Publications by authors named "Simon P Mooijaart"

100Publications

Feasibility and acceptability of the 'Acutely Presenting Older Patient' screener in routine emergency department care.

Age Ageing 2020 May 18. Epub 2020 May 18.

Department of Emergency Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/ageing/afaa078DOI Listing
May 2020

Geriatric Screeners 2.0: Time for a Paradigm Shift in Emergency Department Vulnerability Research.

J Am Geriatr Soc 2020 Jul 13;68(7):1402-1405. Epub 2020 May 13.

Department of Geriatrics and Gerontology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/jgs.16502DOI Listing
July 2020

Geriatric Screening, Triage Urgency, and 30-Day Mortality in Older Emergency Department Patients.

J Am Geriatr Soc 2020 Aug 4;68(8):1755-1762. Epub 2020 Apr 4.

Department of Internal Medicine, Section Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/jgs.16427DOI Listing
August 2020

Treatment of Older Adults With Subclinical Hypothyroidism-Reply.

JAMA 2020 03;323(11):1097-1098

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1001/jama.2020.0948DOI Listing
March 2020

Renal Impairment, Cardiovascular Disease, and the Short-Term Efficacy and Safety of PCSK9 Targeted by Inclisiran.

Mayo Clin Proc 2020 01;95(1):12-14

Department of Cardiology, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1016/j.mayocp.2019.11.010DOI Listing
January 2020

The Challenges of Managing Inflammatory Bowel Diseases in Older Patients.

Clin Gastroenterol Hepatol 2020 Jun 27;18(7):1648-1649. Epub 2019 Dec 27.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Institute for Evidence-Based Medicine in Old Age, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.cgh.2019.12.023DOI Listing
June 2020

PCSK9 inhibition in high-risk patients.

Aging (Albany NY) 2019 12 11;11(23):10791-10792. Epub 2019 Dec 11.

Department of Cardiology Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.18632/aging.102621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932888PMC
December 2019

[Screening for vulnerability in older adults attending the emergency department].

Ned Tijdschr Geneeskd 2019 11 14;163. Epub 2019 Nov 14.

LUMC, afd. Interne Geneeskunde, sectie Ouderengeneeskunde, Leiden.

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November 2019

[Assessment instruments in frail older patients; a call for more standardisation].

Ned Tijdschr Geneeskd 2019 11 12;163. Epub 2019 Nov 12.

Gelre Ziekenhuizen, afd. Klinische Geriatrie, Apeldoorn.

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November 2019

Recommendations for (Discontinuation of) Statin Treatment in Older Adults: Review of Guidelines.

J Am Geriatr Soc 2020 02 30;68(2):417-425. Epub 2019 Oct 30.

Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/jgs.16219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027549PMC
February 2020

The association between intravenous fluid resuscitation and mortality in older emergency department patients with suspected infection.

Int J Emerg Med 2019 Jan 5;12(1). Epub 2019 Jan 5.

Department of Emergency Medicine, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, the Netherlands.

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http://dx.doi.org/10.1186/s12245-018-0219-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326108PMC
January 2019

Geriatric assessment and 1-year mortality in older patients with cancer in the head and neck region: A cohort study.

Head Neck 2019 08 28;41(8):2477-2483. Epub 2019 Feb 28.

Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/hed.25714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766841PMC
August 2019

Geriatric emergency medicine: time for a new approach on a European level.

Eur J Emerg Med 2019 04;26(2):75-76

Department of Emergency Medicine, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1097/MEJ.0000000000000594DOI Listing
April 2019

Acute care assessment of older adults living with frailty.

BMJ 2019 Jan 31;364:l13. Epub 2019 Jan 31.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1136/bmj.l13DOI Listing
January 2019

Spatial QRS-T Angle and Cognitive Decline in Older Subjects.

J Alzheimers Dis 2019 ;67(1):279-289

Department of Internal Medicine, Gerontology and Geriatrics Section, Leiden University Medical Center, Leiden, The Netherlands.

