Simonetta Guarrera

Simonetta Guarrera

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Simonetta Guarrera

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Peripheral Blood DNA Methylation as Potential Biomarker of Malignant Pleural Mesothelioma in Asbestos-Exposed Subjects.

J Thorac Oncol 2019 Mar 5;14(3):527-539. Epub 2018 Nov 5.

Italian Institute for Genomic Medicine, IIGM, Turin, Italy; Department of Medical Sciences, University of Turin, Turin, Italy; Interdepartmental Center for Studies on Asbestos and Other Toxic Particulates "G. Scansetti," University of Turin, Turin, Italy; Medical Genetics Unit, AOU Città della Salute e della Scienza, Turin, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864183341
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http://dx.doi.org/10.1016/j.jtho.2018.10.163DOI Listing
March 2019

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults.

EBioMedicine 2018 Dec 13;38:206-216. Epub 2018 Nov 13.

Center for Life Course Health Research, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland; Medical Research Centre (MRC) Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964183048
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http://dx.doi.org/10.1016/j.ebiom.2018.10.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306313PMC
December 2018

Germline mutations in DNA repair genes predispose asbestos-exposed patients to malignant pleural mesothelioma.

Cancer Lett 2017 10 4;405:38-45. Epub 2017 Jul 4.

Department of Health Sciences, University of Piemonte Orientale, Novara, Italy; Interdepartmental Center for Studies on Asbestos and Other Toxic Particulates "G. Scansetti", University of Turin, Turin, Italy.

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http://dx.doi.org/10.1016/j.canlet.2017.06.028DOI Listing
October 2017

Telomerase activity, telomere length and hTERT DNA methylation in peripheral blood mononuclear cells from monozygotic twins with discordant smoking habits.

Environ Mol Mutagen 2017 10 26;58(8):551-559. Epub 2017 Aug 26.

Department of Environment and Primary Prevention, Surveillance and Health Promotion, Istituto Superiore di Sanità, V.le Regina Elena 299, Rome, 00161, Italy.

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http://doi.wiley.com/10.1002/em.22127
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http://dx.doi.org/10.1002/em.22127DOI Listing
October 2017

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

Authors:
Amand F Schmidt Daniel I Swerdlow Michael V Holmes Riyaz S Patel Zammy Fairhurst-Hunter Donald M Lyall Fernando Pires Hartwig Bernardo Lessa Horta Elina Hyppönen Christine Power Max Moldovan Erik van Iperen G Kees Hovingh Ilja Demuth Kristina Norman Elisabeth Steinhagen-Thiessen Juri Demuth Lars Bertram Tian Liu Stefan Coassin Johann Willeit Stefan Kiechl Karin Willeit Dan Mason John Wright Richard Morris Goya Wanamethee Peter Whincup Yoav Ben-Shlomo Stela McLachlan Jackie F Price Mika Kivimaki Catherine Welch Adelaida Sanchez-Galvez Pedro Marques-Vidal Andrew Nicolaides Andrie G Panayiotou N Charlotte Onland-Moret Yvonne T van der Schouw Giuseppe Matullo Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Nicholas J Wareham Claudia Langenberg Robert Scott Jian'an Luan Martin Bobak Sofia Malyutina Andrzej Pająk Ruzena Kubinova Abdonas Tamosiunas Hynek Pikhart Lise Lotte Nystrup Husemoen Niels Grarup Oluf Pedersen Torben Hansen Allan Linneberg Kenneth Starup Simonsen Jackie Cooper Steve E Humphries Murray Brilliant Terrie Kitchner Hakon Hakonarson David S Carrell Catherine A McCarty H Lester Kirchner Eric B Larson David R Crosslin Mariza de Andrade Dan M Roden Joshua C Denny Cara Carty Stephen Hancock John Attia Elizabeth Holliday Martin O'Donnell Salim Yusuf Michael Chong Guillaume Pare Pim van der Harst M Abdullah Said Ruben N Eppinga Niek Verweij Harold Snieder Tim Christen Dennis O Mook-Kanamori Stefan Gustafsson Lars Lind Erik Ingelsson Raha Pazoki Oscar Franco Albert Hofman Andre Uitterlinden Abbas Dehghan Alexander Teumer Sebastian Baumeister Marcus Dörr Markus M Lerch Uwe Völker Henry Völzke Joey Ward Jill P Pell Daniel J Smith Tom Meade Anke H Maitland-van der Zee Ekaterina V Baranova Robin Young Ian Ford Archie Campbell Sandosh Padmanabhan Michiel L Bots Diederick E Grobbee Philippe Froguel Dorothée Thuillier Beverley Balkau Amélie Bonnefond Bertrand Cariou Melissa Smart Yanchun Bao Meena Kumari Anubha Mahajan Paul M Ridker Daniel I Chasman Alex P Reiner Leslie A Lange Marylyn D Ritchie Folkert W Asselbergs Juan-Pablo Casas Brendan J Keating David Preiss Aroon D Hingorani Naveed Sattar

