Publications by authors named "Sofianos Andrikopoulos"

76Publications

Glycaemia and utilisation of technology across the lifespan of adults with type 1 diabetes: Results of the Australian National Diabetes Audit (ANDA).

Diabetes Res Clin Pract 2020 Dec 10;171:108609. Epub 2020 Dec 10.

School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Monash Health, Melbourne, Victoria, Australia; Alfred Health, Melbourne, Victoria, Australia. Electronic address:

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December 2020

E2f8 and Dlg2 genes have independent effects on impaired insulin secretion associated with hyperglycaemia.

Diabetologia 2020 07 30;63(7):1333-1348. Epub 2020 Apr 30.

Department of Medicine (Austin Health), Austin Hospital, University of Melbourne, Level 7, Lance Townsend Building, Studley Road, Heidelberg, VIC, 3084, Australia.

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July 2020

Impaired exercise performance is independent of inflammation and cellular stress following genetic reduction or deletion of selenoprotein S.

Am J Physiol Regul Integr Comp Physiol 2020 05 18;318(5):R981-R996. Epub 2020 Mar 18.

Centre for Molecular and Medical Research, School of Medicine, Deakin University, Geelong, Victoria, Australia.

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May 2020

Breathing life into Australian diabetes clinical guidelines.

Med J Aust 2020 04 14;212(6):250-251.e1. Epub 2020 Feb 14.

Monash University, Melbourne, VIC.

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April 2020

Risk-adjustment of diabetes health outcomes improves the accuracy of performance benchmarking.

Sci Rep 2018 07 6;8(1):10261. Epub 2018 Jul 6.

Monash University, Diabetes, Vascular Health and Ageing, Division of Metabolism, Ageing and Genomics, School of Public Health and Preventive Medicine, Melbourne, 3004, Australia.

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July 2018

Probing the correlation between insulin activity and structural stability through introduction of the rigid A6-A11 bond.

J Biol Chem 2018 07 13;293(30):11928-11943. Epub 2018 Jun 13.

From the College of Medicine and Public Health, Flinders University of South Australia, Bedford Park, South Australia 5042, Australia,

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July 2018

Burden of cardiovascular risk factors and disease among patients with type 1 diabetes: results of the Australian National Diabetes Audit (ANDA).

Cardiovasc Diabetol 2018 06 2;17(1):77. Epub 2018 Jun 2.

School of Public Health and Preventive Medicine, Monash University, 5th Floor, The Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.

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June 2018

Deficiency of selenoprotein S, an endoplasmic reticulum resident oxidoreductase, impairs the contractile function of fast-twitch hindlimb muscles.

Am J Physiol Regul Integr Comp Physiol 2018 08 18;315(2):R380-R396. Epub 2018 Apr 18.

Centre for Molecular and Medical Research, School of Medicine, Deakin University, Waurn Ponds, Victoria , Australia.

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August 2018

The androgen receptor in bone marrow progenitor cells negatively regulates fat mass.

J Endocrinol 2018 04 31;237(1):15-27. Epub 2018 Jan 31.

Department of MedicineAustin Health, University of Melbourne, Heidelberg, Victoria, Australia

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April 2018

Diabetic ketoacidosis in acromegaly; a rare complication precipitated by corticosteroid use.

Diabetes Res Clin Pract 2017 Dec 19;134:29-37. Epub 2017 Sep 19.

Department of Endocrinology, Austin Health, Level 2 Centaur Building, Repatriation Campus Heidelberg West, Victoria 3084, Australia; Department of Medicine, Austin Health and the University of Melbourne (Austin Campus), Parkville, VIC 3010, Australia. Electronic address:

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December 2017

Dapagliflozin improves insulin resistance and glucose intolerance in a novel transgenic rat model of chronic glucose overproduction and glucose toxicity.

Diabetes Obes Metab 2017 08 6;19(8):1135-1146. Epub 2017 Apr 6.

Department of Medicine, Austin Hospital, University of Melbourne, Heidelberg, Victoria, Australia.