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https://www.medra.org/servlet/aliasResolver?alias=iospress&a
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http://dx.doi.org/10.3233/JAD-180633DOI Listing
March 2020

The Six-Item Cognitive Impairment Test Is Associated with Adverse Outcomes in Acutely Hospitalized Older Patients: A Prospective Cohort Study.

Dement Geriatr Cogn Dis Extra 2018 May-Aug;8(2):259-267. Epub 2018 Jul 12.

Section of Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.

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https://www.karger.com/Article/FullText/490240
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http://dx.doi.org/10.1159/000490240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103363PMC
July 2018

Clinical aspects of thyroid function during ageing.

Lancet Diabetes Endocrinol 2018 09 17;6(9):733-742. Epub 2018 Jul 17.

Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(18)30028-7DOI Listing
September 2018

Functional and cognitive impairment, social functioning, frailty and adverse health outcomes in older patients with esophageal cancer, a systematic review.

J Geriatr Oncol 2018 11 19;9(6):560-568. Epub 2018 Apr 19.

Department of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands; Institute for Evidence-based Medicine in Old Age (IEMO), Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.jgo.2018.03.019DOI Listing
November 2018

Predictors and Outcomes of Revisits in Older Adults Discharged from the Emergency Department.

J Am Geriatr Soc 2018 04 28;66(4):735-741. Epub 2018 Feb 28.

Institute of Evidence-Based Medicine in Old Age, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/jgs.15301DOI Listing
April 2018

Regression discontinuity was a valid design for dichotomous outcomes in three randomized trials.

J Clin Epidemiol 2018 06 24;98:70-79. Epub 2018 Feb 24.

Center for Medical Decision Making, Department of Public Health, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands; Department of Medical Statistics and Bioinformatics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.jclinepi.2018.02.015DOI Listing
June 2018

Association of diastolic blood pressure with cardiovascular events in older people varies upon cardiovascular history.

J Hypertens 2018 04;36(4):773-778

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden.

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http://dx.doi.org/10.1097/HJH.0000000000001625DOI Listing
April 2018

Early prediction of hospital admission for emergency department patients: a comparison between patients younger or older than 70 years.

Emerg Med J 2018 Jan 16;35(1):18-27. Epub 2017 Aug 16.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/emermed-2016-205846DOI Listing
January 2018

The Cognitive decline in Older Patients with End stage renal disease (COPE) study - rationale and design.

Curr Med Res Opin 2017 11 11;33(11):2057-2064. Epub 2017 Jul 11.

a Department of Nephrology , Leiden University Medical Center , Leiden , The Netherlands.

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http://dx.doi.org/10.1080/03007995.2017.1341404DOI Listing
November 2017

Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.

N Engl J Med 2017 06 3;376(26):2534-2544. Epub 2017 Apr 3.

