Simon de Denus

Simon de Denus

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Simon de Denus

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Is there a potential association between spironolactone and the risk of new-onset diabetes in a cohort of older patients with heart failure?

Eur J Clin Pharmacol 2019 Jun 13;75(6):837-847. Epub 2019 Feb 13.

Faculty of Pharmacy, Université de Montréal, Case Postale 6128, Succursale Centre-Ville, Montréal, QC, H3C 3J7, Canada.

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http://dx.doi.org/10.1007/s00228-018-02615-8DOI Listing
June 2019

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Authors:
Anne E Justice Tugce Karaderi Heather M Highland Kristin L Young Mariaelisa Graff Yingchang Lu Valérie Turcot Paul L Auer Rebecca S Fine Xiuqing Guo Claudia Schurmann Adelheid Lempradl Eirini Marouli Anubha Mahajan Thomas W Winkler Adam E Locke Carolina Medina-Gomez Tõnu Esko Sailaja Vedantam Ayush Giri Ken Sin Lo Tamuno Alfred Poorva Mudgal Maggie C Y Ng Nancy L Heard-Costa Mary F Feitosa Alisa K Manning Sara M Willems Suthesh Sivapalaratnam Goncalo Abecasis Dewan S Alam Matthew Allison Philippe Amouyel Zorayr Arzumanyan Beverley Balkau Lisa Bastarache Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Erwin P Bottinger Donald W Bowden Ivan Brandslund Linda Broer Amber A Burt Adam S Butterworth Mark J Caulfield Giancarlo Cesana John C Chambers Daniel I Chasman Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Francis S Collins James P Cook Amanda J Cox David S Crosslin John Danesh Paul I W de Bakker Simon de Denus Renée de Mutsert George Dedoussis Ellen W Demerath Joe G Dennis Josh C Denny Emanuele Di Angelantonio Marcus Dörr Fotios Drenos Marie-Pierre Dubé Alison M Dunning Douglas F Easton Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Myriam Fornage Caroline S Fox Paul W Franks Nele Friedrich Wei Gan Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Giorgia Girotto Mathias Gorski Harald Grallert Niels Grarup Megan L Grove Stefan Gustafsson Jeff Haessler Torben Hansen Andrew T Hattersley Caroline Hayward Iris M Heid Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Yi-Jen Hung Kristian Hveem M Arfan Ikram Erik Ingelsson Anne U Jackson Gail P Jarvik Yucheng Jia Torben Jørgensen Pekka Jousilahti Johanne M Justesen Bratati Kahali Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Frank Kee Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Peter Kovacs Bernhard K Krämer Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Wen-Jane Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Jian'an Luan Leo-Pekka Lyytikäinen Stuart MacGregor Reedik Mägi Satu Männistö Gaëlle Marenne Jonathan Marten Nicholas G D Masca Mark I McCarthy Karina Meidtner Evelin Mihailov Leena Moilanen Marie Moitry Dennis O Mook-Kanamori Anna Morgan Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Narisu Narisu Christopher P Nelson Matt Neville Ioanna Ntalla Jeffrey R O'Connell Katharine R Owen Oluf Pedersen Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Ailith Ewing Ozren Polasek Olli T Raitakari Asif Rasheed Chelsea K Raulerson Rainer Rauramaa Dermot F Reilly Alex P Reiner Paul M Ridker Manuel A Rivas Neil R Robertson Antonietta Robino Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo Segura-Lepe Xueling Sim Andrew J Slater Kerrin S Small Blair H Smith Jennifer A Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Karin M A Swart Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Mina Torres Emmanouil Tsafantakis Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Cornelia M van Duijn Mauno Vanhala Rohit Varma Sita H Vermeulen Henrik Vestergaard Veronique Vitart Thomas F Vogt Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao He Zheng Wei Zhou M Carola Zillikens Fernando Rivadeneira Ingrid B Borecki J Andrew Pospisilik Panos Deloukas Timothy M Frayling Guillaume Lettre Karen L Mohlke Jerome I Rotter Zoltán Kutalik Joel N Hirschhorn L Adrienne Cupples Ruth J F Loos Kari E North Cecilia M Lindgren

Nat Genet 2019 03 18;51(3):452-469. Epub 2019 Feb 18.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41588-018-0334-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560635PMC
March 2019

Sex, drugs, and heart failure: a sex-sensitive review of the evidence base behind current heart failure clinical guidelines.

