Publications by authors named "Silviu-Alin Bacanu"

73Publications

A large-scale genome-wide association study meta-analysis of cannabis use disorder.

Authors:
Emma C Johnson Ditte Demontis Thorgeir E Thorgeirsson Raymond K Walters Renato Polimanti Alexander S Hatoum Sandra Sanchez-Roige Sarah E Paul Frank R Wendt Toni-Kim Clarke Dongbing Lai Gunnar W Reginsson Hang Zhou June He David A A Baranger Daniel F Gudbjartsson Robbee Wedow Daniel E Adkins Amy E Adkins Jeffry Alexander Silviu-Alin Bacanu Tim B Bigdeli Joseph Boden Sandra A Brown Kathleen K Bucholz Jonas Bybjerg-Grauholm Robin P Corley Louisa Degenhardt Danielle M Dick Benjamin W Domingue Louis Fox Alison M Goate Scott D Gordon Laura M Hack Dana B Hancock Sarah M Hartz Ian B Hickie David M Hougaard Kenneth Krauter Penelope A Lind Jeanette N McClintick Matthew B McQueen Jacquelyn L Meyers Grant W Montgomery Ole Mors Preben B Mortensen Merete Nordentoft John F Pearson Roseann E Peterson Maureen D Reynolds John P Rice Valgerdur Runarsdottir Nancy L Saccone Richard Sherva Judy L Silberg Ralph E Tarter Thorarinn Tyrfingsson Tamara L Wall Bradley T Webb Thomas Werge Leah Wetherill Margaret J Wright Stephanie Zellers Mark J Adams Laura J Bierut Jason D Boardman William E Copeland Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Richard A Grucza Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William G Iacono Eric O Johnson Kenneth S Kendler Martin A Kennedy Henry R Kranzler Pamela A F Madden Hermine H Maes Brion S Maher Nicholas G Martin Matthew McGue Andrew M McIntosh Sarah E Medland Elliot C Nelson Bernice Porjesz Brien P Riley Michael C Stallings Michael M Vanyukov Scott Vrieze Lea K Davis Ryan Bogdan Joel Gelernter Howard J Edenberg Kari Stefansson Anders D Børglum Arpana Agrawal

Lancet Psychiatry 2020 Dec 20;7(12):1032-1045. Epub 2020 Oct 20.

Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1016/S2215-0366(20)30339-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674631PMC
December 2020

A method for estimating coherence of molecular mechanisms in major human disease and traits.

BMC Bioinformatics 2020 Oct 21;21(1):473. Epub 2020 Oct 21.

Virginia Institute for Psychiatric and Behavior Genetics and the Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1186/s12859-020-03821-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579960PMC
October 2020

Assessing the Role of Long Noncoding RNA in Nucleus Accumbens in Subjects With Alcohol Dependence.

Alcohol Clin Exp Res 2020 Oct 17. Epub 2020 Oct 17.

Virginia Institute for Psychiatric and Behavioral Genetics, (GOM, ESV, CC, MM, KSK, BPR, MFM, S-AB, VIV), Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1111/acer.14479DOI Listing
October 2020

Assessing the Role of Long Noncoding RNA in Nucleus Accumbens in Subjects With Alcohol Dependence.

Alcohol Clin Exp Res 2020 Oct 17. Epub 2020 Oct 17.

Virginia Institute for Psychiatric and Behavioral Genetics, (GOM, ESV, CC, MM, KSK, BPR, MFM, S-AB, VIV), Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1111/acer.14479DOI Listing
October 2020

TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders.

Am J Med Genet B Neuropsychiatr Genet 2020 Dec 21;183(8):454-463. Epub 2020 Sep 21.

Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA.

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http://dx.doi.org/10.1002/ajmg.b.32823DOI Listing
December 2020

Meta-Analysis of Associations Between Hypothalamic-Pituitary-Adrenal Axis Genes and Risk of Posttraumatic Stress Disorder.

J Trauma Stress 2020 Oct 26;33(5):688-698. Epub 2020 Mar 26.

Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1002/jts.22484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529653PMC
October 2020

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.

