Silvio E Inzucchi

Silvio E Inzucchi

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Silvio E Inzucchi

Publications by authors named "Silvio E Inzucchi"

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Reports of Lactic Acidosis Attributed to Metformin, 2015-2018.

Diabetes Care 2020 Jan 9;43(1):244-246. Epub 2019 Oct 9.

Yale School of Medicine, New Haven, CT.

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http://dx.doi.org/10.2337/dc19-0923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011199PMC
January 2020

The authors reply.

Kidney Int 2020 Jan;97(1):213-214

Department of Medicine, Division of Nephrology, University Health Network, University of Toronto, Canada; Department of Physiology, Division of Nephrology, University Health Network, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.kint.2019.09.027DOI Listing
January 2020

Are the cardiovascular and kidney benefits of empagliflozin influenced by baseline glucose-lowering therapy?

Diabetes Obes Metab 2019 Dec 2. Epub 2019 Dec 2.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/dom.13938DOI Listing
December 2019

Glucose Control and the Effect of Empagliflozin on Kidney Outcomes in Type 2 Diabetes: An Analysis From the EMPA-REG OUTCOME Trial.

Am J Kidney Dis 2019 Nov 27;74(5):713-715. Epub 2019 Jun 27.

Department of Diabetes, Central Clinical School, Monash University, Melbourne, Australia; Boehringer Ingelheim International GmbH, Ingelheim; Department of Medicine, Würzburg University Clinic, Würzburg, Germany.

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http://dx.doi.org/10.1053/j.ajkd.2019.03.432DOI Listing
November 2019

Diabetes prevention and cardiovascular complications.

Diabetologia 2019 11 14;62(11):2161-2162. Epub 2019 Sep 14.

Section of General Medicine, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1007/s00125-019-04999-3DOI Listing
November 2019

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction.

N Engl J Med 2019 11 19;381(21):1995-2008. Epub 2019 Sep 19.

From the BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom (J.J.V.M., M.C.P., K.F.D., P.S.J.); the Cardiovascular Division (S.D.S., A.S.D.) and the TIMI Study Group, Brigham and Women's Hospital and Harvard Medical School (M.S.S.) - all in Boston; Section of Endocrinology, Yale University School of Medicine, New Haven, CT (S.E.I.); Rigshospitalet Copenhagen University Hospital (L.K.) and the Department of Cardiology, Gentofte University Hospital (M. Schou), Copenhagen; the Department of Medicine, Saarland University Hospital, Homburg-Saar, Germany (M.B.); Saint Luke's Mid America Heart Institute, University of Missouri, Kansas City (M.N.K.); National University of Cordoba, Cordoba (F.A.M.), and the Division of Cardiology, Instituto Cardiovascular de Buenos Aires, Buenos Aires (M.D.) - both in Argentina; Wroclaw Medical University, Wroclaw (P.P.), and the Department of Cardiology, Medical University of Lodz, Lodz (J.D.) - both in Poland; the Department of Cardiology, University of Minnesota, Minneapolis (I.S.A.); 2nd Department of Internal Medicine, Cardiovascular Medicine, General Teaching Hospital and 1st Faculty of Medicine, Charles University, Prague, Czech Republic (J.B.); the Division of Cardiology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan (C.-E.C.); the Department of Cardiology, Medanta, Gurgaon, India (V.K.C.); the Department of Cardiology, University Medical Center and University of Groningen, Groningen, the Netherlands (R.A.B.); the 5th Department of Internal Medicine, Comenius University in Bratislava, Bratislava, Slovakia (A.D.); the Department of Cardiology, Shanghai Institute of Cardiovascular Disease and Zhongshan Hospital Fudan University, Shanghai, China (J.G.); Cumming School of Medicine and Libin Cardiovascular Institute, University of Calgary, Calgary, AB (J.G.H.), the Department of Cardiology, Montreal Heart Institute, Montreal (E.O.), and the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.) - all in Canada; Clinic of Cardiology, National Cardiology Hospital, Sofia, Bulgaria (T.K.); the Cardiovascular Division of Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan (M.K.); the Department of Molecular and Clinical Medicine and Cardiology, Sahlgrenska Academy (C.E.A.L.), and AstraZeneca (O.B., M. Sjöstrand, A.M.L.), Gothenburg, and the Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University (C.H.), Uppsala - all in Sweden; the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.); Instituto do Coracao, Hospital das Clinicas da Faculdade de Medicina, Universidade de São Paolo, São Paolo (J.C.N.); the Department of Internal Medicine, Tan Tao University, Tan Duc, Vietnam (P.N.V.); the Department of Myocardial Disease and Heart Failure, National Medical Research Center of Cardiology, Moscow (S.T.); and the Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison (D.L.D.).

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http://dx.doi.org/10.1056/NEJMoa1911303DOI Listing
November 2019

Efficacy and safety of empagliflozin in older patients in the EMPA-REG OUTCOME® trial.