ESC Heart Fail 2018 10 19;5(5):745-754. Epub 2018 Jun 19.

Beaulieu-Saucier Université de Montréal Pharmacogenomics Centre, Montreal, Quebec, Canada.

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http://doi.wiley.com/10.1002/ehf2.12307
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http://dx.doi.org/10.1002/ehf2.12307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165928PMC
October 2018

Cardiopulmonary, biomarkers, and vascular responses to acute hypoxia following cardiac transplantation.

Clin Transplant 2018 09 18;32(9):e13352. Epub 2018 Aug 18.

Cardiology Department, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1111/ctr.13352DOI Listing
September 2018

Subclinical Inflammation in Heart Failure: A Neutrophil Perspective.

Can J Cardiol 2018 06 31;34(6):717-725. Epub 2018 Jan 31.

Research Center, Montreal Heart Institute, Université de Montréal, Montreal, Québec, Canada; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, Québec, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Québec, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0828282X183003
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http://dx.doi.org/10.1016/j.cjca.2018.01.018DOI Listing
June 2018

CKing Precision in the Interpretation of Diagnostic Biomarkers.

Circ Cardiovasc Genet 2017 08;10(4)

From the Research Center, Montreal Heart Institute, Montreal, Quebec, Canada (S.d.D., J.-C.T., M.-P.D.); Université de Montréal Beaulieu-Saucier Pharmacogenomics Center, Montreal, Quebec, Canada (S.d.D., J.-C.T., M.-P.D.); and Faculties of Pharmacy (S.d.D.) and Medicine (J.-C.T., M.-P.D.), Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1161/CIRCGENETICS.117.001874DOI Listing
August 2017

Drug Shortages: Patients and Health Care Providers Are All Drawing the Short Straw.

Can J Cardiol 2017 02 17;33(2):283-286. Epub 2016 Aug 17.

Département de pharmacie et Unité de recherche en pratique pharmaceutique, CHU Sainte-Justine, Montréal, Québec, Canada; Faculty of Pharmacy, Université de Montréal, Montréal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2016.08.010DOI Listing
February 2017

Rare and low-frequency coding variants alter human adult height.