Authors:
Melissa A Munn-Chernoff Emma C Johnson Yi-Ling Chou Jonathan R I Coleman Laura M Thornton Raymond K Walters Zeynep Yilmaz Jessica H Baker Christopher Hübel Scott Gordon Sarah E Medland Hunna J Watson Héléna A Gaspar Julien Bryois Anke Hinney Virpi M Leppä Manuel Mattheisen Stephan Ripke Shuyang Yao Paola Giusti-Rodríguez Ken B Hanscombe Roger A H Adan Lars Alfredsson Tetsuya Ando Ole A Andreassen Wade H Berrettini Ilka Boehm Claudette Boni Vesna Boraska Perica Katharina Buehren Roland Burghardt Matteo Cassina Sven Cichon Maurizio Clementi Roger D Cone Philippe Courtet Scott Crow James J Crowley Unna N Danner Oliver S P Davis Martina de Zwaan George Dedoussis Daniela Degortes Janiece E DeSocio Danielle M Dick Dimitris Dikeos Christian Dina Monika Dmitrzak-Weglarz Elisa Docampo Laramie E Duncan Karin Egberts Stefan Ehrlich Geòrgia Escaramís Tõnu Esko Xavier Estivill Anne Farmer Angela Favaro Fernando Fernández-Aranda Manfred M Fichter Krista Fischer Manuel Föcker Lenka Foretova Andreas J Forstner Monica Forzan Christopher S Franklin Steven Gallinger Ina Giegling Johanna Giuranna Fragiskos Gonidakis Philip Gorwood Monica Gratacos Mayora Sébastien Guillaume Yiran Guo Hakon Hakonarson Konstantinos Hatzikotoulas Joanna Hauser Johannes Hebebrand Sietske G Helder Stefan Herms Beate Herpertz-Dahlmann Wolfgang Herzog Laura M Huckins James I Hudson Hartmut Imgart Hidetoshi Inoko Vladimir Janout Susana Jiménez-Murcia Antonio Julià Gursharan Kalsi Deborah Kaminská Leila Karhunen Andreas Karwautz Martien J H Kas James L Kennedy Anna Keski-Rahkonen Kirsty Kiezebrink Youl-Ri Kim Kelly L Klump Gun Peggy S Knudsen Maria C La Via Stephanie Le Hellard Robert D Levitan Dong Li Lisa Lilenfeld Bochao Danae Lin Jolanta Lissowska Jurjen Luykx Pierre J Magistretti Mario Maj Katrin Mannik Sara Marsal Christian R Marshall Morten Mattingsdal Sara McDevitt Peter McGuffin Andres Metspalu Ingrid Meulenbelt Nadia Micali Karen Mitchell Alessio Maria Monteleone Palmiero Monteleone Benedetta Nacmias Marie Navratilova Ioanna Ntalla Julie K O'Toole Roel A Ophoff Leonid Padyukov Aarno Palotie Jacques Pantel Hana Papezova Dalila Pinto Raquel Rabionet Anu Raevuori Nicolas Ramoz Ted Reichborn-Kjennerud Valdo Ricca Samuli Ripatti Franziska Ritschel Marion Roberts Alessandro Rotondo Dan Rujescu Filip Rybakowski Paolo Santonastaso André Scherag Stephen W Scherer Ulrike Schmidt Nicholas J Schork Alexandra Schosser Jochen Seitz Lenka Slachtova P Eline Slagboom Margarita C T Slof-Op't Landt Agnieszka Slopien Sandro Sorbi Beata Świątkowska Jin P Szatkiewicz Ioanna Tachmazidou Elena Tenconi Alfonso Tortorella Federica Tozzi Janet Treasure Artemis Tsitsika Marta Tyszkiewicz-Nwafor Konstantinos Tziouvas Annemarie A van Elburg Eric F van Furth Gudrun Wagner Esther Walton Elisabeth Widen Eleftheria Zeggini Stephanie Zerwas Stephan Zipfel Andrew W Bergen Joseph M Boden Harry Brandt Steven Crawford Katherine A Halmi L John Horwood Craig Johnson Allan S Kaplan Walter H Kaye James Mitchell Catherine M Olsen John F Pearson Nancy L Pedersen Michael Strober Thomas Werge David C Whiteman D Blake Woodside Jakob Grove Anjali K Henders Janne T Larsen Richard Parker Liselotte V Petersen Jennifer Jordan Martin A Kennedy Andreas Birgegård Paul Lichtenstein Claes Norring Mikael Landén Preben Bo Mortensen Renato Polimanti Jeanette N McClintick Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Franziska Degenhardt Anna R Docherty Alexis C Edwards Jerome C Foo Louis Fox Josef Frank Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Colin Hodgkinson Per Hoffmann Jouke-Jan Hottenga Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen Roseann E Peterson Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Hang Zhou Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Mark A Frye Wolfgang Gäebel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer Gabriele Koller John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie H Witt Norbert Wodarz Peter Zill Daniel E Adkins Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz E Jane Costello Harriet de Wit Nancy Diazgranados Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Victor Hesselbrock John K Hewitt Christian J Hopfer William G Iacono Eric O Johnson Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik K E Magnusson Elliot C Nelson Markus M Nöthen Abraham A Palmer Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard J Rose Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Tracey D Wade Andrew C Heath Grant W Montgomery Nicholas G Martin Patrick F Sullivan Jaakko Kaprio Gerome Breen Joel Gelernter Howard J Edenberg Cynthia M Bulik Arpana Agrawal

