Simani Gaseitsiwe

Simani Gaseitsiwe

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Simani Gaseitsiwe

Simani Gaseitsiwe

Publications by authors named "Simani Gaseitsiwe"

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Universal Testing, Expanded Treatment, and Incidence of HIV Infection in Botswana.

N Engl J Med 2019 07;381(3):230-242

From the Botswana-Harvard AIDS Institute Partnership (J. Makhema, T.G., M.M., E.K., U.C., K. Manyake, A.M.M., S.V.S., R. Letlhogile, K. Mukokomani, E.W., S.M., K.M.P., S.L.D.-P., C.K., S.G., H.B., L.O., O.J., E.T.T., M.E., S.L.), the Botswana Ministry of Health and Wellness (R. Lebelonyane, S.E.-H.), and the Centers for Disease Control and Prevention (M.G.A., W.A., T.M., L.A.M., M.R.), Gaborone, Botswana; Harvard T.H. Chan School of Public Health (K.E.W., M.P.H., S.M., K.M.P., S.L.D.-P., V.N., S.G., R.L.S., H.M., V.D., Q.L., R.W., E.T.T., M.E., S.L.), Massachusetts General Hospital (K.M.P.), Brigham and Women's Hospital (S.L.D.-P., S.L.), and Harvard Pilgrim Health Care Institute (R.W.), Boston; Bennett Statistical Consulting, Ballston Lake, NY (K.B.); Goodtables Data Consulting, Norman, OK (J.L.); the Centers for Disease Control and Prevention (J. Moore, P.B., L.B., C.S., E.R., S.P.) and Intellectual Concepts (L.B.), Atlanta; and the Wharton School, University of Pennsylvania, Philadelphia (E.T.T.).

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http://dx.doi.org/10.1056/NEJMoa1812281DOI Listing
July 2019

Next-Generation Whole Genome Sequencing: Opportunities and Challenges.

Tuberc Res Treat 2018 9;2018:1298542. Epub 2018 Dec 9.

KwaZulu-Natal Research Innovation and Sequencing Platform, University of KwaZulu-Natal, Durban, South Africa.

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https://www.hindawi.com/journals/trt/2018/1298542/
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http://dx.doi.org/10.1155/2018/1298542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304523PMC
December 2018

Prevalence of oncogenic human papillomavirus genotypes in patients diagnosed with anogenital malignancies in Botswana.

BMC Infect Dis 2017 11 25;17(1):731. Epub 2017 Nov 25.

Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Botswana, Private Bag UB072, 4775 Notwane Rd., Gaborone, Botswana.

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http://dx.doi.org/10.1186/s12879-017-2832-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702116PMC
November 2017

Brief Report: High Sensitivity and Specificity of the Cepheid Xpert HIV-1 Qualitative Point-of-Care Test Among Newborns in Botswana.

J Acquir Immune Defic Syndr 2017 08;75(5):e128-e131

*Harvard Medical School, Doris Duke International Clinical Research Fellowship, Boston, MA; †David Geffen School of Medicine, University of California, Los Angeles, CA; ‡Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; §Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA; ‖Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA; and ¶Division of Infectious Disease, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000001384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503760PMC
August 2017

Analysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in Botswana.

PLoS One 2016 23;11(8):e0160649. Epub 2016 Aug 23.

Wellcome Trust Africa Centre for Health and Population Studies, Dorris Duke Medical Research Centre, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160649PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994946PMC
July 2017

Deciphering Multiplicity of HIV-1C Infection: Transmission of Closely Related Multiple Viral Lineages.

PLoS One 2016 28;11(11):e0166746. Epub 2016 Nov 28.

Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166746PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125632PMC
June 2017

Genome-Wide Analyses Reveal Gene Influence on HIV Disease Progression and HIV-1C Acquisition in Southern Africa.

AIDS Res Hum Retroviruses 2017 06 6;33(6):597-609. Epub 2017 Apr 6.

1 Harvard T.H. Chan School of Public Health AIDS Initiative, Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health , Boston, Massachusetts.

