Publications by authors named "Soni Kottayi"

5 Publications

  • Page 1 of 1

Evaluation of antifungal activity of six children's toothpaste on isolated from early childhood caries patients.

J Indian Soc Pedod Prev Dent 2020 Apr-Jun;38(2):152-157

Department of Pediatric and Preventive Dentistry, Kannur Dental College, Kannur, Kerala, India.

Background: Early childhood caries (ECC) is an aggressive, destructive form of dental caries that affects the children younger than 6 years of age. Candida is known to increase the adherence of Streptococcus mutans to the oral biofilm and produce acids that cause tooth demineralization.

Aim Of The Study: To evaluate the efficacy of six commercially available children's toothpaste on clinical isolates of Candida albicans obtained from ECC patients.

Materials And Methods: The study population comprised 60 children aged 3-6 years having ECC. Samples were divided into six groups comprising ten children in each group. Samples were collected using sterile cotton swabs, inoculated on Sabouraud dextrose agar, and incubated at 37°C for 24 h. Species identification was done by germ tube test and growth on corn meal agar. After the confirmed growth of C. albicans, the six commercially available children's toothpaste namely Organic Children's Coconut Oil Toothpaste, Aloe Dent Children's Toothpaste, Patanjali Dant Kanti Junior Toothpaste, Colgate Kids Toothpaste, Pediflor Kids Toothpaste, and Crest Pro-Health Stages Kids Toothpaste and distilled water as control group were subjected for antifungal activity of C. albicans. Agar plates were incubated at 37°C for 48 h, and the diameter of the zones of inhibition was measured and recorded. Data were tabulated and statistical analysis was done using Statistical Package for the Social Science (16.0) version.

Results: Pediflor kids toothpaste® showed maximum antifungal activity and Aloe Dent children's toothpaste® showed minimum antifungal activity.

Conclusion: All brands of children's toothpaste show antifungal activity against Candida albicans.
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http://dx.doi.org/10.4103/JISPPD.JISPPD_3_20DOI Listing
July 2020

Comparative evaluation of three different toothpastes on remineralization potential of initial enamel lesions: A scanning electron microscopic study.

Indian J Dent Res 2020 Mar-Apr;31(2):217-223

Department of Pediatric and Preventive Dentistry, Kannur Dental College, Kannur, Kerala, India.

Background: The early enamel lesions are reversible as it is a process involving mineral transactions between the teeth and saliva.

Aim: To evaluate the efficiency of three different tooth pastes on remineralization potential of initial enamel lesions using Vickers Micro hardness Test and Scanning electron microscopy.

Materials And Methods: Artificial carious lesions were prepared in human enamel with demineralizing solution. The treatment agents included were Colgate sensitive plus toothpaste, Regenerate enamel science™ toothpaste, BioRepair toothpaste and control as Deionized water. All the samples were subjected to treatment solutions as per the pH cycling model for 12 days to simulate the daily oral environment's acid challenge. The remineralization parameters-surface hardness and surface roughness of enamel blocks were evaluated with Vickers indenter and Scanning electron microscope respectively. Statistical Analysis: ANOVA test was used to check mean differences between the groups. Post hoc analysis was done using Tukey's post hoc test. SEM images were graded according to Bonetti et al grading criteria.

Results: As per statistical analysis, maximum remineralization of enamel blocks occurred after applying Colgate Sensitive Plus tooth paste followed by BioRepair tooth paste and Regenerate enamel Science™ toothpaste. Least remineralization potential was shown by control group.

Conclusion: Colgate sensitive plus tooth paste with Pro Argin™ formula can be regarded as a potential remineralising agent. It can be concluded as a noninvasive means of managing early enamel carious lesions.
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http://dx.doi.org/10.4103/ijdr.IJDR_745_18DOI Listing
May 2020

Antimicrobial efficacy of medium chain fatty acids as root canal irrigants: An in vitro study.

J Indian Soc Pedod Prev Dent 2019 Jul-Sep;37(3):258-264

Department of Conservative Dentistry and Endodontics, PSM College of Dental Science and Research, Thrissur, Kerala, India.

Background: Enterococcus faecalis and Candida albicans are the microbes that are most resistant to elimination by disinfecting agents and are the causative agents for reinfection of the root canal treated teeth. Medium chain fatty acids (MCFAs), which are the main components of coconut oil, are proven antimicrobial agents. Thus, the aim of this study was to evaluate their antimicrobial efficacy against E. faecalis and C. albicans.

