Soo Heon Kwak

Soo Heon Kwak

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Soo Heon Kwak

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Heritability estimation of dichotomous phenotypes using a liability threshold model on ascertained family-based samples.

Genet Epidemiol 2019 Jul 12. Epub 2019 Jul 12.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1002/gepi.22244DOI Listing
July 2019

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.

Authors:
Jason Flannick Josep M Mercader Christian Fuchsberger Miriam S Udler Anubha Mahajan Jennifer Wessel Tanya M Teslovich Lizz Caulkins Ryan Koesterer Francisco Barajas-Olmos Thomas W Blackwell Eric Boerwinkle Jennifer A Brody Federico Centeno-Cruz Ling Chen Siying Chen Cecilia Contreras-Cubas Emilio Córdova Adolfo Correa Maria Cortes Ralph A DeFronzo Lawrence Dolan Kimberly L Drews Amanda Elliott James S Floyd Stacey Gabriel Maria Eugenia Garay-Sevilla Humberto García-Ortiz Myron Gross Sohee Han Nancy L Heard-Costa Anne U Jackson Marit E Jørgensen Hyun Min Kang Megan Kelsey Bong-Jo Kim Heikki A Koistinen Johanna Kuusisto Joseph B Leader Allan Linneberg Ching-Ti Liu Jianjun Liu Valeriya Lyssenko Alisa K Manning Anthony Marcketta Juan Manuel Malacara-Hernandez Angélica Martínez-Hernández Karen Matsuo Elizabeth Mayer-Davis Elvia Mendoza-Caamal Karen L Mohlke Alanna C Morrison Anne Ndungu Maggie C Y Ng Colm O'Dushlaine Anthony J Payne Catherine Pihoker Wendy S Post Michael Preuss Bruce M Psaty Ramachandran S Vasan N William Rayner Alexander P Reiner Cristina Revilla-Monsalve Neil R Robertson Nicola Santoro Claudia Schurmann Wing Yee So Xavier Soberón Heather M Stringham Tim M Strom Claudia H T Tam Farook Thameem Brian Tomlinson Jason M Torres Russell P Tracy Rob M van Dam Marijana Vujkovic Shuai Wang Ryan P Welch Daniel R Witte Tien-Yin Wong Gil Atzmon Nir Barzilai John Blangero Lori L Bonnycastle Donald W Bowden John C Chambers Edmund Chan Ching-Yu Cheng Yoon Shin Cho Francis S Collins Paul S de Vries Ravindranath Duggirala Benjamin Glaser Clicerio Gonzalez Ma Elena Gonzalez Leif Groop Jaspal Singh Kooner Soo Heon Kwak Markku Laakso Donna M Lehman Peter Nilsson Timothy D Spector E Shyong Tai Tiinamaija Tuomi Jaakko Tuomilehto James G Wilson Carlos A Aguilar-Salinas Erwin Bottinger Brian Burke David J Carey Juliana C N Chan Josée Dupuis Philippe Frossard Susan R Heckbert Mi Yeong Hwang Young Jin Kim H Lester Kirchner Jong-Young Lee Juyoung Lee Ruth J F Loos Ronald C W Ma Andrew D Morris Christopher J O'Donnell Colin N A Palmer James Pankow Kyong Soo Park Asif Rasheed Danish Saleheen Xueling Sim Kerrin S Small Yik Ying Teo Christopher Haiman Craig L Hanis Brian E Henderson Lorena Orozco Teresa Tusié-Luna Frederick E Dewey Aris Baras Christian Gieger Thomas Meitinger Konstantin Strauch Leslie Lange Niels Grarup Torben Hansen Oluf Pedersen Philip Zeitler Dana Dabelea Goncalo Abecasis Graeme I Bell Nancy J Cox Mark Seielstad Rob Sladek James B Meigs Steve S Rich Jerome I Rotter David Altshuler Noël P Burtt Laura J Scott Andrew P Morris Jose C Florez Mark I McCarthy Michael Boehnke

Nature 2019 06 22;570(7759):71-76. Epub 2019 May 22.

Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.

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http://www.nature.com/articles/s41586-019-1231-2
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http://dx.doi.org/10.1038/s41586-019-1231-2DOI Listing
June 2019

Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus.

Diabetologia 2019 02 23;62(2):238-248. Epub 2018 Nov 23.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101 Daehak-ro, Seoul, Jongno-gu, 03080, South Korea.

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http://dx.doi.org/10.1007/s00125-018-4779-8DOI Listing
February 2019

Progression to Gestational Diabetes Mellitus in Pregnant Women with One Abnormal Value in Repeated Oral Glucose Tolerance Tests.

Diabetes Metab J 2019 Feb 28. Epub 2019 Feb 28.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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https://e-dmj.org/DOIx.php?id=10.4093/dmj.2018.0159
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http://dx.doi.org/10.4093/dmj.2018.0159DOI Listing
February 2019

Pregnancy Outcomes of Women Additionally Diagnosed as Gestational Diabetes by the International Association of the Diabetes and Pregnancy Study Groups Criteria.

Diabetes Metab J 2019 Feb 28. Epub 2019 Feb 28.

Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

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https://e-dmj.org/DOIx.php?id=10.4093/dmj.2018.0192
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http://dx.doi.org/10.4093/dmj.2018.0192DOI Listing
February 2019

DNA methylation profiles in sibling pairs discordant for intrauterine exposure to maternal gestational diabetes.

Epigenetics 2017 27;12(10):825-832. Epub 2017 Nov 27.

d Department of Internal Medicine , Seoul National University Bundang Hospital , Seongnam , Republic of Korea.

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http://dx.doi.org/10.1080/15592294.2017.1370172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788413PMC
October 2018

Fimasartan increases glucose-stimulated insulin secretion in patients with type 2 diabetes and hypertension compared with amlodipine.

Diabetes Obes Metab 2018 07 6;20(7):1670-1677. Epub 2018 Apr 6.

Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

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http://doi.wiley.com/10.1111/dom.13282
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http://dx.doi.org/10.1111/dom.13282DOI Listing
July 2018

Pathophysiology of Type 2 Diabetes in Koreans.

Endocrinol Metab (Seoul) 2018 Mar;33(1):9-16

Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.

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http://dx.doi.org/10.3803/EnM.2018.33.1.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874201PMC
March 2018

Sodium-glucose cotransporter-2 inhibition improves incretin sensitivity of pancreatic β-cells in people with type 2 diabetes.

Diabetes Obes Metab 2018 02 2;20(2):370-377. Epub 2017 Oct 2.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1111/dom.13081DOI Listing
February 2018

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Authors:
Jason Flannick Christian Fuchsberger Anubha Mahajan Tanya M Teslovich Vineeta Agarwala Kyle J Gaulton Lizz Caulkins Ryan Koesterer Clement Ma Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Dennis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeri Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana C N Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Laura J Scott Andrew P Morris Hyun Min Kang David Altshuler Noël P Burtt Jose C Florez Michael Boehnke Mark I McCarthy

Sci Data 2018 01 23;5:180002. Epub 2018 Jan 23.

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http://dx.doi.org/10.1038/sdata.2018.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779067PMC
January 2018

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Authors:
Jason Flannick Christian Fuchsberger Anubha Mahajan Tanya M Teslovich Vineeta Agarwala Kyle J Gaulton Lizz Caulkins Ryan Koesterer Clement Ma Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Dennis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeri Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana Cn Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Laura J Scott Andrew P Morris Hyun Min Kang David Altshuler Noël P Burtt Jose C Florez Michael Boehnke Mark I McCarthy

Sci Data 2017 12 19;4:170179. Epub 2017 Dec 19.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/sdata.2017.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735917PMC
December 2017

Findings of a 1303 Korean whole-exome sequencing study.

Exp Mol Med 2017 07 14;49(7):e356. Epub 2017 Jul 14.

Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.

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http://dx.doi.org/10.1038/emm.2017.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565953PMC
July 2017

Selecting cases and controls for DNA sequencing studies using family histories of disease.

