Publications by authors named "Simon C Richardson"

21Publications

Leishmania aethiopica cell-to-cell spreading involves caspase-3, AkT, and NF-κB but not PKC-δ activation and involves uptake of LAMP-1-positive bodies containing parasites.

Authors:
Medhavi Ranatunga Rajeev Rai Simon C W Richardson Paul Dyer Laurence Harbige Andrew Deacon Lauren Pecorino Giulia T M Getti

FEBS J 2020 05 20;287(9):1777-1797. Epub 2019 Dec 20.

University of Greenwich at Medway, Kent, UK.

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May 2020

Fitness costs associated with infections of secondary endosymbionts in the cassava whitefly species .

Authors:
Saptarshi Ghosh Sophie Bouvaine Simon C W Richardson Murad Ghanim M N Maruthi

J Pest Sci (2004) 2018 22;91(1):17-28. Epub 2017 Aug 22.

1Natural Resources Institute, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB UK.

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August 2017

The potential of toxin-based drug delivery systems for enhanced nucleic acid therapeutic delivery.

Authors:
Susan A Shorter Alexander S Gollings Monique A M Gorringe-Pattrick J Emma Coakley Paul D R Dyer Simon C W Richardson

Expert Opin Drug Deliv 2017 May 7;14(5):685-696. Epub 2016 Sep 7.

a Intracellular Delivery Solutions Laboratory, Department of Life and Sports Science, Faculty of Engineering and Science , University of Greenwich at Medway , Kent , UK.

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May 2017

An in vitro evaluation of epigallocatechin gallate (eGCG) as a biocompatible inhibitor of ricin toxin.

Authors:
Paul D R Dyer Arun K Kotha Alex S Gollings Susan A Shorter Thomas R Shepherd Marie W Pettit Bruce D Alexander Giulia T M Getti Samer El-Daher Les Baillie Simon C W Richardson

Biochim Biophys Acta 2016 Jul 23;1860(7):1541-50. Epub 2016 Mar 23.

Department of Life and Sports Science, University of Greenwich, Central Avenue, Chatham, Kent ME4 4TB, UK. Electronic address:

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July 2016

Disarmed anthrax toxin delivers antisense oligonucleotides and siRNA with high efficiency and low toxicity.

Authors:
Paul D R Dyer Thomas R Shepherd Alexander S Gollings Susan A Shorter Monique A M Gorringe-Pattrick Chun-Kit Tang Beatrice N Cattoz Les Baillie Peter C Griffiths Simon C W Richardson

J Control Release 2015 Dec 9;220(Pt A):316-328. Epub 2015 Nov 9.

Intercellular Delivery Solutions Laboratory, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK. Electronic address:

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December 2015

Development and functional characterization of alginate dressing as potential protein delivery system for wound healing.

Authors:
Frederick U Momoh Joshua S Boateng Simon C W Richardson Babur Z Chowdhry John C Mitchell

Int J Biol Macromol 2015 Nov 26;81:137-50. Epub 2015 Jul 26.

Department of Pharmaceutical Chemical and Environmental Sciences, Faculty of Engineering and Science, University of Greenwich at Medway, Central Avenue, Chatham Maritime, ME4 4TB Kent, UK.

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November 2015

Construction and physiochemical characterisation of a multi-composite, potential oral vaccine delivery system (VDS).

Authors:
Marie W Pettit Paul D R Dyer John C Mitchell Peter C Griffiths Bruce Alexander Beatrice Cattoz Richard K Heenan Stephen M King Ralf Schweins Frank Pullen Stephen R Wicks Simon C W Richardson

Int J Pharm 2014 Jul 26;468(1-2):264-71. Epub 2014 Mar 26.

Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent ME4 4TB, UK. Electronic address:

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July 2014

Imaging select mammalian organelles using fluorescent microscopy: application to drug delivery.

Authors:
Paul D R Dyer Arun K Kotha Marie W Pettit Simon C W Richardson

Methods Mol Biol 2013 ;991:195-209

School of Science, University of Greenwich, Kent, UK.

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September 2013

Self-assembled PAA-based nanoparticles as potential gene and protein delivery systems.

Authors:
Peter C Griffiths Nicolo Mauro Damien M Murphy Emma Carter Simon C W Richardson Paul Dyer Paolo Ferruti

Macromol Biosci 2013 May 19;13(5):641-9. Epub 2013 Mar 19.

Faculty of Engineering and Science, University of Greenwich, Medway Campus, Central Avenue, Chatham Maritime, Kent ME4 4TB, UK.