Lancet Diabetes Endocrinol 2017 02 29;5(2):97-105. Epub 2016 Nov 29.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(16)30396-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266795PMC
February 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Authors:
Simone Wahl Alexander Drong Benjamin Lehne Marie Loh William R Scott Sonja Kunze Pei-Chien Tsai Janina S Ried Weihua Zhang Youwen Yang Sili Tan Giovanni Fiorito Lude Franke Simonetta Guarrera Silva Kasela Jennifer Kriebel Rebecca C Richmond Marco Adamo Uzma Afzal Mika Ala-Korpela Benedetta Albetti Ole Ammerpohl Jane F Apperley Marian Beekman Pier Alberto Bertazzi S Lucas Black Christine Blancher Marc-Jan Bonder Mario Brosch Maren Carstensen-Kirberg Anton J M de Craen Simon de Lusignan Abbas Dehghan Mohamed Elkalaawy Krista Fischer Oscar H Franco Tom R Gaunt Jochen Hampe Majid Hashemi Aaron Isaacs Andrew Jenkinson Sujeet Jha Norihiro Kato Vittorio Krogh Michael Laffan Christa Meisinger Thomas Meitinger Zuan Yu Mok Valeria Motta Hong Kiat Ng Zacharoula Nikolakopoulou Georgios Nteliopoulos Salvatore Panico Natalia Pervjakova Holger Prokisch Wolfgang Rathmann Michael Roden Federica Rota Michelle Ann Rozario Johanna K Sandling Clemens Schafmayer Katharina Schramm Reiner Siebert P Eline Slagboom Pasi Soininen Lisette Stolk Konstantin Strauch E-Shyong Tai Letizia Tarantini Barbara Thorand Ettje F Tigchelaar Rosario Tumino Andre G Uitterlinden Cornelia van Duijn Joyce B J van Meurs Paolo Vineis Ananda Rajitha Wickremasinghe Cisca Wijmenga Tsun-Po Yang Wei Yuan Alexandra Zhernakova Rachel L Batterham George Davey Smith Panos Deloukas Bastiaan T Heijmans Christian Herder Albert Hofman Cecilia M Lindgren Lili Milani Pim van der Harst Annette Peters Thomas Illig Caroline L Relton Melanie Waldenberger Marjo-Riitta Järvelin Valentina Bollati Richie Soong Tim D Spector James Scott Mark I McCarthy Paul Elliott Jordana T Bell Giuseppe Matullo Christian Gieger Jaspal S Kooner Harald Grallert John C Chambers

Nature 2017 01 21;541(7635):81-86. Epub 2016 Dec 21.

Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.

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http://dx.doi.org/10.1038/nature20784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570525PMC
January 2017

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.

Genome Biol 2016 12 12;17(1):255. Epub 2016 Dec 12.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13059-016-1119-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151130PMC
December 2016

The Italian genome reflects the history of Europe and the Mediterranean basin.

Eur J Hum Genet 2016 07 11;24(7):1056-62. Epub 2015 Nov 11.

Department of Medical Sciences, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1038/ejhg.2015.233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070887PMC
July 2016

Association between Beta1 -Adrenergic Receptor Polymorphism and Risk of ICD Shock in Heart Failure Patients.

Pacing Clin Electrophysiol 2016 Jun 4;39(6):557-64. Epub 2016 May 4.

Department Medical Sciences, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1111/pace.12860DOI Listing
June 2016

Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry.