Stat Med 2017 06 21;36(13):2081-2099. Epub 2017 Feb 21.

Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1002/sim.7248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810411PMC
June 2017

Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus.

Korean J Intern Med 2017 Jan 1;32(1):26-41. Epub 2017 Jan 1.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3904/kjim.2016.203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214732PMC
January 2017

Genetic-risk assessment of GWAS-derived susceptibility loci for type 2 diabetes in a 10 year follow-up of a population-based cohort study.

J Hum Genet 2016 Dec 21;61(12):1009-1012. Epub 2016 Jul 21.

Division of Structural and Functional Genomics, The Center for Genome Science, Korea National Institute of Health, KCDC, Osong, Republic of Korea.

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http://dx.doi.org/10.1038/jhg.2016.93DOI Listing
December 2016

Clinical whole exome sequencing in early onset diabetes patients.

Diabetes Res Clin Pract 2016 Dec 15;122:71-77. Epub 2016 Oct 15.

Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2016.10.005DOI Listing
December 2016

Serum bilirubin levels are positively associated with glycemic variability in women with type 2 diabetes.

J Diabetes Investig 2016 Nov 4;7(6):874-880. Epub 2016 Jun 4.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/jdi.12529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089950PMC
November 2016

A genetic variant in GLP1R is associated with response to DPP-4 inhibitors in patients with type 2 diabetes.

Medicine (Baltimore) 2016 Nov;95(44):e5155

aDivision of Endocrinology and Metabolism, Department of Internal MedicinebGraduate school, Yonsei University College of MedicinecDivision of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of UlsandBrain Korea 21 Plus Project for Medical ScienceeDivision of Cardiology, Department of Internal MedicinefDepartment of Pharmacology, Yonsei University College of MedicinegDivision of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University College of Medicine, SeoulhDivision of Endocrinology and Metabolism, Department of Internal Medicine, Hallym University Medical College, Gyeonggi-do, Korea.

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http://dx.doi.org/10.1097/MD.0000000000005155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591096PMC
November 2016

Anti-programmed cell death 1 therapy triggering diabetic ketoacidosis and fulminant type 1 diabetes.

Acta Diabetol 2016 Oct 14;53(5):853-6. Epub 2016 Jun 14.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1007/s00592-016-0872-yDOI Listing
October 2016

The genetic architecture of type 2 diabetes.

Authors:
Christian Fuchsberger Jason Flannick Tanya M Teslovich Anubha Mahajan Vineeta Agarwala Kyle J Gaulton Clement Ma Pierre Fontanillas Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Denis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Yvonne T van der Schouw Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeriya Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana C N Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Noël P Burtt Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Jose C Florez Laura J Scott Andrew P Morris Hyun Min Kang Michael Boehnke David Altshuler Mark I McCarthy

Nature 2016 08 11;536(7614):41-47. Epub 2016 Jul 11.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://hmg.oxfordjournals.org/content/early/2015/07/21/hmg.d
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http://www.nature.com/doifinder/10.1038/nature18642
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http://dx.doi.org/10.1038/nature18642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034897PMC
August 2016

Metabolic syndrome independently predicts future diabetes in women with a history of gestational diabetes mellitus.

Medicine (Baltimore) 2016 Aug;95(35):e4582

aDepartment of Preventive Medicine, Ajou University School of Medicine, Suwon bDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul cDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam dDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea eDivision of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Medical School, Chicago, IL.

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http://dx.doi.org/10.1097/MD.0000000000004582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008552PMC
August 2016

Feasibility of a Patient-Centered, Smartphone-Based, Diabetes Care System: A Pilot Study.

Diabetes Metab J 2016 Jun 21;40(3):192-201. Epub 2016 Apr 21.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4093/dmj.2016.40.3.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929223PMC
June 2016

Role of mitochondrial DNA variation in the pathogenesis of diabetes mellitus.

Front Biosci (Landmark Ed) 2016 06 1;21:1151-67. Epub 2016 Jun 1.