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August 2017

High fat feeding unmasks variable insulin responses in male C57BL/6 mouse substrains.

J Endocrinol 2017 04 30;233(1):53-64. Epub 2017 Jan 30.

Veterans Affairs Puget Sound Health Care SystemSeattle, Washington, USA

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April 2017

Narrow-leafed lupin (Lupinus angustifolius L.) β-conglutin proteins modulate the insulin signaling pathway as potential type 2 diabetes treatment and inflammatory-related disease amelioration.

Mol Nutr Food Res 2017 05 13;61(5). Epub 2017 Feb 13.

Plant Reproductive Biology Laboratory; Deptartment of Biochemistry, Cell & Molecular Biology of Plants, Estacion Experimental del Zaidin, Spanish National Research Council (CSIC), Granada, Spain.

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May 2017

Erratum to: Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice.

Diabetologia 2016 12;59(12):2729

Metabolic Disease and Obesity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC, 3800, Australia.

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December 2016

Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice.

Diabetologia 2016 12 15;59(12):2632-2644. Epub 2016 Sep 15.

Metabolic Disease and Obesity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC, 3800, Australia.

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December 2016

The Paleo diet and diabetes.

Med J Aust 2016 Aug;205(4):151-2

University of Melbourne, Melbourne, VIC

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August 2016

Chewing the fat for better insulin secretion.

Mol Metab 2016 Jan 21;5(1):3-4. Epub 2015 Oct 21.

University of Melbourne, Department of Medicine (AH), Austin Health, Heidelberg Victoria 3084, Australia.

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January 2016

Identification of ABCC8 as a contributory gene to impaired early-phase insulin secretion in NZO mice.

J Endocrinol 2016 Jan 22;228(1):61-73. Epub 2015 Oct 22.

Department of Medicine (AH)Austin Hospital, University of Melbourne, Level 7, Lance Townsend Building, Studley Road, Heidelberg, Victoria 3084, AustraliaWalter and Eliza Hall Institute of Medical ResearchParkville, 3010 Victoria, AustraliaHarry Perkins Institute of Medical ResearchNedlands, Western Australia 6009, AustraliaThe School of Medical Sciences Edith Cowan UniversityJoondalup Western Australia 6027, Australia.

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January 2016

Contribution of the hypothalamus and gut to weight gain susceptibility and resistance in mice.

J Endocrinol 2015 Jun 1;225(3):191-204. Epub 2015 May 1.

Department of Medicine (Austin Health) Austin Hospital, The University of Melbourne, Level 7, Lance Townsend Building, Studley Road, Heidelberg, Victoria 3084, Australia

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June 2015

Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly.

FASEB J 2015 Apr 30;29(4):1426-34. Epub 2014 Dec 30.

*Surgical Oncology Research Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; University of Melbourne Department of Medicine, Austin Health, Heidelberg, Victoria, Australia; Translational Research Laboratories, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; St. Vincent's Institute of Medical Research and University of Melbourne Department of Medicine, St. Vincent's Hospital, Fitzroy, Victoria, Australia; Bone Research Program, ANZAC Research Institute, The University of Sydney, Sydney, New South Wales, Australia; Differentiation and Transcription Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; **Department of Pathology, University of Melbourne, Parkville, Victoria, Australia; Molecular Oncology Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; and University of Melbourne Department of Surgery, St. Vincent's Hospital, Fitzroy, Victoria, Australia

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April 2015

The proliferative gene cyclin D1 and gluconeogenesis--could suppressing glucose production also promote cancer?

Diabetes 2014 Oct;63(10):3177-9

Department of Medicine, University of Melbourne, Heidelberg, Victoria, Australia

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October 2014

Hepatic oxidative stress promotes insulin-STAT-5 signaling and obesity by inactivating protein tyrosine phosphatase N2.

Cell Metab 2014 Jul 19;20(1):85-102. Epub 2014 Jun 19.

