Simon J Draper

Simon J Draper

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Simon J Draper

Simon J Draper

Publications by authors named "Simon J Draper"

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SnoopLigase peptide-peptide conjugation enables modular vaccine assembly.

Sci Rep 2019 03 15;9(1):4625. Epub 2019 Mar 15.

Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.

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http://www.nature.com/articles/s41598-019-40985-w
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http://dx.doi.org/10.1038/s41598-019-40985-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420506PMC
March 2019

Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: kinetics and longevity in absence of re-exposure.

BMC Med 2019 01 30;17(1):22. Epub 2019 Jan 30.

Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, 171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12916-019-1255-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352425PMC
January 2019

Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria.

PLoS One 2018 8;13(6):e0198371. Epub 2018 Jun 8.

West Africa Centre for Medical Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon, Ghana.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198371PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993283PMC
December 2018

Erythroferrone inhibits the induction of hepcidin by BMP6.

Blood 2018 10 10;132(14):1473-1477. Epub 2018 Aug 10.

Medical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.

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http://dx.doi.org/10.1182/blood-2018-06-857995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238155PMC
October 2018

Engineering a Rugged Nanoscaffold To Enhance Plug-and-Display Vaccination.

ACS Nano 2018 09 26;12(9):8855-8866. Epub 2018 Jul 26.

Department of Biochemistry , University of Oxford , South Parks Road , Oxford OX1 3QU , United Kingdom.

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http://dx.doi.org/10.1021/acsnano.8b02805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158681PMC
September 2018

A new site of attack for a malaria vaccine.

Nat Med 2018 04;24(4):382-383

Department of Biochemistry, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/nm.4533DOI Listing
April 2018

Role of Activins in Hepcidin Regulation during Malaria.

Infect Immun 2017 12 17;85(12). Epub 2017 Nov 17.

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

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http://dx.doi.org/10.1128/IAI.00191-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695100PMC
December 2017

Plasmodium vivax Controlled Human Malaria Infection - Progress and Prospects.

Trends Parasitol 2017 02 10;33(2):141-150. Epub 2016 Dec 10.

The Jenner Institute Laboratories, Old Road Campus Research Building, University of Oxford, Oxford, OX3 7DQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2016.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270241PMC
February 2017

One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen.

Proc Natl Acad Sci U S A 2017 01 17;114(5):998-1002. Epub 2017 Jan 17.

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel;

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http://dx.doi.org/10.1073/pnas.1616903114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293100PMC
January 2017

Germinal Center B Cell and T Follicular Helper Cell Responses to Viral Vector and Protein-in-Adjuvant Vaccines.

J Immunol 2016 08 13;197(4):1242-51. Epub 2016 Jul 13.

Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom; and

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http://dx.doi.org/10.4049/jimmunol.1502472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974488PMC
August 2016

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA.

N Engl J Med 2016 Apr 28;374(17):1635-46. Epub 2015 Jan 28.

From the Jenner Institute and Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, and the National Institute for Health Research Oxford Biomedical Research Centre, Oxford (K.E., T.R., N.V., G.B., D.W., T.L., E.B.I., R.P., C.M.T., N.J.E., G.L., J.J., M.G., A.M., M.W., I.P., N.L., R.R., F.H., C.B., K.S.-D., J.P., E.B., A.J.P., S.J.D., A.L., S.C.G., A.V.S.H.), and Viral Pseudotype Unit, Faculty of Science and Technology, University of Westminster (E.M.B., E.W.), and Virus Reference Department, Public Health Agency (D.S., R.T.), London - all in the United Kingdom; the Institute of Virology, Philipps University Marburg (S.K.F., T.S., N.B., V.K., S.B.), and German Center for Infection Research, Partner Site Giessen-Marburg-Langen (S.B.), Marburg, and Bavarian Nordic, Martinsried (A.V., P.C.) - all in Germany; GlaxoSmithKline Biologicals, Rixensart, Belgium (F.R., I.D.R., W.R.B.); ReiThera, Rome (A.N., L.S., S.C., A.F., S.D.M.), and CEINGE and the Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples (A.N.) - both in Italy; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda (N.J.S., D.A.S., O.T.M., J.E.L., R.M.S., B.S.G., R.A.K.), and the Center for Vaccine Development, University of Maryland School of Medicine, Baltimore (M.M.L.) - both in Maryland; and Keires, Basel, Switzerland (R.C.).

