Simon H S Pearce

Simon H S Pearce

UNVERIFIED PROFILE

Are you Simon H S Pearce?   Register this Author

Register author
Simon H S Pearce

Simon H S Pearce

Publications by authors named "Simon H S Pearce"

Are you Simon H S Pearce?   Register this Author

80Publications

1480Reads

42Profile Views

Thyroid Hormone Therapy for Subclinical Hypothyroidism.

JAMA 2019 02;321(8):804

Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, England.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2018.20002DOI Listing
February 2019

An unusual cause of adrenal insufficiency and bilateral adrenal masses.

Endocrinol Diabetes Metab Case Rep 2018 6;2018. Epub 2018 Jul 6.

Department of Endocrinology, Newcastle Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/EDM-18-0030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038009PMC
July 2018

Low-dose levothyroxine did not improve symptoms in asymptomatic older people with subclinical hypothyroidism.

BMJ Evid Based Med 2018 02;23(1):39-40

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/ebmed-2017-110819DOI Listing
February 2018

Thyroid hormones and cardiovascular disease.

Nat Rev Cardiol 2017 01 4;14(1):39-55. Epub 2016 Nov 4.

Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrcardio.2016.174DOI Listing
January 2017

Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study.

J Clin Endocrinol Metab 2016 11 23;101(11):4385-4394. Epub 2016 Aug 23.

Institute of Genetic Medicine (S.H.S.P., S.R.), Newcastle University, Newcastle upon Tyne NE1 3BZ, United Kingdom; Institute of Health and Society (M.E.Y., C.M.-R., A.K., J.C., T.B.K., C.J.), Newcastle University, Newcastle upon Tyne NE2 4AX, United Kingdom; and Department of Internal Medicine (T.J.V.), Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2016-1935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095241PMC
November 2016

A Variant in the BACH2 Gene Is Associated With Susceptibility to Autoimmune Addison's Disease in Humans.

J Clin Endocrinol Metab 2016 Nov 28;101(11):3865-3869. Epub 2016 Sep 28.

Institute of Genetic Medicine (A.P., C.M.N., H.F.A., H.J.C., S.H.S.P., A.L.M.), Newcastle University, Newcastle upon Tyne NE1 3BZ, United Kingdom; Department of Clinical Science (B.E.O., E.S.H.), University of Bergen, 5021 Bergen, Norway; and Department of Medicine (E.S.H.), Haukeland University Hospital, 5021 Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2016-2368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095240PMC
November 2016

Study of Optimal Replacement of Thyroxine in the Elderly (SORTED) - results from the feasibility randomised controlled trial.

Thyroid Res 2016 10;9. Epub 2016 Oct 10.

Department of Pharmacy, Health and Wellbeing, Faculty of Applied Sciences, University of Sunderland, Sunderland, SR1 3SD UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13044-016-0034-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057427PMC
October 2016

Loperamide-induced hypopituitarism.

BMJ Case Rep 2016 Sep 28;2016. Epub 2016 Sep 28.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK Department of Endocrinology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2016-216384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051368PMC
September 2016

Subclinical hyperthyroidism: first do no harm.

Clin Endocrinol (Oxf) 2016 07 20;85(1):15-6. Epub 2016 Apr 20.

Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cen.13070DOI Listing
July 2016

Spontaneous and tetracosactide-induced anti-ACTH antibodies in man.

Clin Endocrinol (Oxf) 2016 Apr 25;84(4):489-95. Epub 2015 Jun 25.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cen.12795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949547PMC
April 2016

Insufficient evidence to favour prednisolone over hydrocortisone in glucocorticoid replacement.

Authors:
Simon H S Pearce

BMJ 2014 Sep 9;349:g5510. Epub 2014 Sep 9.

University of Newcastle upon Tyne, Newcastle upon Tyne, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.g5510DOI Listing
September 2014

Diagnosis and management of thyrotoxicosis.

BMJ 2014 Aug 21;349:g5128. Epub 2014 Aug 21.