From the Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences (D.J.S., K.H., P.L., M. McDade, T.J.Q.), the Robertson Centre for Biostatistics, Institute of Health and Wellbeing (I.F., S.K., A.M., M. Messow, R.W.), and the Institute of Cardiovascular and Medical Sciences (N.S.), University of Glasgow, Glasgow, and Care of the Elderly-Rehabilitation, Monklands Hospital, NHS Lanarkshire, Airdrie (G.E.) - all in the United Kingdom; the Department of General Internal Medicine, Inselspital, Bern University Hospital (N.R., C.E.A., D.A., C.B., M.R.B., M.F., C.F., D.K., H.A.V.D.), and the Institute of Primary Health Care (N.R., M.F.), University of Bern, Bern, and the Service of Endocrinology, Diabetes, and Metabolism, University Hospital of Lausanne, Lausanne (T.-H.C.) - all in Switzerland; the Department of Epidemiology and Public Health (P.M.K., J.P.B., C.H., G.M., A.O., D.O., C.S., K.A.W., E.K.W.), the Pharmaceutical Care Research Group, School of Pharmacy (S.B., M.K., K.A.W.), the School of Nursing and Midwifery (V.M.), and the Department of General Practice (A.R., E.K.W.), University College Cork, and the Health Research Board Clinical Research Facility, Mercy University Hospital (M.K.) - all in Cork, Ireland; the Department of Public Health and Center for Healthy Aging, University of Copenhagen (R.G.J.W.), and the Department of Medical Endocrinology, Copenhagen University Hospital Rigshospitalet (T.W.), Copenhagen, and the Department of Internal Medicine, Copenhagen University Hospital Herlev, Herlev (T.W.) - all in Denmark; the Departments of Gerontology and Geriatrics (S.P.M.), Internal Medicine (O.M.D.), Clinical Epidemiology (O.M.D.), Clinical Chemistry and Laboratory Medicine (W.P.J.E.), Public Health and Primary Care (R.S.D.P., R.K.E.P., J.G.), and Cardiology (J.W.J.), Leiden University Medical Center, and the Institute for Evidence-based Medicine in Old Age (S.P.M.), Leiden, and Radboud University Medical Center, Nijmegen (J.W.A.S.) - all in the Netherlands; and the Departments of Medicine, Epidemiology, and Biostatistics, University of California, San Francisco, San Francisco (D.C.B.).

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http://dx.doi.org/10.1056/NEJMoa1603825DOI Listing
June 2017

Secondary phenotype analysis in ascertained family designs: application to the Leiden longevity study.

Stat Med 2017 06 16;36(14):2288-2301. Epub 2017 Mar 16.

Department of Medical Statistics and Bioinformatics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/sim.7281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485037PMC
June 2017

Complement receptor 1 gene polymorphisms are associated with cardiovascular risk.

Atherosclerosis 2017 02 20;257:16-21. Epub 2016 Dec 20.

Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094315PMC
February 2017

Functional and cognitive impairment, social environment, frailty and adverse health outcomes in older patients with head and neck cancer, a systematic review.

Oral Oncol 2017 01 1;64:27-36. Epub 2016 Dec 1.

Department of Gerontology and Geriatrics, Leiden University Medical Centre, The Netherlands; Institute for Evidence-based Medicine in Old Age (IEMO), Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.oraloncology.2016.11.013DOI Listing
January 2017

Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies.

J Clin Endocrinol Metab 2016 12 30;101(12):4945-4954. Epub 2016 Sep 30.

Department of General Internal Medicine (C.R., D.S., C.E.A., C.B., D.A., N.R.), Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland; Institute of Primary Health Care (BIHAM), Faculty of Medicine (B.R.d.C., N.R.), University of Bern, 3012 Bern, Switzerland; Service of Endocrinology, Diabetes and Metabolism (T.-H.C.), University Hospital of Lausanne, 1011 Lausanne, Switzerland; University of Cambridge Metabolic Research Laboratories (T.-H.C.), Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, United Kingdom; Department of Epidemiology (L.C., R.P.P.), Rotterdam Thyroid Center, 3015 GE Rotterdam, The Netherlands; School of Psychiatry and Clinical Neurosciences (O.P.A.), University of Western Australia, Perth 6009, Australia; School of Sport, Exercise and Health Sciences (E.H.), Loughborough University, Loughborough LE11 3TU, United Kingdom; Department of Cardiology (S.T.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; Kuakini Medical Center and the Department of Geriatric Medicine (K.M.), John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96817; Department of Gerontology and Geriatrics (S.P.M.), Leiden University Medical Center, Leiden and Institute for Evidence-based Medicine in Old Age (IEMO), 2333 ZA Leiden, The Netherlands; Department of Public Health and Primary Care (J.G.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; and Department of Medicine (D.C.B.), University of California-San Francisco, San Francisco California 94143.

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http://dx.doi.org/10.1210/jc.2016-2129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287525PMC
December 2016

Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity.

