Publications by authors named "Simona Rizea Savu"

17 Publications

  • Page 1 of 1

Single Dose Study Assessing the Pharmacokinetic and Metabolic Profile of Alverine Citrate in Healthy Volunteers.

Authors:
Simona Rizea-Savu Simona Nicoleta Duna Roxana Colette Sandulovici

Front Pharmacol 2020 20;11:620451. Epub 2021 Jan 20.

Faculty of Pharmacy, Titu Maiorescu University, Bucharest, Romania.

View Article and Find Full Text PDF
January 2021

The Effect of Food on the Single-Dose Bioavailability and Tolerability of the Highest Marketed Strength of Duloxetine.

Authors:
Simona Rizea-Savu Simona Nicoleta Duna Adrian Ghita Adriana Iordachescu Marinela Chirila

Clin Pharmacol Drug Dev 2020 10 2;9(7):797-804. Epub 2019 Dec 2.

Medochemie Ltd, Limassol, Cyprus.

View Article and Find Full Text PDF
October 2020

12th GCC Closed Forum: critical reagents; oligonucleotides; CoA; method transfer; HRMS; flow cytometry; regulatory findings; stability and immunogenicity.

Authors:
Chad Briscoe Nicola Hughes Roger Hayes Rafiq Islam Patrick Bennett Bruce Stouffer Stephanie Cape Paul Rhyne Chris Beaver Jessica St Charles Vellalore Kakkanaiah Allan Xu Maria Cruz Caturla Franklin Spriggs Rabab Tayyem Colin Barry Anahita Keyhani Jennifer Zimmer Philippe Couerbe Mark Warren Ardeshir Khadang James Bourdage Kathie Lindley Dave Williams Curtis Sheldon Christina Satterwhite Jenifer Vija Mathilde Yu Iohann Boulay John Stamatopoulos Jenny Lin Sian Estdale Eric Thomas Andrew Dinan Robert MacNeill Yi Qun Xiao Luca Matassa Wei Garofolo Natasha Savoie George Hristopoulos Arron Xu Lawrence Goodwin Kayode Awaiye Hanna Ritzén Mohammed Bouhajib Chantal Di Marco Simona Rizea Savu Corey Nehls Edward Tabler Amanda Hays Shane Karnik Michael Brown Steve Lowes Ira DuBey Nadia Kulagina John Lindsay Clark Williard Hao Wang Michele Malone Edward Wells Xinping Fang Marc Moussallie

Bioanalysis 2019 Jun 19;11(12):1129-1138. Epub 2019 Jul 19.

WuXi Apptec, Plainsboro, NJ 08536, USA.

View Article and Find Full Text PDF
June 2019

Recommendations for classification of commercial LBA kits for biomarkers in drug development from the GCC for bioanalysis.

Authors:
Rafiq Islam Sumit Kar Hanna Ritzén Amanda Hays Rabab Tayyem Colin Barry Anahita Keyhani Jennifer Zimmer Maria Cruz Caturla Philippe Couerbe Mark Warren Ardeshir Khadang James Bourdage Kathie Lindley Dave Williams Nicola Hughes Curtis Sheldon Christina Satterwhite Jenifer Vija Mathilde Yu Iohann Boulay John Stamatopoulos Jenny Lin Stephanie Cape Sian Estdale Eric Thomas Andrew Dinan Robert MacNeill Yi Qun Xiao Wei Garofolo Natasha Savoie Michael Brown Paul Rhyne George Hristopoulos Arron Xu Lawrence Goodwin Franklin Spriggs Allan Xu Kayode Awaiye Roger Hayes Jessica St Charles Mohammed Bouhajib Chantal DiMarco Luigi DiMarco Simona Rizea Savu Patrick Bennett Vellalore Kakkanaiah Corey Nehls Bruce Stouffer Edward Tabler Chad Briscoe Shane Karnik Ira DuBey Nadia Kulagina John Lindsay Chris Beaver Clark Williard Hao Wang Hao Feng Michele Malone Edward Wells Xinping Fang Marc Moussallie

Bioanalysis 2019 Apr 17;11(7):645-653. Epub 2019 Apr 17.

WuXi Apptec, Plainsboro, NJ, USA.

View Article and Find Full Text PDF
April 2019

Single-Dose Pharmacokinetic Properties and Relative Bioavailability of Different Formulations of Posaconazole Oral Suspension in Healthy Volunteers.

