Publications

Factors affecting treatment outcome in patients with idiopathic nonspecific interstitial pneumonia: a nationwide cohort study.
Respir Res 2017 Dec 6;18(1):204. Epub 2017 Dec 6.
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-707, Republic of Korea.

Clinical significance of cigarette smoking and dust exposure in pulmonary alveolar proteinosis: a Korean national survey.
BMC Pulm Med 2017 Nov 21;17(1):147. Epub 2017 Nov 21.
Division of Pulmonology, Department of Internal Medicine, Institute of Chest Diseases, Severance Hospital, Yonsei University, College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, South Korea.

Role of S100A9 in the development of neutrophilic inflammation in asthmatics and in a murine model.
Clin Immunol 2017 Oct 25;183:158-166. Epub 2017 Aug 25.
Division of Allergy and Respiratory Disease, Soonchunhyang University Bucheon Hospital, 1174 Jung-dong, Bucheon, Gyeonggi-do 420-767, Republic of Korea. Electronic address:


Predicting survival of patients with idiopathic pulmonary fibrosis using GAP score: a nationwide cohort study.
Respir Res 2016 Oct 18;17(1):131. Epub 2016 Oct 18.
Division of Pulmonology, Department of Internal Medicine, Severance Hospital, Institute of Chest Diseases, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul, 120-752, South Korea.

Apolipoprotein A1 Inhibits TGF-β1-Induced Epithelial-to-Mesenchymal Transition of Alveolar Epithelial Cells.
Tuberc Respir Dis (Seoul) 2016 Jul 1;79(3):143-52. Epub 2016 Jul 1.
Division of Allergy and Respiratory Medicine, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.

Comparisons of Prognosis between Surgically and Clinically Diagnosed Idiopathic Pulmonary Fibrosis Using Gap Model: A Korean National Cohort Study.
Medicine (Baltimore) 2016 Mar;95(11):e3105
From the Department of Internal Medicine, Division of Pulmonology, Severance Hospital, Institute of Chest Diseases, Yonsei University College of Medicine, Seoul, Korea (SHL, SYK, MSP); Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center (DSK, JWS); Department of Internal Medicine and Lung Institute, Division of Pulmonary and Critical Care Medicine, Seoul National University College of Medicine (YWK); Division of Pulmonary and Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine (MPC); Department of Internal Medicine, Division of Allergy and Respiratory Medicine, Soonchunhyang University Seoul Hospital (STU); Department of Internal Medicine, Division of Allergy and Respiratory Medicine, Soonchunhyang University Bucheon Hospital (CSP); Department of Internal Medicine, Division of Pulmonology, Gachon University Gil Medical Center (SHJ); Department of Internal Medicine, Division of Pulmonary, Allergy & Critical Care Medicine, Hallym University Kangdong Sacred Heart Hospital (YBP); Department of Internal Medicine, Pulmonary Division, Inha University Hospital (HLL); Department of Internal medicine, Division of Pulmonary Medicine, Chung Ang University College of Medicine (JWS); Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine (EJL); Department of Internal Medicine, Ewha Womans University School of Medicine, Ewha Medical Research Institute (JHL); Department of Internal Medicine, Division of Pulmonary Medicine, Ulsan University Hospital, University of Ulsan College of Medicine (YJ); Department of Internal Medicine, Division of Critical Care and Pulmonary Medicine, Inje University Pusan Paik Hospital (HKL); and Department of Internal Medicine, Division of Allergy and Pulmonology, Bucheon St. Mary's Hospital, The Catholic University of Korea School of Medicine (YHK), Bucheon, Ko

History of pneumonia is a strong risk factor for chronic obstructive pulmonary disease (COPD) exacerbation in South Korea: the Epidemiologic review and Prospective Observation of COPD and Health in Korea (EPOCH) study.
J Thorac Dis 2015 Dec;7(12):2203-13
1 Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea ; 2 St. Paul's Hospital, The Catholic University of Korea, Seoul, Korea ; 3 Kyung Hee University Hospital at Gangdong, Seoul, Korea ; 4 GangNeung Asan Hospital, Gangneung, Korea ; 5 Konkuk University Medical Center, Seoul, Korea ; 6 Konyang University Hospital, Daejeon, Korea ; 7 Gyeongsang National University Hospital, Jinju-si, Korea ; 8 Kyung Hee University Medical Center, Seoul, Korea ; 9 Keimyung University Dongsan Medical Center, Daegu, Korea ; 10 Korea University Guro Hospital, Seoul, Korea ; 11 Daegu Catholic University Medical Center, Daegu, Korea ; 12 Daegu Fatima Hospital, Daegu, Korea ; 13 Dongguk University Gyeongju Hospital, Gyeongju-si, Korea ; 14 Maryknoll Medical Center, Busan, Korea ; 15 Seoul National University Bundang Hospital, Seongnam, Korea ; 16 Asan Medical Center, Seoul, Korea ; 17 Soonchunhyang University Bucheon Hospital, Bucheon, Korea ; 18 Soonchunhyang University Seoul Hospital, Seoul, Korea ; 19 Soonchunhyang University Cheonan Hospital, Cheonan, Korea ; 20 Severance Hospital, Seoul, Korea ; 21 Yeungnam University Medical Center, Daegu, Korea ; 22 Ulsan University Hospital, Ulsan, Korea ; 23 Wonkwang University School of Medicine, Iksan, Korea ; 24 Inje University Sanggye Paik Hospital, Seoul, Korea ; 25 Chung-Ang University Hospital, Seoul, Korea ; 26 Hallym University Kangdong Sacred Heart Hospital, Anyang-si, Korea ; 27 Kyungpook National University Hospital, Daegu, Korea.