Authors:
Jonine D Figueroa Candace D Middlebrooks A Rouf Banday Yuanqing Ye Montserrat Garcia-Closas Nilanjan Chatterjee Stella Koutros Lambertus A Kiemeney Thorunn Rafnar Timothy Bishop Helena Furberg Giuseppe Matullo Klaus Golka Manuela Gago-Dominguez Jack A Taylor Tony Fletcher Afshan Siddiq Victoria K Cortessis Charles Kooperberg Olivier Cussenot Simone Benhamou Jennifer Prescott Stefano Porru Colin P Dinney Núria Malats Dalsu Baris Mark P Purdue Eric J Jacobs Demetrius Albanes Zhaoming Wang Charles C Chung Sita H Vermeulen Katja K Aben Tessel E Galesloot Gudmar Thorleifsson Patrick Sulem Kari Stefansson Anne E Kiltie Mark Harland Mark Teo Kenneth Offit Joseph Vijai Dean Bajorin Ryan Kopp Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Silvia Selinski Jan G Hengstler Holger Gerullis Daniel Ovsiannikov Meinolf Blaszkewicz Jose Esteban Castelao Manuel Calaza Maria Elena Martinez Patricia Cordeiro Zongli Xu Vijayalakshmi Panduri Rajiv Kumar Eugene Gurzau Kvetoslava Koppova H Bas Bueno-De-Mesquita Börje Ljungberg Françoise Clavel-Chapelon Elisabete Weiderpass Vittorio Krogh Miren Dorronsoro Ruth C Travis Anne Tjønneland Paul Brennan Jenny Chang-Claude Elio Riboli David Conti Marianna C Stern Malcolm C Pike David Van Den Berg Jian-Min Yuan Chancellor Hohensee Rebecca P Jeppson Geraldine Cancel-Tassin Morgan Roupret Eva Comperat Constance Turman Immaculata De Vivo Edward Giovannucci David J Hunter Peter Kraft Sara Lindstrom Angela Carta Sofia Pavanello Cecilia Arici Giuseppe Mastrangelo Ashish M Kamat Liren Zhang Yilei Gong Xia Pu Amy Hutchinson Laurie Burdett William A Wheeler Margaret R Karagas Alison Johnson Alan Schned G M Monawar Hosain Molly Schwenn Manolis Kogevinas Adonina Tardón Consol Serra Alfredo Carrato Reina García-Closas Josep Lloreta Gerald Andriole Robert Grubb Amanda Black W Ryan Diver Susan M Gapstur Stephanie Weinstein Jarmo Virtamo Christopher A Haiman Maria Teresa Landi Neil E Caporaso Joseph F Fraumeni Paolo Vineis Xifeng Wu Stephen J Chanock Debra T Silverman Ludmila Prokunina-Olsson Nathaniel Rothman

Hum Mol Genet 2016 Mar 4;25(6):1203-14. Epub 2016 Jan 4.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/hmg/ddv492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817084PMC
March 2016

Gene-asbestos interaction in malignant pleural mesothelioma susceptibility.

Carcinogenesis 2015 Oct 2;36(10):1129-35. Epub 2015 Jul 2.

Department of Translational Medicine, Unit of Medical Statistics and Cancer Epidemiology, CPO Piemonte and University of Piemonte Orientale, Novara, Italy, Interdepartmental Center "G. Scansetti", University of Turin, Turin, Italy.

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http://dx.doi.org/10.1093/carcin/bgv097DOI Listing
October 2015

Characterization of whole-genome autosomal differences of DNA methylation between men and women.

Epigenetics Chromatin 2015 19;8:43. Epub 2015 Oct 19.

Blavatnik School of Computer Science, Tel-Aviv University, Tel-Aviv, Israel ; Department of Molecular Microbiology and Biotechnology, George Wise Faculty of Life Science, Tel-Aviv University, Tel-Aviv, Israel ; International Computer Science Institute, Berkeley, CA USA.

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http://dx.doi.org/10.1186/s13072-015-0035-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615866PMC
October 2015

Epigenetic signatures of internal migration in Italy.

Int J Epidemiol 2015 08 15;44(4):1442-1449. Epub 2014 Oct 15.

Department of Epidemiology and Biostatistics, Imperial College London, London, UK,Human Genetics Foundation (HuGeF), Turin, Italy, Department of Medical Sciences, University of Turin, Turin, Italy, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy, Istituto per lo Studio e la Prevenzione Oncologica (ISPO Toscana), Florence, Italy, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy, Piedmont Reference Centre for Epidemiology and Cancer Prevention (CPO Piemonte), Turin, Italy Cancer Registry and Histopathology Unit, Azienda Ospedaliera 'Civile - M. P. Arezzo', Ragusa, Italy and MRC-PHE Centre for Environment and Health, Imperial College London, London, UK Department of Epidemiology and Biostatistics, Imperial College London, London, UK,Human Genetics Foundation (HuGeF), Turin, Italy, Department of Medical Sciences, University of Turin, Turin, Italy, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy, Istituto per lo Studio e la Prevenzione Oncologica (ISPO Toscana), Florence, Italy, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy, Piedmont Reference Centre for Epidemiology and Cancer Prevention (CPO Piemonte), Turin, Italy Cancer Registry and Histopathology Unit, Azienda Ospedaliera 'Civile - M. P. Arezzo', Ragusa, Italy and MRC-PHE Centre for Environment and Health, Imperial College London, London, UK Department of Epidemiology and Biostatistics, Imperial College London, London, UK,Human Genetics Foundation (HuGeF), Turin, Italy, Department of Medical Sciences, University of Turin, Turin, Italy, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy, Istituto per lo Studio e la Prevenzione Oncologica (ISPO Toscana), Florence, Italy, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy, Piedmont Reference Centre for Epidemiology and Cancer Prevention (CPO Piemonte), Turin, Italy Cancer Registry and Histopathology Unit, Azienda Ospedaliera 'Civile - M. P. Arezzo', Ragusa, Italy and MRC-PHE Centre for Environment and Health, Imperial College London, London, UK

