Simona Coco

Simona Coco

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Simona Coco

Simona Coco

Publications by authors named "Simona Coco"

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Microvascular obstruction extent predicts major adverse cardiovascular events in patients with acute myocardial infarction and preserved ejection fraction.

Eur Radiol 2019 May 14;29(5):2369-2377. Epub 2018 Dec 14.

Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome "Sapienza", Viale Regina Elena 324, 00161, Rome, Italy.

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http://dx.doi.org/10.1007/s00330-018-5895-zDOI Listing
May 2019

The evolving role of pemetrexed disodium for the treatment of non-small cell lung cancer.

Expert Opin Pharmacother 2018 Dec 24;19(17):1969-1976. Epub 2018 Oct 24.

b Medical Oncology , Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico , Milan , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14656566.2018.1
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http://dx.doi.org/10.1080/14656566.2018.1536746DOI Listing
December 2018

Afatinib and Erlotinib in the treatment of squamous-cell lung cancer.

Expert Opin Pharmacother 2018 12 3;19(18):2055-2062. Epub 2018 Nov 3.

c Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Medical Oncology , Milan , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14656566.2018.1
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http://dx.doi.org/10.1080/14656566.2018.1540591DOI Listing
December 2018

Understanding the checkpoint blockade in lung cancer immunotherapy.

Drug Discov Today 2017 08 7;22(8):1266-1273. Epub 2017 Jun 7.

Lung Cancer Unit, Ospedale Policlinico San Martino, Istituto di Ricovero e Cura a Carattere Scientifico per l'Oncologia, Largo R. Benzi, 10-16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.drudis.2017.05.016DOI Listing
August 2017

Prognostic and Therapeutic Implications of MicroRNA in Malignant Pleural Mesothelioma.

Microrna 2016 ;5(1):12-18

Lung Cancer Unit, IRCCS AOU San Martino-IST, L. go R. Benzi 10, 16132 Genova, Italy.

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June 2017

Fibroblast Growth Factor Receptor (FGFR): A New Target for Non-small Cell Lung Cancer Therapy.

Anticancer Agents Med Chem 2016 ;16(9):1142-54

UOS Tumori Polmonari, IRCCS AOU San Martino IST- Istituto Nazionale per la Ricerca sul Cancro, Largo Rosanna Benzi n°10, 16132 Genova, Italy.

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June 2017

Exosomes: a new horizon in lung cancer.

Drug Discov Today 2017 06 10;22(6):927-936. Epub 2017 Mar 10.

UOS Tumori Polmonari, IRCCS AOU San Martino IST-Istituto Nazionale per la Ricerca sul Cancro, Largo R. Benzi, 10-16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.drudis.2017.03.004DOI Listing
June 2017

Investigational drugs targeting fibroblast growth factor receptor in the treatment of non-small cell lung cancer.

Expert Opin Investig Drugs 2017 May 13;26(5):551-561. Epub 2017 Apr 13.

a UOS Tumori Polmonari , IRCCS AOU San Martino IST- Istituto Nazionale per la Ricerca sul Cancro , Genova , Italy.

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http://dx.doi.org/10.1080/13543784.2017.1316714DOI Listing
May 2017

New systemic strategies for overcoming resistance to targeted therapies in non-small cell lung cancer.

Expert Opin Pharmacother 2017 Jan 23;18(1):19-33. Epub 2016 Nov 23.

a Lung Cancer Unit , San Martino Hospital - National Institute for Cancer Research , Genova , Italy.

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http://dx.doi.org/10.1080/14656566.2016.1261109DOI Listing
January 2017

Whole exome sequencing of independent lung adenocarcinoma, lung squamous cell carcinoma, and malignant peritoneal mesothelioma: A case report.

Medicine (Baltimore) 2016 Nov;95(48):e5447

aLung Cancer Unit, IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genova bCentre for Translational Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute, Milan cDepartment of Internal Medicine and Medical Specialties (DIMI), Università di Genova IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genova dDepartment of Pathology, IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genova eLaboratory of Tumor Epigenetics, IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro and Department of Health Sciences, Università di Genova, Genova, Italy.

