Simon P Harding

Simon P Harding

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Ophthalmology 2019 Sep;126(9):e72-e73

Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2019.04.026DOI Listing
September 2019

Effects of Topically Administered Neuroprotective Drugs in Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial.

Diabetes 2019 02 2;68(2):457-463. Epub 2018 Nov 2.

Association for Innovation and Biomedical Research on Light and Image (AIBILI), Coimbra, Portugal, and Faculty of Medicine, University of Coimbra, Ophthalmology Department, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db18
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http://dx.doi.org/10.2337/db18-0682DOI Listing
February 2019

Intralesional Macular Atrophy in Anti-Vascular Endothelial Growth Factor Therapy for Age-Related Macular Degeneration in the IVAN Trial.

Ophthalmology 2019 Jan 6;126(1):75-86. Epub 2018 Oct 6.

Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01616420173384
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http://dx.doi.org/10.1016/j.ophtha.2018.07.013DOI Listing
January 2019

Spatial statistical modelling of capillary non-perfusion in the retina.

Sci Rep 2017 12 1;7(1):16792. Epub 2017 Dec 1.

Department of Eye & Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, 6 West Derby Street, Liverpool, L7 8TX, United Kingdom.

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http://dx.doi.org/10.1038/s41598-017-16620-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711887PMC
December 2017

Deformation velocity imaging using optical coherence tomography and its applications to the cornea.

Biomed Opt Express 2017 Dec 13;8(12):5579-5593. Epub 2017 Nov 13.

Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, L7 8TX, UK.

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http://dx.doi.org/10.1364/BOE.8.005579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745104PMC
December 2017

Individualised variable-interval risk-based screening for sight-threatening diabetic retinopathy: the Liverpool Risk Calculation Engine.

Diabetologia 2017 Nov 24;60(11):2174-2182. Epub 2017 Aug 24.

Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, William Henry Duncan Building, 6, West Derby Street, Liverpool, L7 8TX, UK.

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http://dx.doi.org/10.1007/s00125-017-4386-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448900PMC
November 2017

Longitudinal Visuomotor Development in a Malaria Endemic Area: Cerebral Malaria and Beyond.

PLoS One 2016 20;11(10):e0164885. Epub 2016 Oct 20.

Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, William Duncan Building, Liverpool, L7 ATX, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164885PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072745PMC
June 2017

Safety of lumbar puncture in comatose children with clinical features of cerebral malaria.

Neurology 2016 Nov 28;87(22):2355-2362. Epub 2016 Oct 28.

From the Institute of Infection and Global Health (C.A.M., T.S.) and Department of Eye and Vision Science, Institute of Ageing and Chronic Disease (I.J.M., N.A.B., S.P.G., S.P.H.), University of Liverpool (S.P.H.), UK; Departments of Epidemiology and Biostatistics (L.Z., C.L.) and Osteopathic Medical Specialties (K.B.S.) and International Neurology and Psychiatry Epidemiology Program (D.G.P.), Michigan State University, East Lansing; Lancaster University (P.J.D.), UK; Department of Paediatrics and Child Health (M.M.) and the Blantyre Malaria Project (T.E.T.), University of Malawi College of Medicine, Blantyre; St. Paul's Eye Unit (N.A.B.), Royal Liverpool University Hospital; School of Medicine (S.J.G.), University of St. Andrews, UK; Kilimanjaro Centre for Community Ophthalmology (KCCO) (S.L.), University of Cape Town, Department of Ophthalmology, OMB Groote Schuur Hospital Observatory, South Africa; Department of Radiology (S.K.), Queen Elizabeth Central Hospital, Blantyre, Malawi; and Department of Imaging Services (M.J.P.), University of Rochester, NY.

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http://dx.doi.org/10.1212/WNL.0000000000003372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135026PMC
November 2016

Retinal vessel segmentation: an efficient graph cut approach with retinex and local phase.