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http://dx.doi.org/10.1093/ije/dyu198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588856PMC
August 2015

Shorter leukocyte telomere length is independently associated with poor survival in patients with bladder cancer.

Cancer Epidemiol Biomarkers Prev 2014 Nov 18;23(11):2439-46. Epub 2014 Sep 18.

Genomic Variation in Human Population and Complex Diseases Unit, Human Genetics Foundation, Turin, Italy. Department of Medical Sciences, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-0228DOI Listing
November 2014

Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer.

Hum Mol Genet 2014 Oct 26;23(20):5545-57. Epub 2014 May 26.

deCODE Genetics/AMGEN, Reykjavik 101, Iceland Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland

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http://dx.doi.org/10.1093/hmg/ddu264DOI Listing
October 2014

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.

PLoS Genet 2014 Jul 31;10(7):e1004508. Epub 2014 Jul 31.

Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1371/journal.pgen.1004508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117451PMC
July 2014

A genome-wide association study for malignant mesothelioma risk.

Lung Cancer 2013 Oct 1;82(1):1-8. Epub 2013 Jul 1.

Centre for Genetic Origins of Health and Disease, University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2013.04.018DOI Listing
October 2013

Next generation sequencing and rare genetic variants: from human population studies to medical genetics.

Environ Mol Mutagen 2013 Aug 6;54(7):518-32. Epub 2013 Aug 6.

Dipartimento di Scienze Mediche, Università di Torino, Torino, Italy.

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http://doi.wiley.com/10.1002/em.21799
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http://dx.doi.org/10.1002/em.21799DOI Listing
August 2013

Role of the 12q24.12 locus in the onset of preeclampsia: an Italian case-control study.

J Matern Fetal Neonatal Med 2012 Aug 29;25(8):1228-32. Epub 2011 Nov 29.

Department of Genetics, Biology and Biochemistry, University of Turin, Italy.

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http://dx.doi.org/10.3109/14767058.2011.636097DOI Listing
August 2012

Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase.

Hypertension 2012 Feb 19;59(2):248-55. Epub 2011 Dec 19.

Department of Medicine, Surgery, and Dentistry, Graduate School of Nephrology, University of Milano, Division of Nephrology, San Paolo Hospital, Milano, Viale Ortles 22/4, 20139 Milano, Italy.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.181990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272453PMC
February 2012

European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene.

Hum Mol Genet 2011 Nov 12;20(21):4268-81. Epub 2011 Jul 12.

deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1093/hmg/ddr303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188988PMC
November 2011