Authors:
Eirini Marouli Mariaelisa Graff Carolina Medina-Gomez Ken Sin Lo Andrew R Wood Troels R Kjaer Rebecca S Fine Yingchang Lu Claudia Schurmann Heather M Highland Sina Rüeger Gudmar Thorleifsson Anne E Justice David Lamparter Kathleen E Stirrups Valérie Turcot Kristin L Young Thomas W Winkler Tõnu Esko Tugce Karaderi Adam E Locke Nicholas G D Masca Maggie C Y Ng Poorva Mudgal Manuel A Rivas Sailaja Vedantam Anubha Mahajan Xiuqing Guo Goncalo Abecasis Katja K Aben Linda S Adair Dewan S Alam Eva Albrecht Kristine H Allin Matthew Allison Philippe Amouyel Emil V Appel Dominique Arveiler Folkert W Asselbergs Paul L Auer Beverley Balkau Bernhard Banas Lia E Bang Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Heiner Boeing Eric Boerwinkle Carsten A Böger Lori L Bonnycastle Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Amber A Burt Adam S Butterworth David J Carey Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox Gabriel Cuellar-Partida John Danesh Gail Davies Paul I W de Bakker Gert J de Borst Simon de Denus Mark C H de Groot Renée de Mutsert Ian J Deary George Dedoussis Ellen W Demerath Anneke I den Hollander Joe G Dennis Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Alison M Dunning Douglas F Easton Tapani Ebeling Todd L Edwards Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki Jessica D Faul Mary F Feitosa Shuang Feng Ele Ferrannini Marco M Ferrario Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Paul W Franks Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Ayush Giri Giorgia Girotto Scott D Gordon Penny Gordon-Larsen Mathias Gorski Niels Grarup Megan L Grove Vilmundur Gudnason Stefan Gustafsson Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Caroline Hayward Liang He Iris M Heid Kauko Heikkilä Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Lynne J Hocking Mette Hollensted Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Carel B Hoyng Paul L Huang Kristian Hveem M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Min A Jhun Yucheng Jia Xuejuan Jiang Stefan Johansson Marit E Jørgensen Torben Jørgensen Pekka Jousilahti J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Frank Kee Renske Keeman Lambertus A Kiemeney Hidetoshi Kitajima Kirsten B Kluivers Thomas Kocher Pirjo Komulainen Jukka Kontto Jaspal S Kooner Charles Kooperberg Peter Kovacs Jennifer Kriebel Helena Kuivaniemi Sébastien Küry Johanna Kuusisto Martina La Bianca Markku Laakso Timo A Lakka Ethan M Lange Leslie A Lange Carl D Langefeld Claudia Langenberg Eric B Larson I-Te Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Yeheng Liu Yongmei Liu Artitaya Lophatananon Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen David A Mackey Pamela A F Madden Alisa K Manning Satu Männistö Gaëlle Marenne Jonathan Marten Nicholas G Martin Angela L Mazul Karina Meidtner Andres Metspalu Paul Mitchell Karen L Mohlke Dennis O Mook-Kanamori Anna Morgan Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Matthias Nauck Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Ioanna Ntalla Jeffrey R O'Connel Heikki Oksa Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Thomas N Person Ailith Pirie Ozren Polasek Danielle Posthuma Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Alex P Reiner Frida Renström Paul M Ridker John D Rioux Neil Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Kevin Sandow Yadav Sapkota Naveed Sattar Marjanka K Schmidt Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati Shah Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Albert Vernon Smith Jennifer A Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Valgerdur Steinthorsdottir Heather M Stringham Michael Stumvoll Praveen Surendran Leen M 't Hart Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Sheila Ulivi Sander W van der Laan Andries R Van Der Leij Cornelia M van Duijn Natasja M van Schoor Jessica van Setten Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Henrik Vestergaard Veronique Vitart Thomas F Vogt Diego Vozzi Mark Walker Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Nicholas J Wareham Helen R Warren Jennifer Wessel Sara M Willems James G Wilson Daniel R Witte Michael O Woods Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao He Zheng Wei Zhou Jerome I Rotter Michael Boehnke Sekar Kathiresan Mark I McCarthy Cristen J Willer Kari Stefansson Ingrid B Borecki Dajiang J Liu Kari E North Nancy L Heard-Costa Tune H Pers Cecilia M Lindgren Claus Oxvig Zoltán Kutalik Fernando Rivadeneira Ruth J F Loos Timothy M Frayling Joel N Hirschhorn Panos Deloukas Guillaume Lettre

Nature 2017 02 1;542(7640):186-190. Epub 2017 Feb 1.

Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.

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http://dx.doi.org/10.1038/nature21039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302847PMC
February 2017

Ivabradine for the treatment of chronic heart failure.

Expert Rev Cardiovasc Ther 2016 28;14(5):553-61. Epub 2016 Mar 28.

a Research Center and Department of Medicine, Montreal Heart Institute , Université de Montréal , Montréal , Québec , Canada.

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http://dx.doi.org/10.1586/14779072.2016.1165092DOI Listing
December 2016

Pharmacogenomics of heart failure: a systematic review.

Pharmacogenomics 2016 11 4;17(16):1817-1858. Epub 2016 Nov 4.

