Sissel Lund-Katz

Sissel Lund-Katz

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Sissel Lund-Katz

Sissel Lund-Katz

Publications by authors named "Sissel Lund-Katz"

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Helical structure, stability, and dynamics in human apolipoprotein E3 and E4 by hydrogen exchange and mass spectrometry.

Proc Natl Acad Sci U S A 2017 01 17;114(5):968-973. Epub 2017 Jan 17.

Division of Translational Medicine and Human Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-5158;

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http://dx.doi.org/10.1073/pnas.1617523114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293021PMC
January 2017

The roles of C-terminal helices of human apolipoprotein A-I in formation of high-density lipoprotein particles.

Biochim Biophys Acta 2014 Jan 9;1841(1):80-7. Epub 2013 Oct 9.

Institute of Health Biosciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima 770-8505, Japan; Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima 770-8505, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2013.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863607PMC
January 2014

Interaction of thioflavin T with amyloid fibrils of apolipoprotein A-I N-terminal fragment: resonance energy transfer study.

J Struct Biol 2014 Jan 15;185(1):116-24. Epub 2013 Nov 15.

Institute of Health Biosciences, Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima 770-8505, Japan.

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http://dx.doi.org/10.1016/j.jsb.2013.10.017DOI Listing
January 2014

Mechanisms responsible for the compositional heterogeneity of nascent high density lipoprotein.

J Biol Chem 2013 Aug 8;288(32):23150-60. Epub 2013 Jul 8.

Lipid Research Group, The Children's Hospital of Philadelphia, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://www.jbc.org/content/early/2013/07/08/jbc.M113.495523.
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http://www.jbc.org/cgi/doi/10.1074/jbc.M113.495523
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http://dx.doi.org/10.1074/jbc.M113.495523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743487PMC
August 2013

Comparison of apoA-I helical structure and stability in discoidal and spherical HDL particles by HX and mass spectrometry.

J Lipid Res 2013 Jun 10;54(6):1589-97. Epub 2013 Apr 10.

Lipid Research Group, Gastroenterology, Hepatology, and Nutrition Division, Children's Hospital of Philadelphia, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1194/jlr.M034785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646460PMC
June 2013

Molecular mechanisms responsible for the differential effects of apoE3 and apoE4 on plasma lipoprotein-cholesterol levels.

Arterioscler Thromb Vasc Biol 2013 Apr 14;33(4):687-93. Epub 2013 Feb 14.

Institute for Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1161/ATVBAHA.112.301193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660844PMC
April 2013

Apolipoprotein E-mediated cell cycle arrest linked to p27 and the Cox2-dependent repression of miR221/222.

Atherosclerosis 2013 Mar 19;227(1):65-71. Epub 2012 Dec 19.

Department of Pharmacology, University of Pennsylvania Perelman School of Medicine, 3620 Hamilton Walk, Philadelphia, PA 19104-6084, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638207PMC
March 2013

Interactions of apolipoprotein A-I with high-density lipoprotein particles.

Biochemistry 2013 Mar 4;52(11):1963-72. Epub 2013 Mar 4.

Lipid Research Group, Gastroenterology, Hepatology and Nutrition Division, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104-4318, United States.

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http://dx.doi.org/10.1021/bi400032yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603221PMC
March 2013

Dual role of an N-terminal amyloidogenic mutation in apolipoprotein A-I: destabilization of helix bundle and enhancement of fibril formation.

J Biol Chem 2013 Jan 11;288(4):2848-56. Epub 2012 Dec 11.

Institute of Health Biosciences and Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima 770-8505, Japan.

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http://dx.doi.org/10.1074/jbc.M112.428052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554949PMC
January 2013

Effects of the Iowa and Milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry.

Biochemistry 2012 Nov 24;51(44):8993-9001. Epub 2012 Oct 24.

Lipid Research Group, Gastroenterology, Hepatology and Nutrition Division, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104-4318, United States.

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http://dx.doi.org/10.1021/bi300926jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493162PMC
November 2012

Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening.

Cell Rep 2012 Nov 25;2(5):1259-71. Epub 2012 Oct 25.

