Soldano Ferrone

Soldano Ferrone

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Soldano Ferrone

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In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab.

Authors:
Sara Caratelli Roberto Arriga Tommaso Sconocchia Alessio Ottaviani Giulia Lanzilli Donatella Pastore Carlo Cenciarelli Adriano Venditti Maria Ilaria Del Principe Davide Lauro Elisa Landoni Hongwei Du Barbara Savoldo Soldano Ferrone Gianpietro Dotti Giuseppe Sconocchia

Int J Cancer 2020 Jan 12;146(1):236-247. Epub 2019 Oct 12.

Department of Biomedical Sciences, Institute of Translational Pharmacology, CNR, Rome, Italy.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32663
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http://dx.doi.org/10.1002/ijc.32663DOI Listing
January 2020

HLA Class I Antigen Processing Machinery Defects in Cancer Cells-Frequency, Functional Significance, and Clinical Relevance with Special Emphasis on Their Role in T Cell-Based Immunotherapy of Malignant Disease.

Authors:
Barbara Seliger Soldano Ferrone

Methods Mol Biol 2020 ;2055:325-350

Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9773-2_15DOI Listing
January 2020

Computationally Guided Design of Single-Chain Variable Fragment Improves Specificity of Chimeric Antigen Receptors.

Authors:
Andrey Krokhotin Hongwei Du Koichi Hirabayashi Konstantin Popov Tomohiro Kurokawa Xinhui Wan Soldano Ferrone Gianpietro Dotti Nikolay V Dokholyan

Mol Ther Oncolytics 2019 Dec 31;15:30-37. Epub 2019 Aug 31.

Departments of Pharmacology and Biochemistry & Molecular Biology, Penn State College of Medicine, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1016/j.omto.2019.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804740PMC
December 2019

B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres.

Authors:
Dean Nehama Natalia Di Ianni Silvia Musio Hongwei Du Monica Patané Bianca Pollo Gaetano Finocchiaro James J H Park Denise E Dunn Drake S Edwards Jeffrey S Damrauer Hannah Hudson Scott R Floyd Soldano Ferrone Barbara Savoldo Serena Pellegatta Gianpietro Dotti

EBioMedicine 2019 Sep 26;47:33-43. Epub 2019 Aug 26.

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964193055
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http://dx.doi.org/10.1016/j.ebiom.2019.08.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796553PMC
September 2019

CD16-158-valine chimeric receptor T cells overcome the resistance of KRAS-mutated colorectal carcinoma cells to cetuximab.

Authors:
Roberto Arriga Sara Caratelli Giulia Lanzilli Alessio Ottaviani Carlo Cenciarelli Tommaso Sconocchia Giulio C Spagnoli Giandomenica Iezzi Mario Roselli Davide Lauro Andrea Coppola Gianpietro Dotti Soldano Ferrone Giuseppe Sconocchia

Int J Cancer 2019 Aug 9. Epub 2019 Aug 9.

Institute of Translational Pharmacology, CNR, Rome, Italy.

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http://dx.doi.org/10.1002/ijc.32618DOI Listing
August 2019

Potential Role of HLA Class I Antigens in the Glycolytic Metabolism and Motility of Melanoma Cells.

Authors:
Silvia Peppicelli Jessica Ruzzolini Elena Andreucci Francesca Bianchini Filippos Kontos Teppei Yamada Soldano Ferrone Lido Calorini

Cancers (Basel) 2019 Aug 26;11(9). Epub 2019 Aug 26.

Department of Experimental and Clinical Biomedical Sciences "Mario Serio", Section of Experimental Pathology and Oncology, Viale G.B. Morgagni, 50-50134, Florence, Italy.

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http://dx.doi.org/10.3390/cancers11091249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770395PMC
August 2019

Decreased expression of mitochondrial miR-5787 contributes to chemoresistance by reprogramming glucose metabolism and inhibiting MT-CO3 translation.

Authors:
Weixiong Chen Peng Wang Yingjuan Lu Tingting Jin Xinyuan Lei Mo Liu Peilin Zhuang Junkun Liao Zhaoyu Lin Bowen Li Yu Peng Guokai Pan Xiaobin Lv Hanqing Zhang Zhanpeng Ou Shule Xie Xinyu Lin Sheng Sun Soldano Ferrone Bakhos A Tannous Yi Ruan Jinsong Li Song Fan

Theranostics 2019 12;9(20):5739-5754. Epub 2019 Aug 12.

Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation of Sun Yat-Sen Memorial Hospital, Guangzhou 510120, China.

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http://dx.doi.org/10.7150/thno.37556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735381PMC
August 2019

Translational Research in Cutaneous Melanoma: New Therapeutic Perspectives.

Authors:
Antonio Marra Cristina R Ferrone Celeste Fusciello Giosue Scognamiglio Soldano Ferrone Stefano Pepe Francesco Perri Francesco Sabbatino

Anticancer Agents Med Chem 2018 ;18(2):166-181

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, United States.

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http://dx.doi.org/10.2174/1871520618666171219115335DOI Listing
July 2019

Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th-1 December 1st, 2018, Naples, Italy).

Authors:
Paolo A Ascierto Sanjiv S Agarwala Gerardo Botti Alfredo Budillon Michael A Davies Reinhard Dummer Marc Ernstoff Soldano Ferrone Silvia Formenti Thomas F Gajewski Claus Garbe Omid Hamid Roger S Lo Jason J Luke Oliver Michielin Giuseppe Palmieri Laurence Zitvogel Francesco M Marincola Giuseppe Masucci Corrado Caracò Magdalena Thurin Igor Puzanov

J Transl Med 2019 Jul 22;17(1):234. Epub 2019 Jul 22.

Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

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https://translational-medicine.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12967-019-1979-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647284PMC
July 2019

High IDO1 Expression Is Associated with Poor Outcome in Patients with Anal Cancer Treated with Definitive Chemoradiotherapy.

Authors:
Devarati Mitra Nora K Horick Diane G Brackett Kent W Mouw Jason L Hornick Soldano Ferrone Theodore S Hong Harvey Mamon Jeffrey W Clark Aparna R Parikh Jill N Allen David P Ryan David T Ting Vikram Deshpande Jennifer Y Wo

Oncologist 2019 Jun 12;24(6):e275-e283. Epub 2019 Feb 12.

Department of Radiation Oncology, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, USA

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http://dx.doi.org/10.1634/theoncologist.2018-0794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656510PMC
June 2019

Long Noncoding RNA MPRL Promotes Mitochondrial Fission and Cisplatin Chemosensitivity via Disruption of Pre-miRNA Processing.

Authors:
Tian Tian Xiaobin Lv Guokai Pan Yingjuan Lu Weixiong Chen Wang He Xinyuan Lei Hanqing Zhang Mo Liu Sheng Sun Zhanpeng Ou Xinyu Lin Lei Cai Lile He Zhiming Tu Xinhui Wang Bakhos A Tannous Soldano Ferrone Jinsong Li Song Fan

Clin Cancer Res 2019 Jun 18;25(12):3673-3688. Epub 2019 Mar 18.

Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Guangzhou, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-2739DOI Listing
June 2019

Identification of CSPG4 as a promising target for translational combinatorial approaches in osteosarcoma.