Authors:
Lucija Vuletić Marina Herceg Kristina Ferderber Iva Tunjić Simona Rizea-Savu Simona Nicoleta Duna Biserka Cetina-Čižmek Jelena Filipović-Grčić

Clin Pharmacol Drug Dev 2019 08 10;8(6):827-836. Epub 2018 Dec 10.

University of Zagreb, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Technology, Zagreb, Croatia.

View Article and Find Full Text PDF
August 2019

The 10th GCC Closed Forum: rejected data, GCP in bioanalysis, extract stability, BAV, processed batch acceptance, matrix stability, critical reagents, ELN and data integrity and counteracting fraud.

Authors:
Stephanie Cape Rafiq Islam Corey Nehls John Allinson Afshin Safavi Patrick Bennett James Hulse Chris Beaver Masood Khan Shane Karnik Maria Cruz Caturla Steve Lowes Adriana Iordachescu Luigi Silvestro Rabab Tayyem Ron Shoup Stephanie Mowery Anahita Keyhani Andrea Wakefield Yinghe Li Jennifer Zimmer Javier Torres Philippe Couerbe Ardeshir Khadang James Bourdage Nicola Hughes Kayode Awaiye Brent Matthews Saadya Fatmi Rhonda Johnson Christina Satterwhite Mathilde Yu Jenny Lin Laura Cojocaru Michele Fiscella Eric Thomas Kai Kurylak John Kamerud Zhongping John Lin Wei Garofolo Natasha Savoie Mike Buonarati Nadine Boudreau Clark Williard Yansheng Liu Dominic Warrino Prashant Kale Neil Adcock Radha Shekar Edward O'Connor Hanna Ritzen Christina Sanchez Roger Hayes Mohammed Bouhajib Simona Rizea Savu Bruce Stouffer Edward Tabler Jing Tu Chad Briscoe Barry van der Strate Paul Rhyne Phyllis Conliffe Ira DuBey Jim Yamashita Daniel Tang Elizabeth Groeber Jenifer Vija Michele Malone Mohamed Osman

Bioanalysis 2017 Apr 24;9(7):505-516. Epub 2017 Mar 24.

WuXi Apptec, Plainsboro, NJ, USA.

View Article and Find Full Text PDF
April 2017

Evaluation of Clopidogrel Conjugation Metabolism: PK Studies in Man and Mice of Clopidogrel Acyl Glucuronide.

Authors:
Simona Nicoleta Savu Luigi Silvestro Mariana Surmeian Lina Remis Yuksel Rasit Simona Rizea Savu Constantin Mircioiu

Drug Metab Dispos 2016 09 11;44(9):1490-7. Epub 2016 Jul 11.

Department of Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila," Bucharest, Romania (S.N.S., C.M.); 3S-Pharmacological Consultation and Research GmbH, Harpstedt, Germany (S.N.S, L.S., S.R.S.); Pharma Serv International SRL, Bucharest, Romania (M.S.); Clinical Hospital of the Ministry of Health of the Moldavian Republic, Chisinau, The Moldavian Republic (L.R.); Pharmacology Department, National Institute for Chemical Pharmaceutical Research and Development (ICCF), Bucharest, Romania (Y.R.).

View Article and Find Full Text PDF
September 2016

An update on solid phase-supported liquid extraction.

Authors:
Luigi Silvestro Simona Rizea Savu

Bioanalysis 2015 17;7(17):2177-86. Epub 2015 Sep 17.

3S-Pharmacological Consultation & Research GmbH, Koenigsberger Strasse 1 27243 Harpstedt, Germany.

View Article and Find Full Text PDF
July 2016

Pharmacokinetic study for the establishment of bioequivalence of two inhalation treatments containing budesonide plus formoterol.

Authors:
Nikolaos Grekas Katerina Athanassiou Katerina Papataxiarchou Simona Rizea Savu Luigi Silvestro

J Pharm Pharmacol 2014 Dec 11;66(12):1677-85. Epub 2014 Aug 11.

ELPEN Pharmaceutical Co Inc., Pikermi, Greece.

View Article and Find Full Text PDF
December 2014

Confirmation of diosmetin 3-O-glucuronide as major metabolite of diosmin in humans, using micro-liquid-chromatography-mass spectrometry and ion mobility mass spectrometry.

