Simone P Niclou

Simone P Niclou

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Simone P Niclou

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Dual blockade of STAT3 and EGFR, a key to unlock drug resistance in Glioblastoma?

Neuro Oncol 2020 Feb 14. Epub 2020 Feb 14.

NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.

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http://dx.doi.org/10.1093/neuonc/noaa039DOI Listing
February 2020

Revealing and Harnessing Tumour-Associated Microglia/Macrophage Heterogeneity in Glioblastoma.

Int J Mol Sci 2020 Jan 21;21(3). Epub 2020 Jan 21.

Neuro-Immunology Group, Department of Oncology, Luxembourg Institute of Health, L-1526 Luxembourg, Luxembourg.

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http://dx.doi.org/10.3390/ijms21030689DOI Listing
January 2020

Longitudinal molecular trajectories of diffuse glioma in adults.

Nature 2019 12 20;576(7785):112-120. Epub 2019 Nov 20.

The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.

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http://dx.doi.org/10.1038/s41586-019-1775-1DOI Listing
December 2019

The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment.

Cells 2019 06 18;8(6). Epub 2019 Jun 18.

Immuno-Pharmacology and Interactomics, Department of Infection and Immunity, Luxembourg Institute of Health (LIH), L-1526 Luxembourg, Luxembourg.

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http://dx.doi.org/10.3390/cells8060613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627231PMC
June 2019

Transcriptional and epigenetic mechanisms underlying astrocyte identity.

Prog Neurobiol 2019 03 29;174:36-52. Epub 2018 Dec 29.

NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-Belval, Luxembourg. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2018.12.007DOI Listing
March 2019

RNAi/CRISPR Screens: from a Pool to a Valid Hit.

Trends Biotechnol 2019 01 31;37(1):38-55. Epub 2018 Aug 31.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg; Co-senior authors. Electronic address:

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http://dx.doi.org/10.1016/j.tibtech.2018.08.002DOI Listing
January 2019

Irradiation to Improve the Response to Immunotherapeutic Agents in Glioblastomas.

Adv Radiat Oncol 2019 Apr-Jun;4(2):268-282. Epub 2018 Nov 20.

Department of Radiation Oncology, Centre François Baclesse, Esch-sur-Alzette, Luxembourg.

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https://linkinghub.elsevier.com/retrieve/pii/S24521094183023
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http://dx.doi.org/10.1016/j.adro.2018.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460102PMC
November 2018

Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma.

J Cereb Blood Flow Metab 2018 10 19;38(10):1741-1753. Epub 2017 Jun 19.

7 Norlux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.

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http://dx.doi.org/10.1177/0271678X17714656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168744PMC
October 2018

Revival of the VEGF ligand family?

Authors:
Simone P Niclou

Neuro Oncol 2018 10;20(11):1421-1422

NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg.

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http://dx.doi.org/10.1093/neuonc/noy127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178279PMC
October 2018

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors.

EMBO Mol Med 2018 09;10(9)

Molecular Signal Transduction Laboratories, Institute for Microscopic Anatomy and Neurobiology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn), University Medical Center of the Johannes Gutenberg University, Mainz, Germany

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http://dx.doi.org/10.15252/emmm.201708420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127886PMC
September 2018

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.

Br J Cancer 2017 Sep 10;117(6):813-825. Epub 2017 Aug 10.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, L-1526 Luxembourg City, Luxembourg.

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http://dx.doi.org/10.1038/bjc.2017.263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590001PMC
September 2017

Harnessing LRIG1-mediated inhibition of receptor tyrosine kinases for cancer therapy.

Biochim Biophys Acta Rev Cancer 2017 Aug 1;1868(1):109-116. Epub 2017 Mar 1.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg; K.G. Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, 5020 Bergen, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2017.02.007DOI Listing
August 2017

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

Int J Oncol 2017 Aug 21;51(2):702-714. Epub 2017 Jun 21.

Molecular Neuro-Oncology, Hertie Institute for Clinical Brain Research and Center Neurology, University of Tübingen, D-72076 Tübingen, Germany.