Department of Biochemistry and Molecular Biology, Monash University, Wellington Road, Clayton, VIC 3800, Australia. Electronic address:

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July 2014

Hope and fear for new classes of type 2 diabetes drugs: is there preclinical evidence that incretin-based therapies alter pancreatic morphology?

J Endocrinol 2014 Apr 7;221(1):T43-61. Epub 2014 Mar 7.

Department of Medicine (Austin Health), The University of Melbourne, Melbourne, Victoria, Australia.

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April 2014

Exercise-induced muscle glucose uptake in mice with graded, muscle-specific GLUT-4 deletion.

Physiol Rep 2013 Aug 22;1(3):e00065. Epub 2013 Aug 22.

School of Exercise and Nutrition Sciences, Deakin University Geelong, Victoria, Australia.

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August 2013

The liver: Key in regulating appetite and body weight.

Adipocyte 2012 Oct;1(4):259-264

Department of Medicine (Austin Health); University of Melbourne; Heidelberg, VIC Australia.

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October 2012

Neprilysin deficiency protects against fat-induced insulin secretory dysfunction by maintaining calcium influx.

Diabetes 2013 May 17;62(5):1593-601. Epub 2013 Jan 17.

Department of Medicine, VA Puget Sound Health Care System and University of Washington, Seattle, Washington, USA.

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May 2013

Glucose homeostasis can be differentially modulated by varying individual components of a western diet.

J Nutr Biochem 2013 Jul 11;24(7):1251-7. Epub 2013 Jan 11.

Diabetes Complications, Baker IDI Heart and Diabetes Research Institute, Melbourne, Victoria, Australia.

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July 2013

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes.

Nature 2012 Oct 26;490(7420):426-30. Epub 2012 Sep 26.

Tissue Biology Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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October 2012

High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation.

PLoS One 2012 13;7(7):e40868. Epub 2012 Jul 13.

Diabetes and Transcription Factors Group, Garvan Institute of Medical Research, Sydney, NSW, Australia.

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January 2013

Normal muscle glucose uptake in mice deficient in muscle GLUT4.

J Endocrinol 2012 Sep 26;214(3):313-27. Epub 2012 Jun 26.

Department of Medicine (Austin Health), Austin Hospital, University of Melbourne, Heidelberg, Victoria 3084, Australia.

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September 2012

The nuclear receptor, Nor-1, markedly increases type II oxidative muscle fibers and resistance to fatigue.

Mol Endocrinol 2012 Mar 26;26(3):372-84. Epub 2012 Jan 26.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia.

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March 2012

Hypoxanthine-xanthine oxidase down-regulates GLUT1 transcription via SIRT1 resulting in decreased glucose uptake in human placenta.

J Endocrinol 2012 Apr 19;213(1):49-57. Epub 2012 Jan 19.

Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, Level 4/163 Studley Road, Heidelberg, Victoria, Australia.

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April 2012

Deficiency in interferon-gamma results in reduced body weight and better glucose tolerance in mice.

Endocrinology 2011 Oct 26;152(10):3690-9. Epub 2011 Jul 26.

University of Melbourne, Department of Medicine (Austin Health and Northern Health), Heidelberg Repatriation Hospital, 300 Waterdale Road, Heidelberg Heights, Victoria 3081, Australia.

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October 2011

A primary defect in glucose production alone cannot induce glucose intolerance without defects in insulin secretion.

J Endocrinol 2011 Sep 23;210(3):335-47. Epub 2011 Jun 23.

Department of Medicine, Heidelberg Repatriation Hospital, University of Melbourne, 300 Waterdale Road, Heidelberg Heights, Melbourne, Victoria 3081, Australia.

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September 2011

The New Zealand obese mouse model of obesity insulin resistance and poor breeding performance: evaluation of ovarian structure and function.

J Endocrinol 2011 Jun 23;209(3):307-15. Epub 2011 Mar 23.

Department of Medicine (Austin Health/Northern Health), Heidelberg Repatriation Hospital, The University of Melbourne, Heidelberg Heights, Melbourne, Victoria 3081, Australia.

