Simon J Heeringen

Simon J van Heeringen

UNVERIFIED PROFILE

Are you Simon J van Heeringen?   Register this Author

Register author
Simon J Heeringen

Simon J van Heeringen

Publications by authors named "Simon J van Heeringen"

38Publications

777Reads

46Profile Views

1PubMed Central Citations

Single-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome.

Proc Natl Acad Sci U S A 2019 Aug 14;116(35):17361-17370. Epub 2019 Aug 14.

Department of Molecular Developmental Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, 6525GA Nijmegen, The Netherlands;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1908180116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717277PMC
August 2019

WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming.

Stem Cell Reports 2019 Apr 14;12(4):743-756. Epub 2019 Mar 14.

Department of Molecular Developmental Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen 6500 HB, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2019.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449870PMC
April 2019

Splicing and Chromatin Factors Jointly Regulate Epidermal Differentiation.

Cell Rep 2018 Oct;25(5):1292-1303.e5

Faculty of Science, Radboud University, Nijmegen, the Netherlands; Department of Molecular Developmental Biology, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22111247183158
Publisher Site
http://dx.doi.org/10.1016/j.celrep.2018.10.017DOI Listing
October 2018

MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding.

Nat Genet 2018 07 28;50(7):1002-1010. Epub 2018 May 28.

Department of Molecular Developmental Biology, Radboud University, Faculty of Science, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41588-018-0134-8
Publisher Site
http://dx.doi.org/10.1038/s41588-018-0134-8DOI Listing
July 2018

Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions DC-SCRIPT and Dual-Specificity Phosphatase 4.

Front Immunol 2018 22;9:1420. Epub 2018 Jun 22.

Radiotherapy & OncoImmunology Laboratory, Department of Radiation Oncology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2018.01420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023963PMC
June 2018

ChIP-seq Data Processing for PcG Proteins and Associated Histone Modifications.

Methods Mol Biol 2016 ;1480:37-53

Radboud University, Department of Molecular Developmental Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Nijmegen, 6500HB, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-6380-5_4DOI Listing
January 2018

Regulatory remodeling in the allo-tetraploid frog Xenopus laevis.

Genome Biol 2017 10 24;18(1):198. Epub 2017 Oct 24.

Radboud University, Faculty of Science, Department of Molecular Developmental Biology, Radboud Institute for Molecular Life Sciences, 6500 HB, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-017-1335-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655803PMC
October 2017

Heterochromatic histone modifications at transposons in Xenopus tropicalis embryos.

Dev Biol 2017 06 14;426(2):460-471. Epub 2016 Sep 14.

Radboud University, Department of Molecular Developmental Biology, Radboud Institute for Molecular Life Sciences, Faculty of Science, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ydbio.2016.08.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350053PMC
June 2017

Genomic organization and modulation of gene expression of the TGF-β and FGF pathways in the allotetraploid frog Xenopus laevis.

Dev Biol 2017 06 28;426(2):336-359. Epub 2016 Sep 28.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ydbio.2016.09.016DOI Listing
June 2017

Genome evolution in the allotetraploid frog Xenopus laevis.

Nature 2016 10;538(7625):336-343

University of California, Berkeley, Department of Molecular and Cell Biology and Center for Integrative Genomics, Life Sciences Addition #3200, Berkeley, California 94720-3200, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature19840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313049PMC
October 2016

fluff: exploratory analysis and visualization of high-throughput sequencing data.

PeerJ 2016 19;4:e2209. Epub 2016 Jul 19.

Radboud University, Molecular Developmental Biology , Nijmegen , The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7717/peerj.2209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957989PMC
August 2016

Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2.

Sci Rep 2016 05 5;6:24658. Epub 2016 May 5.

Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep24658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857124PMC
May 2016

Embryonic transcription is controlled by maternally defined chromatin state.

Nat Commun 2015 Dec 18;6:10148. Epub 2015 Dec 18.