Methodology: Ninety extracted single-rooted mandibular premolar teeth were decoronated, biomechanically prepared, autoclaved, and divided into three groups (n = 30): Group A (inoculated with E. faecalis), Group B (inoculated with C. albicans), and Group C (control group). Each group was again subdivided into three groups (n = 10) and irrigated with lauric acid (LA), decanoic acid (DA), and octanoic acid, respectively, for 5 min. Paper point samples were taken from canal walls and transferred into Brain Heart Infusion broth and potato dextrose broth and placed in an incubator at 37°C. The appearance of tubidity was checked at 24, 48, 72, and 96 h using direct contact test. The data were then statistically analyzed using the analysis of variance and Tukey honestly significant difference post hoc tests.

Results: Among the three MCFAs, LA showed the maximum inhibitory against E. faecalis at 24 h and the inhibitory activity decreased considerably at 48, 72, and 96 h. DA was the most effective against C. albicans with a maximum inhibition at 48 h. DA also showed significant substantivity at 72 and 96 h.

Conclusion: Within the limitations of this study, it can be concluded that MCFAs show promising antimicrobial efficacy against E. faecalis and C. albicans.
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http://dx.doi.org/10.4103/JISPPD.JISPPD_63_19DOI Listing
November 2019

A Cross-sectional Study of the Prevalence of Dental Caries among 12- to 15-year-old Overweight Schoolchildren.

J Contemp Dent Pract 2016 Sep 1;17(9):750-754. Epub 2016 Sep 1.

Department of Preventive Dental Sciences, Prince Sattam Bin Abdulaziz University, AIKharj, Riyadh, Kingdom of Saudi Arabia.

Introduction: Overweight and obesity are growing health-related problems worldwide, and it is currently the most prevalent nutritional disorder among children and adolescents. The objective of this study was to assess the association between overweight and dental caries among 12- to 15-year-old schoolchildren in Mangaluru district, Karnataka, India.

Materials And Methods: Data were obtained from 2000 school-going children aged 12 to 15 years. The children were categorized as overweight and normal-weight group by assessing the body mass index (BMI). Body mass index was categorized using the classification system given by the International Obesity Task Force (IOTF) and obtained in units of kg/m. The dental caries was assessed by detection and was performed according to decayed, missing, and filled teeth (DMFT) index.

Results: Of the 2000 children examined, the mean BMI recorded was 26.87 ± 2.26 for the overweight children and 20.82 ± 1.48 for the normal-weight children. Even though the DMFT (3.90 ± 2.95) in the overweight children was slightly higher than the control group (3.36 ± 2.73), it was not statistically significant.

Conclusion: Within the confines of the present study, it can be concluded that there is no significant association between overweight and dental caries among the schoolchildren of Mangaluru district in Karnataka. Longitudinal studies are necessary to substantiate the possible relationships between dental caries and overweight in children. Knowledge of these relationships could lead to preventive health measures designed to reduce the prevalence of both obesity and dental caries.
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http://dx.doi.org/10.5005/jp-journals-10024-1924DOI Listing
September 2016

Comparison of Antimicrobial Activity of Chlorhexidine, Coconut Oil, Probiotics, and Ketoconazole on Candida albicans Isolated in Children with Early Childhood Caries: An In Vitro Study.

Scientifica (Cairo) 2016 14;2016:7061587. Epub 2016 Mar 14.

Department of Pedodontics, Kannur Dental College, Kerala 670612, India.

Background. Early childhood caries (ECC) is associated with early colonisation and high levels of cariogenic microorganisms. With C. albicans being one of those, there is a need to determine the effectiveness of various chemotherapeutic agents against it. The study is aimed at isolating Candida species in children with ECC and at studying the antifungal effect of coconut oil, probiotics, Lactobacillus, and 0.2% chlorhexidine on C. albicans in comparison with ketoconazole. Materials and Methods. Samples were collected using sterile cotton swabs, swabbed on the tooth surfaces from children with ECC of 3 to 6 yrs and streaked on Sabouraud dextrose agar (HI Media) plates and incubated in a 5% CO2 enriched atmosphere at 37°C for 24 hours. Candida was isolated and its susceptibility to probiotics, chlorhexidine, ketoconazole, and coconut oil was determined using Disc Diffusion method. Results. The mean zone of inhibition for chlorhexidine was 21.8 mm, whereas for coconut oil it was 16.8 mm, for probiotics it was 13.5 mm, and for ketoconazole it was 22.3 mm. The difference between the groups was not statistically significant (Chi-square value 7.42, P value 0.06). Conclusion. Chlorhexidine and coconut oil have shown significant antifungal activity which is comparable with ketoconazole.
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http://dx.doi.org/10.1155/2016/7061587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808662PMC
April 2016