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http://dx.doi.org/10.1089/AID.2016.0017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467143PMC
June 2017

Pairwise diversity and tMRCA as potential markers for HIV infection recency.

Medicine (Baltimore) 2017 Feb;96(6):e6041

aDivision of Medical Virology, Stellenbosch University, Tygerberg, South Africa bBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana cAfrica Health Research Institute, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, Republic of South Africa dHarvard T.H. Chan School of Public Health, Boston, MA, USA eNational Health Laboratory Services (NHLS), Tygerberg Coastal, South Africa fResearch Department of Infection, University College London, London, United Kingdom gCollege of Health Sciences, University of KwaZulu-Natal, Durban, Republic of South Africa hDivision of Sleep Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1097/MD.0000000000006041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313003PMC
February 2017

Plasma Cytokine Levels in Chronic Asymptomatic HIV-1 Subtype C Infection as an Indicator of Disease Progression in Botswana: A Retrospective Case Control Study.

AIDS Res Hum Retroviruses 2016 Apr 21;32(4):364-9. Epub 2015 Oct 21.

1 Botswana-Harvard School of Public Health AIDS Initiative Partnership for HIV Research and Education (BHP) , Gaborone, Botswana .

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http://dx.doi.org/10.1089/AID.2015.0163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220552PMC
April 2016

Identifying Recent HIV Infections: From Serological Assays to Genomics.

Viruses 2015 Oct 23;7(10):5508-24. Epub 2015 Oct 23.

Africa Centre for Health and Population Studies, Doris Duke Medical Research Centre, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban 4041, South Africa.

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http://dx.doi.org/10.3390/v7102887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632395PMC
October 2015

Whole CMV proteome pattern recognition analysis after HSCT identifies unique epitope targets associated with the CMV status.

PLoS One 2014 16;9(4):e89648. Epub 2014 Apr 16.

CAST (Center for allogeneic stem cell transplantation), Karolinska Hospital; Division of Therapeutic Immunology (TIM), LabMed Karolinska Institutet, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089648PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989190PMC
January 2015

Research capacity. Enabling the genomic revolution in Africa.