Authors:
Federica Riccardo Lidia Tarone Selina Iussich Davide Giacobino Maddalena Arigoni Federica Sammartano Emanuela Morello Marina Martano Francesca Gattino Raffaella De Maria Soldano Ferrone Paolo Buracco Federica Cavallo

Ther Adv Med Oncol 2019 6;11:1758835919855491. Epub 2019 Jun 6.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1177/1758835919855491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557023PMC
June 2019

Role of Tumor-Associated Macrophages in the Clinical Course of Pancreatic Neuroendocrine Tumors (PanNETs).

Authors:
Lei Cai Theodoros Michelakos Vikram Deshpande Kshitij S Arora Teppei Yamada David T Ting Marty S Taylor Carlos Fernandez-Del Castillo Andrew L Warshaw Keith D Lillemoe Soldano Ferrone Cristina R Ferrone

Clin Cancer Res 2019 Apr 22;25(8):2644-2655. Epub 2019 Jan 22.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582654PMC
April 2019

Mitochondrial miRNA Determines Chemoresistance by Reprogramming Metabolism and Regulating Mitochondrial Transcription.

Authors:
Song Fan Tian Tian Weixiong Chen Xiaobin Lv Xinyuan Lei Hanqing Zhang Sheng Sun Lei Cai Guokai Pan Lile He Zhanpeng Ou Xinyu Lin Xinhui Wang Matthew Francis Perez Zhiming Tu Soldano Ferrone Bakhos A Tannous Jinsong Li

Cancer Res 2019 03 18;79(6):1069-1084. Epub 2019 Jan 18.

Department of Oral and Maxillofacial Surgery, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-2505DOI Listing
March 2019

Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells.

Authors:
Hongwei Du Koichi Hirabayashi Sarah Ahn Nancy Porterfield Kren Stephanie Ann Montgomery Xinhui Wang Karthik Tiruthani Bhalchandra Mirlekar Daniel Michaud Kevin Greene Silvia Gabriela Herrera Yang Xu Chuang Sun Yuhui Chen Xingcong Ma Cristina Rosa Ferrone Yuliya Pylayeva-Gupta Jen Jen Yeh Rihe Liu Barbara Savoldo Soldano Ferrone Gianpietro Dotti

Cancer Cell 2019 02;35(2):221-237.e8

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108193000
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http://dx.doi.org/10.1016/j.ccell.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645919PMC
February 2019

B7-H3-targeted radioimmunotherapy of human cancer.

Authors:
Benjamin B Kasten Soldano Ferrone Kurt R Zinn Donald J Buchsbaum

Curr Med Chem 2019 Feb 28. Epub 2019 Feb 28.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama. United States.

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http://dx.doi.org/10.2174/0929867326666190228120908DOI Listing
February 2019

Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition.

Authors:
Rosa Sottile Giorgia Federico Cinzia Garofalo Rossana Tallerico Maria Concetta Faniello Barbara Quaresima Costanza Maria Cristiani Maddalena Di Sanzo Gianni Cuda Valeria Ventura Arnika Kathleen Wagner Gianluca Contrò Nicola Perrotti Elio Gulletta Soldano Ferrone Klas Kärre Francesco Saverio Costanzo Francesca Carlomagno Ennio Carbone

Front Immunol 2019 26;10:224. Epub 2019 Feb 26.

Tumor Immunology and Immunopathology Laboratory, Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.

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http://dx.doi.org/10.3389/fimmu.2019.00224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404638PMC
February 2019

The Humoral Theory of Transplantation.

Authors:
Mepur H Ravindranath Junchao Cai Soldano Ferrone Frans H J Claas Senthamil R Selvan

J Immunol Res 2017;2017:5935123. Epub 2017 Aug 8.

Omni Array Biotechnology, Rockville, MD 20855, USA.

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http://dx.doi.org/10.1155/2017/5935123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591932PMC
January 2019

Novel ANO5 mutation c.1067G>T (p.C356F) identified by whole genome sequencing in a big family with atypical gnathodiaphyseal dysplasia.

Authors:
Binghui Zeng Junkun Liao Hanqing Zhang Sha Fu Weixiong Chen Guokai Pan Qunxing Li Weiliang Chen Soldano Ferrone Binghao Wu Sheng Sun Jiali Hu Michael Ho-Young Ahn Zhaoyu Lin Dongsheng Yu Zhanpeng Ou Xinhui Wang Fengbo Mo Nasi Huang James A Hamilton Jinsong Li Song Fan

Head Neck 2019 Jan 15;41(1):230-238. Epub 2018 Dec 15.

Department of Oral and Maxillofacial Surgery, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, China.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/hed.25516
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http://dx.doi.org/10.1002/hed.25516DOI Listing
January 2019

Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy.

Authors:
Michele Maio George Coukos Soldano Ferrone Bernard A Fox Wolf H Fridman Patrick L Garcia Michael Lahn Olivier Provendier Vincenzo Russo Dominik Rüttinger Aiman Shalabi Zlatko Trajanoski Jean Viallet Jedd D Wolchok Ramy Ibrahim

Cancer Immunol Immunother 2019 Jan 18;68(1):1-9. Epub 2018 Dec 18.

Parker Institute for Cancer Immunotherapy, 1 Letterman Drive, San Francisco, CA, 94129, USA.

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http://dx.doi.org/10.1007/s00262-018-2285-yDOI Listing
January 2019

The role of cancer stem cells in the modulation of anti-tumor immune responses.

Authors:
Cristina Maccalli Kakil Ibrahim Rasul Mamoun Elawad Soldano Ferrone

Semin Cancer Biol 2018 12 24;53:189-200. Epub 2018 Sep 24.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S1044579X183004
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http://dx.doi.org/10.1016/j.semcancer.2018.09.006DOI Listing
December 2018

Resistance to anti-PD-1-based immunotherapy in basal cell carcinoma: a case report and review of the literature.

Authors:
Francesco Sabbatino Antonio Marra Luigi Liguori Giosuè Scognamiglio Celeste Fusciello Gerardo Botti Soldano Ferrone Stefano Pepe

J Immunother Cancer 2018 11 20;6(1):126. Epub 2018 Nov 20.

Medical Oncology Unit, Department of Medicine, Surgery and Dentistry, University of Salerno, 84131, Salerno, Italy.

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http://dx.doi.org/10.1186/s40425-018-0439-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247622PMC
November 2018

Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours.

Authors:
Aurélie Durgeau Yasemin Virk Gwendoline Gros Elodie Voilin Stéphanie Corgnac Fayçal Djenidi Jérôme Salmon Julien Adam Vincent de Montpréville Pierre Validire Soldano Ferrone Salem Chouaib Alexander Eggermont Jean-Charles Soria François Lemonnier Eric Tartour Nathalie Chaput Benjamin Besse Fathia Mami-Chouaib

Nat Commun 2018 11 30;9(1):5097. Epub 2018 Nov 30.

INSERM UMR 1186, Integrative Tumour Immunology and Genetic Oncology, Gustave Roussy, EPHE, PSL, Fac. de Médecine, Univ. Paris-Sud, Université Paris-Saclay, 94805, Villejuif, France.