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http://dx.doi.org/10.1056/NEJMoa1411627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798586PMC
April 2016

Recent advances in recombinant protein-based malaria vaccines.

Vaccine 2015 Dec 11;33(52):7433-43. Epub 2015 Oct 11.

The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1016/j.vaccine.2015.09.093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687528PMC
December 2015

Toward the development of effective transmission-blocking vaccines for malaria.

Expert Rev Vaccines 2015 May 19;14(5):653-80. Epub 2015 Jan 19.

The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1586/14760584.2015.993383DOI Listing
May 2015

Recent developments in malaria vaccinology.

Adv Parasitol 2015 Apr 30;88:1-49. Epub 2015 Mar 30.

The Jenner Institute, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/bs.apar.2015.03.001DOI Listing
April 2015

Malaria Vaccines: Moving Forward After Encouraging First Steps.

Curr Trop Med Rep 2015 Mar;2(1):1-3

Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.

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http://dx.doi.org/10.1007/s40475-015-0041-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435961PMC
March 2015

Microneedle-mediated immunization of an adenovirus-based malaria vaccine enhances antigen-specific antibody immunity and reduces anti-vector responses compared to the intradermal route.

Sci Rep 2014 Aug 21;4:6154. Epub 2014 Aug 21.

1] School of Pharmacy, University College Cork, Cork, Ireland [2] Dept. of Pharmacology and Therapeutics, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1038/srep06154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139947PMC
August 2014

Utilizing poxviral vectored vaccines for antibody induction-progress and prospects.

Vaccine 2013 Sep 5;31(39):4223-30. Epub 2013 Jun 5.

The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1016/j.vaccine.2013.05.091DOI Listing
September 2013

Challenges of assessing the clinical efficacy of asexual blood-stage Plasmodium falciparum malaria vaccines.

Hum Vaccin Immunother 2013 Sep 18;9(9):1831-40. Epub 2013 Jun 18.

The Jenner Institute; University of Oxford; Oxford, UK.

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http://dx.doi.org/10.4161/hv.25383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906345PMC
September 2013

Recent advances in antibody-inducing poxviral and adenoviral vectored vaccine delivery platforms for difficult disease targets.

Expert Rev Vaccines 2013 Apr;12(4):365-78

The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1586/erv.13.11DOI Listing
April 2013

Controlled human blood stage malaria infection: current status and potential applications.

Am J Trop Med Hyg 2012 Apr;86(4):561-5

Sir William Dunn School of Pathology, University of Oxford, United Kingdom.

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http://dx.doi.org/10.4269/ajtmh.2012.11-0504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403771PMC
April 2012

Accelerating vaccine development and deployment: report of a Royal Society satellite meeting.

Philos Trans R Soc Lond B Biol Sci 2011 Oct;366(1579):2841-9

Jenner Institute, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1098/rstb.2011.0100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146780PMC
October 2011

Recombinant Viral Vaccines Expressing Merozoite Surface Protein-1 Induce Antibody- and T Cell-Mediated Multistage Protection against Malaria.

Cell Host Microbe 2011 Mar 16;9(3):252. Epub 2011 Mar 16.

The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1016/j.chom.2011.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628178PMC
March 2011

Viruses as vaccine vectors for infectious diseases and cancer.

Nat Rev Microbiol 2010 Jan;8(1):62-73

The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.

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http://dx.doi.org/10.1038/nrmicro2240DOI Listing
January 2010

Effective induction of high-titer antibodies by viral vector vaccines.

Nat Med 2008 Aug 27;14(8):819-21. Epub 2008 Jul 27.

The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK.

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http://www.nature.com/articles/nm.1850
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http://dx.doi.org/10.1038/nm.1850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822545PMC
August 2008

Anti-CD25 antibody enhancement of vaccine-induced immunogenicity: increased durable cellular immunity with reduced immunodominance.

J Immunol 2005 Dec;175(11):7264-73

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.175.11.7264DOI Listing
December 2005