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May 2013

Endocytosis and intracellular trafficking as gateways for nanomedicine delivery: opportunities and challenges.

Authors:
Ruth Duncan Simon C W Richardson

Mol Pharm 2012 Sep 20;9(9):2380-402. Epub 2012 Aug 20.

School of Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK.

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September 2012

Poly(amidoamine) polymers: soluble linear amphiphilic drug-delivery systems for genes, proteins and oligonucleotides.

Authors:
Marie W Pettit Peter Griffiths Paolo Ferruti Simon C W Richardson

Ther Deliv 2011 Jul;2(7):907-17

School of Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent ME4 4TB, UK.

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July 2011

Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus.

Authors:
Xi Liu Jennifer Hein Simon C W Richardson Per H Basse Tuna Toptan Patrick S Moore Ole V Gjoerup Yuan Chang

J Biol Chem 2011 May 16;286(19):17079-90. Epub 2011 Mar 16.

Cancer Virology Program, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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May 2011

Delivery of biologics to select organelles--the role of biologically active polymers.

Authors:
Paul D R Dyer Simon C W Richardson

Expert Opin Drug Deliv 2011 Apr 12;8(4):403-7. Epub 2011 Feb 12.

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April 2011

Studies on the mechanism of action of dextrin-phospholipase A2 and its suitability for use in combination therapy.

Authors:
Elaine L Ferguson Simon C W Richardson Ruth Duncan

Mol Pharm 2010 Apr;7(2):510-21

Centre for Polymer Therapeutics, Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3XF, UK.

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April 2010

Intracellular fate of bioresponsive poly(amidoamine)s in vitro and in vivo.

Authors:
Simon C W Richardson Nicola G Pattrick Nathalie Lavignac Paolo Ferruti Ruth Duncan

J Control Release 2010 Feb 12;142(1):78-88. Epub 2009 Oct 12.

School of Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, England, ME4 4TB, UK.

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February 2010

Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity.

Authors:
John Spencer Rajendra P Rathnam Mahesh Motukuri Arun K Kotha Simon C W Richardson Ali Hazrati John A Hartley Louise Male Michael B Hursthouse

Dalton Trans 2009 Jun 29(22):4299-303. Epub 2009 Jan 29.

School of Science, University of Greenwich at Medway, Chatham Maritime, UK.

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June 2009

Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones.

Authors:
John Spencer Andrew P Mendham Arun K Kotha Simon C W Richardson Elizabeth A Hillard Gérard Jaouen Louise Male Michael B Hursthouse

Dalton Trans 2009 Feb 18(6):918-21. Epub 2008 Nov 18.

School of Science, University of Greenwich at Medway, Chatham Maritime, UKME4 4TB.

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February 2009

The use of fluorescence microscopy to define polymer localisation to the late endocytic compartments in cells that are targets for drug delivery.

Authors:
Simon C W Richardson Kerri-Lee Wallom Elaine L Ferguson Samuel P E Deacon Matthew W Davies Alison J Powell Robert C Piper Ruth Duncan

J Control Release 2008 Apr 4;127(1):1-11. Epub 2008 Jan 4.

Centre for Polymer Therapeutics, Welsh School of Pharmacy, Cardiff University, Redwood Building, King Edward VII Av, Cardiff, Wales CF10 3XF, UK.

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April 2008

Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.

Authors:
Yanling Zhang Sergey N Zolov Clement Y Chow Shalom G Slutsky Simon C Richardson Robert C Piper Baoli Yang Johnathan J Nau Randal J Westrick Sean J Morrison Miriam H Meisler Lois S Weisman

Proc Natl Acad Sci U S A 2007 Oct 23;104(44):17518-23. Epub 2007 Oct 23.

Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109-2216, USA.

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October 2007

Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.

Authors:
Paul R Pryor Barbara M Mullock Nicholas A Bright Margaret R Lindsay Sally R Gray Simon C W Richardson Abigail Stewart David E James Robert C Piper J Paul Luzio

EMBO Rep 2004 Jun 7;5(6):590-5. Epub 2004 May 7.

Cambridge Institute for Medical Research and Department of Clinical Biochemistry, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.

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June 2004

Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.

Authors:
Simon C W Richardson Stanley C Winistorfer Viviane Poupon J Paul Luzio Robert C Piper

Mol Biol Cell 2004 Mar 10;15(3):1197-210. Epub 2003 Dec 10.

Department of Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, USA.

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March 2004