Authors:
Charles Rotimi Akin Abayomi Alash'le Abimiku Victoria May Adabayeri Clement Adebamowo Ezekiel Adebiyi Adebowale D Ademola Adebowale Adeyemo Dwomoa Adu Dissou Affolabi Godfred Agongo Samuel Ajayi Sally Akarolo-Anthony Rufus Akinyemi Albert Akpalu Marianne Alberts Orlando Alonso Betancourt Ahmed Mansour Alzohairy Gobena Ameni Olukemi Amodu Gabriel Anabwani Kristian Andersen Fatiu Arogundade Oyedunni Arulogun Danny Asogun Rasheed Bakare Naby Balde Mary Lynn Baniecki Christine Beiswanger Alia Benkahla Lara Bethke Micheal Boehnke Vincent Boima James Brandful Andrew I Brooks Frank C Brosius Chester Brown Bruno Bucheton David T Burke Barrington G Burnett Stacy Carrington-Lawrence Nadia Carstens John Chisi Alan Christoffels Richard Cooper Heather Cordell Nigel Crowther Talishiea Croxton Jantina de Vries Leslie Derr Peter Donkor Seydou Doumbia Audrey Duncanson Ivy Ekem Ahmed El Sayed Mark E Engel John C K Enyaru Dean Everett Faisal M Fadlelmola Eyitayo Fakunle Kenneth H Fischbeck Anne Fischer Onikepe Folarin Junaid Gamieldien Robert F Garry Simani Gaseitsiwe Rasheed Gbadegesin Anita Ghansah Maria Giovanni Parham Goesbeck F Xavier Gomez-Olive Donald S Grant Ravnit Grewal Mark Guyer Neil A Hanchard Christian T Happi Scott Hazelhurst Branwen J Hennig Christiane Hertz- Fowler Winston Hide Friedhelm Hilderbrandt Christopher Hugo-Hamman Muntaser E Ibrahim Regina James Yasmina Jaufeerally-Fakim Carolyn Jenkins Ute Jentsch Pan-Pan Jiang Moses Joloba Victor Jongeneel Fourie Joubert Mukthar Kader Kathleen Kahn Pontiano Kaleebu Saidi H Kapiga Samar Kamal Kassim Ishmael Kasvosve Jonathan Kayondo Bernard Keavney Adeodata Kekitiinwa Sheik Humarr Khan Paul Kimmel Mary-Claire King Robert Kleta Mathurin Koffi Jeffrey Kopp Matthias Kretzler Judit Kumuthini Samuel Kyobe Catherine Kyobutungi Daniel T Lackland Karen A Lacourciere Guida Landouré Rita Lawlor Thomas Lehner Maia Lesosky Naomi Levitt Katherine Littler Zane Lombard Jeanne F Loring Sylvester Lyantagaye Annette Macleod Ebony B Madden Chengetai R Mahomva Julie Makani Manmak Mamven Marape Marape Graeme Mardon Patricia Marshall Darren P Martin Daniel Masiga Robin Mason Michael Mate-Kole Enock Matovu Mary Mayige Bongani M Mayosi Jean Claude Mbanya Sheryl A McCurdy Mark I McCarthy Helen McIlleron S O Mc'Ligeyo Corrine Merle Ana Olga Mocumbi Charles Mondo John V Moran Ayesha Motala Marva Moxey-Mims Wata Sununguko Mpoloka Chisomo L Msefula Thuli Mthiyane Nicola Mulder Gebregziab her Mulugeta Dieuodonne Mumba John Musuku Mo Nagdee Oyekanmi Nash Daouda Ndiaye Anh Quynh Nguyen Mark Nicol Oathokwa Nkomazana Shane Norris Betty Nsangi Alexander Nyarko Moffat Nyirenda Eileen Obe Reginald Obiakor Abraham Oduro Solomon F Ofori-Acquah Okechukwu Ogah Stephen Ogendo Kwaku Ohene-Frempong Akinlolu Ojo Timothy Olanrewaju John Oli Charlotte Osafo Odile Ouwe Missi Oukem-Boyer Bruce Ovbiagele Andrew Owen Mayowa Ojo Owolabi Lukman Owolabi Ellis Owusu-Dabo Guillaume Pare Rulan Parekh Hugh G Patterton Margaret B Penno Jane Peterson Rembert Pieper Jacob Plange-Rhule Martin Pollak Julia Puzak Rajkumar S Ramesar Michele Ramsay Rebekah Rasooly Shiksha Reddy Pardis C Sabeti Kwamena Sagoe Tunde Salako Oumar Samassékou Manjinder S Sandhu Osman Sankoh Fred Stephen Sarfo Marie Sarr Gasnat Shaboodien Issa Sidibe Gustave Simo Martin Simuunza Liam Smeeth Eugene Sobngwi Himla Soodyall Hermann Sorgho Oumou Sow Bah Sudha Srinivasan Dan J Stein Ezra S Susser Carmen Swanepoel Godfred Tangwa Andrew Tareila Ozlem Tastan Bishop Bamidele Tayo Nicki Tiffin Halidou Tinto Ekaete Tobin Stephen Meir Tollman Mahamadou Traoré Marsha J Treadwell Jennifer Troyer Masego Tsimako-Johnstone Vincent Tukei Ifeoma Ulasi Nzovu Ulenga Beverley van Rooyen Ablo Prudence Wachinou Salina P Waddy Alisha Wade Misaki Wayengera James Whitworth Louise Wideroff Cheryl A Winkler Sarah Winnicki Ambroise Wonkam Mengistu Yewondwos Tadase sen Nathan Yozwiak Heather Zar

Science 2014 Jun;344(6190):1346-8

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http://dx.doi.org/10.1126/science.1251546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138491PMC
June 2014

The preferential selection of K65R in HIV-1 subtype C is attenuated by nucleotide polymorphisms at thymidine analogue mutation sites.