PLoS One 2015 1;10(4):e0122332. Epub 2015 Apr 1.

Department of Eye and Vision Science, University of Liverpool, Liverpool, United Kingdom; St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122332PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382050PMC
February 2016

Automated detection of leakage in fluorescein angiography images with application to malarial retinopathy.

Sci Rep 2015 Jun 1;5:10425. Epub 2015 Jun 1.

1] Department of Eye and Vision Science, University of Liverpool, Liverpool, United Kingdom [2] St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.

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http://dx.doi.org/10.1038/srep10425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450752PMC
June 2015

Automated Detection of Vessel Abnormalities on Fluorescein Angiogram in Malarial Retinopathy.

Sci Rep 2015 Jun 8;5:11154. Epub 2015 Jun 8.

1] Department of Eye and Vision Science, University of Liverpool, Liverpool, UK [2] St. Pauls Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.

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http://www.nature.com/articles/srep11154
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http://dx.doi.org/10.1038/srep11154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459173PMC
June 2015

Standardization of choroidal thickness measurements using enhanced depth imaging optical coherence tomography.

Int J Ophthalmol 2015 18;8(3):484-91. Epub 2015 Jun 18.

Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool L69 3GA, United Kingdom ; St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool L7 8XP, United Kingdom.

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http://dx.doi.org/10.3980/j.issn.2222-3959.2015.03.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458650PMC
June 2015

A comprehensive texture segmentation framework for segmentation of capillary non-perfusion regions in fundus fluorescein angiograms.

PLoS One 2014 18;9(4):e93624. Epub 2014 Apr 18.

Department of Eye and Vision Science, University of Liverpool, Liverpool, United Kingdom; St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093624PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991579PMC
January 2015

Reply: Retinopathy, histidine-rich protein-2 and perfusion pressure in cerebral malaria.

Brain 2014 Sep 11;137(Pt 9):e299. Epub 2014 Jun 11.

2 Department of Eye and Vision Science, University of Liverpool, UK3 St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.

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http://dx.doi.org/10.1093/brain/awu146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132643PMC
September 2014

Cerebral malaria in children: using the retina to study the brain.

Brain 2014 Aug 26;137(Pt 8):2119-42. Epub 2014 Feb 26.

2 University of Liverpool, Department of Eye and Vision Science, Faculty of Health & Life Sciences, University of Liverpool Room 356, 4th Floor, UCD Building, Daulby Street, Liverpool L69 3GA, UK3 Royal Liverpool University Hospital, St. Paul's Eye Unit, Prescot St, Liverpool, Merseyside L7 8XP, UK.

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http://dx.doi.org/10.1093/brain/awu001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107732PMC
August 2014

Seven new loci associated with age-related macular degeneration.