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http://dx.doi.org/10.3892/ijo.2017.4051DOI Listing
August 2017

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

Neuro Oncol 2016 12 10;18(12):1644-1655. Epub 2016 Jun 10.

Department of Biomedicine, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., T.T., K.V., J.A.H., J.V.J., R.J., H.S.S., L.L., T.D., P.Ø.E., R.B., H.M.); KG Jebsen Brain Tumor Research Center, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., K.V., J.A.H., J.V.J., T.D., P. Ø.E., S.P.N., R.B., H.M.); Department of Clinical Science, University of Bergen, Norway (S.K.); Department of Oncology, Haukeland University Hospital, Bergen, Norway (S.K.); Norlux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg (O.K., S.F., S.P.N., R.B.); Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK (A.S.); Department of Clinical Pharmacy, Institute of Pharmacy, Ernst-Moritz-Arndt-University, Greifswald, Germany (S.F., C.A.R.); Department of Neurooncology, University Hospital Heidelberg, Germany (G.S., F.W.); Institute of Scientific Instruments, ASCR, Brno, Czech Republic (R.J.); Edinger-Intsitute, Goethe-University Medical School, Frankfurt am Main, Germany (P.N.H.); Department of Pathology, Haukeland University Hospital, Bergen, Norway (J.A.H., H.M.); Department of Clinical Neurosciences, University of Cambridge, UK (S.G.P., C.W.); Statistics and Computational Biology Laboratory, University of Cambridge, UK (I.S.); Neuro Clinic, Haukeland University Hospital, Bergen, Norway; Department of Experimental Neurology, Charité - Universitätsmedizin Berlin, Germany (P.E.); Department of Systems Medicine, University of Rome «Tor Vergata», Rome, Italy (G.G.); INSERM U1029 - University of Bordeaux, Allée Geoffroy St. Hilaire, Pessac, France (T.D.); Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway (M.L.-J., P. Ø.E.).

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http://dx.doi.org/10.1093/neuonc/now113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791772PMC
December 2016

Combined VEGFR and CTLA-4 blockade increases the antigen-presenting function of intratumoral DCs and reduces the suppressive capacity of intratumoral MDSCs.

Am J Cancer Res 2016 1;6(11):2514-2531. Epub 2016 Nov 1.

Laboratory of Molecular and Cellular Therapy, Vrije Universiteit Brussel Laarbeeklaan 103E, 1090, Brussels, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126270PMC
November 2016

Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma.

PLoS One 2015 1;10(5):e0123544. Epub 2015 May 1.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health (L.I.H.), Luxembourg, Luxembourg; KG Jebsen Brain Tumour Research Center, Department of Biomedicine, University of Bergen, Bergen, Norway.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123544PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416792PMC
February 2016

Targeted Proteomics to Assess the Response to Anti-Angiogenic Treatment in Human Glioblastoma (GBM).

Mol Cell Proteomics 2016 Feb 4;15(2):481-92. Epub 2015 Aug 4.

From the ‡NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg; ¶KG Jebsen Brain Tumour Research Center, Department of Biomedicine, University of Bergen, Bergen, Norway

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http://dx.doi.org/10.1074/mcp.M115.052423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739668PMC
February 2016

Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

FASEB J 2015 Nov 28;29(11):4695-712. Epub 2015 Jul 28.

*Department of Biomedicine, Biomaterials, Department of Clinical Dentistry, and K. G. Jebsen Brain Tumour Research Center, University of Bergen, Bergen, Norway; Department of Pathology and Department of Clinical Medicine, Haukeland University Hospital, Bergen, Norway; and NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health (LIH), Luxembourg, Luxembourg.

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http://dx.doi.org/10.1096/fj.14-268615DOI Listing
November 2015

Gauging heterogeneity in primary versus recurrent glioblastoma.

Authors:
Simone P Niclou

Neuro Oncol 2015 Jul 12;17(7):907-9. Epub 2015 May 12.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg and K.G. Jebsen Brain Tumor Research Center, Department of Biomedicine, University of Bergen, Norway.

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http://dx.doi.org/10.1093/neuonc/nov078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762011PMC
July 2015

Axitinib increases the infiltration of immune cells and reduces the suppressive capacity of monocytic MDSCs in an intracranial mouse melanoma model.

