Publications by authors named "Simon Low"

9Publications

A Functional Na1.7-NaAb Chimera with a Reconstituted High-Affinity ProTx-II Binding Site.

Mol Pharmacol 2017 09 23;92(3):310-317. Epub 2017 Jun 23.

Molecular Discovery Technologies, Wallingford, Connecticut, Princeton, New Jersey, and Waltham, Massachusetts (R.R., S.W., I.R., M.G., S.L., L.M., D.W., D.R.L.); Discovery Biology (R.L.P., D.J.P.-M., M.K.A., L.J.B., J.H.) and Lead Discovery and Optimization (J.W.), Bristol-Myers Squibb Company, Wallingford, Connecticut.

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http://dx.doi.org/10.1124/mol.117.108712DOI Listing
September 2017

Pharmacologic profile of the Adnectin BMS-962476, a small protein biologic alternative to PCSK9 antibodies for low-density lipoprotein lowering.

J Pharmacol Exp Ther 2014 Aug 10;350(2):412-24. Epub 2014 Jun 10.

Molecular Discovery Technologies (T.M., G.C., D.S., S.L., K.R., R.D., F.D., M.G., J.M., G.D., M.W., J.K.), Applied Genomics (S.P.H.), and Cardiovascular Discovery Biology (F.L., H.M., D.M., B.M., R.A.P.), Bristol-Myers Squibb Research and Development, Princeton, New Jersey.

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http://jpet.aspetjournals.org/content/350/2/412.full.pdf
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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.114.21422
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http://dx.doi.org/10.1124/jpet.114.214221DOI Listing
August 2014

Identifying factors associated with performance in a mock CSA: perceptions from trainees and trainers from one deanery.

Educ Prim Care 2013 Sep;24(6):452-60

General Practitioner Principal, Hampshire, UK.

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http://dx.doi.org/10.1080/14739879.2013.11494216DOI Listing
September 2013

Enhanced selectivity profile of pyrazole-urea based DFG-out p38alpha inhibitors.

Bioorg Med Chem Lett 2010 Aug 17;20(16):4885-91. Epub 2010 Jun 17.

Department of Chemistry, Cambridge South Laboratories, Pfizer Inc., 620 Memorial Drive, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.bmcl.2010.06.073DOI Listing
August 2010

Selectivity-determining residues in Plk1.

Chem Biol Drug Des 2007 Dec 13;70(6):540-6. Epub 2007 Nov 13.

Pfizer Global Research and Development, Research Technology Center, 620 Memorial Drive, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1111/j.1747-0285.2007.00594.xDOI Listing
December 2007

Structure of the catalytic domain of human polo-like kinase 1.

Biochemistry 2007 May 27;46(20):5960-71. Epub 2007 Apr 27.

Pfizer Global Research and Development, Research Technology Center, 620 Memorial Drive, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1021/bi602474jDOI Listing
May 2007

Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system.

Biochemistry 2005 Jun;44(23):8312-25

Department of Biology, Pfizer Research Technology Center, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1021/bi047313hDOI Listing
June 2005