Endocrine Unit, Royal Victoria Infirmary and Newcastle University, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.g5128DOI Listing
August 2014

Current and emerging therapies for Addison's disease.

Curr Opin Endocrinol Diabetes Obes 2014 Jun;21(3):147-53

Institute of Genetic Medicine, Newcastle University, and Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MED.0000000000000067DOI Listing
June 2014

Residual adrenal function in autoimmune Addison's disease: improvement after tetracosactide (ACTH1-24) treatment.

J Clin Endocrinol Metab 2014 Jan 20;99(1):111-8. Epub 2013 Dec 20.

Institute of Genetic Medicine (E.H.G., K.M., A.L.M., P.P., R.Q., S.H.S.P.), Newcastle University, Newcastle upon Tyne NE1 3BZ, United Kingdom; the Endocrine Unit (E.H.G., A.L.M., P.P., S.G.B., R.A.J., R.Q., S.H.S.P.), Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, United Kingdom; the Centre for Endocrinology, Diabetes, and Metabolism (B.A.H., W.A.), University of Birmingham, Birmingham B15 2TT, United Kingdom; and RSR Ltd (S.C., J.F.), FIRS Laboratories, Cardiff CF4 5DU, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2013-2449DOI Listing
January 2014

2013 ETA Guideline: Management of Subclinical Hypothyroidism.

Eur Thyroid J 2013 Dec 27;2(4):215-28. Epub 2013 Nov 27.

Clinique Endocrinologique Marc Linquette, CHU, Lille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000356507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923601PMC
December 2013

A UK epidemic of testosterone prescribing, 2001-2010.

Clin Endocrinol (Oxf) 2013 Oct 5;79(4):564-70. Epub 2013 Apr 5.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/cen.12178
Publisher Site
http://dx.doi.org/10.1111/cen.12178DOI Listing
October 2013

How should I approach standard endocrine evaluation in patients with coeliac disease?

Clin Endocrinol (Oxf) 2013 Oct 9;79(4):464-7. Epub 2013 Aug 9.

Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cen.12283DOI Listing
October 2013

The effect of B cell depletion therapy on anti-TSH receptor antibodies and clinical outcome in glucocorticoid-refractory Graves' orbitopathy.

Clin Endocrinol (Oxf) 2013 Sep 11;79(3):437-42. Epub 2013 May 11.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cen.12141DOI Listing
September 2013

Prevention and treatment of vitamin D deficiency.

Calcif Tissue Int 2013 Feb 3;92(2):207-15. Epub 2012 Nov 3.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00223-012-9663-9
Publisher Site
http://dx.doi.org/10.1007/s00223-012-9663-9DOI Listing
February 2013

The role of functionally defective rare germline variants of sialic acid acetylesterase in autoimmune Addison's disease.

Eur J Endocrinol 2012 Dec 25;167(6):825-8. Epub 2012 Sep 25.

Institute of Genetic Medicine, International Centre for Life, Newcastle University, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/EJE-12-0579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494867PMC
December 2012

Autoimmune Addison's disease.

Presse Med 2012 Dec 21;41(12 P 2):e626-35. Epub 2012 Nov 21.

Newcastle-upon-Tyne Hospitals NHS trust, Royal Victoria Infirmary, Endocrine Unit, Newcastle upon Tyne, NE1 4LP, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lpm.2012.09.010DOI Listing
December 2012

Adrenal steroidogenesis after B lymphocyte depletion therapy in new-onset Addison's disease.

J Clin Endocrinol Metab 2012 Oct 5;97(10):E1927-32. Epub 2012 Jul 5.

Newcastle University, Newccastle upon Tyne Hospitals National Health Service Foundation Trust, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2012-1680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462934PMC
October 2012

Clinical review: The thyroid in mind: cognitive function and low thyrotropin in older people.

J Clin Endocrinol Metab 2012 Oct 3;97(10):3438-49. Epub 2012 Aug 3.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2012-2284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496329PMC
October 2012

Subclinical hypothyroidism and cardiovascular disease-reply.