Oncoimmunology 2015 Apr 22;4(4):e998107. Epub 2015 Jan 22.

Laboratory of Molecular and Cellular Therapy; Department of Immunology-Physiology; Vrije Universiteit Brussel , Brussels, Belgium.

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http://dx.doi.org/10.1080/2162402X.2014.998107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485747PMC
April 2015

Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma.

Cell Commun Signal 2015 Mar 31;13:23. Epub 2015 Mar 31.

Department of Oncology, NorLux Neuro-Oncology Laboratory, Luxembourg Institute of Health (LIH), Luxembourg, Luxembourg.

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http://dx.doi.org/10.1186/s12964-015-0098-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391485PMC
March 2015

Whole genomes redefine the mutational landscape of pancreatic cancer.

Nature 2015 Feb;518(7540):495-501

1] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia [2] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

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http://dx.doi.org/10.1038/nature14169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523082PMC
February 2015

Databases for lncRNAs: a comparative evaluation of emerging tools.

RNA 2014 Nov;20(11):1655-65

NorLux Neuro-Oncology Laboratory, Department of Oncology, Centre de Recherche Public de la Santé (CRP-Santé), Luxembourg L-1526, Luxembourg

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http://dx.doi.org/10.1261/rna.044040.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201818PMC
November 2014

A novel multilayer immunoisolating encapsulation system overcoming protrusion of cells.

Sci Rep 2014 Oct 31;4:6856. Epub 2014 Oct 31.

Department of Pathology and Medical Biology; Immunoendocrinology, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1038/srep06856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215319PMC
October 2014

Factors influencing the mechanical stability of alginate beads applicable for immunoisolation of mammalian cells.

J Mech Behav Biomed Mater 2014 Sep 2;37:196-208. Epub 2014 Jun 2.

Department of Pathology and Medical Biology; Immunoendocrinology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S17516161140015
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http://dx.doi.org/10.1016/j.jmbbm.2014.05.020DOI Listing
September 2014

Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies.

Adv Drug Deliv Rev 2014 Sep 28;76:98-115. Epub 2014 Jul 28.

Translational Cancer Research, Department of Biomedicine, University of Bergen, Norway; Molecular Imaging Center, Department of Biomedicine, University of Bergen, Norway; The Kristian Gerhard Jebsen Brain Tumour Research Center, Department of Biomedicine, University of Bergen, Norway.

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http://dx.doi.org/10.1016/j.addr.2014.07.010DOI Listing
September 2014

PeptideManager: a peptide selection tool for targeted proteomic studies involving mixed samples from different species.

Front Genet 2014 2;5:305. Epub 2014 Sep 2.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Centre de Recherche Public de la Santé Luxembourg, Luxembourg.

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http://dx.doi.org/10.3389/fgene.2014.00305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151198PMC
September 2014

Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?

Biochim Biophys Acta 2014 Aug 18;1846(1):66-74. Epub 2014 Apr 18.

Radboud University Medical Centre, Department of Pathology, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2014.04.004DOI Listing
August 2014

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture.

Proteome Sci 2014 11;12:39. Epub 2014 Jul 11.

OncoProteomics Laboratory, Department of Medical Oncology, VUmc-Cancer Center Amsterdam, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.

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http://dx.doi.org/10.1186/1477-5956-12-39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114130PMC
July 2014

Bevacizumab treatment for human glioblastoma. Can it induce cognitive impairment?

Neuro Oncol 2014 May;16(5):754-6

Department of Biomedicine, University of Bergen, Norway (P.F., N.O., H.E.,P.Ø.S., R.B); Centre de Recherche Public de la Santé, Luxembourg (D.S., O.K., S.P.N.).

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http://dx.doi.org/10.1093/neuonc/nou013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984560PMC
May 2014

Drug and cell encapsulation: alternative delivery options for the treatment of malignant brain tumors.

Adv Drug Deliv Rev 2014 Apr 31;67-68:142-53. Epub 2014 Jan 31.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Centre de Recherche Public de la Santé (CRP-Santé), 84, Val Fleuri, L-1586 Luxembourg, Luxembourg. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2014.01.010DOI Listing
April 2014

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia.