Addict Biol 2020 Feb 16:e12880. Epub 2020 Feb 16.

Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri, USA.

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http://dx.doi.org/10.1111/adb.12880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429266PMC
February 2020

The impact on estimations of genetic correlations by the use of super-normal, unscreened, and family-history screened controls in genome wide case-control studies.

Genet Epidemiol 2020 04 21;44(3):283-289. Epub 2020 Jan 21.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1002/gepi.22281DOI Listing
April 2020

Genome-wide association study of shared liability to anxiety disorders in Army STARRS.

Am J Med Genet B Neuropsychiatr Genet 2020 06 30;183(4):197-207. Epub 2019 Dec 30.

Department of Family Medicine & Public Health, University of California San Diego, La Jolla, California.

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http://dx.doi.org/10.1002/ajmg.b.32776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210051PMC
June 2020

Pathway-based polygene risk for severe depression implicates drug metabolism in CONVERGE.

Psychol Med 2020 04 2;50(5):793-798. Epub 2019 Apr 2.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, School of Medicine, Richmond, VA, USA.

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http://dx.doi.org/10.1017/S0033291719000618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774907PMC
April 2020

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

The Coherence Problem: Finding Meaning in GWAS Complexity.

Behav Genet 2019 03 16;49(2):187-195. Epub 2018 Nov 16.

Department of Psychiatry and the Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, PO Box 980126, Richmond, VA, 23298, USA.

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http://link.springer.com/10.1007/s10519-018-9935-x
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http://dx.doi.org/10.1007/s10519-018-9935-xDOI Listing
March 2019

Replication of the Interaction of PRKG1 and Trauma Exposure on Alcohol Misuse in an Independent African American Sample.

J Trauma Stress 2018 12 30;31(6):927-932. Epub 2018 Oct 30.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, USA.

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http://doi.wiley.com/10.1002/jts.22339
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http://dx.doi.org/10.1002/jts.22339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295354PMC
December 2018

GxE effects of FKBP5 and traumatic life events on PTSD: A meta-analysis.

J Affect Disord 2019 01 21;243:455-462. Epub 2018 Sep 21.

Department of Psychiatry, Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA; Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183075
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http://dx.doi.org/10.1016/j.jad.2018.09.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487483PMC
January 2019

The Effects of a BDNF Val66Met Polymorphism on Posttraumatic Stress Disorder: A Meta-Analysis.

Neuropsychobiology 2017 6;76(3):136-142. Epub 2018 Jun 6.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, USA.

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https://www.karger.com/Article/FullText/489407
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http://dx.doi.org/10.1159/000489407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057796PMC
June 2018

Method to estimate the approximate samples size that yield a certain number of significant GWAS signals in polygenic traits.

Genet Epidemiol 2018 07 14;42(5):488-496. Epub 2018 May 14.

Psychiatric Department, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1002/gepi.22125DOI Listing
July 2018

Method to estimate the approximate samples size that yield a certain number of significant GWAS signals in polygenic traits.

Genet Epidemiol 2018 07 14;42(5):488-496. Epub 2018 May 14.

Psychiatric Department, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1002/gepi.22125DOI Listing
July 2018

Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression.

Am J Psychiatry 2018 06 2;175(6):545-554. Epub 2018 Mar 2.

From the Virginia Institute for Psychiatric and Behavioral Genetics and the Department of Psychiatry, Virginia Commonwealth University, Richmond, Va.; the Wellcome Trust Sanger Institute, Cambridge, U.K.; the European Bioinformatics Institute (EMBL-EBI), Cambridge, U.K.; the Department of Medicine, University of California, San Francisco; the State University of New York Downstate Medical Center, Brooklyn, N.Y.; and the Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles.