J Antimicrob Chemother 2013 Oct 7;68(10):2192-6. Epub 2013 Jun 7.

McGill University AIDS Centre, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montréal, Québec, Canada.

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http://dx.doi.org/10.1093/jac/dkt204DOI Listing
October 2013

No clinically significant drug-resistance mutations in HIV-1 subtype C-infected women after discontinuation of NRTI-based or PI-based HAART for PMTCT in Botswana.

J Acquir Immune Defic Syndr 2013 Aug;63(5):572-7

*Botswana-Harvard AIDS Institute Partnership for HIV Research and Education, Gaborone, Botswana; †Department of Pathology, School of Medicine, University of Botswana, Gaborone, Botswana; ‡Harvard University, Cambridge, MA; §Department of Medicine and Pediatrics, Massachusetts General Hospital, Boston, MA; ‖Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA; ¶Department of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA; and #Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0b013e31829308f8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762949PMC
August 2013

Persistently elevated serum interleukin-6 predicts mortality among adults receiving combination antiretroviral therapy in Botswana: results from a clinical trial.

AIDS Res Hum Retroviruses 2013 Jul 9;29(7):993-9. Epub 2013 May 9.

Harvard School of Public Health AIDS Initiative, Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1089/aid.2012.0309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685692PMC
July 2013

Humoral 'reactome' profiles using peptide microarray chips.

Trends Immunol 2010 Nov 1;31(11):399-400. Epub 2010 Oct 1.

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http://dx.doi.org/10.1016/j.it.2010.08.007DOI Listing
November 2010

Peptide microarray-based identification of Mycobacterium tuberculosis epitope binding to HLA-DRB1*0101, DRB1*1501, and DRB1*0401.

Clin Vaccine Immunol 2010 Jan 28;17(1):168-75. Epub 2009 Oct 28.

Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, and the Swedish Institute for Infectious Disease Control (SMI), Nobels Väg 18, SE. 17182 Stockholm, Sweden.

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http://dx.doi.org/10.1128/CVI.00208-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812096PMC
January 2010

Identification of MHC class II binding peptides: microarray and soluble MHC class II molecules.

Methods Mol Biol 2009 ;524:417-26

Microbiology and Tumor Cell Biology Center (MTC), Karolinska Institutet and the Swedish National Center for Infectious Disease Control (SMI), Nobels Väg 18, S. 17182 Stockholm, Sweden.

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http://dx.doi.org/10.1007/978-1-59745-450-6_30DOI Listing
July 2009

Identification and testing of control peptides for antigen microarrays.

J Immunol Methods 2009 Apr 20;343(2):68-78. Epub 2009 Jan 20.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden.

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http://dx.doi.org/10.1016/j.jim.2008.12.004DOI Listing
April 2009

HIV-1 subtype C in vitro growth and coreceptor utilization.

Virology 2006 Apr 10;347(2):247-60. Epub 2006 Jan 10.

Botswana-Harvard School of Public Health AIDS Initiative Partnership for HIV Research and Education, Private Bag BO320, Bontleng, Gaborone, Botswana, Africa.

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http://dx.doi.org/10.1016/j.virol.2005.11.047DOI Listing
April 2006

Highly active antiretroviral therapy started during pregnancy or postpartum suppresses HIV-1 RNA, but not DNA, in breast milk.

J Infect Dis 2005 Sep 27;192(5):713-9. Epub 2005 Jul 27.

Department of Immunology and Infectious Diseases, Harvard School of Public Health, and Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1086/432489DOI Listing
September 2005

Major histocompatibility complex class II (HLA-DRB and -DQB) allele frequencies in Botswana: association with human immunodeficiency virus type 1 infection.

Clin Diagn Lab Immunol 2005 Sep;12(9):1020-8

Department of Immunology and Infectious Diseases, Harvard School of Public Health, 651 Huntington Avenue, FXB-402, Boston, MA 02115, USA.

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http://dx.doi.org/10.1128/CDLI.12.9.1020-1028.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1235800PMC
September 2005