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http://www.nature.com/articles/s41467-018-07603-1
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http://dx.doi.org/10.1038/s41467-018-07603-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269466PMC
November 2018

Significance of the intraindividual variability of HLA IgG antibodies in renal disease patients observed with different beadsets monitored with two different secondary antibodies on a Luminex platform.

Authors:
Mepur H Ravindranath Edward J Filippone Grace Mahowald Carly Callender Adarsh Babu Susan Saidman Soldano Ferrone

Immunol Res 2018 10;66(5):584-604

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s12026-018-9027-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244961PMC
October 2018

Molecular and Functional Profiles of Exosomes From HPV(+) and HPV(-) Head and Neck Cancer Cell Lines.

Authors:
Sonja Ludwig Priyanka Sharma Marie-Nicole Theodoraki Monika Pietrowska Saigopalakrishna S Yerneni Stephan Lang Soldano Ferrone Theresa L Whiteside

Front Oncol 2018 12;8:445. Epub 2018 Oct 12.

UPMC Hillman Cancer Center, Pittsburgh, PA, United States.

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https://www.frontiersin.org/article/10.3389/fonc.2018.00445/
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http://dx.doi.org/10.3389/fonc.2018.00445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194188PMC
October 2018

Corrigendum to Monitoring native HLA-I trimer specific antibodies in Luminex multiplex single antigen bead assay: Evaluation of beadsets from different manufacturers Journal of Immunological Methods, Volume 450, Year (2017), start page 73, end page 80.

Authors:
Mepur H Ravindranath Vadim Jucaud Soldano Ferrone

J Immunol Methods 2018 Sep;460:125

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.1016/j.jim.2018.07.008DOI Listing
September 2018

Risk Prediction Model for Cisplatin-Associated Acute Kidney Injury.

Authors:
Tomohiro Kurokawa Giichiro Tsurita Tetsuya Tanimoto Teppei Yamada Soldano Ferrone

J Clin Oncol 2018 08 29;36(23):2453-2454. Epub 2018 Jun 29.

Tomohiro Kurokawa, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Giichiro Tsurita, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Tetsuya Tanimoto, Jyoban Hospital of Tokiwa Foundation, Fukushima, Japan; and Teppei Yamada and Soldano Ferrone, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2018.77.8761DOI Listing
August 2018

Methods for improving the immunogenicity and efficacy of cancer vaccines.

Authors:
Lorenzo Pilla Soldano Ferrone Cristina Maccalli

Expert Opin Biol Ther 2018 07 17;18(7):765-784. Epub 2018 Jun 17.

c Clinical Research Center, Division of Translational Medicine , Sidra Medicine , Doha , Qatar.

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http://dx.doi.org/10.1080/14712598.2018.1485649DOI Listing
July 2018

Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy).

Authors:
Paolo A Ascierto Igor Puzanov Sanjiv S Agarwala Carlo Bifulco Gerardo Botti Corrado Caracò Gennaro Ciliberto Michael A Davies Reinhard Dummer Soldano Ferrone Thomas F Gajewski Claus Garbe Jason J Luke Francesco M Marincola Giuseppe Masucci Janice M Mehnert Nicola Mozzillo Giuseppe Palmieri Michael A Postow Stephen P Schoenberger Ena Wang Magdalena Thurin

J Transl Med 2018 07 21;16(1):207. Epub 2018 Jul 21.

Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, NCI, NIH, Rockville, MD, USA.

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http://dx.doi.org/10.1186/s12967-018-1568-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054754PMC
July 2018

Defective HLA class I antigen processing machinery in cancer.

Authors:
Lei Cai Theodoros Michelakos Teppei Yamada Song Fan Xinhui Wang Joseph H Schwab Cristina R Ferrone Soldano Ferrone

Cancer Immunol Immunother 2018 06 27;67(6):999-1009. Epub 2018 Feb 27.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s00262-018-2131-2DOI Listing
June 2018

Corrigendum to 'Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models' [Nucl Med Biol 58 (2018) 67-73].

Authors:
Benjamin B Kasten Abhishek Gangrade Harrison Kim Jinda Fan Soldano Ferrone Cristina R Ferrone Kurt R Zinn Donald J Buchsbaum

Nucl Med Biol 2018 06 25;61:71. Epub 2018 Apr 25.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL, United States.

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http://dx.doi.org/10.1016/j.nucmedbio.2018.03.004DOI Listing
June 2018

Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models.

Authors:
Benjamin B Kasten Abhishek Gangrade Harrison Kim Jinda Fan Soldano Ferrone Cristina R Ferrone Kurt R Zinn Donald J Buchsbaum

Nucl Med Biol 2018 03 24;58:67-73. Epub 2017 Dec 24.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL, United States.

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http://dx.doi.org/10.1016/j.nucmedbio.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817013PMC
March 2018

Pb-Labeled Antibody 225.28 Targeted to Chondroitin Sulfate Proteoglycan 4 for Triple-Negative Breast Cancer Therapy in Mouse Models.

Authors:
Benjamin B Kasten Patsy G Oliver Harrison Kim Jinda Fan Soldano Ferrone Kurt R Zinn Donald J Buchsbaum

Int J Mol Sci 2018 Mar 21;19(4). Epub 2018 Mar 21.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.3390/ijms19040925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979285PMC
March 2018

HLA class I antigen processing machinery (APM) component expression and PD-1:PD-L1 pathway activation in HIV-infected head and neck cancers.

Authors:
Sara I Pai J Jack Lee Thomas E Carey William H Westra Soldano Ferrone Charles Moore Marina B Mosunjac Dong M Shin Robert L Ferris

Oral Oncol 2018 02 28;77:92-97. Epub 2017 Dec 28.

Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2017.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786382PMC
February 2018

Constitutive and TNFα-inducible expression of chondroitin sulfate proteoglycan 4 in glioblastoma and neurospheres: Implications for CAR-T cell therapy.

Authors:
Serena Pellegatta Barbara Savoldo Natalia Di Ianni Cristina Corbetta Yuhui Chen Monica Patané Chuang Sun Bianca Pollo Soldano Ferrone Francesco DiMeco Gaetano Finocchiaro Gianpietro Dotti

Sci Transl Med 2018 02;10(430)

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1126/scitranslmed.aao2731DOI Listing
February 2018

Immunoaffinity-based isolation of melanoma cell-derived exosomes from plasma of patients with melanoma.

Authors:
Priyanka Sharma Sonja Ludwig Laurent Muller Chang Sook Hong John M Kirkwood Soldano Ferrone Theresa L Whiteside

J Extracell Vesicles 2018 15;7(1):1435138. Epub 2018 Feb 15.

Department of Pathology, University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1080/20013078.2018.1435138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827723PMC
February 2018

Immune Surveillance Plays a Role in Locally Aggressive Giant Cell Lesions of Bone.

Authors:
Ahmad Al-Sukaini Francis J Hornicek Zachary S Peacock Leonard B Kaban Soldano Ferrone Joseph H Schwab

Clin Orthop Relat Res 2017 Dec 19;475(12):3071-3081. Epub 2017 Jul 19.

Department of Orthopaedic Surgery, Massachusetts General Hospital-Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s11999-017-5451-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670060PMC
December 2017

Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer.