Exp Gerontol 2016 09 29;82:166-74. Epub 2016 Jun 29.

Department of Molecular Epidemiology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2016.06.013DOI Listing
September 2016

Functional and Cognitive Impairment, Frailty, and Adverse Health Outcomes in Older Patients Reaching ESRD-A Systematic Review.

Clin J Am Soc Nephrol 2016 09 24;11(9):1624-39. Epub 2016 Jun 24.

Gerontology and Geriatrics, and Institute for Evidence-Based Medicine in Old Age, Leiden, The Netherlands.

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http://dx.doi.org/10.2215/CJN.13611215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012494PMC
September 2016

Evaluation of the Use of Home Blood Pressure Measurement Using Mobile Phone-Assisted Technology: The iVitality Proof-of-Principle Study.

JMIR Mhealth Uhealth 2016 Jun 13;4(2):e67. Epub 2016 Jun 13.

Leiden University Medical Center, Department of Gerontology & Geriatrics, Leiden, Netherlands.

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http://dx.doi.org/10.2196/mhealth.5485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923587PMC
June 2016

Regression Discontinuity Design: Simulation and Application in Two Cardiovascular Trials with Continuous Outcomes.

Epidemiology 2016 07;27(4):503-11

From the aCentre for Medical Decision Making, Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands; bDepartment of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, The Netherlands; cInstitute for Evidence-Based Medicine in Old Age, Leiden, The Netherlands; dDepartment of Neurology, Academic Medical Center, Amsterdam, The Netherlands; and eDepartment of Neurology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/EDE.0000000000000486DOI Listing
July 2016

High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk.

Eur J Prev Cardiol 2016 09 16;23(13):1383-92. Epub 2016 Feb 16.

Department of Gerontology and Geriatrics, Leiden University Medical Center, the Netherlands Institute for Evidence-Based Medicine in Old Age, the Netherlands.

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http://dx.doi.org/10.1177/2047487316632364DOI Listing
September 2016

Predicting mortality in acutely hospitalized older patients: a retrospective cohort study.

Intern Emerg Med 2016 Jun 29;11(4):587-94. Epub 2016 Jan 29.

Department of Gerontology and Geriatrics, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s11739-015-1381-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853459PMC
June 2016

Physician's Prescribing Preference as an Instrumental Variable: Exploring Assumptions Using Survey Data.

Epidemiology 2016 Mar;27(2):276-83

From the aDepartment of Clinical Epidemiology, bDepartment of Medical Statistics and Bioinformatics, cDepartment of Endocrinology and Metabolic Diseases, Leiden University Medical Centre, Leiden, The Netherlands; dDepartment of Clinical Epidemiology, Aarhus Medical Centre, Aarhus, Denmark; eBern Institute of General Practice, University of Bern, Bern, Switzerland; fDepartment of Epidemiology and Public Health, University College Cork, Cork, Ireland; gDepartment of General Practice and Primary Health Care, University of Auckland, Auckland, New Zealand; hArthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire, United Kingdom; iInstitute for Evidence-based Medicine in Old age (IEMO), Leiden, The Netherlands; jDepartment of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, The Netherlands; kInstitute of General Practice, Johann Wolfgang Goethe University, Frankfurt, Germany; lDepartment of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland; mInstitute of General Practice and Health Services Research, University of Zürich, Zürich, Switzerland; nDepartment of Primary and Community Care, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands; oDepartment of Internal Medicine, University Hospital of Zürich, Zürich, Switzerland; pDepartment of Public Health and Primary Care, Leiden University Medical Centre, Leiden, The Netherlands; and qResearch department of Primary Care and Population health, University College London, United Kingdom.

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http://dx.doi.org/10.1097/EDE.0000000000000425DOI Listing
March 2016

Resting heart rate, heart rate variability and functional decline in old age.

CMAJ 2015 Oct 31;187(15):E442-E449. Epub 2015 Aug 31.