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

Authors:
Georg B Ehret Patricia B Munroe Kenneth M Rice Murielle Bochud Andrew D Johnson Daniel I Chasman Albert V Smith Martin D Tobin Germaine C Verwoert Shih-Jen Hwang Vasyl Pihur Peter Vollenweider Paul F O'Reilly Najaf Amin Jennifer L Bragg-Gresham Alexander Teumer Nicole L Glazer Lenore Launer Jing Hua Zhao Yurii Aulchenko Simon Heath Siim Sõber Afshin Parsa Jian'an Luan Pankaj Arora Abbas Dehghan Feng Zhang Gavin Lucas Andrew A Hicks Anne U Jackson John F Peden Toshiko Tanaka Sarah H Wild Igor Rudan Wilmar Igl Yuri Milaneschi Alex N Parker Cristiano Fava John C Chambers Ervin R Fox Meena Kumari Min Jin Go Pim van der Harst Wen Hong Linda Kao Marketa Sjögren D G Vinay Myriam Alexander Yasuharu Tabara Sue Shaw-Hawkins Peter H Whincup Yongmei Liu Gang Shi Johanna Kuusisto Bamidele Tayo Mark Seielstad Xueling Sim Khanh-Dung Hoang Nguyen Terho Lehtimäki Giuseppe Matullo Ying Wu Tom R Gaunt N Charlotte Onland-Moret Matthew N Cooper Carl G P Platou Elin Org Rebecca Hardy Santosh Dahgam Jutta Palmen Veronique Vitart Peter S Braund Tatiana Kuznetsova Cuno S P M Uiterwaal Adebowale Adeyemo Walter Palmas Harry Campbell Barbara Ludwig Maciej Tomaszewski Ioanna Tzoulaki Nicholette D Palmer Thor Aspelund Melissa Garcia Yen-Pei C Chang Jeffrey R O'Connell Nanette I Steinle Diederick E Grobbee Dan E Arking Sharon L Kardia Alanna C Morrison Dena Hernandez Samer Najjar Wendy L McArdle David Hadley Morris J Brown John M Connell Aroon D Hingorani Ian N M Day Debbie A Lawlor John P Beilby Robert W Lawrence Robert Clarke Jemma C Hopewell Halit Ongen Albert W Dreisbach Yali Li J Hunter Young Joshua C Bis Mika Kähönen Jorma Viikari Linda S Adair Nanette R Lee Ming-Huei Chen Matthias Olden Cristian Pattaro Judith A Hoffman Bolton Anna Köttgen Sven Bergmann Vincent Mooser Nish Chaturvedi Timothy M Frayling Muhammad Islam Tazeen H Jafar Jeanette Erdmann Smita R Kulkarni Stefan R Bornstein Jürgen Grässler Leif Groop Benjamin F Voight Johannes Kettunen Philip Howard Andrew Taylor Simonetta Guarrera Fulvio Ricceri Valur Emilsson Andrew Plump Inês Barroso Kay-Tee Khaw Alan B Weder Steven C Hunt Yan V Sun Richard N Bergman Francis S Collins Lori L Bonnycastle Laura J Scott Heather M Stringham Leena Peltonen Markus Perola Erkki Vartiainen Stefan-Martin Brand Jan A Staessen Thomas J Wang Paul R Burton Maria Soler Artigas Yanbin Dong Harold Snieder Xiaoling Wang Haidong Zhu Kurt K Lohman Megan E Rudock Susan R Heckbert Nicholas L Smith Kerri L Wiggins Ayo Doumatey Daniel Shriner Gudrun Veldre Margus Viigimaa Sanjay Kinra Dorairaj Prabhakaran Vikal Tripathy Carl D Langefeld Annika Rosengren Dag S Thelle Anna Maria Corsi Andrew Singleton Terrence Forrester Gina Hilton Colin A McKenzie Tunde Salako Naoharu Iwai Yoshikuni Kita Toshio Ogihara Takayoshi Ohkubo Tomonori Okamura Hirotsugu Ueshima Satoshi Umemura Susana Eyheramendy Thomas Meitinger H-Erich Wichmann Yoon Shin Cho Hyung-Lae Kim Jong-Young Lee James Scott Joban S Sehmi Weihua Zhang Bo Hedblad Peter Nilsson George Davey Smith Andrew Wong Narisu Narisu Alena Stančáková Leslie J Raffel Jie Yao Sekar Kathiresan Christopher J O'Donnell Stephen M Schwartz M Arfan Ikram W T Longstreth Thomas H Mosley Sudha Seshadri Nick R G Shrine Louise V Wain Mario A Morken Amy J Swift Jaana Laitinen Inga Prokopenko Paavo Zitting Jackie A Cooper Steve E Humphries John Danesh Asif Rasheed Anuj Goel Anders Hamsten Hugh Watkins Stephan J L Bakker Wiek H van Gilst Charles S Janipalli K Radha Mani Chittaranjan S Yajnik Albert Hofman Francesco U S Mattace-Raso Ben A Oostra Ayse Demirkan Aaron Isaacs Fernando Rivadeneira Edward G Lakatta Marco Orru Angelo Scuteri Mika Ala-Korpela Antti J Kangas Leo-Pekka Lyytikäinen Pasi Soininen Taru Tukiainen Peter Würtz Rick Twee-Hee Ong Marcus Dörr Heyo K Kroemer Uwe Völker Henry Völzke Pilar Galan Serge Hercberg Mark Lathrop Diana Zelenika Panos Deloukas Massimo Mangino Tim D Spector Guangju Zhai James F Meschia Michael A Nalls Pankaj Sharma Janos Terzic M V Kranthi Kumar Matthew Denniff Ewa Zukowska-Szczechowska Lynne E Wagenknecht F Gerald R Fowkes Fadi J Charchar Peter E H Schwarz Caroline Hayward Xiuqing Guo Charles Rotimi Michiel L Bots Eva Brand Nilesh J Samani Ozren Polasek Philippa J Talmud Fredrik Nyberg Diana Kuh Maris Laan Kristian Hveem Lyle J Palmer Yvonne T van der Schouw Juan P Casas Karen L Mohlke Paolo Vineis Olli Raitakari Santhi K Ganesh Tien Y Wong E Shyong Tai Richard S Cooper Markku Laakso Dabeeru C Rao Tamara B Harris Richard W Morris Anna F Dominiczak Mika Kivimaki Michael G Marmot Tetsuro Miki Danish Saleheen Giriraj R Chandak Josef Coresh Gerjan Navis Veikko Salomaa Bok-Ghee Han Xiaofeng Zhu Jaspal S Kooner Olle Melander Paul M Ridker Stefania Bandinelli Ulf B Gyllensten Alan F Wright James F Wilson Luigi Ferrucci Martin Farrall Jaakko Tuomilehto Peter P Pramstaller Roberto Elosua Nicole Soranzo Eric J G Sijbrands David Altshuler Ruth J F Loos Alan R Shuldiner Christian Gieger Pierre Meneton Andre G Uitterlinden Nicholas J Wareham Vilmundur Gudnason Jerome I Rotter Rainer Rettig Manuela Uda David P Strachan Jacqueline C M Witteman Anna-Liisa Hartikainen Jacques S Beckmann Eric Boerwinkle Ramachandran S Vasan Michael Boehnke Martin G Larson Marjo-Riitta Järvelin Bruce M Psaty Gonçalo R Abecasis Aravinda Chakravarti Paul Elliott Cornelia M van Duijn Christopher Newton-Cheh Daniel Levy Mark J Caulfield Toby Johnson