Arch Intern Med 2012 Oct;172(19):1523-4

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/2013.jamainternmed.597DOI Listing
October 2012

Treatment for primary hypothyroidism: current approaches and future possibilities.

Drug Des Devel Ther 2012 22;6:1-11. Epub 2011 Dec 22.

Department of Endocrinology, Royal Devon and Exeter Hospital and Peninsula Medical School, Exeter, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/DDDT.S12894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267517PMC
May 2012

Management of subclinical hypothyroidism: the thyroidologists' view.

Eur Thyroid J 2012 Apr 29;1(1):45-50. Epub 2012 Feb 29.

Clinique Endocrinologique Marc Linquette, CHU, Lille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000335964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821451PMC
April 2012

Autoimmune Addison disease: pathophysiology and genetic complexity.

Nat Rev Endocrinol 2012 Jan 31;8(5):306-16. Epub 2012 Jan 31.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK. anna.mitchell@ ncl.ac.uk

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nrendo.2011.245
Publisher Site
http://dx.doi.org/10.1038/nrendo.2011.245DOI Listing
January 2012

Primary hyperparathyroidism: just how 'primary' is it really?

Ther Adv Endocrinol Metab 2010 Oct;1(5):191-6

Dr Stephen G. Ball, MD, FRCP University of Newcastle-upon-Tyne and Newcastle-upon-Tyne Hospitals Foundation NHS Trust, Newcastle-upon-Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2042018810389646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474618PMC
October 2010

Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study.

Eur J Hum Genet 2010 Sep 5;18(9):1021-6. Epub 2010 May 5.

Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, Institute of Biomedical Research, University of Birmingham, Birmingham, West Midlands, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2010.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987410PMC
September 2010

Subclinical thyroid disorders: significance and clinical impact.

J Clin Pathol 2010 May;63(5):379-86

Department of Endocrinology, Gateshead Health NHS Foundation Trust, Gateshead, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jcp.2008.057414DOI Listing
May 2010

The incidence of ischemic heart disease and mortality in people with subclinical hypothyroidism: reanalysis of the Whickham Survey cohort.

J Clin Endocrinol Metab 2010 Apr 11;95(4):1734-40. Epub 2010 Feb 11.

Department of Endocrinology, Gateshead Health National Health Service Foundation Trust, Gateshead NE9 6SX, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2009-1749DOI Listing
April 2010

How should we treat patients with low serum thyrotropin concentrations?

Clin Endocrinol (Oxf) 2010 Mar 10;72(3):292-6. Epub 2009 Sep 10.

Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2265.2009.03694.xDOI Listing
March 2010

Diagnostic challenges due to phenocopies: lessons from Multiple Endocrine Neoplasia type1 (MEN1).

Hum Mutat 2010 Jan;31(1):E1089-101

Academic Endocrine Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, OX3 7LJ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.21170DOI Listing
January 2010

Diagnosis and management of vitamin D deficiency.

BMJ 2010 Jan 11;340:b5664. Epub 2010 Jan 11.

Institute of Human Genetics, Newcastle University, International Centre for Life, Newcastle upon Tyne NE1 3BZ.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.b5664DOI Listing
January 2010

Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility.

J Clin Endocrinol Metab 2009 Dec 22;94(12):5139-45. Epub 2009 Oct 22.

Institute of Human Genetics, Newcastle University, Newcastle upon Tyne NE1 3BZ, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2009-1404DOI Listing
December 2009

Thyroid peroxidase forms thionamide-sensitive homodimers: relevance for immunomodulation of thyroid autoimmunity.

J Mol Med (Berl) 2009 Oct 8;87(10):971-80. Epub 2009 Aug 8.

Institute of Human Genetics, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00109-009-0511-y
Publisher Site
http://dx.doi.org/10.1007/s00109-009-0511-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757584PMC
October 2009

Discordance for X-linked hypophosphataemic rickets in identical twin girls.