Association between occupational dust exposure and prognosis of idiopathic pulmonary fibrosis: a Korean national survey.
Chest 2015 Feb;147(2):465-474
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yonsei University College of Medicine, Yonsei University Health System, Seoul, South Korea. Electronic address:


Genome-wide association study identifies ALLC polymorphisms correlated with FEV₁ change by corticosteroid.
Clin Chim Acta 2014 Sep 2;436:20-6. Epub 2014 May 2.
Department of Life Science, Sogang University, 35, Baekbeom-ro, Mapo-gu, Seoul 121-742, Republic of Korea; Department of Genetic Epidemiology, SNP Genetics, Inc., 35, Baekbeom-ro, Mapo-gu, Seoul 121-742, Republic of Korea. Electronic address:

Retinoic acid receptor alpha: One of plasma biomarkers associated with exacerbation of chronic obstructive pulmonary disease.
COPD 2014 Apr 10;11(2):152-62. Epub 2013 Oct 10.
1Division of Allergy and Respiratory Disease, Genome Research Center, Soonchunhyang University, Bucheon Hospital , Gyeonggi-do , Republic of Korea.

Polymorphisms of ATF6B Are Potentially Associated With FEV1 Decline by Aspirin Provocation in Asthmatics.
Allergy Asthma Immunol Res 2014 Mar 28;6(2):142-8. Epub 2013 Nov 28.
Department of Life Science, Sogang University, Seoul, Korea. ; Department of Genetic Epidemiology, SNP Genetics, Inc., Seoul, Korea.

Elevation of S100 calcium binding protein A9 in sputum of neutrophilic inflammation in severe uncontrolled asthma.
Ann Allergy Asthma Immunol 2013 Oct 24;111(4):268-275.e1. Epub 2013 Jul 24.
Genome Research Center for Allergy and Respiratory Disease, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.

Angiotensin-converting enzyme (ACE) gene polymorphisms are associated with idiopathic pulmonary fibrosis.
Lung 2013 Aug 9;191(4):345-51. Epub 2013 May 9.
Division of Allergy and Respiratory Medicine, Soonchunhyang University Seoul Hospital, 657, Hannam-dong, Yongsan-gu, Seoul, 140-743, South Korea.

Association analysis of tapasin polymorphisms with aspirin-exacerbated respiratory disease in asthmatics.
Pharmacogenet Genomics 2013 Jul;23(7):341-8
Department of Internal Medicine, Genome Research Center for Allergy and Respiratory Disease, Division of Allergy and Respiratory Medicine, Soonchunhyang University Bucheon Hospital, Gyeonggi-do, Republic of Korea.

Association of single nucleotide polymorphisms on Interleukin 17 receptor A (IL17RA) gene with aspirin hypersensitivity in asthmatics.
Hum Immunol 2013 May 5;74(5):598-606. Epub 2012 Dec 5.
Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University Bucheon Hospital, 1174 Jung Dong, Wonmi Ku, Bucheon, Gyeonggi Do, Republic of Korea.

Identification of subtypes of refractory asthma in Korean patients by cluster analysis.
Lung 2013 Feb 10;191(1):87-93. Epub 2012 Nov 10.
Division of Allergy and Respiratory Medicine, Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University Bucheon Hospital, Gyeonggi-do, 420-767, Republic of Korea.


CD55 polymorphisms and risk of aspirin‑exacerbated respiratory disease.
Mol Med Rep 2012 Nov 5;6(5):1087-92. Epub 2012 Sep 5.
Department of Life Science, Sogang University, and Soonchunhyang University Seoul Hospital, Seoul 121-742, Republic of Korea.

A highly sensitive and specific genetic marker to diagnose aspirin-exacerbated respiratory disease using a genome-wide association study.
DNA Cell Biol 2012 Nov 20;31(11):1604-9. Epub 2012 Sep 20.
Division of Allergy and Respiratory Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea.



