Publications by authors named "Sophie Cypowyj"

23Publications

Low Circulating Natural Killer Cell Counts are Associated With Severe Disease in Patients With Common Variable Immunodeficiency.

EBioMedicine 2016 Apr 2;6:222-230. Epub 2016 Mar 2.

Centre d'Immunologie de Marseille-Luminy, Aix-Marseille University UM2, 13288 Marseille, France; Inserm U1104, 13288 Marseille, France; CNRS UMR7280, 13288 Marseille, France; MI-mAbs Consortium (Aix Marseille University), CIML, 13288 Marseille, France. Electronic address:

View Article and Find Full Text PDF
April 2016

[Innate Lymphoid Cells: new actors of immunity].

Bull Acad Natl Med 2016 03;200(3):561-72; discussion 573-4

View Article and Find Full Text PDF
March 2016

Innate Lymphoid Cells in Cancer.

Cancer Immunol Res 2015 Oct;3(10):1109-14

Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université UM2, Inserm, U1104, CNRS UMR7280, 13288 Marseille, France. Immunologie, Hôpital de la Conception, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille, France.

View Article and Find Full Text PDF
October 2015

Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis.

J Exp Med 2015 May 27;212(5):619-31. Epub 2015 Apr 27.

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, French Institute of Health and Medical Research (INSERM) U1163, 75015 Paris, France Imagine Institute, Paris Descartes University, 75015 Paris, France St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065

View Article and Find Full Text PDF
May 2015

IL-17 T cells' defective differentiation in vitro despite normal range ex vivo in chronic mucocutaneous candidiasis due to STAT1 mutation.

J Invest Dermatol 2014 Apr 11;134(4):1155-1157. Epub 2013 Nov 11.

Laboratory of Transmission, Control and Immunobiology of Infections (LR11IPT02), Institut Pasteur de Tunis and University Tunis El Manar, Tunis, Tunisia. Electronic address:

View Article and Find Full Text PDF
April 2014

Primary immunodeficiencies underlying fungal infections.

Curr Opin Pediatr 2013 Dec;25(6):736-47

aLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U980 Necker Medical School, Imagine Institute and Paris Descartes University, Sorbonne Paris Cité bInfectious Diseases and Tropical Medicine Unit, Necker-Enfants Malades Hospital, AP-HP and Paris Descartes University cPasteur Institute, National Reference Center of Invasive Mycoses and Antifungals, Paris, France dSt Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, New York, USA eStudy Center for Immunodeficiency fPediatric Hematology-Immunology Unit, Necker Enfants-Malades Hospital, AP-HP, and Paris Descartes University, Sorbonne Paris Cité, Paris, France.

View Article and Find Full Text PDF
December 2013

Deep dermatophytosis and inherited CARD9 deficiency.

N Engl J Med 2013 Oct 16;369(18):1704-1714. Epub 2013 Oct 16.

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM Unité 980 Necker Medical School, Imagine Institute and University Paris Descartes, Sorbonne Paris Cité (F.L., Q.B.V., L.L., M.M., L.A., J.-L.C., C. Picard, A.P.), Infectious Diseases and Tropical Medicine Unit (F.L., O.L.) and Pediatric Hematology-Immunology Unit (J.-L.C.), Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), and University Paris Descartes, Dermatology Unit (H.B.) and Skin Research Institute (L.M.), INSERM Unité 697, Saint Louis Hospital, INSERM Unité 781, Necker-Enfants Malades Hospital (H.B.), Human Histopathology and Animal Models, Infection and Epidemiology Department (G.J., F.C.), and the National Reference Center for Invasive Mycoses and Antifungals, Molecular Mycology Unit (O.L.), Institut Pasteur, and the Pathology Unit (S.F.), Microbiology Unit (M.-E.B.), and Study Center for Immunodeficiency (C. Picard), Necker-Enfants Malades Hospital, AP-HP - all in Paris; University College London, Royal Free Hospital (S.P., B. Grimbacher) and International Foundation for Dermatology, Willan House (R.H.), London; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York (S.C., C. Prando, L.A., J.-L.C.); the Dermatology Unit, Mustapha Hospital and Faculty of Medicine, Algiers (L.T., A.A.-K.), the Dermatology Unit, Dr. T. Damerdji Tlemcen Hospital and Aboubakr Belkaid University, Tlemcen (O.B.S., M.B.), and the Dermatology Unit, Hassani Abdelkader Hospital, and Faculty of Medicine, Djillali Liabes University, Sidi Bel-Abbes (B. Guellil) - all in Algeria; the Infectious Diseases Unit (F.J., J.-C.G., K.S.) and Dermatology Unit (V.M.), Erasme Hospital, Brussels; the Dermatology Unit, Farhat Hached Hospital, Sousse, Tunisia (L.B., M.D., M.L.); the Molecular Immunogenetics Unit, National Center for Scientific Research, UPR 1142, Institute of Human Genetics, and University Montpellier 2, Montpellier, France (G.L.); and the Center for Chronic Immunodeficiency, University Hospital Freiburg, Freiburg, Germany (B. Grimbacher).

View Article and Find Full Text PDF
October 2013

An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.

Immunity 2013 Oct 10;39(4):676-86. Epub 2013 Oct 10.

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065, USA. Electronic address:

View Article and Find Full Text PDF
October 2013

A 1-year-old girl with a gain-of-function STAT1 mutation treated with hematopoietic stem cell transplantation.

J Clin Immunol 2013 Nov 9;33(8):1273-5. Epub 2013 Oct 9.

Allergy and Immunology Division, Hospital Nacional Edgardo Rebagliati Martins, Calle Manuel Candamo 257, Lince, Lima, Peru,

View Article and Find Full Text PDF
November 2013

Molecular mechanisms of mucocutaneous immunity against Candida and Staphylococcus species.

J Allergy Clin Immunol 2012 Nov 3;130(5):1019-27. Epub 2012 Oct 3.

Department of Infectious and Pediatric Immunology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary.

View Article and Find Full Text PDF
November 2012

Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis.

Curr Opin Allergy Clin Immunol 2012 Dec;12(6):616-22

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Inserm U980 and University Paris Descartes, Necker Medical School, Paris Sorbonne Cité, Paris, France.

View Article and Find Full Text PDF
December 2012

Immunity to infection in IL-17-deficient mice and humans.

Eur J Immunol 2012 Sep;42(9):2246-54

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

View Article and Find Full Text PDF
September 2012

Herpes in STAT1 gain-of-function mutation [corrected].

Lancet 2012 Jun;379(9835):2500

Department of Infectious and Paediatric Immunology, Medical and Health Science Centre, University of Debrecen, Debrecen, Hungary. Electronic address:

View Article and Find Full Text PDF
June 2012

Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes.

Curr Opin Immunol 2012 Aug 30;24(4):364-78. Epub 2012 May 30.

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

View Article and Find Full Text PDF
August 2012

Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis.

J Exp Med 2011 Aug 4;208(8):1635-48. Epub 2011 Jul 4.

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Medical School, Institut National de la Santé et de la Recherche Médicale U980 and University Paris Descartes, 75015 Paris, France.

View Article and Find Full Text PDF
August 2011