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http://dx.doi.org/10.1097/MD.0000000000005447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134773PMC
November 2016

Belagenpumatucel-L for the treatment of non-small cell lung cancer.

Expert Opin Biol Ther 2015 27;15(9):1371-9. Epub 2015 Jul 27.

IRCCS AOU San Martino IST- Istituto Nazionale per la Ricerca sul Cancro, UOS Tumori Polmonari , Largo Rosanna Benzi n° 10, 16132 Genova , Italy +39 0105600665; +39 0105600795;

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http://dx.doi.org/10.1517/14712598.2015.1073709DOI Listing
March 2016

Genome instability model of metastatic neuroblastoma tumorigenesis by a dictionary learning algorithm.

BMC Med Genomics 2015 Sep 10;8:57. Epub 2015 Sep 10.

Neuroblastoma Laboratory, Onco/Hematology Laboratory, Department of Woman and Child Health, University of Padua, Pediatric Research Institute, Fondazione Città della Speranza, Padua, Corso Stati Uniti, 4, 35127, Padua, Italy.

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http://dx.doi.org/10.1186/s12920-015-0132-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566396PMC
September 2015

Uncommon EGFR Exon 19 Mutations Confer Gefitinib Resistance in Advanced Lung Adenocarcinoma.

J Thorac Oncol 2015 Jun;10(6):e50-2

Lung Cancer Unit, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy Biopolymers and Proteomics Unit, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy Lung Cancer Unit, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy Molecular Oncology and Angiogenesis Unit, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy Lung Cancer Unit, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy Dipartimento di Medicina Interna e Specialità Mediche (DIMI), IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy, UOC Clinica di Oncologia Medica, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro Genova, Italy Lung Cancer Unit, IRCCS AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000538DOI Listing
June 2015

Prognostic and predictive relevance of circulating tumor cells in patients with non-small-cell lung cancer.

Drug Discov Today 2014 Oct 10;19(10):1671-6. Epub 2014 Jun 10.

Lung Cancer Unit, IRCCS AOU San Martino IST, Largo R. Benzi, 10-16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.drudis.2014.06.001DOI Listing
October 2014

Efficacy of motesanib diphosphate in non-small-cell lung cancer.

Expert Opin Pharmacother 2014 Aug;15(12):1771-80

IRCCS AOU San Martino IST - Istituto Nazionale per la Ricerca sul Cancro, UOS Tumori Polmonari , Largo Rosanna Benzi No 10, 16132 Genova , Italy +39 0105600665 ; +39 0105600795 ;

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http://dx.doi.org/10.1517/14656566.2014.938639DOI Listing
August 2014

Ipilimumab in non-small cell lung cancer and small-cell lung cancer: new knowledge on a new therapeutic strategy.

Expert Opin Biol Ther 2014 Jul 5;14(7):1007-17. Epub 2014 Apr 5.

UOS Tumori Polmonari, IRCCS San Martino - IST Istituto Nazionale per la Ricerca sul Cancro , L.go Benzi 10, Genova , Italy

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http://www.tandfonline.com/doi/full/10.1517/14712598.2014.90
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http://dx.doi.org/10.1517/14712598.2014.907786DOI Listing
July 2014

Afatinib for the treatment of advanced non-small-cell lung cancer.

Expert Opin Pharmacother 2014 Apr;15(6):889-903

UOS Tumori Polmonari, IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro , L.go Benzi 10, Genova 16132 , Italy

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http://dx.doi.org/10.1517/14656566.2014.902445DOI Listing
April 2014

Role of immunotherapy in the treatment of advanced non-small-cell lung cancer.

Future Oncol 2014 Jan;10(1):79-90

UOS Tumori Polmonari, IRCCS AOU San Martino IST - Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.