Authors:
Lars G Fritsche Wei Chen Matthew Schu Brian L Yaspan Yi Yu Gudmar Thorleifsson Donald J Zack Satoshi Arakawa Valentina Cipriani Stephan Ripke Robert P Igo Gabriëlle H S Buitendijk Xueling Sim Daniel E Weeks Robyn H Guymer Joanna E Merriam Peter J Francis Gregory Hannum Anita Agarwal Ana Maria Armbrecht Isabelle Audo Tin Aung Gaetano R Barile Mustapha Benchaboune Alan C Bird Paul N Bishop Kari E Branham Matthew Brooks Alexander J Brucker William H Cade Melinda S Cain Peter A Campochiaro Chi-Chao Chan Ching-Yu Cheng Emily Y Chew Kimberly A Chin Itay Chowers David G Clayton Radu Cojocaru Yvette P Conley Belinda K Cornes Mark J Daly Baljean Dhillon Albert O Edwards Evangelos Evangelou Jesen Fagerness Henry A Ferreyra James S Friedman Asbjorg Geirsdottir Ronnie J George Christian Gieger Neel Gupta Stephanie A Hagstrom Simon P Harding Christos Haritoglou John R Heckenlively Frank G Holz Guy Hughes John P A Ioannidis Tatsuro Ishibashi Peronne Joseph Gyungah Jun Yoichiro Kamatani Nicholas Katsanis Claudia N Keilhauer Jane C Khan Ivana K Kim Yutaka Kiyohara Barbara E K Klein Ronald Klein Jaclyn L Kovach Igor Kozak Clara J Lee Kristine E Lee Peter Lichtner Andrew J Lotery Thomas Meitinger Paul Mitchell Saddek Mohand-Saïd Anthony T Moore Denise J Morgan Margaux A Morrison Chelsea E Myers Adam C Naj Yusuke Nakamura Yukinori Okada Anton Orlin M Carolina Ortube Mohammad I Othman Chris Pappas Kyu Hyung Park Gayle J T Pauer Neal S Peachey Olivier Poch Rinki Ratna Priya Robyn Reynolds Andrea J Richardson Raymond Ripp Guenther Rudolph Euijung Ryu José-Alain Sahel Debra A Schaumberg Hendrik P N Scholl Stephen G Schwartz William K Scott Humma Shahid Haraldur Sigurdsson Giuliana Silvestri Theru A Sivakumaran R Theodore Smith Lucia Sobrin Eric H Souied Dwight E Stambolian Hreinn Stefansson Gwen M Sturgill-Short Atsushi Takahashi Nirubol Tosakulwong Barbara J Truitt Evangelia E Tsironi André G Uitterlinden Cornelia M van Duijn Lingam Vijaya Johannes R Vingerling Eranga N Vithana Andrew R Webster H-Erich Wichmann Thomas W Winkler Tien Y Wong Alan F Wright Diana Zelenika Ming Zhang Ling Zhao Kang Zhang Michael L Klein Gregory S Hageman G Mark Lathrop Kari Stefansson Rando Allikmets Paul N Baird Michael B Gorin Jie Jin Wang Caroline C W Klaver Johanna M Seddon Margaret A Pericak-Vance Sudha K Iyengar John R W Yates Anand Swaroop Bernhard H F Weber Michiaki Kubo Margaret M Deangelis Thierry Léveillard Unnur Thorsteinsdottir Jonathan L Haines Lindsay A Farrer Iris M Heid Gonçalo R Abecasis

Nat Genet 2013 Apr 3;45(4):433-9, 439e1-2. Epub 2013 Mar 3.

Institute of Human Genetics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.2578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739472PMC
April 2013

Computerized assessment of intraretinal and subretinal fluid regions in spectral-domain optical coherence tomography images of the retina.

Am J Ophthalmol 2013 Feb 27;155(2):277-286.e1. Epub 2012 Oct 27.

Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S00029394120055
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http://dx.doi.org/10.1016/j.ajo.2012.07.030DOI Listing
February 2013

Prevalence of raised intracranial pressure in cerebral malaria detected by optic nerve sheath ultrasound.

Am J Trop Med Hyg 2012 Dec 1;87(6):985-8. Epub 2012 Oct 1.

St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.

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http://dx.doi.org/10.4269/ajtmh.2012.11-0459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516101PMC
December 2012

Ranibizumab versus bevacizumab to treat neovascular age-related macular degeneration: one-year findings from the IVAN randomized trial.

Ophthalmology 2012 Jul 11;119(7):1399-411. Epub 2012 May 11.

Institute of Clinical Science, The Queen's University of Belfast, Belfast, Ireland.

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http://dx.doi.org/10.1016/j.ophtha.2012.04.015DOI Listing
July 2012

Age-related macular degeneration: the importance of family history as a risk factor.

Br J Ophthalmol 2012 Mar 23;96(3):427-31. Epub 2011 Aug 23.

Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1136/bjophthalmol-2011-300193DOI Listing
March 2012

Prevalence of diabetic retinopathy, cataract and visual impairment in patients with diabetes in sub-Saharan Africa.

