Somsankar Dasgupta

Somsankar Dasgupta

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Somsankar Dasgupta

Somsankar Dasgupta

Publications by authors named "Somsankar Dasgupta"

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28Publications

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Potential therapeutic roles of retinoids for prevention of neuroinflammation and neurodegeneration in Alzheimer's disease.

Neural Regen Res 2019 Nov;14(11):1880-1892

Department of Pathology, Microbiology, and Immunology, University of South Carolina School of Medicine, Columbia, SC, USA.

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http://dx.doi.org/10.4103/1673-5374.259604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676868PMC
November 2019

Ceramide and Sphingosine Regulation of Myelinogenesis: Targeting Serine Palmitoyltransferase Using microRNA in Multiple Sclerosis.

Int J Mol Sci 2019 Oct 11;20(20). Epub 2019 Oct 11.

Department of Pathology, Microbiology, and Immunology, University of South Carolina School of Medicine, 6439 Garners Ferry Road, Columbia, SC 29209, USA.

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http://dx.doi.org/10.3390/ijms20205031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834223PMC
October 2019

Diverse Biological Functions of Sphingolipids in the CNS: Ceramide and Sphingosine Regulate Myelination in Developing Brain but Stimulate Demyelination during Pathogenesis of Multiple Sclerosis.

J Neurol Psychol 2017 Dec 23;5(1). Epub 2017 Dec 23.

Department of Pathology, Microbiology, and Immunology, University of South Carolina School of Medicine, USA.

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http://dx.doi.org/10.13188/2332-3469.1000035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190913PMC
December 2017

Insights into abnormal sphingolipid metabolism in multiple sclerosis: targeting ceramide biosynthesis as a unique therapeutic strategy.

Ther Targets Neurol Dis 2017 2;4. Epub 2017 Oct 2.

University of South Carolina School of Medicine, Department of Pathology, Microbiology, and Immunology, 6439 Garners Ferry Road, Columbia, SC 29209, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933878PMC
October 2017

Sphingosine Toxicity in EAE and MS: Evidence for Ceramide Generation via Serine-Palmitoyltransferase Activation.

Neurochem Res 2017 Oct 5;42(10):2755-2768. Epub 2017 May 5.

Institute of Molecular Medicine and Genetics, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.

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http://dx.doi.org/10.1007/s11064-017-2280-2DOI Listing
October 2017

Dietary Isomers of Sialyllactose Increase Ganglioside Sialic Acid Concentrations in the Corpus Callosum and Cerebellum and Modulate the Colonic Microbiota of Formula-Fed Piglets.

J Nutr 2016 Feb 23;146(2):200-8. Epub 2015 Dec 23.

Laboratory of Developmental Nutrition, Department of Animal Science, North Carolina State University, Raleigh, NC;

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http://dx.doi.org/10.3945/jn.115.220152DOI Listing
February 2016

Guggulsterone and bexarotene induce secretion of exosome-associated breast cancer resistance protein and reduce doxorubicin resistance in MDA-MB-231 cells.

Int J Cancer 2015 Oct 27;137(7):1610-20. Epub 2015 Apr 27.

Department of Neuroscience and Regenerative Medicine, Medical College of Georgia, Georgia Regents University, Augusta, GA.

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http://doi.wiley.com/10.1002/ijc.29542
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http://dx.doi.org/10.1002/ijc.29542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503537PMC
October 2015

Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration.

PLoS One 2014 20;9(10):e110119. Epub 2014 Oct 20.

Department of Neuroscience and Regenerative Medicine, Medical College of Georgia, Georgia Regents University, Augusta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110119PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203763PMC
July 2015

Phytoceramide in vertebrate tissues: one step chromatography separation for molecular characterization of ceramide species.

PLoS One 2013 29;8(11):e80841. Epub 2013 Nov 29.

Program in Developmental Neurobiology, Institute of Molecular Medicine and Genetics, Georgia Regents University, Augusta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080841PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843679PMC
September 2014

Exosome reduction in vivo is associated with lower amyloid plaque load in the 5XFAD mouse model of Alzheimer's disease.

Neurobiol Aging 2014 Aug 15;35(8):1792-800. Epub 2014 Feb 15.

Institute of Molecular Medicine and Genetics, Georgia Regents University, Augusta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035236PMC
August 2014

Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide.

Mol Biol Cell 2014 Jun 2;25(11):1715-29. Epub 2014 Apr 2.

Program in Developmental Neurobiology, Department of Neuroscience and Regenerative Medicine, Medical College of Georgia, Georgia Regents University, Augusta, GA 30912

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http://dx.doi.org/10.1091/mbc.E13-12-0730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038499PMC
June 2014

Characterization of an apical ceramide-enriched compartment regulating ciliogenesis.

Mol Biol Cell 2012 Aug 20;23(16):3156-66. Epub 2012 Jun 20.

Program in Developmental Neurobiology, Institute of Molecular Medicine and Genetics, School of Medicine, Georgia Health Sciences University, Augusta, GA 30912, USA.