Institute for Translational Medicine and Therapeutics, Departments of Pharmacology, Medicine, and Physiology, and the Molecular Profiling Facility, University of Pennsylvania, Philadelphia, PA 19104, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S22111247120032
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http://dx.doi.org/10.1016/j.celrep.2012.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535179PMC
November 2012

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.

J Clin Invest 2012 Aug 2;122(8):2807-16. Epub 2012 Jul 2.

Institute for Translational Medicine and Therapeutics, Cardiovascular Institute, and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://www.jci.org/articles/view/63563
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http://dx.doi.org/10.1172/JCI63563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408750PMC
August 2012

Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4.

Biochemistry 2012 Jul 3;51(28):5580-8. Epub 2012 Jul 3.

Institute of Health Biosciences and Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima 770-8505, Japan.

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http://dx.doi.org/10.1021/bi300672sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447985PMC
July 2012

Apolipoprotein A-I helical structure and stability in discoidal high-density lipoprotein (HDL) particles by hydrogen exchange and mass spectrometry.

Proc Natl Acad Sci U S A 2012 Jul 27;109(29):11687-92. Epub 2012 Jun 27.

Lipid Research Group, Gastroenterology, Hepatology and Nutrition Division, Children's Hospital of Philadelphia, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1073/pnas.1209305109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406875PMC
July 2012

Influence of C-terminal α-helix hydrophobicity and aromatic amino acid content on apolipoprotein A-I functionality.

Biochim Biophys Acta 2012 Mar 5;1821(3):456-63. Epub 2011 Aug 5.

Lipid Research Group, Gastroenterology, Hepatology and Nutrition Division, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S138819811100145
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http://dx.doi.org/10.1016/j.bbalip.2011.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227795PMC
March 2012

LDL-based nanoparticles for contrast enhanced MRI of atheroplaques in mouse models.

Chem Commun (Camb) 2011 Aug 8;47(31):8835-7. Epub 2011 Jul 8.

Laboratories of Molecular Imaging, Department of Radiology, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104-6323, USA.

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http://dx.doi.org/10.1039/c1cc10924cDOI Listing
August 2011

Influence of N-terminal helix bundle stability on the lipid-binding properties of human apolipoprotein A-I.

Biochim Biophys Acta 2011 Jan 30;1811(1):25-30. Epub 2010 Oct 30.

Department of Biophysical Chemistry, Kobe Pharmaceutical University, Kobe 658-8558, Japan.

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http://dx.doi.org/10.1016/j.bbalip.2010.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003738PMC
January 2011

Molecular basis for the differences in lipid and lipoprotein binding properties of human apolipoproteins E3 and E4.

Biochemistry 2010 Dec 3;49(51):10881-9. Epub 2010 Dec 3.

Lipid Research Group, Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, United States.

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http://dx.doi.org/10.1021/bi1017655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025481PMC
December 2010

Influence of apolipoprotein (Apo) A-I structure on nascent high density lipoprotein (HDL) particle size distribution.

J Biol Chem 2010 Oct 2;285(42):31965-73. Epub 2010 Aug 2.

Lipid Research Group, Gastroenterology, Hepatology, and Nutrition Division, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.126292
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http://dx.doi.org/10.1074/jbc.M110.126292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952197PMC
October 2010

High density lipoprotein structure-function and role in reverse cholesterol transport.

Subcell Biochem 2010 ;51:183-227

Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1007/978-90-481-8622-8_7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215094PMC
May 2010

Surface plasmon resonance analysis of the mechanism of binding of apoA-I to high density lipoprotein particles.

J Lipid Res 2010 Mar 28;51(3):606-17. Epub 2009 Sep 28.

Lipid Research Group, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1194/jlr.M002055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817590PMC
March 2010

Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages.

Arterioscler Thromb Vasc Biol 2010 Mar 17;30(3):526-32. Epub 2009 Dec 17.

Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Maloney Building, Room 8039, 3600 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1161/ATVBAHA.109.196105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842952PMC
March 2010

Helical structure and stability in human apolipoprotein A-I by hydrogen exchange and mass spectrometry.

Proc Natl Acad Sci U S A 2009 Nov 22;106(45):19005-10. Epub 2009 Oct 22.