Air trapping is a major determinant of persistent airway obstruction in asthmatics.
Respir Med 2012 Jun 23;106(6):786-93. Epub 2012 Mar 23.
Genome Research Center for Allergy and Respiratory Disease, Soonchunhyang University Bucheon Hospital, 1174, Jung-Dong, Wonmi-Gu, Bucheon, Gyeonggi-Do 420-020, South Korea.


Association analysis of formyl peptide receptor 2 (FPR2) polymorphisms and aspirin exacerbated respiratory diseases.
J Hum Genet 2012 Apr 1;57(4):247-53. Epub 2012 Mar 1.
Genome Research Center for Allergy and Respiratory Disease, Soonchunhyang University Bucheon Hospital, Wonmi-gu, Bucheon, Republic of Korea.




The association of a single-nucleotide polymorphism of the IL-2 inducible T-cell Kinase gene with asthma.
Ann Hum Genet 2011 May 15;75(3):359-69. Epub 2011 Feb 15.
Asthma Genome Research Group, Soonchunhyang University Hospital, Jung-Dong, Wonmi-Gu, Bucheon, Gyeonggi-Do, Korea.


Association analysis of RGS7BP gene polymorphisms with aspirin intolerance in asthmatic patients.
Ann Allergy Asthma Immunol 2011 Apr 8;106(4):292-300.e6. Epub 2011 Jan 8.
Genome Research Center for Allergy and Respiratory Disease, Soonchunhyang University Bucheon Hospital, Gyeonggi-do, Republic of Korea.

Association analysis of thromboxane A synthase 1 gene polymorphisms with aspirin intolerance in asthmatic patients.
Pharmacogenomics 2011 Mar;12(3):351-63
Genome Research Center for Allergy & Respiratory Disease, Soonchunhyang University Bucheon Hospital, 1174 Jung-dong, Wonmi-gu, Bucheon, Gyeonggi-do, 420-767, Republic of Korea.




Association of IKBA gene polymorphisms with the development of asthma.
Hum Immunol 2010 Nov 29;71(11):1147-53. Epub 2010 Jul 29.
Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University of Bucheon Hospital, Gyeonggi Do, Korea.



Role of lung apolipoprotein A-I in idiopathic pulmonary fibrosis: antiinflammatory and antifibrotic effect on experimental lung injury and fibrosis.
Am J Respir Crit Care Med 2010 Sep 12;182(5):633-42. Epub 2010 May 12.
Division of Allergy and Respiratory Medicine, Department of Internal Medicine, Soonchunhyang University, Bucheon Hospital, 1174 Jung-Dong, Wonmi-Ku, Bucheon, Kyeonggi-Do, South Korea.

Association between colony-stimulating factor 1 receptor gene polymorphisms and asthma risk.
Hum Genet 2010 Sep 24;128(3):293-302. Epub 2010 Jun 24.
Department of Internal Medicine, Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University Bucheon Hospital, Jung Dong, Wonmi Ku, Gyeonggi Do, Korea.



A nationwide survey of lymphangioleiomyomatosis in Korea: recent increase in newly diagnosed patients.
J Korean Med Sci 2010 Aug 21;25(8):1182-6. Epub 2010 Jul 21.
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.


Association analysis of N-acetyl transferase-2 polymorphisms with aspirin intolerance among asthmatics.
Pharmacogenomics 2010 Jul;11(7):951-8
Genome Research Center for Allergy & Respiratory Disease, Soonchunhyang University Bucheon Hospital, 1174 Jung-dong, Wonmi-gu, Bucheon, Gyeonggi-do 420-767, Republic of Korea.


Clinical features and outcomes of idiopathic pulmonary alveolar proteinosis in Korean population.
J Korean Med Sci 2010 Mar 17;25(3):393-8. Epub 2010 Feb 17.
Division of Pulmonary Medicine, Department of Internal Medicine, Yonsei University, College of Medicine, Yonsei University Health System, Seoul, Korea.

Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization.
BMC Med Genet 2009 Oct 20;10:106. Epub 2009 Oct 20.
Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University Bucheon Hospital, 1174, Jung Dong, Wonmi Ku, Bucheon, Gyeonggi Do, 420-767, Korea.

Association analysis of peroxisome proliferator-activated receptors gamma gene polymorphisms with asprin hypersensitivity in asthmatics.
Allergy Asthma Immunol Res 2009 Oct 25;1(1):30-5. Epub 2009 Sep 25.
Genome Research Center for Allergy and Respiratory Disease, Soonchunhyang University, Bucheon Hospital, Bucheon, Korea.

Interleukin-13 and its receptors in idiopathic interstitial pneumonia: clinical implications for lung function.
J Korean Med Sci 2009 Aug 29;24(4):614-20. Epub 2009 Jul 29.
Genome Research Center for Allergy and Respiratory Disease, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.

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