent-Puig Marine Lebrun Philippe Jonveaux Jean Chiesa Olivier Caron Marie-Emmanuelle Morin-Meschin Florence Polycarpe-Osaer Sophie Giraud Aziz Zaanan Delphine Bonnet Ludovic Mansuy Valérie Bonadona Salima El Chehadeh François Duhoux Marion Gauthier-Villars Jean-Christophe Saurin Marie-Agnès Collonge-Rame Laurence Brugières Qing Wang Brigitte Bressac-de Paillerets Jean-Marc Rey Christine Toulas Marie-Pierre Buisine Myriam Bronner Joanna Sokolowska Agnès Hardouin Anne-Françoise Cailleux Hakim Sebaoui Julien Blot Julie Tinat Jacques Benichou Thierry Frebourg

Eur J Hum Genet 2016 Jan 15;24(1):99-105. Epub 2015 Apr 15.

Inserm U1079, University of Rouen, Institute for Research and Innovation in Biomedicine, Rouen, France.

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http://dx.doi.org/10.1038/ejhg.2015.72	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795220	PMC

January 2016

Diagnosis of Constitutional Mismatch Repair-Deficiency Syndrome Based on Microsatellite Instability and Lymphocyte Tolerance to Methylating Agents.

Authors:

Sahra Bodo Chrystelle Colas Olivier Buhard Ada Collura Julie Tinat Noémie Lavoine Agathe Guilloux Alexandra Chalastanis Philippe Lafitte Florence Coulet Marie-Pierre Buisine Denisa Ilencikova Clara Ruiz-Ponte Miriam Kinzel Sophie Grandjouan Hilde Brems Sophie Lejeune Hélène Blanché Qing Wang Olivier Caron Odile Cabaret Magali Svrcek Dominique Vidaud Béatrice Parfait Alain Verloes Ulrich J Knappe Florent Soubrier Isabelle Mortemousque Alexander Leis Jessie Auclair-Perrossier Thierry Frébourg Jean-François Fléjou Natacha Entz-Werle Julie Leclerc David Malka Odile Cohen-Haguenauer Yael Goldberg Anne-Marie Gerdes Faten Fedhila Michèle Mathieu-Dramard Richard Hamelin Badre Wafaa Marion Gauthier-Villars Franck Bourdeaut Eamonn Sheridan Hans Vasen Laurence Brugières Katharina Wimmer Martine Muleris Alex Duval

Gastroenterology 2015 Oct 25;149(4):1017-29.e3. Epub 2015 Jun 25.

INSERM, UMR_S 938 Centre de Recherche Saint-Antoine, Equipe Instabilité des Microsatellites et Cancer, équipe labellisée par la Ligue Nationle contre le Cancer, Paris, France; UPMC Univ Paris, Paris, France. Electronic address:

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