Department of Internal Medicine, Seoul National University Hospital, and Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea,

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June 2016

1,5-Anhydro-D-Glucitol Could Reflect Hypoglycemia Risk in Patients with Type 2 Diabetes Receiving Insulin Therapy.

Endocrinol Metab (Seoul) 2016 Jun 27;31(2):284-91. Epub 2016 May 27.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3803/EnM.2016.31.2.284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923413PMC
June 2016

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ.

Exp Mol Med 2016 05 20;48:e234. Epub 2016 May 20.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1038/emm.2016.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910150PMC
May 2016

The Level of Autoantibodies Targeting Eukaryote Translation Elongation Factor 1 α1 and Ubiquitin-Conjugating Enzyme 2L3 in Nondiabetic Young Adults.

Diabetes Metab J 2016 Apr;40(2):154-60

Department of Systems Immunology, College of Biomedical Science and the Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, Korea.

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http://dx.doi.org/10.4093/dmj.2016.40.2.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853223PMC
April 2016

Comparison between two methods of bioelectrical impedance analyses for accuracy in measuring abdominal visceral fat area.

J Diabetes Complications 2016 Mar 24;30(2):343-9. Epub 2015 Oct 24.

Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jdiacomp.2015.10.014DOI Listing
March 2016

Recent progress in genetic and epigenetic research on type 2 diabetes.

Exp Mol Med 2016 Mar 11;48:e220. Epub 2016 Mar 11.

Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.

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http://dx.doi.org/10.1038/emm.2016.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892885PMC
March 2016

10-year trajectory of β-cell function and insulin sensitivity in the development of type 2 diabetes: a community-based prospective cohort study.

Lancet Diabetes Endocrinol 2016 Jan 11;4(1):27-34. Epub 2015 Nov 11.

Department of Preventive Medicine, Ajou University School of Medicine, Suwon, South Korea. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(15)00336-8DOI Listing
January 2016

Clinical Characteristics of Subjects with Sulfonylurea-Dependent Type 2 Diabetes.

Endocrinol Metab (Seoul) 2015 Dec 10;30(4):509-13. Epub 2015 Sep 10.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3803/EnM.2015.30.4.509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722406PMC
December 2015

Association of HLA Genotype and Fulminant Type 1 Diabetes in Koreans.

Genomics Inform 2015 Dec 31;13(4):126-31. Epub 2015 Dec 31.

Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.

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http://dx.doi.org/10.5808/GI.2015.13.4.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742322PMC
December 2015

Identification of Two Cases of Ciliopathy-Associated Diabetes and Their Mutation Analysis Using Whole Exome Sequencing.

Diabetes Metab J 2015 Oct 22;39(5):439-43. Epub 2015 Oct 22.

Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.4093/dmj.2015.39.5.439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641974PMC
October 2015

Weight Gain and Progression to Type 2 Diabetes in Women With a History of Gestational Diabetes Mellitus.

J Clin Endocrinol Metab 2015 Sep 14;100(9):3548-55. Epub 2015 Jul 14.

Department of Internal Medicine (J.H.M., S.H.K., H.S.J., S.H.C., S.L., Y.M.C., K.S.P., H.C.J.), Seoul National University College of Medicine, Seoul 110-744, Korea; Department of Internal Medicine (J.H.M., S.H.K., H.S.J., Y.M.C., K.S.P.), Seoul National University Hospital, Seoul 110-799, Korea; and Department of Internal Medicine (S.H.C., S.L., H.C.J.), Seoul National University Bundang Hospital, Seongnam 463-707, Korea; and Department of Preventive Medicine (N.H.C.), Ajou University School of Medicine, Suwon 443-721, Korea.

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http://dx.doi.org/10.1210/JC.2015-1113DOI Listing
September 2015

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

Nat Commun 2015 Jul 3;6:7585. Epub 2015 Jul 3.

1] Institute of Molecular Biology and Genetics, Seoul National University, Seoul 151-742, Korea [2] School of Biological Sciences, Seoul National University, Seoul 151-742, Korea.