Proc Natl Acad Sci U S A 2013 Oct 7;110(43):17450-5. Epub 2013 Oct 7.

Laboratory of Experimental Hemato-Oncology, Department of Oncology, and Laboratory of Immunogenetics and Allergology, Public Research Center for Health, L-1526 Luxembourg City, Luxembourg.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1304790110
Publisher Site
http://dx.doi.org/10.1073/pnas.1304790110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808626PMC
October 2013

The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status.

Neuro Oncol 2013 Sep 30;15(9):1200-11. Epub 2013 May 30.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Centre de Recherche Public de la Santé, Luxembourg, Luxembourg, Sweden.

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http://dx.doi.org/10.1093/neuonc/not054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748912PMC
September 2013

In vivo animal models for studying brain metastasis: value and limitations.

Clin Exp Metastasis 2013 Jun 16;30(5):695-710. Epub 2013 Jan 16.

NorLux Neuro-Oncology Laboratory, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5019, Bergen, Norway.

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http://link.springer.com/10.1007/s10585-013-9566-9
Publisher Site
http://dx.doi.org/10.1007/s10585-013-9566-9DOI Listing
June 2013

Combined effect of tissue stabilization and protein extraction methods on phosphoprotein analysis.

Biopreserv Biobank 2013 Jun 29;11(3):161-5. Epub 2013 May 29.

1 Integrated BioBank of Luxembourg (IBBL) , Luxembourg .

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http://dx.doi.org/10.1089/bio.2013.0008DOI Listing
June 2013

Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells.

Brain 2013 May 4;136(Pt 5):1462-75. Epub 2013 Mar 4.

NorLux Neuro-Oncology Laboratory, Centre de Recherche Public de la Santé (CRP-Santé), Department of Oncology NorLux Neuro-Oncology Laboratory 84, Val Fleuri, L- 1526 Luxembourg.

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http://dx.doi.org/10.1093/brain/awt025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634193PMC
May 2013

In vivo models of primary brain tumors: pitfalls and perspectives.

Neuro Oncol 2012 Aug 7;14(8):979-93. Epub 2012 Jun 7.

NorLux, Neuro-Oncology Laboratory, Department of Biomedicine, University of Bergen, Bergen, Norway.

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/nos135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408261PMC
August 2012

Novel ways to target brain tumour metabolism.

Expert Opin Ther Targets 2011 Oct 2;15(10):1227-39. Epub 2011 Jun 2.

Centre de Recherche Public de la Santé (CRP-Santé), Oncology Department , NorLux Neuro-Oncology Laboratory, Luxembourg.

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http://dx.doi.org/10.1517/14728222.2011.588211DOI Listing
October 2011

Critical appraisal of the side population assay in stem cell and cancer stem cell research.

Cell Stem Cell 2011 Feb;8(2):136-47

NorLux Neuro-Oncology Laboratory, Oncology Department, Centre de Recherche Public de la Santé, 84 Val Fleuri, Luxembourg.

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http://dx.doi.org/10.1016/j.stem.2011.01.007DOI Listing
February 2011

Glioma proteomics: status and perspectives.

J Proteomics 2010 Sep 20;73(10):1823-38. Epub 2010 Mar 20.

Norlux Neuro-Oncology Laboratory, Department of Oncology, Centre de Recherche Public de la Santé (CRP-Santé), Luxembourg, Luxembourg.

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http://dx.doi.org/10.1016/j.jprot.2010.03.007DOI Listing
September 2010

Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system.

BMC Neurosci 2010 Feb 18;11:20. Epub 2010 Feb 18.

Department of Neuroregeneration, Netherlands Institute for Neuroscience, an institute of the Royal Academy of Arts and Sciences, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1186/1471-2202-11-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841193PMC
February 2010

iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype.

Mol Cell Proteomics 2009 Nov 12;8(11):2595-612. Epub 2009 Aug 12.

Norlux Neuro-Oncology Laboratory, Department of Oncology, Centre de Recherche Public Santé (CRP-Santé), 84 Val Fleuri, L-1526 Luxembourg, Luxembourg.