Authors:
Scott Gettinger Jungmin Choi Katherine Hastings Anna Truini Ila Datar Ryan Sowell Anna Wurtz Weilai Dong Guoping Cai Mary Ann Melnick Victor Y Du Joseph Schlessinger Sarah B Goldberg Anne Chiang Miguel F Sanmamed Ignacio Melero Jackeline Agorreta Luis M Montuenga Richard Lifton Soldano Ferrone Paula Kavathas David L Rimm Susan M Kaech Kurt Schalper Roy S Herbst Katerina Politi

Cancer Discov 2017 12 12;7(12):1420-1435. Epub 2017 Oct 12.

Department of Medicine (Section of Medical Oncology), Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718941PMC
December 2017

Overexpression of miR-489 enhances efficacy of 5-fluorouracil-based treatment in breast cancer stem cells by targeting XIAP.

Authors:
Xuedong Wang Xinguo Wang Juan Gu Ming Zhou Zhimin He Xinhui Wang Soldano Ferrone

Oncotarget 2017 Dec 6;8(69):113837-113846. Epub 2017 Dec 6.

Department of Medical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.18632/oncotarget.22985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768367PMC
December 2017

Monitoring native HLA-I trimer specific antibodies in Luminex multiplex single antigen bead assay: Evaluation of beadsets from different manufacturers.

Authors:
Mepur H Ravindranath Vadim Jucaud Soldano Ferrone

J Immunol Methods 2017 11 4;450:73-80. Epub 2017 Aug 4.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

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November 2017

A novel chemoradiation targeting stem and nonstem pancreatic cancer cells by repurposing disulfiram.

Authors:
Juan Cong Yangyang Wang Xiao Zhang Nan Zhang Ling Liu Klara Soukup Theodoros Michelakos Theodore Hong Albert DeLeo Lei Cai Francesco Sabbatino Soldano Ferrone Hang Lee Vera Levina Bryan Fuchs Kenneth Tanabe Keith Lillemoe Cristina Ferrone Xinhui Wang

Cancer Lett 2017 11 30;409:9-19. Epub 2017 Aug 30.

Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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November 2017

Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016.

Authors:
Paolo A Ascierto Sanjiv S Agarwala Gennaro Ciliberto Sandra Demaria Reinhard Dummer Connie P M Duong Soldano Ferrone Silvia C Formenti Claus Garbe Ruth Halaban Samir Khleif Jason J Luke Lluis M Mir Willem W Overwijk Michael Postow Igor Puzanov Paul Sondel Janis M Taube Per Thor Straten David F Stroncek Jennifer A Wargo Hassane Zarour Magdalena Thurin

J Transl Med 2017 11 16;15(1):236. Epub 2017 Nov 16.

Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, NCI, NIH, Rockville, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691855PMC
November 2017

High Antigen Processing Machinery component expression in Langerhans cells from melanoma patients' sentinel lymph nodes.

Authors:
Maria Raffaella Romoli Paola Di Gennaro Gianni Gerlini Serena Sestini Paola Brandani Soldano Ferrone Lorenzo Borgognoni

Cell Immunol 2017 Oct 30;320:29-37. Epub 2017 Aug 30.

Plastic and Reconstructive Surgery Unit, Regional Melanoma Referral Center and Melanoma & Skin Cancer Unit, Tuscan Tumour Institute (ITT) - S.M. Annunziata Hospital, Florence, Italy.

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October 2017

ADAM12-L confers acquired 5-fluorouracil resistance in breast cancer cells.

Authors:
Xuedong Wang Yueping Wang Juan Gu Daoping Zhou Zhimin He Xinhui Wang Soldano Ferrone

Sci Rep 2017 08 29;7(1):9687. Epub 2017 Aug 29.

Department of Medical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575004PMC
August 2017

Expression status of folate receptor alpha is a predictor of survival in pancreatic ductal adenocarcinoma.

Authors:
Lei Cai Theodoros Michelakos Cristina R Ferrone Liyuan Zhang Vikram Deshpande Qi Shen Albert DeLeo Teppei Yamada Gong Zhang Soldano Ferrone Xinhui Wang

Oncotarget 2017 Jun;8(23):37646-37656

Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514937PMC
June 2017

Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma.

Authors:
Cathrin Ritter Kaiji Fan Annette Paschen Sine Reker Hardrup Soldano Ferrone Paul Nghiem Selma Ugurel David Schrama Jürgen C Becker

Sci Rep 2017 05 23;7(1):2290. Epub 2017 May 23.

Department of Translational Skin Cancer Research, University Hospital Essen, Essen, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442125PMC
May 2017

Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy.

Authors:
Katherine S Yang Hyungsoon Im Seonki Hong Ilaria Pergolini Andres Fernandez Del Castillo Rui Wang Susan Clardy Chen-Han Huang Craig Pille Soldano Ferrone Robert Yang Cesar M Castro Hakho Lee Carlos Fernandez Del Castillo Ralph Weissleder

Sci Transl Med 2017 05;9(391)

Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846089PMC
May 2017

B7-H3-targeted Pb radioimmunotherapy of ovarian cancer in preclinical models.

Authors:
Benjamin B Kasten Rebecca C Arend Ashwini A Katre Harrison Kim Jinda Fan Soldano Ferrone Kurt R Zinn Donald J Buchsbaum

Nucl Med Biol 2017 Apr 10;47:23-30. Epub 2017 Jan 10.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340614PMC
April 2017

Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy.

Authors:
Cristina Maccalli Giorgio Parmiani Soldano Ferrone

Immunol Invest 2017 Apr 13;46(3):221-238. Epub 2017 Mar 13.

c Department of Surgery , Massachusetts General Hospital, Harvard Medical School , Boston , MA , USA.

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April 2017

FCγ Chimeric Receptor-Engineered T Cells: Methodology, Advantages, Limitations, and Clinical Relevance.

Authors:
Sara Caratelli Tommaso Sconocchia Roberto Arriga Andrea Coppola Giulia Lanzilli Davide Lauro Adriano Venditti Maria Ilaria Del Principe Francesco Buccisano Luca Maurillo Soldano Ferrone Giuseppe Sconocchia

Front Immunol 2017 27;8:457. Epub 2017 Apr 27.

Institute of Translational Pharmacology, CNR, Rome, Italy.

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http://dx.doi.org/10.3389/fimmu.2017.00457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406408PMC
April 2017

Chondroitin sulfate proteoglycan-4 (CSPG4)-specific monoclonal antibody 225.28 in detection of acute myeloid leukemia blasts.

Authors:
Moon Fenton Theresa L Whiteside Soldano Ferrone Michael Boyiadzis

Oncol Res 2015 ;22(2):117-21

Division of Hematology and Oncology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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February 2017

CD137 Stimulation Enhances Cetuximab-Induced Natural Killer: Dendritic Cell Priming of Antitumor T-Cell Immunity in Patients with Head and Neck Cancer.

Authors:
Raghvendra M Srivastava Sumita Trivedi Fernando Concha-Benavente Sandra P Gibson Carly Reeder Soldano Ferrone Robert L Ferris

Clin Cancer Res 2017 Feb 5;23(3):707-716. Epub 2016 Aug 5.

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290200PMC
February 2017

HLA class II antigen-processing pathway in tumors: Molecular defects and clinical relevance.