Br J Ophthalmol 2012 Feb 21;96(2):156-61. Epub 2011 Apr 21.

Ophthalmology Research Unit, University of Liverpool, Royal Liverpool University Hospital, Liverpool L7 8XP, UK.

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http://dx.doi.org/10.1136/bjo.2010.196071DOI Listing
February 2012

Early multifocal electroretinogram findings during intravitreal ranibizumab treatment for neovascular age-related macular degeneration.

Invest Ophthalmol Vis Sci 2011 Jun 1;52(6):3446-51. Epub 2011 Jun 1.

Department of Eye and Vision Sciences, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1167/iovs.10-6588DOI Listing
June 2011

Automated segmentation of foveal avascular zone in fundus fluorescein angiography.

Invest Ophthalmol Vis Sci 2010 Jul 3;51(7):3653-9. Epub 2010 Feb 3.

Ophthalmology Research Unit, School of Clinical Sciences, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1167/iovs.09-4935DOI Listing
July 2010

Perfusion abnormalities in children with cerebral malaria and malarial retinopathy.

J Infect Dis 2009 Jan;199(2):263-71

St. Paul's Eye Unit, Royal Liverpool University Hospital, Prescot Street, Liverpool, United Kingdom.

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http://dx.doi.org/10.1086/595735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757304PMC
January 2009

New classification of acute papilledema in children with severe malaria.

J Pediatr Neurol 2009 ;7(4):381-388

St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.

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http://dx.doi.org/10.3233/JPN-2009-0317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672988PMC
January 2009

Using malarial retinopathy to improve the classification of children with cerebral malaria.

Trans R Soc Trop Med Hyg 2008 Nov 28;102(11):1089-94. Epub 2008 Aug 28.

Kilimanjaro Centre for Community Ophthalmology, Tumaini University/KCMC, Moshi, Tanzania.

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http://dx.doi.org/10.1016/j.trstmh.2008.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804549PMC
November 2008

Multifocal electroretinography as a predictor of maintenance of vision after photodynamic therapy for neovascular age-related macular degeneration.

Doc Ophthalmol 2008 Jan 21;116(1):13-8. Epub 2007 Sep 21.

Department of Clinical Engineering, Royal Liverpool University Hospital, Liverpool, UK.

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http://dx.doi.org/10.1007/s10633-007-9071-zDOI Listing
January 2008

Deficits in the electroretinogram in neovascular age-related macular degeneration and changes during photodynamic therapy.

Doc Ophthalmol 2007 Sep 2;115(2):69-76. Epub 2007 Aug 2.

Department of Clinical Engineering, Royal Liverpool University Hospital, Prescot Street, Liverpool, UK.

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http://dx.doi.org/10.1007/s10633-007-9056-yDOI Listing
September 2007

Malarial retinopathy: a newly established diagnostic sign in severe malaria.

Am J Trop Med Hyg 2006 Nov;75(5):790-7

Malawi-Liverpool-Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367432PMC
November 2006

Mycophenolate mofetil as an immunosuppressive agent in refractory inflammatory eye disease.

J Ocul Pharmacol Ther 2006 Jun;22(3):168-75

St. Paul's Eye Unit, Royal Liverpool and Broadgreen University Hospital, Liverpool, UK.

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http://dx.doi.org/10.1089/jop.2006.22.168DOI Listing
June 2006

Prognostic significance and course of retinopathy in children with severe malaria.

Arch Ophthalmol 2004 Aug;122(8):1141-7

St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, England.

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http://dx.doi.org/10.1001/archopht.122.8.1141DOI Listing
August 2004

Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic Eye Study: a cohort study.

Lancet 2003 Jan;361(9353):195-200

Department of Diabetes and Endocrinology, Royal Liverpool University Hospital, UK.

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http://dx.doi.org/10.1016/s0140-6736(03)12267-2DOI Listing
January 2003