Faculty of Pharmacy, Université de Montréal, Montreal, Canada.

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http://dx.doi.org/10.2217/pgs-2016-0118DOI Listing
November 2016

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.

Authors:
Nathalie Chami Ming-Huei Chen Andrew J Slater John D Eicher Evangelos Evangelou Salman M Tajuddin Latisha Love-Gregory Tim Kacprowski Ursula M Schick Akihiro Nomura Ayush Giri Samuel Lessard Jennifer A Brody Claudia Schurmann Nathan Pankratz Lisa R Yanek Ani Manichaikul Raha Pazoki Evelin Mihailov W David Hill Laura M Raffield Amber Burt Traci M Bartz Diane M Becker Lewis C Becker Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Michelle L O'Donoghue David R Crosslin Simon de Denus Marie-Pierre Dubé Paul Elliott Gunnar Engström Michele K Evans James S Floyd Myriam Fornage He Gao Andreas Greinacher Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Jussi Hernesniemi Heather M Highland Joel N Hirschhorn Albert Hofman Marguerite R Irvin Mika Kähönen Ethan Lange Lenore J Launer Terho Lehtimäki Jin Li David C M Liewald Allan Linneberg Yongmei Liu Yingchang Lu Leo-Pekka Lyytikäinen Reedik Mägi Rasika A Mathias Olle Melander Andres Metspalu Nina Mononen Mike A Nalls Deborah A Nickerson Kjell Nikus Chris J O'Donnell Marju Orho-Melander Oluf Pedersen Astrid Petersmann Linda Polfus Bruce M Psaty Olli T Raitakari Emma Raitoharju Melissa Richard Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Frank Schmidt Albert Vernon Smith John M Starr Kent D Taylor Alexander Teumer Betina H Thuesen Eric S Torstenson Russell P Tracy Ioanna Tzoulaki Neil A Zakai Caterina Vacchi-Suzzi Cornelia M van Duijn Frank J A van Rooij Mary Cushman Ian J Deary Digna R Velez Edwards Anne-Claire Vergnaud Lars Wallentin Dawn M Waterworth Harvey D White James G Wilson Alan B Zonderman Sekar Kathiresan Niels Grarup Tõnu Esko Ruth J F Loos Leslie A Lange Nauder Faraday Nada A Abumrad Todd L Edwards Santhi K Ganesh Paul L Auer Andrew D Johnson Alexander P Reiner Guillaume Lettre

Am J Hum Genet 2016 Jul 23;99(1):8-21. Epub 2016 Jun 23.

Department of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada; Montreal Heart Institute, Montréal, QC H1T 1C8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005438PMC
July 2016

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.

Authors:
John D Eicher Nathalie Chami Tim Kacprowski Akihiro Nomura Ming-Huei Chen Lisa R Yanek Salman M Tajuddin Ursula M Schick Andrew J Slater Nathan Pankratz Linda Polfus Claudia Schurmann Ayush Giri Jennifer A Brody Leslie A Lange Ani Manichaikul W David Hill Raha Pazoki Paul Elliot Evangelos Evangelou Ioanna Tzoulaki He Gao Anne-Claire Vergnaud Rasika A Mathias Diane M Becker Lewis C Becker Amber Burt David R Crosslin Leo-Pekka Lyytikäinen Kjell Nikus Jussi Hernesniemi Mika Kähönen Emma Raitoharju Nina Mononen Olli T Raitakari Terho Lehtimäki Mary Cushman Neil A Zakai Deborah A Nickerson Laura M Raffield Rakale Quarells Cristen J Willer Gina M Peloso Goncalo R Abecasis Dajiang J Liu Panos Deloukas Nilesh J Samani Heribert Schunkert Jeanette Erdmann Myriam Fornage Melissa Richard Jean-Claude Tardif John D Rioux Marie-Pierre Dube Simon de Denus Yingchang Lu Erwin P Bottinger Ruth J F Loos Albert Vernon Smith Tamara B Harris Lenore J Launer Vilmundur Gudnason Digna R Velez Edwards Eric S Torstenson Yongmei Liu Russell P Tracy Jerome I Rotter Stephen S Rich Heather M Highland Eric Boerwinkle Jin Li Ethan Lange James G Wilson Evelin Mihailov Reedik Mägi Joel Hirschhorn Andres Metspalu Tõnu Esko Caterina Vacchi-Suzzi Mike A Nalls Alan B Zonderman Michele K Evans Gunnar Engström Marju Orho-Melander Olle Melander Michelle L O'Donoghue Dawn M Waterworth Lars Wallentin Harvey D White James S Floyd Traci M Bartz Kenneth M Rice Bruce M Psaty J M Starr David C M Liewald Caroline Hayward Ian J Deary Andreas Greinacher Uwe Völker Thomas Thiele Henry Völzke Frank J A van Rooij André G Uitterlinden Oscar H Franco Abbas Dehghan Todd L Edwards Santhi K Ganesh Sekar Kathiresan Nauder Faraday Paul L Auer Alex P Reiner Guillaume Lettre Andrew D Johnson