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June 2011

Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy.

Am J Physiol Renal Physiol 2010 Mar 16;298(3):F763-70. Epub 2009 Dec 16.

Juvenile Diabetes Research Foundation Einstein Centre for Diabetic Complications, Baker International Diabetes Institute Heart and Diabetes Research Institute, Melbourne, Victoria, Australia.

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March 2010

The deletion variant of nicotinamide nucleotide transhydrogenase (Nnt) does not affect insulin secretion or glucose tolerance.

Endocrinology 2010 Jan 11;151(1):96-102. Epub 2009 Nov 11.

University of Melbourne, Department of Medicine, Heidelberg Repatriation Hospital, Heidelberg Heights, Victoria 3081, Australia.

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January 2010

Evaluating the glucose tolerance test in mice.

Am J Physiol Endocrinol Metab 2008 Dec 23;295(6):E1323-32. Epub 2008 Sep 23.

Univ. of Melbourne, Dept. of Medicine, Heidelberg Heights, Victoria, Australia.

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December 2008

Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in the liver.

Am J Physiol Endocrinol Metab 2008 Nov 9;295(5):E1132-41. Epub 2008 Sep 9.

Department of Medicine, Austin Health and Northern Health, University of Melbourne, Heidelberg Heights, Australia.

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November 2008

In vivo quantification of fat content in mice using the Hologic QDR 4500A densitometer.

Obes Res Clin Pract 2007 Jan;1(1):1-78

Royal Melbourne Hospital Bone and Mineral Service, C/- The Royal Melbourne Hospital, Parkville, Vic. 3050, Australia. Electronic

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January 2007

Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis.

Endocrinology 2006 Jun 23;147(6):2764-72. Epub 2006 Feb 23.

Department of Medicine (Austin Health and Northern Health), University of Melbourne, Heidelberg Repatriation Hospital, Heidelberg Heights, Victoria 3081, Australia.

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June 2006

Investigational agents that protect pancreatic islet beta-cells from failure.

Expert Opin Investig Drugs 2005 Oct;14(10):1241-50

Department of Medicine (AH/NH), Heidelberg Repatriation Hospital, University of Melbourne, Heidelberg Heights, Victoria 3081, Australia.

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October 2005

Socs1 deficiency enhances hepatic insulin signaling.

J Biol Chem 2005 Sep 27;280(36):31516-21. Epub 2005 Jun 27.

St. Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065, Australia.

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September 2005

Molecular mechanisms of increased glucose production: identifying potential therapeutic targets.

J Investig Med 2004 Sep;52(6):389-93

Department of Medicine, Repatriation Hospital, Heidelberg, Australia.

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September 2004

Metabolic adaptations of three inbred strains of mice (C57BL/6, DBA/2, and 129T2) in response to a high-fat diet.

J Nutr 2004 Dec;134(12):3264-9

The University of Melbourne, Department of Medicine, (AH/NH), Heidelberg Repatriation Hospital, Heidelberg Heights, Victoria 3081 Australia.

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December 2004

Elevated SNAP-25 is associated with fatty acid-induced impairment of mouse islet function.

Biochem Biophys Res Commun 2004 Apr;317(2):472-7

Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Parkville, Vic. 3050, Australia.

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April 2004

Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.

Am J Physiol Endocrinol Metab 2004 Mar 12;286(3):E418-24. Epub 2003 Nov 12.

Department of Medicine, Veterans Affairs Puget Sound Health Care System and University of Washington, Seattle, Washington, USA.

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March 2004

Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.

Diabetes 2003 Feb;52(2):372-9

Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, VA Puget Sound Health Care System and University of Washington, Seattle 98108, USA.

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February 2003

The hexosamine biosynthesis pathway regulates insulin secretion via protein glycosylation in mouse islets.

Arch Biochem Biophys 2002 Sep;405(2):275-9

Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Parkville, Vic. 3050, Australia.

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September 2002