Authors:
Barbara Seliger Matthias Kloor Soldano Ferrone

Oncoimmunology 2017 6;6(2):e1171447. Epub 2017 Feb 6.

Departments of Surgery and Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School , Boston, MA, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1171447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353941PMC
February 2017

Phosphorylated Histone H3 (PHH3) Is a Superior Proliferation Marker for Prognosis of Pancreatic Neuroendocrine Tumors.

Authors:
Vincenzo Villani Krishnan K Mahadevan Matteo Ligorio Carlos Fernández-Del Castillo David T Ting Francesco Sabbatino Irene Zhang Mark Vangel Soldano Ferrone Andrew L Warshaw Keith D Lillemoe Jennifer Wargo Vikram Deshpande Cristina R Ferrone

Ann Surg Oncol 2016 12 28;23(Suppl 5):609-617. Epub 2016 Mar 28.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1245/s10434-016-5171-xDOI Listing
December 2016

Anti-EGFR Targeted Monoclonal Antibody Isotype Influences Antitumor Cellular Immunity in Head and Neck Cancer Patients.

Authors:
Sumita Trivedi Raghvendra M Srivastava Fernando Concha-Benavente Soldano Ferrone Tatiana M Garcia-Bates Jing Li Robert L Ferris

Clin Cancer Res 2016 Nov 23;22(21):5229-5237. Epub 2016 May 23.

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093040PMC
November 2016

Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.

Authors:
Paolo A Ascierto Sanjiv Agarwala Gerardo Botti Alessandra Cesano Gennaro Ciliberto Michael A Davies Sandra Demaria Reinhard Dummer Alexander M Eggermont Soldano Ferrone Yang Xin Fu Thomas F Gajewski Claus Garbe Veronica Huber Samir Khleif Michael Krauthammer Roger S Lo Giuseppe Masucci Giuseppe Palmieri Michael Postow Igor Puzanov Ann Silk Stefani Spranger David F Stroncek Ahmad Tarhini Janis M Taube Alessandro Testori Ena Wang Jennifer A Wargo Cassian Yee Hassane Zarour Laurence Zitvogel Bernard A Fox Nicola Mozzillo Francesco M Marincola Magdalena Thurin

J Transl Med 2016 11 15;14(1):313. Epub 2016 Nov 15.

Cancer Diagnosis Program, National Cancer Institute, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1186/s12967-016-1070-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111349PMC
November 2016

AIRE polymorphism, melanoma antigen-specific T cell immunity, and susceptibility to melanoma.

Authors:
Giuseppina Conteduca Daniela Fenoglio Alessia Parodi Florinda Battaglia Francesca Kalli Simone Negrini Samuele Tardito Francesca Ferrera Annalisa Salis Enrico Millo Giuseppe Pasquale Giusi Barra Gianluca Damonte Francesco Indiveri Soldano Ferrone Gilberto Filaci

Oncotarget 2016 Sep;7(38):60872-60884

Centre of Excellence for Biomedical Research, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.18632/oncotarget.11506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308622PMC
September 2016

Antitumor Activity of BRAF Inhibitor and IFNα Combination in BRAF-Mutant Melanoma.

Authors:
Francesco Sabbatino Yangyang Wang Giosuè Scognamiglio Elvira Favoino Steven A Feldman Vincenzo Villani Keith T Flaherty Sjoerd Nota Diana Giannarelli Ester Simeone Anna M Anniciello Giuseppe Palmieri Stefano Pepe Gerardo Botti Paolo A Ascierto Cristina R Ferrone Soldano Ferrone

J Natl Cancer Inst 2016 Jul 5;108(7). Epub 2016 Feb 5.

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http://dx.doi.org/10.1093/jnci/djv435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948304PMC
July 2016

Immunological and clinical significance of HLA class I antigen processing machinery component defects in malignant cells.

Authors:
Fernando Concha-Benavente Raghvendra Srivastava Soldano Ferrone Robert L Ferris

Oral Oncol 2016 07 2;58:52-8. Epub 2016 Jun 2.

Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA, USA; Cancer Immunology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2016.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264518PMC
July 2016

CSPG4 as a prognostic biomarker in chordoma.

Authors:
Andrew J Schoenfeld Xinhui Wang Yangyang Wang Francis J Hornicek G Petur Nielsen Zhenfeng Duan Soldano Ferrone Joseph H Schwab

Spine J 2016 06 9;16(6):722-7. Epub 2015 Dec 9.

Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.spinee.2015.11.059DOI Listing
June 2016

Chondroitin sulfate proteoglycan 4 as a target for chimeric antigen receptor-based T-cell immunotherapy of solid tumors.

Authors:
Yangyang Wang Claudia Geldres Soldano Ferrone Gianpietro Dotti

Expert Opin Ther Targets 2015 18;19(10):1339-50. Epub 2015 Jul 18.

c 3 University of North Carolina, Lineberger Comprehensive Cancer Center , Chapel Hill, NC, USA

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May 2016

HLA class I downregulation is associated with enhanced NK-cell killing of melanoma cells with acquired drug resistance to BRAF inhibitors.

Authors:
Rosa Sottile Pradeepa N Pangigadde Thomas Tan Andrea Anichini Francesco Sabbatino Francesca Trecroci Elvira Favoino Laura Orgiano James Roberts Soldano Ferrone Klas Kärre Francesco Colucci Ennio Carbone

Eur J Immunol 2016 Feb 20;46(2):409-19. Epub 2015 Dec 20.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1002/eji.201445289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832274PMC
February 2016

Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells.

Authors:
Sofia R Gameiro Anthony S Malamas Kwong Y Tsang Soldano Ferrone James W Hodge

Oncotarget 2016 Feb;7(7):7390-402

Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.18632/oncotarget.7180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884926PMC
February 2016

PD-L1 and HLA Class I Antigen Expression and Clinical Course of the Disease in Intrahepatic Cholangiocarcinoma.

Authors:
Francesco Sabbatino Vincenzo Villani Jennifer H Yearley Vikram Deshpande Lei Cai Ioannis T Konstantinidis Christina Moon Sjoerd Nota Yangyang Wang Ahmad Al-Sukaini Andrew X Zhu Lipika Goyal David T Ting Nabeel Bardeesy Theodore S Hong Carlos Fernandez-del Castillo Kenneth K Tanabe Keith D Lillemoe Soldano Ferrone Cristina R Ferrone

Clin Cancer Res 2016 Jan 15;22(2):470-8. Epub 2015 Sep 15.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296951PMC
January 2016

Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage.

Authors:
Roberto Arriga Sara Caratelli Andrea Coppola Giulio Cesare Spagnoli Adriano Venditti Sergio Amadori Giulia Lanzilli Davide Lauro Patrizia Palomba Tommaso Sconocchia Maria Ilaria Del Principe Luca Maurillo Francesco Buccisano Barbara Capuani Soldano Ferrone Giuseppe Sconocchia

Oncotarget 2016 Jan;7(2):2070-9

Laboratory of Tumor Immunology and Immunotherapy, Institute of Translational Pharmacology, Department of Biomedicine, National Research Council (CNR), Rome, Italy.

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http://dx.doi.org/10.18632/oncotarget.6529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811516PMC
January 2016

Intracellular antigens as targets for antibody based immunotherapy of malignant diseases.