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.

Authors:
Gunter Schumann Lachlan J Coin Anbarasu Lourdusamy Pimphen Charoen Karen H Berger David Stacey Sylvane Desrivières Fazil A Aliev Anokhi A Khan Najaf Amin Yurii S Aulchenko Georgy Bakalkin Stephan J Bakker Beverley Balkau Joline W Beulens Ainhoa Bilbao Rudolf A de Boer Delphine Beury Michiel L Bots Elemi J Breetvelt Stéphane Cauchi Christine Cavalcanti-Proença John C Chambers Toni-Kim Clarke Norbert Dahmen Eco J de Geus Danielle Dick Francesca Ducci Alanna Easton Howard J Edenberg Tõnu Esko Tõnu Esk Alberto Fernández-Medarde Tatiana Foroud Nelson B Freimer Jean-Antoine Girault Diederick E Grobbee Simonetta Guarrera Daniel F Gudbjartsson Anna-Liisa Hartikainen Andrew C Heath Victor Hesselbrock Albert Hofman Jouke-Jan Hottenga Matti K Isohanni Jaakko Kaprio Kay-Tee Khaw Brigitte Kuehnel Jaana Laitinen Stéphane Lobbens Jian'an Luan Massimo Mangino Matthieu Maroteaux Giuseppe Matullo Mark I McCarthy Christian Mueller Gerjan Navis Mattijs E Numans Alejandro Núñez Dale R Nyholt Charlotte N Onland-Moret Ben A Oostra Paul F O'Reilly Miklos Palkovits Brenda W Penninx Silvia Polidoro Anneli Pouta Inga Prokopenko Fulvio Ricceri Eugenio Santos Johannes H Smit Nicole Soranzo Kijoung Song Ulla Sovio Michael Stumvoll Ida Surakk Thorgeir E Thorgeirsson Unnur Thorsteinsdottir Claire Troakes Thorarinn Tyrfingsson Anke Tönjes Cuno S Uiterwaal Andre G Uitterlinden Pim van der Harst Yvonne T van der Schouw Oliver Staehlin Nicole Vogelzangs Peter Vollenweider Gerard Waeber Nicholas J Wareham Dawn M Waterworth John B Whitfield Erich H Wichmann Gonneke Willemsen Jacqueline C Witteman Xin Yuan Guangju Zhai Jing H Zhao Weihua Zhang Nicholas G Martin Andres Metspalu Angela Doering James Scott Tim D Spector Ruth J Loos Dorret I Boomsma Vincent Mooser Leena Peltonen Kari Stefansson Cornelia M van Duijn Paolo Vineis Wolfgang H Sommer Jaspal S Kooner Rainer Spanagel Ulrike A Heberlein Marjo-Riitta Jarvelin Paul Elliott

Proc Natl Acad Sci U S A 2011 Apr 6;108(17):7119-24. Epub 2011 Apr 6.