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http://www.molbiolcell.org/content/23/16/3156.full.pdf
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http://www.molbiolcell.org/cgi/doi/10.1091/mbc.E12-02-0079
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http://dx.doi.org/10.1091/mbc.E12-02-0079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418310PMC
August 2012

Sulfoglucuronosyl paragloboside promotes endothelial cell apoptosis in inflammation: elucidation of a novel glycosphingolipid-signaling pathway.

J Neurochem 2011 Nov 11;119(4):749-59. Epub 2011 Oct 11.

Institute of Molecular Medicine and Genetics and Institute of Neuroscience, Medical College of Georgia, Georgia Health Sciences University, Augusta, Georgia 30912, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07483.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218081PMC
November 2011

Novel myelin penta- and hexa-acetyl-galactosyl-ceramides: structural characterization and immunoreactivity in cerebrospinal fluid.

J Lipid Res 2010 Jun 12;51(6):1394-406. Epub 2010 Feb 12.

Department of Neurology, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA, USA.

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http://dx.doi.org/10.1194/jlr.M001396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035502PMC
June 2010

Sulfoglucuronosyl paragloboside is a ligand for T cell adhesion: regulation of sulfoglucuronosyl paragloboside expression via nuclear factor kappaB signaling.

J Neurosci Res 2009 Dec;87(16):3591-9

Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia 30912, USA.

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http://dx.doi.org/10.1002/jnr.22153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690938PMC
December 2009

Structural analysis of novel bioactive acylated steryl glucosides in pre-germinated brown rice bran.

J Lipid Res 2008 Oct 27;49(10):2188-96. Epub 2008 Jun 27.

Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, USA.

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http://dx.doi.org/10.1194/jlr.M800257-JLR200DOI Listing
October 2008

Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain development.

J Neurochem 2008 Jul 2;106(2):718-33. Epub 2008 May 2.

Program in Developmental Neurobiology, Institute of Molecular Medicine and Genetics, School of Medicine, Medical College of Georgia, Augusta, Georgia, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2008.05451.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812674PMC
July 2008

Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes.

Glia 2008 Mar;56(4):449-56

Program in Developmental Neurobiology, Institute of Molecular Medicine and Genetics, School of Medicine, Medical College of Georgia, Augusta, GA 30912, USA.

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http://dx.doi.org/10.1002/glia.20626DOI Listing
March 2008

Characterization of novel myelin components 3-O-acetyl-sphingosine galactosylceramides by electrospray ionization Q-TOF MS and MS/CID-MS of Li+ adducts.

J Mass Spectrom 2007 May;42(5):598-620

Department of Chemistry, University of New Hampshire, G229 Parsons Hall, Durham, NH 03824-3598, USA.

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http://dx.doi.org/10.1002/jms.1190DOI Listing
May 2007

Inhibition of neuronal migration by JONES antibody is independent of 9-O-acetyl GD3 in GD3-synthase knockout mice.

J Neurosci Res 2007 May;85(7):1381-90

Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia 30912, USA.

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http://dx.doi.org/10.1002/jnr.21264DOI Listing
May 2007

Development and characterization of a novel anti-ceramide antibody.

J Lipid Res 2007 Apr 8;48(4):968-75. Epub 2007 Jan 8.

School of Medicine, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, USA.

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http://dx.doi.org/10.1194/jlr.D600043-JLR200DOI Listing
April 2007

Tumor necrosis factor-alpha up-regulates glucuronosyltransferase gene expression in human brain endothelial cells and promotes T-cell adhesion.

J Neurosci Res 2007 Apr;85(5):1086-94

Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia 30912, USA.

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http://dx.doi.org/10.1002/jnr.21214DOI Listing
April 2007

Lipids isolated from bone induce the migration of human breast cancer cells.

J Lipid Res 2006 Apr 26;47(4):724-33. Epub 2006 Jan 26.

Institute of Molecular Medicine and Genetics,School of Medicine, Medical College of Georgia, Augusta, GA 30912, USA.

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http://dx.doi.org/10.1194/jlr.M500473-JLR200DOI Listing
April 2006

Highly active antiretroviral therapy and human immunodeficiency virus encephalitis.

Ann Neurol 2005 Jun;57(6):795-803

Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1002/ana.20479DOI Listing
June 2005

Lack of apparent neurological abnormalities in rabbits sensitized by gangliosides.

Neurochem Res 2004 Nov;29(11):2147-52

Program of Developmental Neurobiology, Institute of Molecular Medicine and Genetics, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, USA.

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http://dx.doi.org/10.1007/s11064-004-6888-7DOI Listing
November 2004

3-O-acetyl-sphingosine-series myelin glycolipids: characterization of novel 3-O-acetyl-sphingosine galactosylceramide.

J Lipid Res 2002 May;43(5):751-61

Department of Neurology, Medical University of South Carolina, 96 Jonathan Lucas Street, P.O. Box 250606, Charleston, SC 29425, USA.

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May 2002