Authors:
Luigi Silvestro Isabela Tarcomnicu Constanta Dulea Nageswara Rao B N Attili Valentin Ciuca Dan Peru Simona Rizea Savu

Anal Bioanal Chem 2013 Oct 16;405(25):8295-310. Epub 2013 Aug 16.

3S-Pharmacological Consultation and Research GmbH, Koenigsbergerstrasse 1, 27243, Harpstedt, Germany,

View Article and Find Full Text PDF
October 2013

Development of a sensitive method for simultaneous determination of fluticasone propionate and salmeterol in plasma samples by liquid chromatography-tandem mass spectrometry.

Authors:
Luigi Silvestro Simona Rizea Savu Simona Nicoleta Savu Ariana Tudoroniu Isabela Tarcomnicu

Biomed Chromatogr 2012 May;26(5):627-35

3S-Pharmacological Consultation and Research GmbH, Koenigsbergerstrasse 1, 27243 Harpstedt, Germany.

View Article and Find Full Text PDF
May 2012

Development and validation of an HPLC-MS/MS method to quantify clopidogrel acyl glucuronide, clopidogrel acid metabolite, and clopidogrel in plasma samples avoiding analyte back-conversion.

Authors:
Luigi Silvestro Mihaela Gheorghe Adriana Iordachescu Valentin Ciuca Ariana Tudoroniu Simona Rizea Savu Isabela Tarcomnicu

Anal Bioanal Chem 2011 Aug 9;401(3):1023-34. Epub 2011 Jun 9.

3S-Pharmacological Consultation & Research GmbH, Koenigsbergerstrasse 1, 27243 Harpstedt, Germany.

View Article and Find Full Text PDF
August 2011

Development and validation of an HPLC-MS/MS method to determine clopidogrel in human plasma. Use of incurred samples to test back-conversion.

Authors:
Luigi Silvestro Mihaela Cristina Gheorghe Isabela Tarcomnicu Silviu Savu Simona Rizea Savu Adriana Iordachescu Constanta Dulea

J Chromatogr B Analyt Technol Biomed Life Sci 2010 Nov 1;878(30):3134-42. Epub 2010 Oct 1.

3S-Pharmacological Consultation & Research GmbH, Koenigsbergerstrasse 1, 27243 Harpstedt, Germany.

View Article and Find Full Text PDF
November 2010

High-throughput HPLC-MS/MS method to determine ibandronate in human plasma for pharmacokinetic applications.

Authors:
Isabela Tarcomnicu Mihaela Cristina Gheorghe Luigi Silvestro Simona Rizea Savu Irina Boaru Ariana Tudoroniu

J Chromatogr B Analyt Technol Biomed Life Sci 2009 Oct 12;877(27):3159-68. Epub 2009 Aug 12.

Pharma Serv Int'l SRL, 52 Sabinelor Str., 5th District, 050853 Bucharest, Romania.

View Article and Find Full Text PDF
October 2009

Development and application of a high-performance liquid chromatography-mass spectrometry method to determine alendronate in human urine.

Authors:
Isabela Tarcomnicu Luigi Silvestro Simona Rizea Savu Adriana Gherase Constanta Dulea

J Chromatogr A 2007 Aug 19;1160(1-2):21-33. Epub 2007 Apr 19.

Pharma Serv International SRL, 52 Sabinelor Street, 5th District, 050853 Bucharest, Romania.

View Article and Find Full Text PDF
August 2007

Adhesion inhibition "in vitro" by heparin derivatives correlates with their activity on angiogenesis in mice.

Authors:
Simona Rizea Savu L Silvestro

J Cell Mol Med 2003 Apr-Jun;7(2):187-91

National Institute for Pharmaceutical Chemistry, 112 Vitan Rd., Bucharest, Romania.

View Article and Find Full Text PDF
March 2004

Intra-plaque production of platelet-activating factor correlates with neoangiogenesis in human carotid atherosclerotic lesions.

Authors:
Enrico Lupia Angela Pucci Paolo Peasso Maurizio Merlo Paolo Baron Cristina Zanini Lorenzo Del Sorbo Simona Rizea-Savu Luigi Silvestro Marco Forni Giorgio Emanuelli Giovanni Camussi Giuseppe Montrucchio

Int J Mol Med 2003 Sep;12(3):327-34

Dipartimento di Fisiopatologia Clinica, Universitá degli Studi di Torino, Torino, Italy.

View Article and Find Full Text PDF
September 2003