Department of Gerontology and Geriatrics (Ogliari, Mahinrad, Mooijaart, Westendorp, de Craen, Sabayan), Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Sciences and Community Health (Ogliari), University of Milan, Milan, Italy; Academic Section of Geriatric Medicine (Stott), Faculty of Medicine, University of Glasgow, Glasgow, United Kingdom; Department of Cardiology (Jukema), Leiden University Medical Center, Leiden, the Netherlands; Institute for Evidence-Based Medicine in Old Age (Mooijaart), Leiden, the Netherlands; Institute of Cardiovascular and Medical Sciences (Macfarlane, Clark), University of Glasgow, Glasgow, United Kingdom; Department of Epidemiology and Public Health (Kearney), University College Cork, Cork, Ireland; Department of Public Health (Westendorp), University of Copenhagen, Copenhagen, Denmark; Department of Radiology (Sabayan), Leiden University Medical Center, Leiden, the Netherlands

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http://dx.doi.org/10.1503/cmaj.150462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610849PMC
October 2015

Executive function, but not memory, associates with incident coronary heart disease and stroke.

Neurology 2015 Sep 5;85(9):783-9. Epub 2015 Aug 5.

From the Departments of Radiology (S.R., M.A.v.B., B.S.), Gerontology and Geriatrics (S.R., R.G.J.W., S.P.M., B.S., A.J.M.d.C.), and Cardiology (J.W.J.), Leiden University Medical Center, the Netherlands; and the Department of Public Health (R.G.J.W.), Copenhagen University, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000001895DOI Listing
September 2015

Blood Pressure Lowering Medication, Visit-to-Visit Blood Pressure Variability, and Cognitive Function in Old Age.

Am J Hypertens 2016 Mar 8;29(3):311-8. Epub 2015 Jul 8.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; Institute for Evidence-Based Medicine in Old age, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/ajh/hpv101DOI Listing
March 2016

Characteristics of randomized controlled trials designed for elderly: a systematic review.

PLoS One 2015 15;10(5):e0126709. Epub 2015 May 15.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands; Institute for Evidence-Based Medicine in Old Age, IEMO, Leiden, Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126709PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433127PMC
April 2016

Low thyroid function and anemia in old age: the Leiden 85-plus study.

J Am Geriatr Soc 2015 Feb;63(2):407-9

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/jgs.13282DOI Listing
February 2015

New genetic loci link adipose and insulin biology to body fat distribution.