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http://dx.doi.org/10.1038/ncomms8585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506505PMC
July 2015

Serum aryl hydrocarbon receptor ligand activity is associated with insulin resistance and resulting type 2 diabetes.

Acta Diabetol 2015 Jun 11;52(3):489-95. Epub 2014 Nov 11.

Department of Internal Medicine, Seoul National University Hospital, Seoul, 110-744, Korea.

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http://dx.doi.org/10.1007/s00592-014-0674-zDOI Listing
June 2015

Genetic Studies on Diabetic Microvascular Complications: Focusing on Genome-Wide Association Studies.

Endocrinol Metab (Seoul) 2015 Jun;30(2):147-58

Department of Internal Medicine, Seoul National University Hospital; Depatment of Internal Medicine, Seoul National University College of Medicine; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.3803/EnM.2015.30.2.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508258PMC
June 2015

Identification and Functional Characterization of P159L Mutation in HNF1B in a Family with Maturity-Onset Diabetes of the Young 5 (MODY5).

Genomics Inform 2014 Dec 31;12(4):240-6. Epub 2014 Dec 31.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-744, Korea. ; Department of Internal Medicine, Seoul National University Hospital, Seoul 110-744, Korea. ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 110-744, Korea.

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http://dx.doi.org/10.5808/GI.2014.12.4.240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330261PMC
December 2014

Identification of novel autoantibodies in type 1 diabetic patients using a high-density protein microarray.

Diabetes 2014 Sep 19;63(9):3022-32. Epub 2014 Jun 19.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul, Korea

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http://diabetes.diabetesjournals.org/content/63/9/3022.full.
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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db13-15
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http://dx.doi.org/10.2337/db13-1566DOI Listing
September 2014

Assessment of diabetic polyneuropathy and autonomic neuropathy using current perception threshold in korean patients with diabetes mellitus.

Diabetes Metab J 2014 Aug 20;38(4):285-93. Epub 2014 Aug 20.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ; Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4093/dmj.2014.38.4.285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160582PMC
August 2014