Lipid Research Group, Gastroenterology, Hepatology and Nutrition Division, Children's Hospital of Philadelphia, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1073/pnas.0909708106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776417PMC
November 2009

Mechanism underlying apolipoprotein E (ApoE) isoform-dependent lipid efflux from neural cells in culture.

J Neurosci Res 2009 Aug;87(11):2498-508

Department of Alzheimer's Disease Research, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.

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http://dx.doi.org/10.1002/jnr.22073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065888PMC
August 2009

Molecular mechanism of apolipoprotein E binding to lipoprotein particles.

Biochemistry 2009 Apr;48(13):3025-32

Lipid Research Group, Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1021/bi9000694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765560PMC
April 2009

Lipoprotein nanoplatform for targeted delivery of diagnostic and therapeutic agents.

Adv Exp Med Biol 2009 ;645:227-39

Molecular Imaging Laboratory, Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6069, USA.

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http://link.springer.com/10.1007/978-0-387-85998-9_35
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http://dx.doi.org/10.1007/978-0-387-85998-9_35DOI Listing
March 2009

Interaction between the N- and C-terminal domains modulates the stability and lipid binding of apolipoprotein A-I.

Biochemistry 2009 Mar;48(11):2529-37

Department of Biophysical Chemistry, Kobe Pharmaceutical University, 4-19-1 Motoyamakitamachi, Higashinada-ku, Kobe 658-8558, Japan.

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http://dx.doi.org/10.1021/bi802317vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936823PMC
March 2009

Lipoprotein nanoplatform for targeted delivery of diagnostic and therapeutic agents.

Mol Imaging 2008 Mar-Apr;7(2):101-10

Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104-6069, USA.

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November 2008

Characterization and properties of pre beta-HDL particles formed by ABCA1-mediated cellular lipid efflux to apoA-I.

J Lipid Res 2008 May 5;49(5):1006-14. Epub 2008 Feb 5.

Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://www.jlr.org/content/49/5/1006.full.pdf
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http://www.jlr.org/cgi/doi/10.1194/jlr.M700506-JLR200
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http://dx.doi.org/10.1194/jlr.M700506-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2311446PMC
May 2008

Influence of tertiary structure domain properties on the functionality of apolipoprotein A-I.

Biochemistry 2008 Feb 19;47(7):2172-80. Epub 2008 Jan 19.

Department of Biophysical Chemistry, Kobe Pharmaceutical University, Kobe 658-8558, Japan.

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http://dx.doi.org/10.1021/bi702332bDOI Listing
February 2008

Structure-function properties of the apoE-dependent COX-2 pathway in vascular smooth muscle cells.

Atherosclerosis 2008 Jan 25;196(1):201-9. Epub 2007 May 25.

Institute for Translational Medicine and Therapeutics, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2007.03.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328805PMC
January 2008

Wild-type ApoA-I and the Milano variant have similar abilities to stimulate cellular lipid mobilization and efflux.

Arterioscler Thromb Vasc Biol 2007 Sep 5;27(9):2022-9. Epub 2007 Jul 5.

Division of Gasteroenterology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA.

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http://dx.doi.org/10.1161/ATVBAHA.107.148403DOI Listing
September 2007

Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles.

J Biol Chem 2007 Aug 29;282(34):25123-30. Epub 2007 Jun 29.

Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M704590200
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http://dx.doi.org/10.1074/jbc.M704590200DOI Listing
August 2007

ABCA1-induced cell surface binding sites for ApoA-I.

Arterioscler Thromb Vasc Biol 2007 Jul 3;27(7):1603-9. Epub 2007 May 3.

Division of GI/Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://atvb.ahajournals.org/content/27/7/1603.full.pdf
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http://atvb.ahajournals.org/cgi/doi/10.1161/ATVBAHA.107.1457
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http://dx.doi.org/10.1161/ATVBAHA.107.145789DOI Listing
July 2007

The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins.

Biochemistry 2007 Mar 17;46(10):2583-93. Epub 2007 Feb 17.

GI/Nutrition Division, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1021/bi602407rDOI Listing
March 2007

Contributions of the N- and C-terminal helical segments to the lipid-free structure and lipid interaction of apolipoprotein A-I.