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http://dx.doi.org/10.1176/appi.ajp.2017.17060621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988935PMC
June 2018

Association of Posttraumatic Stress Disorder With rs2267735 in the ADCYAP1R1 Gene: A Meta-Analysis.

J Trauma Stress 2017 08 26;30(4):389-398. Epub 2017 Jul 26.

Bradley/Hasbro Children's Research Center of Rhode Island Hospital, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1002/jts.22211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706560PMC
August 2017

The utility of empirically assigning ancestry groups in cross-population genetic studies of addiction.

Am J Addict 2017 Aug 17;26(5):494-501. Epub 2017 Jul 17.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1111/ajad.12586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646819PMC
August 2017

Sharing extended summary data from contemporary genetics studies is unlikely to threaten subject privacy.

PLoS One 2017 29;12(6):e0179504. Epub 2017 Jun 29.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179504PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491025PMC
September 2017

The Genetic Architecture of Major Depressive Disorder in Han Chinese Women.

JAMA Psychiatry 2017 02;74(2):162-168

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond.

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http://dx.doi.org/10.1001/jamapsychiatry.2016.3578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319866PMC
February 2017

Evaluating the dopamine hypothesis of schizophrenia in a large-scale genome-wide association study.

Schizophr Res 2016 10 20;176(2-3):136-140. Epub 2016 Jun 20.

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, PO Box 980126, Richmond, VA 23298-0126, United States.

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http://dx.doi.org/10.1016/j.schres.2016.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026897PMC
October 2016

CHRONICITY OF DEPRESSION AND MOLECULAR MARKERS IN A LARGE SAMPLE OF HAN CHINESE WOMEN.

Depress Anxiety 2016 Nov 25;33(11):1048-1054. Epub 2016 Apr 25.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079854PMC
http://dx.doi.org/10.1002/da.22517DOI Listing
November 2016

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women.

JAMA Psychiatry 2016 05;73(5):497-505

Schizophrenia Research Institute, Sydney, Australia23School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.

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http://dx.doi.org/10.1001/jamapsychiatry.2016.0129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785705PMC
May 2016

Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence.

PLoS One 2015 18;10(9):e0137671. Epub 2015 Sep 18.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, United States of America; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, United States of America; Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, Richmond, VA, United States of America; Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, MD, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137671PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575063PMC
May 2016

DISTMIX: direct imputation of summary statistics for unmeasured SNPs from mixed ethnicity cohorts.

Bioinformatics 2015 Oct 9;31(19):3099-104. Epub 2015 Jun 9.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1093/bioinformatics/btv348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576696PMC
October 2015

JEPEG: a summary statistics based tool for gene-level joint testing of functional variants.

Bioinformatics 2015 Apr 12;31(8):1176-82. Epub 2014 Dec 12.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Center for Biomarker Research & Personalized Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, MD 21205, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btu816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393522PMC
April 2015

Testing for measured gene-environment interaction: problems with the use of cross-product terms and a regression model reparameterization solution.

Behav Genet 2014 Mar 16;44(2):165-81. Epub 2014 Feb 16.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, 800 E. Leigh St., PO Box 980126, Richmond, VA, 23298-0126, USA,

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http://dx.doi.org/10.1007/s10519-014-9642-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004105PMC
March 2014

Association testing strategy for data from dense marker panels.

PLoS One 2013 12;8(11):e80540. Epub 2013 Nov 12.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080540PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827222PMC
July 2014

The genetic overlap between schizophrenia and height.

Schizophr Res 2013 Dec 12;151(1-3):226-8. Epub 2013 Nov 12.

Department of Psychiatry, Virginia Commonwealth University, United States. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2013.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939673PMC
December 2013

DIST: direct imputation of summary statistics for unmeasured SNPs.

Bioinformatics 2013 Nov 28;29(22):2925-7. Epub 2013 Aug 28.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810851PMC
November 2013

Molecular validation of the schizophrenia spectrum.

Schizophr Bull 2014 Jan 22;40(1):60-5. Epub 2013 Aug 22.

*To whom correspondence should be addressed; Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics of VCU, Box 980126, Richmond, VA 23298-0126, US; tel: (804)-828-8590, fax: (804)-828-1471, e-mail:

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http://dx.doi.org/10.1093/schbul/sbt122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885304PMC
January 2014

Testing for modes of inheritance involving compound heterozygotes.