Medical Research Council-Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College, London SE5 8AF, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1017288108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084048PMC
April 2011

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.

Authors:
Nathaniel Rothman Montserrat Garcia-Closas Nilanjan Chatterjee Nuria Malats Xifeng Wu Jonine D Figueroa Francisco X Real David Van Den Berg Giuseppe Matullo Dalsu Baris Michael Thun Lambertus A Kiemeney Paolo Vineis Immaculata De Vivo Demetrius Albanes Mark P Purdue Thorunn Rafnar Michelle A T Hildebrandt Anne E Kiltie Olivier Cussenot Klaus Golka Rajiv Kumar Jack A Taylor Jose I Mayordomo Kevin B Jacobs Manolis Kogevinas Amy Hutchinson Zhaoming Wang Yi-Ping Fu Ludmila Prokunina-Olsson Laurie Burdett Meredith Yeager William Wheeler Adonina Tardón Consol Serra Alfredo Carrato Reina García-Closas Josep Lloreta Alison Johnson Molly Schwenn Margaret R Karagas Alan Schned Gerald Andriole Robert Grubb Amanda Black Eric J Jacobs W Ryan Diver Susan M Gapstur Stephanie J Weinstein Jarmo Virtamo Victoria K Cortessis Manuela Gago-Dominguez Malcolm C Pike Mariana C Stern Jian-Min Yuan David J Hunter Monica McGrath Colin P Dinney Bogdan Czerniak Meng Chen Hushan Yang Sita H Vermeulen Katja K Aben J Alfred Witjes Remco R Makkinje Patrick Sulem Soren Besenbacher Kari Stefansson Elio Riboli Paul Brennan Salvatore Panico Carmen Navarro Naomi E Allen H Bas Bueno-de-Mesquita Dimitrios Trichopoulos Neil Caporaso Maria Teresa Landi Federico Canzian Borje Ljungberg Anne Tjonneland Francoise Clavel-Chapelon David T Bishop Mark T W Teo Margaret A Knowles Simonetta Guarrera Silvia Polidoro Fulvio Ricceri Carlotta Sacerdote Alessandra Allione Geraldine Cancel-Tassin Silvia Selinski Jan G Hengstler Holger Dietrich Tony Fletcher Peter Rudnai Eugen Gurzau Kvetoslava Koppova Sophia C E Bolick Ashley Godfrey Zongli Xu José I Sanz-Velez María D García-Prats Manuel Sanchez Gabriel Valdivia Stefano Porru Simone Benhamou Robert N Hoover Joseph F Fraumeni Debra T Silverman Stephen J Chanock

Nat Genet 2010 Nov 24;42(11):978-84. Epub 2010 Oct 24.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ng.687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049891PMC
November 2010

A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.

Nat Genet 2010 May 28;42(5):415-9. Epub 2010 Mar 28.

Department of Epidemiology, Biostatistics and Health Technology Assessment, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ng.558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923020PMC
May 2010

Genome-wide association study identifies eight loci associated with blood pressure.