Authors:
Yangyang Wang Xinhui Wang Cristina R Ferrone Joseph H Schwab Soldano Ferrone

Mol Oncol 2015 Dec 30;9(10):1982-93. Epub 2015 Oct 30.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, United States; Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, United States. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528737PMC
December 2015

Future perspectives in melanoma research: meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014.

Authors:
Paolo A Ascierto Michael Atkins Carlo Bifulco Gerardo Botti Alistair Cochran Michael Davies Sandra Demaria Reinhard Dummer Soldano Ferrone Silvia Formenti Thomas F Gajewski Claus Garbe Samir Khleif Rolf Kiessling Roger Lo Paul Lorigan Grant Mc Arthur Giuseppe Masucci Ignacio Melero Martin Mihm Giuseppe Palmieri Giorgio Parmiani Igor Puzanov Pedro Romero Bastian Schilling Barbara Seliger David Stroncek Janis Taube Sara Tomei Hassane M Zarour Alessandro Testori Ena Wang Jérôme Galon Gennaro Ciliberto Nicola Mozzillo Francesco M Marincola Magdalena Thurin

J Transl Med 2015 Nov 30;13:374. Epub 2015 Nov 30.

Cancer Diagnosis Program, National Cancer Institute, NIH, Bethesda, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665874PMC
November 2015

Multiple structural and epigenetic defects in the human leukocyte antigen class I antigen presentation pathway in a recurrent metastatic melanoma following immunotherapy.

Authors:
Chien-Chung Chang Giuseppe Pirozzi Shao-Hsuan Wen I-Hsin Chung Bau-Lin Chiu Simona Errico Monica Luongo Maria Luisa Lombardi Soldano Ferrone

J Biol Chem 2015 Oct 17;290(44):26562-75. Epub 2015 Sep 17.

Departments of Surgery and of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114.

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http://dx.doi.org/10.1074/jbc.M115.676130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646314PMC
October 2015

STAT1-Induced HLA Class I Upregulation Enhances Immunogenicity and Clinical Response to Anti-EGFR mAb Cetuximab Therapy in HNC Patients.

Authors:
Raghvendra M Srivastava Sumita Trivedi Fernando Concha-Benavente Jie Hyun-Bae Lin Wang Raja R Seethala Barton F Branstetter Soldano Ferrone Robert L Ferris

Cancer Immunol Res 2015 Aug 13;3(8):936-45. Epub 2015 May 13.

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania. Cancer Immunology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526378PMC
August 2015

Anti-proliferative and pro-apoptotic activity of GD2 ganglioside-specific monoclonal antibody 3F8 in human melanoma cells.

Authors:
Chun-Yen Tsao Francesco Sabbatino Nai-Kong V Cheung Jeff Chi-Feng Hsu Vincenzo Villani Xinhui Wang Soldano Ferrone

Oncoimmunology 2015 08 2;4(8):e1023975. Epub 2015 Apr 2.

Department of Surgery; Massachusetts General Hospital; Harvard Medical School ; Boston, MA USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570105PMC
August 2015

CTLA-4⁺ Regulatory T Cells Increased in Cetuximab-Treated Head and Neck Cancer Patients Suppress NK Cell Cytotoxicity and Correlate with Poor Prognosis.

Authors:
Hyun-Bae Jie Patrick J Schuler Steve C Lee Raghvendra M Srivastava Athanassios Argiris Soldano Ferrone Theresa L Whiteside Robert L Ferris

Cancer Res 2015 Jun 1;75(11):2200-10. Epub 2015 Apr 1.

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania. Cancer Immunology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-2788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452385PMC
June 2015

Melanoma initiating cells: where do we stand?

Authors:
Vincenzo Villani Francesco Sabbatino Cristina R Ferrone Soldano Ferrone

Melanoma Manag 2015 May 18;2(2):109-114. Epub 2015 May 18.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.2217/mmt.15.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094641PMC
May 2015

Association of high CD4-positive T cell infiltration with mutations in HLA class II-regulatory genes in microsatellite-unstable colorectal cancer.

Authors:
Eva-Maria Surmann Anita Y Voigt Sara Michel Kathrin Bauer Miriam Reuschenbach Soldano Ferrone Magnus von Knebel Doeberitz Matthias Kloor

Cancer Immunol Immunother 2015 Mar 2;64(3):357-66. Epub 2014 Dec 2.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00262-014-1638-4DOI Listing
March 2015

Limited genomic heterogeneity of circulating melanoma cells in advanced stage patients.

Authors:
Carmen Ruiz Julia Li Madelyn S Luttgen Anand Kolatkar Jude T Kendall Edna Flores Zheng Topp Wolfram E Samlowski Edward McClay Kelly Bethel Soldano Ferrone James Hicks Peter Kuhn

Phys Biol 2015 Jan 9;12(1):016008. Epub 2015 Jan 9.

Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1088/1478-3975/12/1/016008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023009PMC
January 2015

Genetic evolution of T-cell resistance in the course of melanoma progression.

Authors:
Antje Sucker Fang Zhao Birgit Real Christina Heeke Nicola Bielefeld Stefan Maβen Susanne Horn Iris Moll Raffaela Maltaner Peter A Horn Bastian Schilling Francesco Sabbatino Volker Lennerz Matthias Kloor Soldano Ferrone Dirk Schadendorf Christine S Falk Klaus Griewank Annette Paschen

Clin Cancer Res 2014 Dec 7;20(24):6593-604. Epub 2014 Oct 7.

Department of Dermatology, University Hospital Essen, University Duisburg-Essen, Essen, Germany. German Cancer Consortium (DKTK), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0567DOI Listing
December 2014

Enrichment of CD56(dim)KIR + CD57 + highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients.

Authors:
Talib Hassan Ali Simona Pisanti Elena Ciaglia Roberta Mortarini Andrea Anichini Cinzia Garofalo Rossana Tallerico Mario Santinami Elio Gulletta Caterina Ietto Mario Galgani Giuseppe Matarese Maurizio Bifulco Soldano Ferrone Francesco Colucci Alessandro Moretta Klas Kärre Ennio Carbone

Nat Commun 2014 Dec 4;5:5639. Epub 2014 Dec 4.

Department of Experimental and Clinical Medicine "G. Salvatore", University of Catanzaro 'Magna Graecia', Catanzaro, 88100, Italy.

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http://dx.doi.org/10.1038/ncomms6639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338526PMC
December 2014

Effect of p53 activity on the sensitivity of human glioblastoma cells to PARP-1 inhibitor in combination with topoisomerase I inhibitor or radiation.

Authors:
Francesco Sabbatino Celeste Fusciello Domenico Somma Roberto Pacelli Ravin Poudel David Pepin Antonio Leonardi Chiara Carlomagno Giuseppina Della Vittoria Scarpati Soldano Ferrone Stefano Pepe

Cytometry A 2014 Nov 2;85(11):953-61. Epub 2014 Sep 2.

Department of Clinical Medicine and Surgery, University of Naples "Federico II", Via Sergio Pansini 5, Naples, Italy, 80131; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, 02114.