Biochemistry 2006 Aug;45(34):10351-8

Department of Biophysical Chemistry, Kobe Pharmaceutical University, Kobe 658-8558, Japan.

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http://dx.doi.org/10.1021/bi060726tDOI Listing
August 2006

Low-density lipoprotein nanoparticles as magnetic resonance imaging contrast agents.

Neoplasia 2006 Jun;8(6):488-98

Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1593/neo.05835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1601463PMC
June 2006

Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I.

J Lipid Res 2006 Apr 17;47(4):832-43. Epub 2006 Jan 17.

Division of GI/Nutrition, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://www.jlr.org/content/47/4/832.full.pdf
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http://www.jlr.org/cgi/doi/10.1194/jlr.M500531-JLR200
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http://dx.doi.org/10.1194/jlr.M500531-JLR200DOI Listing
April 2006

Effect of carboxyl-terminal truncation on structure and lipid interaction of human apolipoprotein E4.

Biochemistry 2006 Apr;45(13):4240-7

Department of Biophysical Chemistry, Kobe Pharmaceutical University, Kobe 658-8558, Japan.

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http://pubs.acs.org/doi/abs/10.1021/bi060023b
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http://dx.doi.org/10.1021/bi060023bDOI Listing
April 2006

Structural analysis of lipoprotein E particles.

Biochemistry 2005 Sep;44(37):12525-34

University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1021/bi050872jDOI Listing
September 2005

Effects of the core lipid on the energetics of binding of ApoA-I to model lipoprotein particles of different sizes.

Biochemistry 2005 Aug;44(31):10689-95

The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1021/bi050853+DOI Listing
August 2005

Two-step mechanism of binding of apolipoprotein E to heparin: implications for the kinetics of apolipoprotein E-heparan sulfate proteoglycan complex formation on cell surfaces.

J Biol Chem 2005 Feb 6;280(7):5414-22. Epub 2004 Dec 6.

Lipid Research Group, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1074/jbc.M411719200DOI Listing
February 2005

Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids.

J Biol Chem 2004 Nov 21;279(48):49931-9. Epub 2004 Sep 21.

Division of GI/Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1074/jbc.M406924200DOI Listing
November 2004

MR and fluorescent imaging of low-density lipoprotein receptors.

Acad Radiol 2004 Nov;11(11):1251-9

Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.acra.2004.08.007DOI Listing
November 2004

Structure of human apolipoprotein A-IV: a distinct domain architecture among exchangeable apolipoproteins with potential functional implications.

Biochemistry 2004 Aug;43(33):10719-29

Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, Ohio 45267, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi048978m
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August 2004

Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins.

Prog Lipid Res 2004 Jul;43(4):350-80

Lipid Research Group, The Children's Hospital of Philadelphia, Abramson Research Center, Suite 1102, 3615 Civic Center Boulevard, University of Pennsylvania School of Medicine, Philadelphia, 19104-4318, USA.

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http://dx.doi.org/10.1016/j.plipres.2004.05.002DOI Listing
July 2004

Carbocyanine labeled LDL for optical imaging of tumors.

Acad Radiol 2004 Jun;11(6):669-77

Department of Radiology, University of Pennsylvania Medical School, Chemistry 1958 Wing, Room 284, Box 66, 250 South 33rd Street, Philadelphia, PA 19104 USA.

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http://dx.doi.org/10.1016/j.acra.2004.01.016DOI Listing
June 2004

Alpha-helix formation is required for high affinity binding of human apolipoprotein A-I to lipids.

J Biol Chem 2004 May 12;279(20):20974-81. Epub 2004 Mar 12.

Division of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Abramson Research Center, 3625 Civic Center Boulevard, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1074/jbc.M402043200DOI Listing
May 2004

Helix orientation of the functional domains in apolipoprotein e in discoidal high density lipoprotein particles.

J Biol Chem 2004 Apr 21;279(14):14273-9. Epub 2004 Jan 21.

Lipid Biology in Health and Disease Research Group, Children's Hospital Oakland Research Institute, Oakland, California 94609, USA.

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http://dx.doi.org/10.1074/jbc.M313318200DOI Listing
April 2004

Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure.