Authors:
Dmitry Shungin Thomas W Winkler Damien C Croteau-Chonka Teresa Ferreira Adam E Locke Reedik Mägi Rona J Strawbridge Tune H Pers Krista Fischer Anne E Justice Tsegaselassie Workalemahu Joseph M W Wu Martin L Buchkovich Nancy L Heard-Costa Tamara S Roman Alexander W Drong Ci Song Stefan Gustafsson Felix R Day Tonu Esko Tove Fall Zoltán Kutalik Jian'an Luan Joshua C Randall André Scherag Sailaja Vedantam Andrew R Wood Jin Chen Rudolf Fehrmann Juha Karjalainen Bratati Kahali Ching-Ti Liu Ellen M Schmidt Devin Absher Najaf Amin Denise Anderson Marian Beekman Jennifer L Bragg-Gresham Steven Buyske Ayse Demirkan Georg B Ehret Mary F Feitosa Anuj Goel Anne U Jackson Toby Johnson Marcus E Kleber Kati Kristiansson Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Cameron D Palmer Dorota Pasko Sonali Pechlivanis Marjolein J Peters Inga Prokopenko Alena Stančáková Yun Ju Sung Toshiko Tanaka Alexander Teumer Jana V Van Vliet-Ostaptchouk Loïc Yengo Weihua Zhang Eva Albrecht Johan Ärnlöv Gillian M Arscott Stefania Bandinelli Amy Barrett Claire Bellis Amanda J Bennett Christian Berne Matthias Blüher Stefan Böhringer Fabrice Bonnet Yvonne Böttcher Marcel Bruinenberg Delia B Carba Ida H Caspersen Robert Clarke E Warwick Daw Joris Deelen Ewa Deelman Graciela Delgado Alex Sf Doney Niina Eklund Michael R Erdos Karol Estrada Elodie Eury Nele Friedrich Melissa E Garcia Vilmantas Giedraitis Bruna Gigante Alan S Go Alain Golay Harald Grallert Tanja B Grammer Jürgen Gräßler Jagvir Grewal Christopher J Groves Toomas Haller Goran Hallmans Catharina A Hartman Maija Hassinen Caroline Hayward Kauko Heikkilä Karl-Heinz Herzig Quinta Helmer Hans L Hillege Oddgeir Holmen Steven C Hunt Aaron Isaacs Till Ittermann Alan L James Ingegerd Johansson Thorhildur Juliusdottir Ioanna-Panagiota Kalafati Leena Kinnunen Wolfgang Koenig Ishminder K Kooner Wolfgang Kratzer Claudia Lamina Karin Leander Nanette R Lee Peter Lichtner Lars Lind Jaana Lindström Stéphane Lobbens Mattias Lorentzon François Mach Patrik Ke Magnusson Anubha Mahajan Wendy L McArdle Cristina Menni Sigrun Merger Evelin Mihailov Lili Milani Rebecca Mills Alireza Moayyeri Keri L Monda Simon P Mooijaart Thomas W Mühleisen Antonella Mulas Gabriele Müller Martina Müller-Nurasyid Ramaiah Nagaraja Michael A Nalls Narisu Narisu Nicola Glorioso Ilja M Nolte Matthias Olden Nigel W Rayner Frida Renstrom Janina S Ried Neil R Robertson Lynda M Rose Serena Sanna Hubert Scharnagl Salome Scholtens Bengt Sennblad Thomas Seufferlein Colleen M Sitlani Albert Vernon Smith Kathleen Stirrups Heather M Stringham Johan Sundström Morris A Swertz Amy J Swift Ann-Christine Syvänen Bamidele O Tayo Barbara Thorand Gudmar Thorleifsson Andreas Tomaschitz Chiara Troffa Floor Va van Oort Niek Verweij Judith M Vonk Lindsay L Waite Roman Wennauer Tom Wilsgaard Mary K Wojczynski Andrew Wong Qunyuan Zhang Jing Hua Zhao Eoin P Brennan Murim Choi Per Eriksson Lasse Folkersen Anders Franco-Cereceda Ali G Gharavi Åsa K Hedman Marie-France Hivert Jinyan Huang Stavroula Kanoni Fredrik Karpe Sarah Keildson Krzysztof Kiryluk Liming Liang Richard P Lifton Baoshan Ma Amy J McKnight Ruth McPherson Andres Metspalu Josine L Min Miriam F Moffatt Grant W Montgomery Joanne M Murabito George Nicholson Dale R Nyholt Christian Olsson John Rb Perry Eva Reinmaa Rany M Salem Niina Sandholm Eric E Schadt Robert A Scott Lisette Stolk Edgar E Vallejo Harm-Jan Westra Krina T Zondervan Philippe Amouyel Dominique Arveiler Stephan Jl Bakker John Beilby Richard N Bergman John Blangero Morris J Brown Michel Burnier Harry Campbell Aravinda Chakravarti Peter S Chines Simone Claudi-Boehm Francis S Collins Dana C Crawford John Danesh Ulf de Faire Eco Jc de Geus Marcus Dörr Raimund Erbel Johan G Eriksson Martin Farrall Ele Ferrannini Jean Ferrières Nita G Forouhi Terrence Forrester Oscar H Franco Ron T Gansevoort Christian Gieger Vilmundur Gudnason Christopher A Haiman Tamara B Harris Andrew T Hattersley Markku Heliövaara Andrew A Hicks Aroon D Hingorani 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Frayling Leif C Groop David J Hunter Robert C Kaplan Jeffrey R O'Connell Lu Qi David Schlessinger David P Strachan Unnur Thorsteinsdottir Cornelia M van Duijn Cristen J Willer Peter M Visscher Jian Yang Joel N Hirschhorn M Carola Zillikens Mark I McCarthy Elizabeth K Speliotes Kari E North Caroline S Fox Inês Barroso Paul W Franks Erik Ingelsson Iris M Heid Ruth Jf Loos L Adrienne Cupples Andrew P Morris Cecilia M Lindgren Karen L Mohlke