Am J Hum Genet 2016 Jul 23;99(1):40-55. Epub 2016 Jun 23.

Population Sciences Branch, National Heart Lung and Blood Institute, The Framingham Heart Study, Framingham, MA 01702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005441PMC
July 2016

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.

Authors:
Salman M Tajuddin Ursula M Schick John D Eicher Nathalie Chami Ayush Giri Jennifer A Brody W David Hill Tim Kacprowski Jin Li Leo-Pekka Lyytikäinen Ani Manichaikul Evelin Mihailov Michelle L O'Donoghue Nathan Pankratz Raha Pazoki Linda M Polfus Albert Vernon Smith Claudia Schurmann Caterina Vacchi-Suzzi Dawn M Waterworth Evangelos Evangelou Lisa R Yanek Amber Burt Ming-Huei Chen Frank J A van Rooij James S Floyd Andreas Greinacher Tamara B Harris Heather M Highland Leslie A Lange Yongmei Liu Reedik Mägi Mike A Nalls Rasika A Mathias Deborah A Nickerson Kjell Nikus John M Starr Jean-Claude Tardif Ioanna Tzoulaki Digna R Velez Edwards Lars Wallentin Traci M Bartz Lewis C Becker Joshua C Denny Laura M Raffield John D Rioux Nele Friedrich Myriam Fornage He Gao Joel N Hirschhorn David C M Liewald Stephen S Rich Andre Uitterlinden Lisa Bastarache Diane M Becker Eric Boerwinkle Simon de Denus Erwin P Bottinger Caroline Hayward Albert Hofman Georg Homuth Ethan Lange Lenore J Launer Terho Lehtimäki Yingchang Lu Andres Metspalu Chris J O'Donnell Rakale C Quarells Melissa Richard Eric S Torstenson Kent D Taylor Anne-Claire Vergnaud Alan B Zonderman David R Crosslin Ian J Deary Marcus Dörr Paul Elliott Michele K Evans Vilmundur Gudnason Mika Kähönen Bruce M Psaty Jerome I Rotter Andrew J Slater Abbas Dehghan Harvey D White Santhi K Ganesh Ruth J F Loos Tõnu Esko Nauder Faraday James G Wilson Mary Cushman Andrew D Johnson Todd L Edwards Neil A Zakai Guillaume Lettre Alex P Reiner Paul L Auer

Am J Hum Genet 2016 Jul 23;99(1):22-39. Epub 2016 Jun 23.

Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI 53205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005433PMC
July 2016

Will personalized drugs for cardiovascular disease become an option? - Defining 'Evidence-based personalized medicine' for its implementation and future use.

Expert Opin Pharmacother 2015 15;16(17):2549-52. Epub 2015 Sep 15.

b 2 Université de Montréal Beaulieu-Saucier Pharmacogenomics Center , Montreal, Canada.