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

Authors:
Anubha Mahajan Min Jin Go Weihua Zhang Jennifer E Below Kyle J Gaulton Teresa Ferreira Momoko Horikoshi Andrew D Johnson Maggie C Y Ng Inga Prokopenko Danish Saleheen Xu Wang Eleftheria Zeggini Goncalo R Abecasis Linda S Adair Peter Almgren Mustafa Atalay Tin Aung Damiano Baldassarre Beverley Balkau Yuqian Bao Anthony H Barnett Ines Barroso Abdul Basit Latonya F Been John Beilby Graeme I Bell Rafn Benediktsson Richard N Bergman Bernhard O Boehm Eric Boerwinkle Lori L Bonnycastle Noël Burtt Qiuyin Cai Harry Campbell Jason Carey Stephane Cauchi Mark Caulfield Juliana C N Chan Li-Ching Chang Tien-Jyun Chang Yi-Cheng Chang Guillaume Charpentier Chien-Hsiun Chen Han Chen Yuan-Tsong Chen Kee-Seng Chia Manickam Chidambaram Peter S Chines Nam H Cho Young Min Cho Lee-Ming Chuang Francis S Collins Marylin C Cornelis David J Couper Andrew T Crenshaw Rob M van Dam John Danesh Debashish Das Ulf de Faire George Dedoussis Panos Deloukas Antigone S Dimas Christian Dina Alex S Doney Peter J Donnelly Mozhgan Dorkhan Cornelia van Duijn Josée Dupuis Sarah Edkins Paul Elliott Valur Emilsson Raimund Erbel Johan G Eriksson Jorge Escobedo Tonu Esko Elodie Eury Jose C Florez Pierre Fontanillas Nita G Forouhi Tom Forsen Caroline Fox Ross M Fraser Timothy M Frayling Philippe Froguel Philippe Frossard Yutang Gao Karl Gertow Christian Gieger Bruna Gigante Harald Grallert George B Grant Leif C Grrop Chrisropher J Groves Elin Grundberg Candace Guiducci Anders Hamsten Bok-Ghee Han Kazuo Hara Neelam Hassanali Andrew T Hattersley Caroline Hayward Asa K Hedman Christian Herder Albert Hofman Oddgeir L Holmen Kees Hovingh Astradur B Hreidarsson Cheng Hu Frank B Hu Jennie Hui Steve E Humphries Sarah E Hunt David J Hunter Kristian Hveem Zafar I Hydrie Hiroshi Ikegami Thomas Illig Erik Ingelsson Muhammed Islam Bo Isomaa Anne U Jackson Tazeen Jafar Alan James Weiping Jia Karl-Heinz Jöckel Anna Jonsson Jeremy B M Jowett Takashi Kadowaki Hyun Min Kang Stavroula Kanoni Wen Hong L Kao Sekar Kathiresan Norihiro Kato Prasad Katulanda Kirkka M Keinanen-Kiukaanniemi Ann M Kelly Hassan Khan Kay-Tee Khaw Chiea-Chuen Khor Hyung-Lae Kim Sangsoo Kim Young Jin Kim Leena Kinnunen Norman Klopp Augustine Kong Eeva Korpi-Hyövälti Sudhir Kowlessur Peter Kraft Jasmina Kravic Malene M Kristensen S Krithika Ashish Kumar Jesus Kumate Johanna Kuusisto Soo Heon Kwak Markku Laakso Vasiliki Lagou Timo A Lakka Claudia Langenberg Cordelia Langford Robert Lawrence Karin Leander Jen-Mai Lee Nanette R Lee Man Li Xinzhong Li Yun Li Junbin Liang Samuel Liju Wei-Yen Lim Lars Lind Cecilia M Lindgren Eero Lindholm Ching-Ti Liu Jian Jun Liu Stéphane Lobbens Jirong Long Ruth J F Loos Wei Lu Jian'an Luan Valeriya Lyssenko Ronald C W Ma Shiro Maeda Reedik Mägi Satu Männisto David R Matthews James B Meigs Olle Melander Andres Metspalu Julia Meyer Ghazala Mirza Evelin Mihailov Susanne Moebus Viswanathan Mohan Karen L Mohlke Andrew D Morris Thomas W Mühleisen Martina Müller-Nurasyid Bill Musk Jiro Nakamura Eitaro Nakashima Pau Navarro Peng-Keat Ng Alexandra C Nica Peter M Nilsson Inger Njølstad Markus M Nöthen Keizo Ohnaka Twee Hee Ong Katharine R Owen Colin N A Palmer James S Pankow Kyong Soo Park Melissa Parkin Sonali Pechlivanis Nancy L Pedersen Leena Peltonen John R B Perry Annette Peters Janini M Pinidiyapathirage Carl G Platou Simon Potter Jackie F Price Lu Qi Venkatesan Radha Loukianos Rallidis Asif Rasheed Wolfgang Rathman Rainer Rauramaa Soumya Raychaudhuri N William Rayner Simon D Rees Emil Rehnberg Samuli Ripatti Neil Robertson Michael Roden Elizabeth J Rossin Igor Rudan Denis Rybin Timo E Saaristo Veikko Salomaa Juha Saltevo Maria Samuel Dharambir K Sanghera Jouko Saramies James Scott Laura J Scott Robert A Scott Ayellet V Segrè Joban Sehmi Bengt Sennblad Nabi Shah Sonia Shah A Samad Shera Xiao Ou Shu Alan R Shuldiner Gunnar Sigurđsson Eric Sijbrands Angela Silveira Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Wing Yee So Alena Stančáková Kari Stefansson Gerald Steinbach Valgerdur Steinthorsdottir Kathleen Stirrups Rona J Strawbridge Heather M Stringham Qi Sun Chen Suo Ann-Christine Syvänen Ryoichi Takayanagi Fumihiko Takeuchi Wan Ting Tay Tanya M Teslovich Barbara Thorand Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Joseph Trakalo Elena Tremoli Mieke D Trip Fuu Jen Tsai Tiinamaija Tuomi Jaakko Tuomilehto Andre G Uitterlinden Adan Valladares-Salgado Sailaja Vedantam Fabrizio Veglia Benjamin F Voight Congrong Wang Nicholas J Wareham Roman Wennauer Ananda R Wickremasinghe Tom Wilsgaard James F Wilson Steven Wiltshire Wendy Winckler Tien Yin Wong Andrew R Wood Jer-Yuarn Wu Ying Wu Ken Yamamoto Toshimasa Yamauchi Mingyu Yang Loic Yengo Mitsuhiro Yokota Robin Young Delilah Zabaneh Fan Zhang Rong Zhang Wei Zheng Paul Z Zimmet David Altshuler Donald W Bowden Yoon Shin Cho Nancy J Cox Miguel Cruz Craig L Hanis Jaspal Kooner Jong-Young Lee Mark Seielstad Yik Ying Teo Michael Boehnke Esteban J Parra Jonh C Chambers E Shyong Tai Mark I McCarthy Andrew P Morris