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http://dx.doi.org/10.2217/fon.13.145DOI Listing
January 2014

Pemetrexed for the treatment of non-small cell lung cancer.

Expert Opin Pharmacother 2013 Aug 17;14(11):1545-58. Epub 2013 May 17.

IRCCS AOU San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Lung Cancer Unit, Genova, Italy.

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http://dx.doi.org/10.1517/14656566.2013.802774DOI Listing
August 2013

Epigenetic Silencing of DKK3 in medulloblastoma.

Int J Mol Sci 2013 Apr 8;14(4):7492-505. Epub 2013 Apr 8.

Department of Experimental Medicine (DIMES), University of Genoa-IRCCS A.O.U. San Martino-IST National Cancer Research Institute, Genoa 16132, Italy.

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http://dx.doi.org/10.3390/ijms14047492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645699PMC
April 2013

Age-dependent accumulation of genomic aberrations and deregulation of cell cycle and telomerase genes in metastatic neuroblastoma.

Int J Cancer 2012 Oct 18;131(7):1591-600. Epub 2012 Feb 18.

Department of Advanced Diagnostic Technologies IRCCS AOU San Martino, IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.

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http://doi.wiley.com/10.1002/ijc.27432
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http://dx.doi.org/10.1002/ijc.27432DOI Listing
October 2012

Identification of ALK germline mutation (3605delG) in pediatric anaplastic medulloblastoma.

J Hum Genet 2012 Oct 19;57(10):682-4. Epub 2012 Jul 19.

Translational Oncopathology, Department of Pathology, IRCCS A.O.U. San Martino-IST, National Cancer Research Institute, Genoa, Italy.

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http://dx.doi.org/10.1038/jhg.2012.87DOI Listing
October 2012

High genomic instability predicts survival in metastatic high-risk neuroblastoma.

Neoplasia 2012 Sep;14(9):823-32

Center of Physiopathology of Human Reproduction, Department of Obstetrics and Gynecology, IRCCS San Martino Hospital, National Cancer Research Institute (IST), Genoa, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459278PMC
http://dx.doi.org/10.1593/neo.121114DOI Listing
September 2012

Dissecting the genomic complexity underlying medulloblastoma.

Nature 2012 Aug;488(7409):100-5

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1038/nature11284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662966PMC
August 2012

Transcribed-ultra conserved region expression profiling from low-input total RNA.

BMC Genomics 2010 Mar 3;11:149. Epub 2010 Mar 3.

Translational Paediatric Oncology, National Cancer Research Institute (IST), Largo R Benzi 10, Genoa, 16132, Italy.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-11-149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838852PMC
March 2010

Identification and characterization of DNA imbalances in neuroblastoma by high-resolution oligonucleotide array comparative genomic hybridization.

Cancer Genet Cytogenet 2007 Aug;177(1):20-9

Translational Paediatric Oncology, National Institute for Cancer Research (IST), L.go R. Benzi, 10, 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.cancergencyto.2007.05.002DOI Listing
August 2007

Oligonucleotide Array Comparative Genomic Hybridization Profiling of Neuroblastoma Tumours.

Cancer Genomics Proteomics 2006 May-Aug;3(3-4):245-252. Epub 2006 Jan 1.

Unit of Translational Paediatric Oncology, National Institute for Cancer Research (IST), Genoa.

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January 2006

Glutathione S-transferase polymorphisms and susceptibility to neuroblastoma.

Pharmacogenet Genomics 2005 Jun;15(6):423-6

Department of Pediatric Hemato-Oncology, National Institute Cancer Research (IST), Genoa, Italy.

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http://pdfs.journals.lww.com/jpharmacogenetics/2005/06000/Gl
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June 2005

Familial neuroblastoma: a complex heritable disease.

Cancer Lett 2003 Jul;197(1-2):41-5

Laboratory of Tumor Genetics, Istituto Nazionale per la Ricerca sul Cancro (IST), 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/s0304-3835(03)00080-6DOI Listing
July 2003