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http://dx.doi.org/10.1002/cyto.a.22563DOI Listing
November 2014

Future perspectives in melanoma research: meeting report from the "Melanoma Bridge", Napoli, December 5th-8th 2013.

Authors:
Paolo A Ascierto Antonio M Grimaldi Ana Carrizosa Anderson Carlo Bifulco Alistair Cochran Claus Garbe Alexander M Eggermont Mark Faries Soldano Ferrone Jeffrey E Gershenwald Thomas F Gajewski Ruth Halaban F Stephen Hodi Richard Kefford John M Kirkwood James Larkin Sancy Leachman Michele Maio Richard Marais Giuseppe Masucci Ignacio Melero Giuseppe Palmieri Igor Puzanov Antoni Ribas Yvonne Saenger Bastian Schilling Barbara Seliger David Stroncek Ryan Sullivan Alessandro Testori Ena Wang Gennaro Ciliberto Nicola Mozzillo Francesco M Marincola Magdalena Thurin

J Transl Med 2014 Oct 28;12:277. Epub 2014 Oct 28.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232645PMC
October 2014

Therapeutic monoclonal antibodies: introduction.

Authors:
Soldano Ferrone

Semin Oncol 2014 Oct 28;41(5):556-8. Epub 2014 Sep 28.

Massachusetts General Hospital, Boston, MA. Electronic address:

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October 2014

Novel tumor antigen-specific monoclonal antibody-based immunotherapy to eradicate both differentiated cancer cells and cancer-initiating cells in solid tumors.

Authors:
Francesco Sabbatino Yangyang Wang Xinhui Wang Joseph H Schwab Soldano Ferrone Cristina R Ferrone

Semin Oncol 2014 Oct 12;41(5):685-99. Epub 2014 Aug 12.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1053/j.seminoncol.2014.08.007DOI Listing
October 2014

Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells.

Authors:
Rachel E Beard Zhili Zheng Kiran H Lagisetty William R Burns Eric Tran Stephen M Hewitt Daniel Abate-Daga Shannon F Rosati Howard A Fine Soldano Ferrone Steven A Rosenberg Richard A Morgan

J Immunother Cancer 2014 19;2:25. Epub 2014 Aug 19.

Surgery Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, Building 10 Hatfield CRC, Rm 3-5930, 20892-1201 Bethesda, MD, USA ; Current address: Bluebird bio, 150 Second St, Cambridge, MA 02141, USA.

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http://dx.doi.org/10.1186/2051-1426-2-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155770PMC
September 2014

Dendritic cell maturation in HCV infection: altered regulation of MHC class I antigen processing-presenting machinery.

Authors:
Patrizia Leone Mariangela Di Tacchio Simona Berardi Teresa Santantonio Massimo Fasano Soldano Ferrone Angelo Vacca Franco Dammacco Vito Racanelli

J Hepatol 2014 Aug 13;61(2):242-51. Epub 2014 Apr 13.

Department of Internal Medicine and Clinical Oncology, University of Bari Medical School, Bari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.04.007DOI Listing
August 2014

NK cells and T cells cooperate during the clinical course of colorectal cancer.

Authors:
Giuseppe Sconocchia Serenella Eppenberger Giulio C Spagnoli Luigi Tornillo Raoul Droeser Sara Caratelli Francesca Ferrelli Andrea Coppola Roberto Arriga Davide Lauro Giandomenica Iezzi Luigi Terracciano Soldano Ferrone

Oncoimmunology 2014;3(8):e952197. Epub 2014 Aug 3.

Department of Surgery; Massachusetts General Hospital; Harvard Medical School ; Boston, MA USA.

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http://dx.doi.org/10.4161/21624011.2014.952197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292408PMC
August 2014

Programmed cell death ligand 1 expression in osteosarcoma.

Authors:
Jacson K Shen Gregory M Cote Edwin Choy Pei Yang David Harmon Joseph Schwab G Petur Nielsen Ivan Chebib Soldano Ferrone Xinhui Wang Yangyang Wang Henry Mankin Francis J Hornicek Zhenfeng Duan

Cancer Immunol Res 2014 Jul 21;2(7):690-698. Epub 2014 Apr 21.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, United States.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082476PMC
July 2014

CSPG4-specific immunity and survival prolongation in dogs with oral malignant melanoma immunized with human CSPG4 DNA.

Authors:
Federica Riccardo Selina Iussich Lorella Maniscalco Saray Lorda Mayayo Giuseppe La Rosa Maddalena Arigoni Raffaella De Maria Francesca Gattino Stefania Lanzardo Elena Lardone Marina Martano Emanuela Morello Simone Prestigio Alessandra Fiore Elena Quaglino Sara Zabarino Soldano Ferrone Paolo Buracco Federica Cavallo

Clin Cancer Res 2014 Jul 29;20(14):3753-62. Epub 2014 May 29.

Authors' Affiliations: Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino;

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3042DOI Listing
July 2014

Detection of chondroitin sulfate proteoglycan 4 (CSPG4) in melanoma.

Authors:
Yangyang Wang Francesco Sabbatino Xinhui Wang Soldano Ferrone

Methods Mol Biol 2014 ;1102:523-35

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-62703-727-3_28DOI Listing
June 2014

Ipilimumab in the treatment of metastatic melanoma: management of adverse events.

Authors:
Giuseppina Della Vittoria Scarpati Celeste Fusciello Francesco Perri Francesco Sabbatino Soldano Ferrone Chiara Carlomagno Stefano Pepe

Onco Targets Ther 2014 19;7:203-9. Epub 2014 Feb 19.

Department of Medicine, University of Salerno, Salerno, Italy ; Division of Oncology, "San Giovanni di Dio e Ruggi d'Aragona" Hospital, Salerno, Italy.

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http://dx.doi.org/10.2147/OTT.S57335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933725PMC
June 2014

Blocking the formation of radiation-induced breast cancer stem cells.

Authors:
Yangyang Wang Wende Li Shalin S Patel Juan Cong Nan Zhang Francesco Sabbatino Xiaoyan Liu Yuan Qi Peigen Huang Hang Lee Alphonse Taghian Jian-Jian Li Albert B DeLeo Soldano Ferrone Michael W Epperly Cristina R Ferrone Amy Ly Elena F Brachtel Xinhui Wang

Oncotarget 2014 Jun;5(11):3743-55

Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116517PMC
http://dx.doi.org/10.18632/oncotarget.1992DOI Listing
June 2014

PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.

Authors:
Francesco Sabbatino Yangyang Wang Xinhui Wang Keith T Flaherty Ling Yu David Pepin Giosue Scognamiglio Stefano Pepe John M Kirkwood Zachary A Cooper Dennie T Frederick Jennifer A Wargo Soldano Ferrone Cristina R Ferrone

Oncotarget 2014 Apr;5(7):1926-41

Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039118PMC
http://dx.doi.org/10.18632/oncotarget.1878DOI Listing
April 2014

IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.

Authors:
Fabio Morandi Emma Di Carlo Soldano Ferrone Andrea Petretto Vito Pistoia Irma Airoldi

J Immunol 2014 Mar 19;192(6):2634-42. Epub 2014 Feb 19.