Horm Res 2009 4;71(4):237-44. Epub 2009 Mar 4.

Institute of Human Genetics, Centre for Life, Newcastle University, Sir James Spence Institute for Child Health, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000201113DOI Listing
June 2009

Autoimmune disorders are among the most frequently encountered conditions in endocrine practice. Preface.

Authors:
Simon H S Pearce

Endocrinol Metab Clin North Am 2009 Jun;38(2):xvii-xviii

Newcastle University, Institute of Human Genetics, International Centre for Life, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S088985290900014
Publisher Site
http://dx.doi.org/10.1016/j.ecl.2009.01.013DOI Listing
June 2009

Genetics of type 1 diabetes and autoimmune thyroid disease.

Endocrinol Metab Clin North Am 2009 Jun;38(2):289-301, vii-viii

Institute of Human Genetics, University of Newcastle, International Centre for Life, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ecl.2009.01.012DOI Listing
June 2009

Trends in thyroid hormone prescribing and consumption in the UK.

BMC Public Health 2009 May 11;9:132. Epub 2009 May 11.

Endocrine Unit, Royal Victoria Infirmary and Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2458-9-132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683823PMC
May 2009

The influence of age on the relationship between subclinical hypothyroidism and ischemic heart disease: a metaanalysis.

J Clin Endocrinol Metab 2008 Aug 27;93(8):2998-3007. Epub 2008 May 27.

Department of Endocrinology, Queen Elizabeth Hospital, Gateshead, NE9 6SX, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2008-0167DOI Listing
August 2008

Sun and melanoma: Time to go to get your hat.

BMJ 2008 Aug 6;337:a1130. Epub 2008 Aug 6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.a1130DOI Listing
August 2008

Management of hypothyroidism in adults.

BMJ 2008 Jul 28;337:a801. Epub 2008 Jul 28.

Department of Endocrinology, Royal Devon and Exeter Hospital, Exeter.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.a801DOI Listing
July 2008

Unrecognised severe vitamin D deficiency.

BMJ 2008 Jun;336(7657):1371-4

Endocrine Unit, Royal Victoria Infirmary, Newcastle Upon Tyne NE1 4LP.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.39555.820394.BEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427091PMC
June 2008

Radioiodine treatment for benign thyroid disorders: results of a nationwide survey of UK endocrinologists.

Clin Endocrinol (Oxf) 2008 May 31;68(5):814-20. Epub 2007 Oct 31.

Department of Endocrinology, Royal Devon and Exeter Hospital, Exeter, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2265.2007.03097.xDOI Listing
May 2008

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2007.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680141PMC
November 2007

Do antithyroid drugs influence outcome after radioiodine therapy for hyperthyroidism?

Nat Clin Pract Endocrinol Metab 2007 Sep 17;3(9):628-9. Epub 2007 Jul 17.

Newcastle University, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncpendmet0584DOI Listing
September 2007

Genomic polymorphism at the interferon-induced helicase (IFIH1) locus contributes to Graves' disease susceptibility.

J Clin Endocrinol Metab 2007 Aug 29;92(8):3338-41. Epub 2007 May 29.

Institute of Human Genetics, Newcastle University, Newcastle upon Tyne NE1 3BZ, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2007-0173DOI Listing
August 2007

Analysis of the Fc receptor-like-3 (FCRL3) locus in Caucasians with autoimmune disorders suggests a complex pattern of disease association.

J Clin Endocrinol Metab 2007 Mar 2;92(3):1106-11. Epub 2007 Jan 2.

Institute of Human Genetics, University of Newcastle, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2006-2183DOI Listing
March 2007

Left ventricular apical ballooning (takotsubo cardiomyopathy) in thyrotoxicosis.

Thyroid 2007 Feb;17(2):181-2

Department of Cardiology, Royal Victoria Infirmary, Newcastle Upon Tyne, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/thy.2006.0102DOI Listing
February 2007

Genetic association studies of the FOXP3 gene in Graves' disease and autoimmune Addison's disease in the United Kingdom population.

