Publications by authors named "Simone P Niclou"

87 Publications

Glioblastoma Organoids: Pre-Clinical Applications and Challenges in the Context of Immunotherapy.

Front Oncol 2020 8;10:604121. Epub 2020 Dec 8.

NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.

View Article and Find Full Text PDF
December 2020

Temozolomide-Induced RNA Interactome Uncovers Novel LncRNA Regulatory Loops in Glioblastoma.

Cancers (Basel) 2020 Sep 10;12(9). Epub 2020 Sep 10.

NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg L-1526, Luxembourg.

View Article and Find Full Text PDF
September 2020

Is there a prominent role for MR spectroscopy in the clinical management of brain tumors?

Neuro Oncol 2020 07;22(7):903-904

NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Strassen, Luxembourg.

View Article and Find Full Text PDF
July 2020

Dual blockade of STAT3 and EGFR: a key to unlock drug resistance in glioblastoma?

Neuro Oncol 2020 04;22(4):440-441

NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg.

View Article and Find Full Text PDF
April 2020

Revealing and Harnessing Tumour-Associated Microglia/Macrophage Heterogeneity in Glioblastoma.

Int J Mol Sci 2020 Jan 21;21(3). Epub 2020 Jan 21.

Neuro-Immunology Group, Department of Oncology, Luxembourg Institute of Health, L-1526 Luxembourg, Luxembourg.

View Article and Find Full Text PDF
January 2020

Longitudinal molecular trajectories of diffuse glioma in adults.

Nature 2019 12 20;576(7785):112-120. Epub 2019 Nov 20.

The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.

View Article and Find Full Text PDF
December 2019

The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment.

Cells 2019 06 18;8(6). Epub 2019 Jun 18.

Immuno-Pharmacology and Interactomics, Department of Infection and Immunity, Luxembourg Institute of Health (LIH), L-1526 Luxembourg, Luxembourg.

View Article and Find Full Text PDF
June 2019

Irradiation to Improve the Response to Immunotherapeutic Agents in Glioblastomas.

Adv Radiat Oncol 2019 Apr-Jun;4(2):268-282. Epub 2018 Nov 20.

Department of Radiation Oncology, Centre François Baclesse, Esch-sur-Alzette, Luxembourg.

View Article and Find Full Text PDF
November 2018

Transcriptional and epigenetic mechanisms underlying astrocyte identity.

Prog Neurobiol 2019 03 29;174:36-52. Epub 2018 Dec 29.

NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-Belval, Luxembourg. Electronic address:

View Article and Find Full Text PDF
March 2019

RNAi/CRISPR Screens: from a Pool to a Valid Hit.

Trends Biotechnol 2019 01 31;37(1):38-55. Epub 2018 Aug 31.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg; Co-senior authors. Electronic address:

View Article and Find Full Text PDF
January 2019

Revival of the VEGF ligand family?

Authors:
Simone P Niclou

Neuro Oncol 2018 10;20(11):1421-1422

NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg.

View Article and Find Full Text PDF
October 2018

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors.

EMBO Mol Med 2018 09;10(9)

Molecular Signal Transduction Laboratories, Institute for Microscopic Anatomy and Neurobiology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn), University Medical Center of the Johannes Gutenberg University, Mainz, Germany

View Article and Find Full Text PDF
September 2018

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.

Br J Cancer 2017 Sep 10;117(6):813-825. Epub 2017 Aug 10.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, L-1526 Luxembourg City, Luxembourg.

View Article and Find Full Text PDF
September 2017

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

Int J Oncol 2017 Aug 21;51(2):702-714. Epub 2017 Jun 21.

Molecular Neuro-Oncology, Hertie Institute for Clinical Brain Research and Center Neurology, University of Tübingen, D-72076 Tübingen, Germany.

View Article and Find Full Text PDF
August 2017

Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma.

J Cereb Blood Flow Metab 2018 10 19;38(10):1741-1753. Epub 2017 Jun 19.

7 Norlux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.

View Article and Find Full Text PDF
October 2018

Harnessing LRIG1-mediated inhibition of receptor tyrosine kinases for cancer therapy.

Biochim Biophys Acta Rev Cancer 2017 Aug 1;1868(1):109-116. Epub 2017 Mar 1.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg; K.G. Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, 5020 Bergen, Norway. Electronic address:

View Article and Find Full Text PDF
August 2017