Department of Molecular Developmental Biology, Radboud Institute for Molecular Life Sciences, Faculty of Science, Radboud University, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms10148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703837PMC
December 2015

Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation.

EMBO Rep 2015 Jul 1;16(7):863-78. Epub 2015 Jun 1.

Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands Department of Molecular Developmental Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences Radboud University, Nijmegen, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embr.201439941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515125PMC
July 2015

Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs.

Nucleic Acids Res 2014 Sep 23;42(15):9880-91. Epub 2014 Jul 23.

Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands Cancer Genomics Netherlands, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands

View Article

Download full-text PDF

Source
https://www.devcom-itn.eu/uploaded/Publucations/Nucl.%20Acid
Web Search
http://nar.oxfordjournals.org/content/early/2014/07/22/nar.g
Web Search
http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gku661
Publisher Site
http://dx.doi.org/10.1093/nar/gku661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150773PMC
September 2014

Principles of nucleation of H3K27 methylation during embryonic development.

Genome Res 2014 Mar 11;24(3):401-10. Epub 2013 Dec 11.

Radboud University Nijmegen, Department of Molecular Developmental Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen 6500 HB, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.159608.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941105PMC
March 2014

A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development.

BMC Genomics 2013 Nov 6;14:762. Epub 2013 Nov 6.

Radboud University Nijmegen, Dept, of Molecular Developmental Biology, Faculty of Science, Nijmegen Center for Molecular Life Sciences, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-14-762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907017PMC
November 2013

The epigenome in early vertebrate development.

Genesis 2012 Mar 27;50(3):192-206. Epub 2011 Dec 27.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre of Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dvg.20831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294079PMC
March 2012

Crosstalk between c-Jun and TAp73alpha/beta contributes to the apoptosis-survival balance.

Nucleic Acids Res 2011 Aug 31;39(14):6069-85. Epub 2011 Mar 31.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkr028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152320PMC
August 2011

Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis.

Genome Res 2011 Aug 2;21(8):1313-27. Epub 2011 Jun 2.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, 6500 Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.114843.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149498PMC
August 2011

Nucleotide composition-linked divergence of vertebrate core promoter architecture.

Genome Res 2011 Mar 10;21(3):410-21. Epub 2011 Jan 10.

Radboud University Nijmegen, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.111724.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044855PMC
March 2011

Role of p53 serine 46 in p53 target gene regulation.

PLoS One 2011 Mar 4;6(3):e17574. Epub 2011 Mar 4.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
https://core.ac.uk/download/pdf/14522541.pdf
Web Search
http://dx.plos.org/10.1371/journal.pone.0017574
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017574PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048874PMC
March 2011

GimmeMotifs: a de novo motif prediction pipeline for ChIP-sequencing experiments.

Bioinformatics 2011 Jan 15;27(2):270-1. Epub 2010 Nov 15.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
https://academic.oup.com/bioinformatics/article-lookup/doi/1
Publisher Site
http://dx.doi.org/10.1093/bioinformatics/btq636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018809PMC
January 2011

A hierarchy of H3K4me3 and H3K27me3 acquisition in spatial gene regulation in Xenopus embryos.

Dev Cell 2009 Sep;17(3):425-34

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, 6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2009.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746918PMC
September 2009

ChIP-Seq of ERalpha and RNA polymerase II defines genes differentially responding to ligands.

EMBO J 2009 May 4;28(10):1418-28. Epub 2009 Apr 4.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emboj.2009.88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688537PMC
May 2009

The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response.

Nucleic Acids Res 2009 Feb 28;37(2):322-35. Epub 2008 Nov 28.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkn940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632907PMC
February 2009

Characterization of genome-wide p53-binding sites upon stress response.

Nucleic Acids Res 2008 Jun 12;36(11):3639-54. Epub 2008 May 12.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkn232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441782PMC
June 2008