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http://dx.doi.org/10.1517/14656566.2015.1088829DOI Listing
June 2016

Genetic markers associated with cutaneous adverse drug reactions to allopurinol: a systematic review.

Pharmacogenomics 2015 12;16(7):755-67. Epub 2015 May 12.

1Faculty of Pharmacy, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal QC H3T 1J4, Canada.

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https://www.futuremedicine.com/doi/10.2217/pgs.15.21
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http://dx.doi.org/10.2217/pgs.15.21DOI Listing
March 2016

Heart Failure, Iron Deficiency, and Supplementation: Where Do We Stand?

Can J Cardiol 2016 Feb 12;32(2):148-50. Epub 2015 Aug 12.

Department of Cardiology, Centre Hospitalier Universitaire de l'Université de Sherbrooke, Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.1016/j.cjca.2015.07.725DOI Listing
February 2016

Pharmacogenomics to Revive Drug Development in Cardiovascular Disease.

Cardiovasc Drugs Ther 2016 Feb;30(1):59-64

Montreal Heart Institute, 5000 Belanger Street, Montreal, QC, H1T 1C8, Canada.

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http://dx.doi.org/10.1007/s10557-015-6637-yDOI Listing
February 2016

Risk Factors for Chronic Renal Insufficiency Following Cardiac Transplantation.

Ann Transplant 2015 Sep 29;20:576-87. Epub 2015 Sep 29.

Faculty of Pharmacy, Université de Montréal, Montreal, QC, Canada.

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http://dx.doi.org/10.12659/AOT.893788DOI Listing
September 2015

CKM and LILRB5 are associated with serum levels of creatine kinase.

Circ Cardiovasc Genet 2014 Dec 11;7(6):880-6. Epub 2014 Sep 11.

From the Montreal Heart Institute, Montreal, Quebec, Canada (M.-P.D., R.Z., A.B., A.M.K.B., I.M., V.N., N.L., G.A., Y.F.Z., S.P., S.d.D., E.R., M.S.P., J.-C.T.); Université de Montréal, Montreal, Quebec, Canada (M.-P.D., R.Z., A.B., R.D., S.d.D., J.T., E.R., M.S.P., J.-C.T.); Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Quebec, Canada (M.-P.D., R.Z., A.B., I.M., A.M.K.B. V.N., G.A., Y.F.Z., S.P., S.d.D., M.S.P., J.-C.T.); Centre Hospitalier du CHU de Québec, Quebec city, Quebec, Canada (J.B.); Centre Hospitalier Régional de Lanaudière, Saint-Charles-Borromée, Quebec, Canada (S.K.); Institut de recherches cliniques de Montréal, Montreal, Quebec, Canada (R.D.); Centre de Santé et de Services Sociaux de Trois-Rivieères, Centre Hospitalier Affilié Universitaire Régional, Trois-Rivières, Quebec, Canada (A.D.); and Centre de recherche du CHUM, Montreal, Quebec, Canada (J.T.).

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http://dx.doi.org/10.1161/CIRCGENETICS.113.000395DOI Listing
December 2014

Heart failure with anemia: novel findings on the roles of renal disease, interleukins, and specific left ventricular remodeling processes.

Circ Heart Fail 2014 Sep 15;7(5):773-81. Epub 2014 Jul 15.

From the Montreal Heart Institute, Department of Medicine (E.O'M., J.L.R., M.W., K.R., A.D., J.L., N.R., M.L., J.-C.T., S.d.D.), Department of Pharmacology (P.-E.N., M.G.S.), Department of Biostatistics Montreal Heart Innovations Coordinating Center (MHICC) (L.B.), and Department of Nephrology, Hôpital du Sacré-Cœur de Montréal (F.M.), Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001100DOI Listing
September 2014

Long-term evolution, secular trends, and risk factors of renal dysfunction following cardiac transplantation.