Nat Genet 2014 Mar 9;46(3):234-44. Epub 2014 Feb 9.

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http://dx.doi.org/10.1038/ng.2897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969612PMC
March 2014

Prediction of type 2 diabetes in women with a history of gestational diabetes using a genetic risk score.

Diabetologia 2013 Dec 22;56(12):2556-63. Epub 2013 Sep 22.

Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-Ro, Chongno-Gu, Seoul, 110-744, South Korea.

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http://dx.doi.org/10.1007/s00125-013-3059-xDOI Listing
December 2013

A novel mutation in the von hippel-lindau tumor suppressor gene identified in a patient presenting with gestational diabetes mellitus.

Endocrinol Metab (Seoul) 2013 Dec 12;28(4):320-5. Epub 2013 Dec 12.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3803/EnM.2013.28.4.320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871045PMC
December 2013

New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.

J Hum Genet 2013 Jun 11;58(6):362-5. Epub 2013 Apr 11.

Division of Structural and Functional Genomics, Center for Genome Science, Korea National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.

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http://dx.doi.org/10.1038/jhg.2013.14DOI Listing
June 2013

F-box only protein 9 is required for adipocyte differentiation.

Biochem Biophys Res Commun 2013 May 3;435(2):239-43. Epub 2013 May 3.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2013.04.072DOI Listing
May 2013

Clinical and genetic risk factors for type 2 diabetes at early or late post partum after gestational diabetes mellitus.

J Clin Endocrinol Metab 2013 Apr 7;98(4):E744-52. Epub 2013 Mar 7.

Department of Internal Medicine, Seoul National University Hospital, Seoul, 110-744, Korea.

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http://dx.doi.org/10.1210/jc.2012-3324DOI Listing
April 2013

Two cases of methimazole-induced insulin autoimmune syndrome in graves' disease.

Endocrinol Metab (Seoul) 2013 Mar 25;28(1):55-60. Epub 2013 Mar 25.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3803/EnM.2013.28.1.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811805PMC
March 2013

Genetics of type 2 diabetes and potential clinical implications.

Arch Pharm Res 2013 Feb 2;36(2):167-77. Epub 2013 Feb 2.

Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.

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http://dx.doi.org/10.1007/s12272-013-0021-xDOI Listing
February 2013

Identification of a genetic locus on chromosome 4q34-35 for type 2 diabetes with overweight.

Exp Mol Med 2013 Feb 8;45:e7. Epub 2013 Feb 8.

Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, Korea.

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http://dx.doi.org/10.1038/emm.2013.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584667PMC
February 2013

Finding genetic risk factors of gestational diabetes.

Genomics Inform 2012 Dec 31;10(4):239-43. Epub 2012 Dec 31.

Department of Internal Medicine, Seoul National University Hospital, Seoul 110-744, Korea.

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http://dx.doi.org/10.5808/GI.2012.10.4.239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543924PMC
December 2012

Genome-wide association study identifies GYS2 as a novel genetic factor for polycystic ovary syndrome through obesity-related condition.