Genet Epidemiol 2013 Jul 30;37(5):522-8. Epub 2013 Apr 30.

Virginia Institute for Psychiatric and Behavioral Genetics BIOTECH I, Richmond, Virginia, USA.

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http://doi.wiley.com/10.1002/gepi.21732
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http://dx.doi.org/10.1002/gepi.21732DOI Listing
July 2013

RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia.

BMC Genomics 2012 17;13 Suppl 8:S2. Epub 2012 Dec 17.

Department of psychiatry, School of Medicine, University at Buffalo, SUNY, Buffalo, NY 14260, USA.

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http://dx.doi.org/10.1186/1471-2164-13-S8-S2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535722PMC
June 2013

Extracting actionable information from genome scans.

Genet Epidemiol 2013 Jan 19;37(1):48-59. Epub 2012 Sep 19.

Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA.

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January 2013

Comparison of statistical tests for association between rare variants and binary traits.

PLoS One 2012 9;7(8):e42530. Epub 2012 Aug 9.

Quantitative Sciences, GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415421PMC
April 2013

On optimal gene-based analysis of genome scans.

Genet Epidemiol 2012 May 16;36(4):333-9. Epub 2012 Apr 16.

Virginia Commonwealth University, Richmond, Virginia 23219, USA.

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May 2012

Comparison of methods and sampling designs to test for association between rare variants and quantitative traits.

Genet Epidemiol 2011 May;35(4):226-35

GlaxoSmithKline, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1002/gepi.20570DOI Listing
May 2011

Comparison of association methods for dense marker data.

Genet Epidemiol 2008 Dec;32(8):791-9

GlaxoSmithKline, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1002/gepi.20347DOI Listing
December 2008

Are exposure to cytomegalovirus and genetic variation on chromosome 6p joint risk factors for schizophrenia?

Ann Med 2007 ;39(2):145-53

Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1080/07853890601083808DOI Listing
June 2007

Common variations in ALG9 are not associated with bipolar I disorder: a family-based study.

Behav Brain Funct 2006 Jul 21;2:25. Epub 2006 Jul 21.

Department of Obstetrics, Gynecology and Reproductive Sciences, The University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569366PMC
July 2006

Multipoint linkage analysis for a very dense set of markers.

Genet Epidemiol 2005 Nov;29(3):195-203

Genetics Research, GlaxoSmithKline, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1002/gepi.20089DOI Listing
November 2005

Heritability of psychosis in Alzheimer disease.

Am J Geriatr Psychiatry 2005 Jul;13(7):624-7

Dept. of Psychiatry, Univ. of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

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July 2005

Linkage analysis of a completely ascertained sample of familial schizophrenics and bipolars from Palau, Micronesia.

Hum Genet 2005 Aug 25;117(4):349-56. Epub 2005 May 25.

Department of Statistics, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

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August 2005

Characterization of multilocus linkage disequilibrium.

Genet Epidemiol 2005 Apr;28(3):193-206

Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.

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April 2005

Analysis of single-locus tests to detect gene/disease associations.

Genet Epidemiol 2005 Apr;28(3):207-19

Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.

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April 2005

Genomic Control to the extreme.

Nat Genet 2004 Nov;36(11):1129-30; author reply 1131

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November 2004

Robust estimation of critical values for genome scans to detect linkage.

Genet Epidemiol 2005 Jan;28(1):24-32

Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1002/gepi.20030DOI Listing
January 2005

Psychotic symptoms in Alzheimer disease: evidence for subtypes.

Am J Geriatr Psychiatry 2003 Jul-Aug;11(4):406-13

Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

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November 2003

Heritability of fearful-anxious endophenotypes in infant rhesus macaques: a preliminary report.

Biol Psychiatry 2003 Feb;53(4):284-91

Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1016/s0006-3223(02)01601-3DOI Listing
February 2003

Association studies for quantitative traits in structured populations.

Genet Epidemiol 2002 Jan;22(1):78-93

Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

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http://doi.wiley.com/10.1002/gepi.1045
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January 2002

Mixture models for linkage analysis of affected sibling pairs and covariates.

Genet Epidemiol 2002 Jan;22(1):52-65

Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

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http://doi.wiley.com/10.1002/gepi.1043
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January 2002