Nature 2015 Feb;518(7538):187-196

Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.

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February 2015

Biological correlates of blood pressure variability in elderly at high risk of cardiovascular disease.

Am J Hypertens 2015 Apr 8;28(4):469-79. Epub 2014 Oct 8.

Academic Section of Geriatric Medicine, University of Glasgow-Faculty of Medicine, Glasgow Royal Infirmary, Glasgow, UK.

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April 2015

NT-proBNP, blood pressure, and cognitive decline in the oldest old: The Leiden 85-plus Study.

Neurology 2014 Sep 20;83(13):1192-9. Epub 2014 Aug 20.

From the Departments of Gerontology and Geriatrics (P.v.V., B.S., L.W.W., S.P.M., A.J.M.d.C., R.G.J.W.), Neurology (P.v.V.), Radiology (B.S.), and Public Health and Primary Care (R.K.E.P., W.d.R., J.G.), Leiden University Medical Center; and Netherlands Consortium of Healthy Ageing (L.W.W., A.J.M.d.C., R.G.J.W.), Leiden, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176025PMC
September 2014

Letter regarding the Paper by Pearce et al. Entitled '2013 ETA Guideline: Management of Subclinical Hypothyroidism'.

Eur Thyroid J 2014 Jun 9;3(2):141-2. Epub 2014 May 9.

Institute for Evidence-Based Medicine in Old Age/IEMO, Leiden, The Netherlands ; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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June 2014

N-terminal pro-brain natriuretic peptide and cognitive decline in older adults at high cardiovascular risk.

Ann Neurol 2014 Aug 9;76(2):213-22. Epub 2014 Jul 9.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands; Netherlands Consortium for Healthy Ageing, Leiden, the Netherlands.

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August 2014

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Hum Mol Genet 2014 Aug 31;23(16):4420-32. Epub 2014 Mar 31.

Department of Molecular Epidemiology, Netherlands Consortium for Healthy Ageing,

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August 2014

Association of liver enzymes and computed tomography markers of liver steatosis with familial longevity.

PLoS One 2014 14;9(3):e91085. Epub 2014 Mar 14.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands; Netherlands Consortium for Healthy Ageing, Leiden, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954617PMC
December 2014

Renal function in familial longevity: the Leiden Longevity Study.

Exp Gerontol 2014 Mar 2;51:65-70. Epub 2014 Jan 2.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; Netherlands Consortium for Healthy Ageing, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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March 2014

Ambulant 24-h glucose rhythms mark calendar and biological age in apparently healthy individuals.

Aging Cell 2013 Apr 6;12(2):207-13. Epub 2013 Feb 6.

Department of Gerontology and Geriatrics, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

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April 2013

Low blood pressure predicts increased mortality in very old age even without heart failure: the Leiden 85-plus Study.

Eur J Heart Fail 2013 May 17;15(5):528-33. Epub 2012 Dec 17.

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.

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May 2013

[Should subclinical hypothyroidism in older persons be treated?].

Ned Tijdschr Geneeskd 2012 ;156(49):A5094

Leids Universitair Medisch Centrum, afd. Public Health en Eerstelijnsgeneeskunde, Leiden, the Netherlands.

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January 2013