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http://dx.doi.org/10.1074/mcp.M900124-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773724PMC
November 2009

Cancer stem cells and angiogenesis.

Semin Cancer Biol 2009 Oct 7;19(5):279-84. Epub 2009 Oct 7.

NorLux Neuro-Oncology, Department of Biomedicine, University of Bergen, N-5009, Bergen, Norway.

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http://dx.doi.org/10.1016/j.semcancer.2009.09.001DOI Listing
October 2009

Anti-VEGF therapies for malignant glioma: treatment effects and escape mechanisms.

Expert Opin Ther Targets 2009 Apr;13(4):455-68

Department of Biomedicine, University of Bergen, NorLux Neuro-Oncology, Bergen, Norway.

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http://dx.doi.org/10.1517/14728220902806444DOI Listing
April 2009

Proteomics strategies for target identification and biomarker discovery in cancer.

Front Biosci (Landmark Ed) 2009 Jan 1;14:3292-303. Epub 2009 Jan 1.

Norlux Neuro-Oncology Laboratory, CRP-Sante, 84, Val Fleuri, L-1526 Luxembourg, Luxembourg. www.norlux.lu

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http://dx.doi.org/10.2741/3452DOI Listing
January 2009

Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization.

Diabetes 2008 Sep 2;57(9):2393-401. Epub 2008 Jun 2.

Division of Clinical Immunology, Department of Oncology, Radiology and Clinical Immunology, Uppsala University, Uppsala, Sweden.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db07-09
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http://dx.doi.org/10.2337/db07-0981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518490PMC
September 2008

The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease.

Mol Cell Neurosci 2006 May-Jun;32(1-2):102-17. Epub 2006 May 3.

Graduate School for Neurosciences Amsterdam, Netherlands Institute for Brain Research, Meibergdreef 33, 1105 AZ Amsterdam, Netherlands.

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http://dx.doi.org/10.1016/j.mcn.2006.03.002DOI Listing
September 2006

Cell therapies for glioblastoma.

Expert Opin Biol Ther 2006 Aug;6(8):739-49

National Department of Neurosurgery, Hospital Center Luxembourg, 4 Rue Barblé, L-1210, Luxembourg.

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http://dx.doi.org/10.1517/14712598.6.8.739DOI Listing
August 2006

Chemorepellent axon guidance molecules in spinal cord injury.

J Neurotrauma 2006 Mar-Apr;23(3-4):409-21

Netherlands Institute for Brain Research, Laboratory for Neuroregeneration, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1089/neu.2006.23.409DOI Listing
June 2006

Lentiviral-mediated transfer of CNTF to schwann cells within reconstructed peripheral nerve grafts enhances adult retinal ganglion cell survival and axonal regeneration.

Mol Ther 2005 Jun;11(6):906-15

School of Anatomy and Human Biology, Western Australian Institute for Medical Research, UWA Centre for Medical Research, Perth, Australia.

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http://dx.doi.org/10.1016/j.ymthe.2005.01.016DOI Listing
June 2005

Prothrombin overexpressed in post-natal neurones requires blood factors for activation in the mouse brain.

J Neurochem 2004 Mar;88(6):1380-8

Friedrich-Miescher Institute for Biomedical Research, Basel, Switzerland.

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http://dx.doi.org/10.1046/j.1471-4159.2003.02268.xDOI Listing
March 2004

Meningeal cell-derived semaphorin 3A inhibits neurite outgrowth.

Mol Cell Neurosci 2003 Dec;24(4):902-12

Graduate School of Neurosciences Amsterdam, Netherlands Institute for Brain Research, Meibergdreef 33, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/s1044-7431(03)00243-4DOI Listing
December 2003

The astrocyte/meningeal cell interface is a barrier to neurite outgrowth which can be overcome by manipulation of inhibitory molecules or axonal signalling pathways.

Mol Cell Neurosci 2003 Dec;24(4):913-25

Department of Physiology and Cambridge Centre for Brain Repair, University of Cambridge, Cambridge CB2 3EG, England, UK.

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http://dx.doi.org/10.1016/j.mcn.2003.09.004DOI Listing
December 2003