J Biol Chem 2004 Mar 12;279(13):12448-55. Epub 2004 Jan 12.

Division of GI/Nutrition, Lipid Research Group, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 3615 Civic Center Boulevard, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1074/jbc.M311718200DOI Listing
March 2004

Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein.

Mol Biol Cell 2004 Jan 3;15(1):384-96. Epub 2003 Oct 3.

Department of Pharmacological Sciences, University Medical Center, State University of New York at Stony Brook, Stony Brook, New York 11794, USA.

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http://dx.doi.org/10.1091/mbc.e03-06-0445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC307555PMC
January 2004

Effects of polymorphism on the lipid interaction of human apolipoprotein E.

J Biol Chem 2003 Oct 12;278(42):40723-9. Epub 2003 Aug 12.

National Institute of Health Sciences, Osaka Branch, Osaka 540-0006, Japan.

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http://dx.doi.org/10.1074/jbc.M304814200DOI Listing
October 2003

Effects of apolipoprotein A-I on ATP-binding cassette transporter A1-mediated efflux of macrophage phospholipid and cholesterol: formation of nascent high density lipoprotein particles.

J Biol Chem 2003 Oct 19;278(44):42976-84. Epub 2003 Aug 19.

Gastrointestinal/Nutrition Division, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1074/jbc.M308420200DOI Listing
October 2003

Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase.

Circulation 2003 Oct 29;108(17):2121-6. Epub 2003 Sep 29.

Departments of Medicine, University of Pennsylvania, Philadelphia, Pa, USA.

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http://dx.doi.org/10.1161/01.CIR.0000092889.24713.DCDOI Listing
October 2003

A quantitative analysis of apolipoprotein binding to SR-BI: multiple binding sites for lipid-free and lipid-associated apolipoproteins.

J Lipid Res 2003 Jun 1;44(6):1132-42. Epub 2003 Apr 1.

Division of GI/Nutrition, Lipid Research Group, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 19104-4318, USA.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M200429-JLR200
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http://dx.doi.org/10.1194/jlr.M200429-JLR200DOI Listing
June 2003

Domain structure and lipid interaction in human apolipoproteins A-I and E, a general model.

J Biol Chem 2003 Jun 22;278(26):23227-32. Epub 2003 Apr 22.

National Institute of Health Sciences, Osaka Branch, Osaka 540-0006, Japan.

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http://dx.doi.org/10.1074/jbc.M303365200DOI Listing
June 2003

High density lipoprotein structure.

Front Biosci 2003 May 1;8:d1044-54. Epub 2003 May 1.

GI/Nutrition Division, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.2741/1077DOI Listing
May 2003

Characterization of the heparin binding sites in human apolipoprotein E.

J Biol Chem 2003 Apr 14;278(17):14782-7. Epub 2003 Feb 14.

Joseph Stokes, Jr. Research Institute, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1074/jbc.M213207200DOI Listing
April 2003

Low-density lipoprotein reconstituted by pyropheophorbide cholesteryl oleate as target-specific photosensitizer.

Bioconjug Chem 2002 May-Jun;13(3):392-6

Department of Radiology, University of Pennsylvania Medical School, Philadelphia 19104, USA.

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December 2002

Influence of apoE domain structure and polymorphism on the kinetics of phospholipid vesicle solubilization.

J Lipid Res 2002 Oct;43(10):1688-700

Joseph Stokes Jr. Research Institute, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1194/jlr.m200157-jlr200DOI Listing
October 2002

Comparison of the stabilities and unfolding pathways of human apolipoprotein E isoforms by differential scanning calorimetry and circular dichroism.

Biochim Biophys Acta 2002 Sep;1584(1):9-19

Department of Chemistry and Biochemistry, University of the Sciences in Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/s1388-1981(02)00263-9DOI Listing
September 2002

Human secretory phospholipase A2 mediates decreased plasma levels of HDL cholesterol and apoA-I in response to inflammation in human apoA-I transgenic mice.

Arterioscler Thromb Vasc Biol 2002 Jul;22(7):1213-8

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pa, USA.

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http://dx.doi.org/10.1161/01.atv.0000023228.90866.29DOI Listing
July 2002