J Mol Endocrinol 2006 Aug;37(1):97-104

Institute of Human Genetics, International Centre for Life, University of Newcastle, Central Parkway, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1677/jme.1.02072DOI Listing
August 2006

What is the evidence behind the evidence-base? The premature death of block-replace antithyroid drug regimens for Graves' disease.

Eur J Endocrinol 2006 Jun;154(6):783-6

Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/eje.1.02169DOI Listing
June 2006

Genetic progress towards the molecular basis of autoimmunity.

Trends Mol Med 2006 Feb 18;12(2):90-8. Epub 2006 Jan 18.

Institute of Human Genetics, International Centre for Life, Central Parkway, University of Newcastle, Newcastle upon Tyne, NE1 3BZ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmed.2005.12.005DOI Listing
February 2006

Genetic progress towards the molecular basis of common autoimmunity.

Discov Med 2006 Feb;6(31):40-5

Department of Biochemistry, University of Otago, Box 56, 710 Cumberland Street, Dunedin, New Zealand.

View Article

Download full-text PDF

Source
February 2006

No association of the codon 55 methionine to valine polymorphism in the SUMO4 gene with Graves' disease.

Clin Endocrinol (Oxf) 2005 Mar;62(3):362-5

Institute of Human Genetics and School of Clinical Medical Sciences, University of Newcastle, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2265.2005.02224.xDOI Listing
March 2005

Spontaneous reporting of adverse reactions to carbimazole and propylthiouracil in the UK.

Authors:
Simon H S Pearce

Clin Endocrinol (Oxf) 2004 Nov;61(5):589-94

School of Clinical Medical Sciences, University of Newcastle, Newcastle upon Tyne, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2265.2004.02135.xDOI Listing
November 2004

Role of the CD40 locus in Graves' disease.

Thyroid 2004 Jul;14(7):506-9

Institute of Human Genetics, University of Newcastle upon Tyne, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/1050725041517039DOI Listing
July 2004

Toward precise forecasting of autoimmune endocrinopathy.

J Clin Endocrinol Metab 2004 Feb;89(2):544-7

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2003-032142DOI Listing
February 2004

Mutational analysis of the FOXP3 gene and evidence for genetic heterogeneity in the immunodysregulation, polyendocrinopathy, enteropathy syndrome.

J Clin Endocrinol Metab 2003 Dec;88(12):6034-9

Institute of Human Genetics and Department of Child Health, University of Newcastle upon Tyne, United Kingdom.

View Article

Download full-text PDF

Source
https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
Publisher Site
http://dx.doi.org/10.1210/jc.2003-031080DOI Listing
December 2003

Extracellular calcium-sensing receptor dysfunction is associated with two new phenotypes.

Clin Endocrinol (Oxf) 2003 Oct;59(4):419-21

School of Clinical Medical Sciences, University of Newcastle Upon Tyne, Newcastle, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1046/j.1365-2265.2003.01869.xDOI Listing
October 2003

Clinical disorders of extracellular calcium-sensing and the molecular biology of the calcium-sensing receptor.

Authors:
Simon H S Pearce

Ann Med 2002 ;34(3):201-6

School of Clinical Medical Sciences, Institute of Human Genetics, University of Newcastle upon Tyne, United Kingdom.

View Article

Download full-text PDF

Source
January 2003

Disordered calcium crystal handling in antisense CLC-5-treated collecting duct cells.

Biochem Biophys Res Commun 2003 Jan;300(2):305-10

Department of Medicine, University of Newcastle Upon Tyne, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0006-291x(02)02837-1DOI Listing
January 2003

The genetics of autoimmune thyroid disease.

J Clin Endocrinol Metab 2002 Dec;87(12):5385-97

School of Clinical Medical Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 3BZ, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2002-020492DOI Listing
December 2002