Laboratorio di Oncologia, Istituto Giannina Gaslini, 16147 Genoa, Italy;

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http://dx.doi.org/10.4049/jimmunol.1302656DOI Listing
March 2014

T lymphocytes redirected against the chondroitin sulfate proteoglycan-4 control the growth of multiple solid tumors both in vitro and in vivo.

Authors:
Claudia Geldres Barbara Savoldo Valentina Hoyos Ignazio Caruana Ming Zhang Eric Yvon Michele Del Vecchio Chad J Creighton Michael Ittmann Soldano Ferrone Gianpietro Dotti

Clin Cancer Res 2014 Feb 13;20(4):962-71. Epub 2013 Dec 13.

Authors' Affiliations: Center for Cell and Gene Therapy; Departments of Pediatrics, Pathology and Immunology, and Medicine, Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine; Houston Methodist Hospital and Texas Children's Hospital; Department of Surgery, Michael E. DeBakey Department of Veterans Affairs Medical Center; Dan L. Duncan Cancer Center Division of Biostatistics, Baylor College of Medicine, Houston, Texas; and Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944408PMC
February 2014

Monoclonal antibody-based immunotherapy of ovarian cancer: targeting ovarian cancer cells with the B7-H3-specific mAb 376.96.

Authors:
Janelle M Fauci Francesco Sabbatino Yangyang Wang Angelina I Londoño-Joshi J Michael Straughn Charles N Landen Soldano Ferrone Donald J Buchsbaum

Gynecol Oncol 2014 Jan 9;132(1):203-10. Epub 2013 Nov 9.

University of Alabama at Birmingham, Department of Radiation Oncology, USA.

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http://dx.doi.org/10.1016/j.ygyno.2013.10.038DOI Listing
January 2014

Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4.

Authors:
Andrea Volonté Tiziano Di Tomaso Michela Spinelli Matilde Todaro Francesca Sanvito Luca Albarello Massimiliano Bissolati Luca Ghirardelli Elena Orsenigo Soldano Ferrone Claudio Doglioni Giorgio Stassi Paolo Dellabona Carlo Staudacher Giorgio Parmiani Cristina Maccalli

J Immunol 2014 Jan 25;192(1):523-32. Epub 2013 Nov 25.

Unit of Immuno-Biotherapy of Melanoma and Solid Tumors, San Raffaele Foundation Centre, 20132 Milan, Italy;

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http://www.jimmunol.org/content/early/2013/11/25/jimmunol.13
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1301342
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http://dx.doi.org/10.4049/jimmunol.1301342DOI Listing
January 2014

Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing.

Authors:
Sofia R Gameiro Momodou L Jammeh Max M Wattenberg Kwong Y Tsang Soldano Ferrone James W Hodge

Oncotarget 2014 Jan;5(2):403-16

Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964216PMC
http://dx.doi.org/10.18632/oncotarget.1719DOI Listing
January 2014

HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker.

Authors:
Giuseppe Sconocchia Serenella Eppenberger-Castori Inti Zlobec Eva Karamitopoulou Roberto Arriga Andrea Coppola Sara Caratelli Giulio Cesare Spagnoli Davide Lauro Alessandro Lugli Junyi Han Giandomenica Iezzi Cristina Ferrone Amedeo Ferlosio Luigi Tornillo Raoul Droeser Piero Rossi Antonio Attanasio Soldano Ferrone Luigi Terracciano

Neoplasia 2014 Jan;16(1):31-42

Institute of Pathology, University of Basel, Basel, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924546PMC
http://dx.doi.org/10.1593/neo.131568DOI Listing
January 2014

Emerging BRAF inhibitors for melanoma.

Authors:
Francesco Sabbatino Yangyang Wang Xinhui Wang Soldano Ferrone Cristina R Ferrone

Expert Opin Emerg Drugs 2013 Dec 27;18(4):431-43. Epub 2013 Sep 27.

Massachusetts General Hospital, Harvard Medical School, Department of Surgery , 55 Fruit Street, Boston, MA 02114 , USA +1 617 726 6087 ;

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http://dx.doi.org/10.1517/14728214.2013.842975DOI Listing
December 2013

EGFR-mediated tumor immunoescape: The imbalance between phosphorylated STAT1 and phosphorylated STAT3.

Authors:
Fernando Concha-Benavente Raghvendra M Srivastava Soldano Ferrone Robert L Ferris

Oncoimmunology 2013 Dec 5;2(12):e27215. Epub 2013 Dec 5.

Department of Immunology; University of Pittsburgh; Pittsburgh, PA USA ; Department of Otolaryngology; University of Pittsburgh; Pittsburgh, PA USA ; Cancer Immunology Program; University of Pittsburgh Cancer Institute; Pittsburgh, PA USA.

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http://www.tandfonline.com/doi/abs/10.4161/onci.27215
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http://dx.doi.org/10.4161/onci.27215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913673PMC
December 2013

Characterization of human afferent lymph dendritic cells from seroma fluids.

Authors:
Barbara Morandi Irene Bonaccorsi Mario Mesiti Romana Conte Paolo Carrega Gregorio Costa Raffaella Iemmo Stefania Martini Soldano Ferrone Claudia Cantoni Maria Cristina Mingari Lorenzo Moretta Guido Ferlazzo

J Immunol 2013 Nov 27;191(9):4858-66. Epub 2013 Sep 27.

Department of Experimental Medicine, University of Genoa, 16132 Genoa, Italy;

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http://dx.doi.org/10.4049/jimmunol.1300760DOI Listing
November 2013

Pathologic and gene expression features of metastatic melanomas to the brain.

Authors:
Ronald Hamilton Michal Krauze Marjorie Romkes Bernard Omolo Panagiotis Konstantinopoulos Todd Reinhart Malgorzata Harasymczuk YangYang Wang Yan Lin Soldano Ferrone Theresa Whiteside Stephanie Bortoluzzi Jonette Werley Tomoko Nukui Beth Fallert-Junecko Douglas Kondziolka Joseph Ibrahim Dorothea Becker John Kirkwood Stergios Moschos

Cancer 2013 Aug 21;119(15):2737-46. Epub 2013 May 21.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1002/cncr.28029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901051PMC
August 2013

Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".

Authors:
Paolo A Ascierto Antonio M Grimaldi Nicolas Acquavella Lorenzo Borgognoni Luana Calabrò Natale Cascinelli Alessandra Cesano Michele Del Vecchio Alexander M Eggermont Mark Faries Soldano Ferrone Bernard A Fox Thomas F Gajewski Jérôme Galon Sacha Gnjatic Helen Gogas Mohammed Kashani-Sabet Howard L Kaufman James Larkin Roger S Lo Alberto Mantovani Kim Margolin Cornelis Melief Grant McArthur Giuseppe Palmieri Igor Puzanov Antoni Ribas Barbara Seliger Jeff Sosman Peter Suenaert Ahmad A Tarhini Giorgio Trinchieri Fernando Vidal-Vanaclocha Ena Wang Gennaro Ciliberto Nicola Mozzillo Francesco M Marincola Magdalena Thurin

J Transl Med 2013 Jun 3;11:137. Epub 2013 Jun 3.

Istituto Nazionale Tumori, Fondazione "G, Pascale", Naples, Italy.

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http://dx.doi.org/10.1186/1479-5876-11-137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681569PMC
June 2013