Transpl Int 2014 Aug 26;27(8):824-37. Epub 2014 May 26.

Montreal Heart Institute, Montreal, QC, Canada; Faculty of Pharmacy, Université de Montréal, Montreal, QC, Canada.

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http://dx.doi.org/10.1111/tri.12340DOI Listing
August 2014

Regional variability in β-blocker efficacy and safety: a question of "location, location, location"?

Can J Cardiol 2014 Aug 13;30(8):858-60. Epub 2014 May 13.

Montreal Heart Institute, Montreal, Québec, Canada; Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada.

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http://dx.doi.org/10.1016/j.cjca.2014.05.008DOI Listing
August 2014

Sirolimus Immunoprophylaxis and Renal Histological Changes in Long-Term Cardiac Transplant Recipients: A Pilot Study.

Ann Pharmacother 2014 Jul 16;48(7):837-846. Epub 2014 Apr 16.

Hôpital Maisonneuve-Rosemont, Université de Montréal, Montréal, Canada.

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http://dx.doi.org/10.1177/1060028014527723DOI Listing
July 2014

Changes in cardiopulmonary reserve and peripheral arterial function concomitantly with subclinical inflammation and oxidative stress in patients with heart failure with preserved ejection fraction.

Int J Vasc Med 2014 27;2014:917271. Epub 2014 Feb 27.

Research Center, Montreal Heart Institute, Université de Montréal, 5000 Belanger Street East, Montreal, QC, Canada H1T 1C8 ; Departments of Medicine and Pharmacology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.

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http://dx.doi.org/10.1155/2014/917271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955597PMC
April 2014

Personalizing the management of heart failure in congenital heart disease: challenges and opportunities.

Pharmacogenomics 2014 Feb;15(2):123-7

Faculty of Pharmacy, Université de Montréal, Montreal, Canada and Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec H1T 1C8, Canada.

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http://dx.doi.org/10.2217/pgs.13.215DOI Listing
February 2014

Pharmacogenomics and heart failure in congenital heart disease.

Can J Cardiol 2013 Jul;29(7):779-85

Faculty of Pharmacy, Université de Montréal, Montreal Heart Institute, Montreal, Québec, Canada.

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http://dx.doi.org/10.1016/j.cjca.2013.04.017DOI Listing
July 2013

Disclosure of individual pharmacogenomic results in research projects: when and what kind of information to return to research participants.

Pharmacogenomics 2013 Apr;14(6):675-88

Faculty of Pharmacy, Université de Montréal, Montreal, Canada.

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http://dx.doi.org/10.2217/pgs.13.50DOI Listing
April 2013

Differences in biomarkers in patients with heart failure with a reduced vs a preserved left ventricular ejection fraction.

Can J Cardiol 2012 Jan-Feb;28(1):62-8. Epub 2011 Nov 21.

Research Center, Montreal Heart Institute and Université de Montréal, Montréal, Québec, Canada.

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http://dx.doi.org/10.1016/j.cjca.2011.09.007DOI Listing
March 2012

Management of anemia and iron deficiency in heart failure.

Curr Treat Options Cardiovasc Med 2010 Dec;12(6):532-48

Montreal Heart Institute, 5000 Belanger Street, Montreal, QC, Canada, H1T 1C8,

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http://dx.doi.org/10.1007/s11936-010-0095-4DOI Listing
December 2010

Systematic review of pharmacoeconomic studies of pharmacogenomic tests.

Pharmacogenomics 2010 Nov;11(11):1573-90

Faculté de Pharmacie, Université de Montréal, PO Box 6128, succ. Centre-Ville, Montréal, Québec, H3C 3J7, Canada.

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http://dx.doi.org/10.2217/pgs.10.145DOI Listing
November 2010

Enantioselective quantification of carvedilol in human plasma by HPLC in heavily medicated heart failure patients.