Authors:
Christopher Newton-Cheh Toby Johnson Vesela Gateva Martin D Tobin Murielle Bochud Lachlan Coin Samer S Najjar Jing Hua Zhao Simon C Heath Susana Eyheramendy Konstantinos Papadakis Benjamin F Voight Laura J Scott Feng Zhang Martin Farrall Toshiko Tanaka Chris Wallace John C Chambers Kay-Tee Khaw Peter Nilsson Pim van der Harst Silvia Polidoro Diederick E Grobbee N Charlotte Onland-Moret Michiel L Bots Louise V Wain Katherine S Elliott Alexander Teumer Jian'an Luan Gavin Lucas Johanna Kuusisto Paul R Burton David Hadley Wendy L McArdle Morris Brown Anna Dominiczak Stephen J Newhouse Nilesh J Samani John Webster Eleftheria Zeggini Jacques S Beckmann Sven Bergmann Noha Lim Kijoung Song Peter Vollenweider Gerard Waeber Dawn M Waterworth Xin Yuan Leif Groop Marju Orho-Melander Alessandra Allione Alessandra Di Gregorio Simonetta Guarrera Salvatore Panico Fulvio Ricceri Valeria Romanazzi Carlotta Sacerdote Paolo Vineis Inês Barroso Manjinder S Sandhu Robert N Luben Gabriel J Crawford Pekka Jousilahti Markus Perola Michael Boehnke Lori L Bonnycastle Francis S Collins Anne U Jackson Karen L Mohlke Heather M Stringham Timo T Valle Cristen J Willer Richard N Bergman Mario A Morken Angela Döring Christian Gieger Thomas Illig Thomas Meitinger Elin Org Arne Pfeufer H Erich Wichmann Sekar Kathiresan Jaume Marrugat Christopher J O'Donnell Stephen M Schwartz David S Siscovick Isaac Subirana Nelson B Freimer Anna-Liisa Hartikainen Mark I McCarthy Paul F O'Reilly Leena Peltonen Anneli Pouta Paul E de Jong Harold Snieder Wiek H van Gilst Robert Clarke Anuj Goel Anders Hamsten John F Peden Udo Seedorf Ann-Christine Syvänen Giovanni Tognoni Edward G Lakatta Serena Sanna Paul Scheet David Schlessinger Angelo Scuteri Marcus Dörr Florian Ernst Stephan B Felix Georg Homuth Roberto Lorbeer Thorsten Reffelmann Rainer Rettig Uwe Völker Pilar Galan Ivo G Gut Serge Hercberg G Mark Lathrop Diana Zelenika Panos Deloukas Nicole Soranzo Frances M Williams Guangju Zhai Veikko Salomaa Markku Laakso Roberto Elosua Nita G Forouhi Henry Völzke Cuno S Uiterwaal Yvonne T van der Schouw Mattijs E Numans Giuseppe Matullo Gerjan Navis Göran Berglund Sheila A Bingham Jaspal S Kooner John M Connell Stefania Bandinelli Luigi Ferrucci Hugh Watkins Tim D Spector Jaakko Tuomilehto David Altshuler David P Strachan Maris Laan Pierre Meneton Nicholas J Wareham Manuela Uda Marjo-Riitta Jarvelin Vincent Mooser Olle Melander Ruth J F Loos Paul Elliott Gonçalo R Abecasis Mark Caulfield Patricia B Munroe

Nat Genet 2009 Jun 10;41(6):666-76. Epub 2009 May 10.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://csg.sph.umich.edu/boehnke/pdf/ng43-1005.pdf
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http://dx.doi.org/10.1038/ng.361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891673PMC
June 2009

Sequence variant on 8q24 confers susceptibility to urinary bladder cancer.

Nat Genet 2008 Nov 14;40(11):1307-12. Epub 2008 Sep 14.

Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ng.229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539560PMC
November 2008

DNA repair polymorphisms modify bladder cancer risk: a multi-factor analytic strategy.

Hum Hered 2008 26;65(2):105-18. Epub 2007 Sep 26.

Department of Community and Family Medicine, Section of Biostatistics and Epidemiology, Dartmouth Medical School, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1159/000108942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857629PMC
December 2007

Expression of DNA repair and metabolic genes in response to a flavonoid-rich diet.

Br J Nutr 2007 Sep 20;98(3):525-33. Epub 2007 Apr 20.

Institute for Scientific Interchange Foundation, Section of Life Sciences, viale Settimio Severo 65, Torino, Italy.

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http://dx.doi.org/10.1017/S0007114507725151DOI Listing
September 2007

Intake of fruits and vegetables and polymorphisms in DNA repair genes in bladder cancer.

Mutagenesis 2007 Jul 21;22(4):281-5. Epub 2007 May 21.

Unità di Epidemiologia dei Tumori, Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino and CPO-Piemonte, Torino, Italy.

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http://dx.doi.org/10.1093/mutage/gem014DOI Listing
July 2007

Polymorphisms/haplotypes in DNA repair genes and smoking: a bladder cancer case-control study.

Cancer Epidemiol Biomarkers Prev 2005 Nov;14(11 Pt 1):2569-78

Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, Norfolk Place, London W2 1PG, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-05-0189DOI Listing
November 2005

Estrogen receptor-alpha polymorphisms and angiographic outcome after coronary artery stenting.

Arterioscler Thromb Vasc Biol 2003 Dec 16;23(12):2223-8. Epub 2003 Oct 16.

Division of Cardiology, Universita del Piemonte Orientale, Ospedale Maggiore della Carita, Novara, Italy.

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http://dx.doi.org/10.1161/01.ATV.0000101181.81022.BFDOI Listing
December 2003

Effect of angiotensin-converting enzyme inhibition on restenosis after coronary stenting.

Am J Cardiol 2003 Jan;91(2):154-8

Division of Cardiology, Universitá del Piemonte Orientale, Ospedale Maggiore della Caritá, Novara, Italy.

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http://dx.doi.org/10.1016/s0002-9149(02)03101-6DOI Listing
January 2003