J Hum Genet 2012 Oct 6;57(10):660-4. Epub 2012 Sep 6.

Center for Genome Science, National Institute of Health, Osong Health Technology Administration complex, Chungcheongbuk-do, Republic of Korea.

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http://dx.doi.org/10.1038/jhg.2012.92DOI Listing
October 2012

Relationship of 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase gene polymorphisms with metabolic syndrome and type 2 diabetes.

Endocr J 2011 23;58(11):949-59. Epub 2011 Aug 23.

Department of Internal medicine, Dongguk University School of Medicine, Gyeongju, South Korea.

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June 2012

Association of variations in TPH1 and HTR2B with gestational weight gain and measures of obesity.

Obesity (Silver Spring) 2012 Jan 11;20(1):233-8. Epub 2011 Aug 11.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1038/oby.2011.253DOI Listing
January 2012

Plasma vaspin concentrations are elevated in metabolic syndrome in men and are correlated with coronary atherosclerosis in women.

Clin Endocrinol (Oxf) 2011 Nov;75(5):628-35

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/j.1365-2265.2011.04095.xDOI Listing
November 2011

Gender differences in diagnostic values of visceral fat area and waist circumference for predicting metabolic syndrome in Koreans.

J Korean Med Sci 2011 Jul 20;26(7):906-13. Epub 2011 Jun 20.

Divisions of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3346/jkms.2011.26.7.906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124721PMC
July 2011

Polymorphisms in KCNQ1 are associated with gestational diabetes in a Korean population.

Horm Res Paediatr 2010 3;74(5):333-8. Epub 2010 Jul 3.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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https://www.karger.com/Article/FullText/313918
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http://dx.doi.org/10.1159/000313918DOI Listing
February 2011

Mitochondrial metabolism and diabetes.

J Diabetes Investig 2010 Oct;1(5):161-9

Department of Internal Medicine, Eulji University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/j.2040-1124.2010.00047.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020716PMC
October 2010

Mitochondrial dysfunction and metabolic syndrome-looking for environmental factors.

Biochim Biophys Acta 2010 Mar 13;1800(3):282-9. Epub 2009 Nov 13.

Department of Internal Medicine, School of Medicine, Seoul National University, Yongon-Dong, Chongno-Gu, Seoul 110-744, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbagen.2009.11.010DOI Listing
March 2010

Atypical hemolytic uremic syndrome associated with complement factor H autoantibodies and CFHR1/CFHR3 deficiency.

Pediatr Res 2009 Sep;66(3):336-40

Department of Pediatrics, Kidney Research Institute, Seoul National University College of Medicine, Seoul 110-744, Korea.

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http://dx.doi.org/10.1203/PDR.0b013e3181b1bd4aDOI Listing
September 2009

Regulatory effect of common promoter polymorphisms on the expression of the 11beta-hydroxysteroid dehydrogenase type 1 gene.

Horm Res 2009 30;72(1):25-32. Epub 2009 Jun 30.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1159/000224337DOI Listing
September 2009

Subsequent pregnancy after gestational diabetes mellitus: frequency and risk factors for recurrence in Korean women.

Diabetes Care 2008 Sep 5;31(9):1867-71. Epub 2008 Jun 5.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.2337/dc08-0384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518361PMC
September 2008

High plasma retinol binding protein-4 and low plasma adiponectin concentrations are associated with severity of glucose intolerance in women with previous gestational diabetes mellitus.

J Clin Endocrinol Metab 2008 Aug 20;93(8):3142-8. Epub 2008 May 20.

Division of Endocrinology and Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Bundang-Ku, Sungnam City, Gyeonggi-Do 463-707, South Korea.

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http://dx.doi.org/10.1210/jc.2007-1755DOI Listing
August 2008

Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes.

Diabetes Care 2006 Nov;29(11):2457-61

Department of Internal Medicine, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.

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http://care.diabetesjournals.org/cgi/doi/10.2337/dc06-0360
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http://dx.doi.org/10.2337/dc06-0360DOI Listing
November 2006