J Pharm Biomed Anal 2010 Aug 10;52(4):636-41. Epub 2010 Feb 10.

Hôpital Hôtel-Dieu, pavillon Jeanne-Mance, Labo 7-017, 3850 rue Saint-Urbain, Montréal, Canada H2W 1T7.

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http://dx.doi.org/10.1016/j.jpba.2010.02.002DOI Listing
August 2010

Key articles and guidelines in the management of hypertension: 2008 update.

Pharmacotherapy 2008 Aug;28(8):1041-58

Department of Pharmacy, Northeast Georgia Health System, 743 Spring Street, Gainesville, GA 30501, USA.

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http://dx.doi.org/10.1592/phco.28.8.1041DOI Listing
August 2008

Rate vs rhythm control in patients with atrial fibrillation: a meta-analysis.

Arch Intern Med 2005 Feb;165(3):258-62

Pharmacy Department, Montreal Heart Institute/Faculty of Pharmacy, University of Montreal, Montreal, Quebec.

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http://dx.doi.org/10.1001/archinte.165.3.258DOI Listing
February 2005

Dyslipidemias and HMG-CoA reductase inhibitor prescription in heart transplant recipients.

Ann Pharmacother 2004 Jul-Aug;38(7-8):1136-41. Epub 2004 May 18.

Fellow in Cardiovascular Pharmacotherapy, Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, PA 19103-4495, USA.

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http://dx.doi.org/10.1345/aph.1D535DOI Listing
October 2004

History of depression as a predictor of adverse outcomes in patients hospitalized for decompensated heart failure.

Pharmacotherapy 2004 Oct;24(10):1306-10

Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, Philadelphia, Pennsylvania 19104, USA.

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October 2004

Key articles and guidelines in the management of hypertension.

Pharmacotherapy 2004 Oct;24(10):1385-99

Montreal Heart Institute and the Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada.

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October 2004

Statins and liver toxicity: a meta-analysis.

Pharmacotherapy 2004 May;24(5):584-91

Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, PA 19103-4495, USA.

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May 2004

Plasma cholesterol concentrations, dietary fat intake, and cholesterol intake in pharmacy students.

J Am Pharm Assoc (2003) 2003 Sep-Oct;43(5):590-5

Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, 600 S. 43rd Street, Philadelphia, PA 19104, USA.

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February 2004

Brain natriuretic peptide in the management of heart failure: the versatile neurohormone.

Chest 2004 Feb;125(2):652-68

Philadelphia College of Pharmacy, University of Sciences of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1378/chest.125.2.652DOI Listing
February 2004

Decreased argatroban clearance unaffected by hemodialysis in anasarca.

Ann Pharmacother 2003 Sep;37(9):1237-40

Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, Philadelphia, PA 19104, USA.

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http://journals.sagepub.com/doi/10.1345/aph.1C493
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http://dx.doi.org/10.1345/aph.1C493DOI Listing
September 2003

Amiodarone's role in simvastatin-associated rhabdomyolysis.

Am J Health Syst Pharm 2003 Sep;60(17):1791; author reply 1791-2

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September 2003

Optimal digoxin concentrations for patients with heart failure.

JAMA 2003 May;289(20):2643; author reply 2643-4

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http://dx.doi.org/10.1001/jama.289.20.2643-bDOI Listing
May 2003

Early statin therapy for acute coronary syndromes.

Ann Pharmacother 2002 Nov;36(11):1749-58

Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1345/aph.1A413DOI Listing
November 2002

Treatment of congestive heart failure.

JAMA 2002 May;287(17):2209; author reply 2210

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May 2002

Clinical monitoring of direct thrombin inhibitors using the ecarin clotting time.

Pharmacotherapy 2002 Apr;22(4):433-5

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April 2002

Removal of lepirudin, a recombinant hirudin, by hemodialysis, hemofiltration, or plasmapheresis.

Pharmacotherapy 2002 Apr;22(4):492-9

Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, PA 19104, USA.

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April 2002