Publications by authors named "Simeen Malik"

9Publications

An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia.

Authors:
Tun Kiat Ko Asif Javed Kian Leong Lee Thushangi N Pathiraja Xingliang Liu Simeen Malik Sheila Xinxuan Soh Xiu Ting Heng Naoto Takahashi Joanna H J Tan Ravi Bhatia Alexis J Khng Wee-Joo Chng Yee Yen Sia David A Fruman King Pan Ng Zhu En Chan Kim Jiajing Xie Qiangze Hoi Cheryl Xueli Chan Audrey S M Teo Oscar Velazquez Camacho Wee Yang Meah Chiea Chuen Khor Chin Thing J Ong Wei Jia W Soon Patrick Tan Pauline C Ng Charles Chuah Axel M Hillmer S Tiong Ong

Blood 2020 Jun;135(26):2337-2353

Cancer & Stem Cell Biology Signature Research Programme, Duke-NUS Medical School, Singapore.

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June 2020

Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas.

Authors:
Sock Hoai Chan Weng Khong Lim Nur Diana Binte Ishak Shao-Tzu Li Wei Lin Goh Gek San Tan Kiat Hon Lim Melissa Teo Cedric Ng Chuan Young Simeen Malik Mann Hong Tan Jonathan Yi Hui Teh Francis Kuok Choon Chin Sittampalam Kesavan Sathiyamoorthy Selvarajan Patrick Tan Bin Tean Teh Khee Chee Soo Mohamad Farid Richard Quek Joanne Ngeow

Sci Rep 2017 09 6;7(1):10660. Epub 2017 Sep 6.

Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre, Singapore, 169610, Singapore.

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September 2017

Technical Validation of a Next-Generation Sequencing Assay for Detecting Actionable Mutations in Patients with Gastrointestinal Cancer.

Authors:
Sophie R Wang Simeen Malik Iain B Tan Yang Sun Chan Qiangze Hoi Jack L Ow Cassandra Z He Cindy E Ching Dianne Y S Poh Hui Maan Seah Katie H T Cheung Dharuman Perumal Arun G Devasia Lu Pan Shimin Ang Seow Eng Lee Rachel Ten Clarinda Chua Daniel S W Tan James Z Z Qu Yasmin M Bylstra Lionel Lim Alexander Lezhava Pauline C Ng Christopher W Wong Tony Lim Patrick Tan

J Mol Diagn 2016 05 9;18(3):416-424. Epub 2016 Mar 9.

Genome Institute of Singapore, Singapore; Cancer & Stem Cell Biology Program, Duke-National University of Singapore Graduate Medical School, Singapore; Cancer Science Institute Singapore, National University of Singapore, Singapore; Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore. Electronic address:

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May 2016

High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.

Authors:
Iain Beehuat Tan Simeen Malik Kalpana Ramnarayanan John R McPherson Dan Liang Ho Yuka Suzuki Sarah Boonhsui Ng Su Yan Kiat Hon Lim Dennis Koh Chew Min Hoe Chung Yip Chan Rachel Ten Brian Kp Goh Alexander Yf Chung Joanna Tan Cheryl Xueli Chan Su Ting Tay Lezhava Alexander Niranjan Nagarajan Axel M Hillmer Choon Leong Tang Clarinda Chua Bin Tean Teh Steve Rozen Patrick Tan

Genome Biol 2015 Feb 12;16:32. Epub 2015 Feb 12.

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February 2015

Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.

Authors:
Masafumi Muratani Niantao Deng Wen Fong Ooi Suling Joyce Lin Manjie Xing Chang Xu Aditi Qamra Su Ting Tay Simeen Malik Jeanie Wu Ming Hui Lee Shenli Zhang Luke Lin Chuen Tan Huihoon Chua Wai Keong Wong Hock Soo Ong London Lucien Ooi Pierce Kah-How Chow Weng Hoong Chan Khee Chee Soo Liang Kee Goh Steve Rozen Bin Tean Teh Qiang Yu Huck Hui Ng Patrick Tan

Nat Commun 2014 Jul 10;5:4361. Epub 2014 Jul 10.

1] Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, 60 Biopolis Street, Genome #02-01, Singapore 138672, Singapore [2] Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, 8 College Road, Singapore 169857, Singapore [3] Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, #12-01, Singapore 117599, Singapore [4] Cellular and Molecular Research, National Cancer Centre, 11 Hospital Drive, Singapore 169610, Singapore.

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July 2014

Genome-scale analysis of aberrant DNA methylation in colorectal cancer.

Authors:
Toshinori Hinoue Daniel J Weisenberger Christopher P E Lange Hui Shen Hyang-Min Byun David Van Den Berg Simeen Malik Fei Pan Houtan Noushmehr Cornelis M van Dijk Rob A E M Tollenaar Peter W Laird

Genome Res 2012 Feb 9;22(2):271-82. Epub 2011 Jun 9.

Department of Surgery and Department of Biochemistry and Molecular Biology, University of Southern California, USC Epigenome Center, Los Angeles, California 90089-9601, USA.

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February 2012

Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth.

Authors:
Angelo J Casa Adam S Potter Simeen Malik ZaWaunyka Lazard Isere Kuiatse Hee-Tae Kim Anna Tsimelzon Chad J Creighton Susan G Hilsenbeck Powell H Brown Steffi Oesterreich Adrian V Lee

Breast Cancer Res Treat 2012 Feb 4;132(1):61-73. Epub 2011 May 4.

Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.

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February 2012

Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM.

Authors:
Simeen Malik Shiming Jiang Jason P Garee Eric Verdin Adrian V Lee Bert W O'Malley Mao Zhang Narasimhaswamy S Belaguli Steffi Oesterreich

Mol Cell Biol 2010 Jan 16;30(2):399-412. Epub 2009 Nov 16.

Department of Molecular and Cellular Biology, 3 Baylor College of Medicine, Houston, Texas 77030, USA.

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January 2010

Estrogen-mediated downregulation of CD24 in breast cancer cells.

Authors:
Benny Abraham Kaipparettu Simeen Malik Santhi D Konduri Wensheng Liu Matjaz Rokavec Heiko van der Kuip Reiner Hoppe Stephanie Hammerich-Hille Peter Fritz Werner Schroth Ina Abele Gokul M Das Steffi Oesterreich Hiltrud Brauch

Int J Cancer 2008 Jul;123(1):66-72

Division of Molecular Mechanisms of Origin and Treatment of Breast Cancer, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.

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July 2008