Somnath Dutta

Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment.

J Biol Chem 2020 Nov 23;296:100025. Epub 2020 Nov 23.

Molecular Biophysics Unit (MBU), Indian Institute of Science, Bengaluru, India; Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India. Electronic address:

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November 2020

Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment.

J Biol Chem 2020 Nov 5. Epub 2020 Nov 5.

Molecular Biophysics Unit (MBU), Indian Institute of Science, Bangalore, India.

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November 2020

Tyrosine in the hinge region of the pore-forming motif regulates oligomeric β-barrel pore formation by Vibrio cholerae cytolysin.

Authors:

Anish Kumar Mondal Paras Verma Nayanika Sengupta Somnath Dutta Shashi Bhushan Pandit Kausik Chattopadhyay

Mol Microbiol 2020 Oct 21. Epub 2020 Oct 21.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, India.

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October 2020

N-Terminal Region of Thermostable Direct Hemolysin Regulates the Membrane-Damaging Action of the Toxin.

Authors:

Nidhi Kundu Pratima Verma Anil Kumar Vinica Dhar Somnath Dutta Kausik Chattopadhyay

Biochemistry 2020 02 20;59(4):605-614. Epub 2019 Dec 20.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences , Indian Institute of Science Education and Research Mohali , Sector 81, SAS Nagar, Manauli , Mohali 140306 , Punjab , India.

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February 2020

Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms.

Authors:

Eshan Ghosh Hemlata Dwivedi Mithu Baidya Ashish Srivastava Punita Kumari Tomek Stepniewski Hee Ryung Kim Mi-Hye Lee Jaana van Gastel Madhu Chaturvedi Debarati Roy Shubhi Pandey Jagannath Maharana Ramon Guixà-González Louis M Luttrell Ka Young Chung Somnath Dutta Jana Selent Arun K Shukla

Cell Rep 2019 09;28(13):3287-3299.e6

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India. Electronic address:

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September 2019

Development of mCherry tagged UdgX as a highly sensitive molecular probe for specific detection of uracils in DNA.

Authors:

Madhurima Datta Shashanka Aroli Kapudeep Karmakar Somnath Dutta Dipshikha Chakravortty Umesh Varshney

Biochem Biophys Res Commun 2019 10 9;518(1):38-43. Epub 2019 Aug 9.

Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, 560012, India; Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, 560064, India. Electronic address:

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October 2019

Author Correction: Structural insights into the activation of metabotropic glutamate receptors.

Authors:

Antoine Koehl Hongli Hu Dan Feng Bingfa Sun Yan Zhang Michael J Robertson Matthew Chu Tong Sun Kobilka Toon Laeremans Jan Steyaert Jeffrey Tarrasch Somnath Dutta Rasmus Fonseca William I Weis Jesper M Mathiesen Georgios Skiniotis Brian K Kobilka

Nature 2019 Mar;567(7747):E10

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

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March 2019

Structural insights into the activation of metabotropic glutamate receptors.

Authors:

Antoine Koehl Hongli Hu Dan Feng Bingfa Sun Yan Zhang Michael J Robertson Matthew Chu Tong Sun Kobilka Toon Laeremans Jan Steyaert Jeffrey Tarrasch Somnath Dutta Rasmus Fonseca William I Weis Jesper M Mathiesen Georgios Skiniotis Brian K Kobilka

Nature 2019 02 23;566(7742):79-84. Epub 2019 Jan 23.

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

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February 2019

Dodecameric structure of a small heat shock protein from Mycobacterium marinum M.

Authors:

Spraha Bhandari Sreeparna Biswas Anuradha Chaudhary Somnath Dutta Kaza Suguna

Proteins 2019 05 22;87(5):365-379. Epub 2019 Jan 22.

Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.

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May 2019

An HIV-1 Broadly Neutralizing Antibody from a Clade C-Infected Pediatric Elite Neutralizer Potently Neutralizes the Contemporaneous and Autologous Evolving Viruses.

Authors:

Sanjeev Kumar Harekrushna Panda Muzamil Ashraf Makhdoomi Nitesh Mishra Haaris Ahsan Safdari Himanshi Chawla Heena Aggarwal Elluri Seetharami Reddy Rakesh Lodha Sushil Kumar Kabra Anmol Chandele Somnath Dutta Kalpana Luthra

J Virol 2019 02 5;93(4). Epub 2019 Feb 5.

Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India

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February 2019

Illuminating GPCR Signaling by Cryo-EM.

Authors:

Haaris Ahsan Safdari Shubhi Pandey Arun K Shukla Somnath Dutta

Trends Cell Biol 2018 08 23;28(8):591-594. Epub 2018 Jun 23.

Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India. Electronic address:

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August 2018

The minimal ESCRT machinery of Giardia lamblia has altered inter-subunit interactions within the ESCRT-II and ESCRT-III complexes.

Authors:

Nabanita Saha Somnath Dutta Shankari P Datta Srimonti Sarkar

Eur J Cell Biol 2018 Jan 6;97(1):44-62. Epub 2017 Dec 6.

Department of Biochemistry, Bose Institute, P 1/12 CIT Road Scheme VII M, Kolkata 700054, West Bengal, India. Electronic address:

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January 2018

The Vps13p-Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion.

Authors:

Mithu De Austin N Oleskie Mariam Ayyash Somnath Dutta Liliya Mancour Mohamed E Abazeed Eddy J Brace Georgios Skiniotis Robert S Fuller

J Cell Biol 2017 02 25;216(2):425-439. Epub 2017 Jan 25.

Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109

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February 2017

Structure-based Design of Cyclically Permuted HIV-1 gp120 Trimers That Elicit Neutralizing Antibodies.

Authors:

Sannula Kesavardhana Raksha Das Michael Citron Rohini Datta Linda Ecto Nonavinakere Seetharam Srilatha Daniel DiStefano Ryan Swoyer Joseph G Joyce Somnath Dutta Celia C LaBranche David C Montefiori Jessica A Flynn Raghavan Varadarajan

J Biol Chem 2017 Jan 22;292(1):278-291. Epub 2016 Nov 22.

From the Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India,

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January 2017

Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly.

Authors:

Kai Xu Yee-Peng Chan Birgit Bradel-Tretheway Zeynep Akyol-Ataman Yongqun Zhu Somnath Dutta Lianying Yan YanRu Feng Lin-Fa Wang Georgios Skiniotis Benhur Lee Z Hong Zhou Christopher C Broder Hector C Aguilar Dimitar B Nikolov

PLoS Pathog 2015 Dec 8;11(12):e1005322. Epub 2015 Dec 8.

Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.

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December 2015

Significantly Diverged Did2/Vps46 Orthologues from the Protozoan Parasite Giardia lamblia.

Authors:

Somnath Dutta Nabanita Saha Atrayee Ray Srimonti Sarkar

Curr Microbiol 2015 Sep 12;71(3):333-40. Epub 2015 Jun 12.

Department of Biochemistry (Room 226), Bose Institute, Centenary Campus, P 1/12 C.I.T. Scheme VII M, Kolkata, 700054, West Bengal, India.

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September 2015

Visualization of an N-terminal fragment of von Willebrand factor in complex with factor VIII.

Authors:

Andrew Yee Austin N Oleskie Anne M Dosey Colin A Kretz Robert D Gildersleeve Somnath Dutta Min Su David Ginsburg Georgios Skiniotis

Blood 2015 Aug 11;126(8):939-42. Epub 2015 Jun 11.

Life Sciences Institute, Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI.

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August 2015

Structural rearrangements of a polyketide synthase module during its catalytic cycle.

Authors:

Jonathan R Whicher Somnath Dutta Douglas A Hansen Wendi A Hale Joseph A Chemler Annie M Dosey Alison R H Narayan Kristina Håkansson David H Sherman Janet L Smith Georgios Skiniotis

Nature 2014 Jun 18;510(7506):560-4. Epub 2014 Jun 18.

1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA [2] Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

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June 2014

Structure of a modular polyketide synthase.

Authors:

Somnath Dutta Jonathan R Whicher Douglas A Hansen Wendi A Hale Joseph A Chemler Grady R Congdon Alison R H Narayan Kristina Håkansson David H Sherman Janet L Smith Georgios Skiniotis

Nature 2014 Jun 18;510(7506):512-7. Epub 2014 Jun 18.

1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA [2] Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

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June 2014

Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system.

Authors:

David L Akey W Clay Brown Somnath Dutta Jamie Konwerski Joyce Jose Thomas J Jurkiw James DelProposto Craig M Ogata Georgios Skiniotis Richard J Kuhn Janet L Smith

Science 2014 Feb 6;343(6173):881-5. Epub 2014 Feb 6.

Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.

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February 2014

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