Age Ageing 2019 11;48(6):859-866

St. Michael's Hospital, Division of Cardiology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/ageing/afz096DOI Listing
November 2019

Dethroning the king?: The future of metformin as first line therapy in type 2 diabetes.

J Diabetes Complications 2019 Jun 21;33(6):462-464. Epub 2019 Mar 21.

Tulane University, United States of America. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10568727193030
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http://dx.doi.org/10.1016/j.jdiacomp.2019.03.003DOI Listing
June 2019

Understanding Contemporary Use of Thiazolidinediones.

Circ Heart Fail 2019 Jun;12(6):e005855

Saint Luke's Mid America Heart Institute (S.V.A., F.T., M.K.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.118.005855DOI Listing
June 2019

Composite cardiovascular risk factor target achievement and its predictors in US adults with diabetes: The Diabetes Collaborative Registry.

Diabetes Obes Metab 2019 05 14;21(5):1121-1127. Epub 2019 Feb 14.

University of California, Irvine School of Medicine, Irvine, California.

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http://dx.doi.org/10.1111/dom.13625DOI Listing
May 2019

FDA guidance on antihyperglyacemic therapies for type 2 diabetes: One decade later.

Diabetes Obes Metab 2019 05 12;21(5):1073-1078. Epub 2019 Mar 12.

Clinical Development, Therapeutic Area Cardiometabolism, Boehringer Ingelheim, Ingelheim, Germany.

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http://dx.doi.org/10.1111/dom.13645DOI Listing
May 2019

Retinopathy Outcomes With Empagliflozin Versus Placebo in the EMPA-REG OUTCOME Trial.

Diabetes Care 2019 04 31;42(4):e53-e55. Epub 2019 Jan 31.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.2337/dc18-1355DOI Listing
April 2019

Evidence supports prediabetes treatment.

Science 2019 04;364(6438):341-342

Division of Endocrinology and Diabetes, University of Virginia, Charlottesville, VA 22903, USA.

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http://dx.doi.org/10.1126/science.aax3548DOI Listing
April 2019

Lorcaserin and Renal Outcomes in Obese and Overweight Patients in the CAMELLIA-TIMI 61 Trial.

Circulation 2019 01;139(3):366-375

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (B.M.S., E.A.B., A.Q., S.A.M., K.I., M.P.B., C.T.R., M.S.S., S.D.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038341DOI Listing
January 2019

Scoring System to Optimize Pioglitazone Therapy After Stroke Based on Fracture Risk.

Stroke 2018 Dec 10:STROKEAHA118022745. Epub 2018 Dec 10.

From the Department of Internal Medicine, General Medicine, Yale University School of Medicine, New Haven, CT (C.M.V., W.N.K.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557695PMC
December 2018

Assessing use of patient-focused pharmacotherapy in glycemic management through the Diabetes Collaborative Registry (DCR).

J Diabetes Complications 2018 Nov 9;32(11):1035-1039. Epub 2018 Aug 9.

Saint Luke's Mid America Heart Institute, Kansas, MO, United States of America; University of Missouri-Kansas City, Kansas, MO, United States of America.

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http://dx.doi.org/10.1016/j.jdiacomp.2018.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021208PMC
November 2018

Use of SGLT2 inhibitors in type 2 diabetes: weighing the risks and benefits.

Diabetologia 2018 10 22;61(10):2118-2125. Epub 2018 Aug 22.

Section of Endocrinology, Yale University School of Medicine, Yale-New Haven Hospital, 333 Cedar Street, FMP 106, P.O. Box 208020, New Haven, CT, 06520, USA.

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http://dx.doi.org/10.1007/s00125-018-4663-6DOI Listing
October 2018

Improvement in Cardiovascular Outcomes With Empagliflozin Is Independent of Glycemic Control.

Circulation 2018 10;138(17):1904-1907

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Ontario, Canada (B.Z.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035759DOI Listing
October 2018

Impact of treatment with pioglitazone on stroke outcomes: A real-world database analysis.

Diabetes Obes Metab 2018 09 4;20(9):2140-2147. Epub 2018 Jun 4.

Pharmatelligence, Cardiff, UK.

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http://dx.doi.org/10.1111/dom.13344DOI Listing
September 2018

Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients.

N Engl J Med 2018 09 26;379(12):1107-1117. Epub 2018 Aug 26.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston (E.A.B., S.D.W., J.K., K.I., A.Q., M.P.B., C.T.R., M.S.S., B.M.S.); the Cardiovascular Division, University of Texas Southwestern Medical Center, Dallas (D.K.M.); the Section of Endocrinology, Yale School of Medicine, New Haven, CT (S.E.I.); the Department of Medicine, University of Minnesota, Minneapolis (C.L.F.); the Partners Clinical Research Centre, Nassau, Bahamas (C.B.); the Department of Cardiology, Postgraduate Medical School, Grochowski Hospital, Warsaw, Poland (A.B.); Cardiolink Clinical Trials, Monterrey, Mexico (A.G.-C.); McMaster University, Brampton, ON (M.G.), and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.) - both in Canada; MedStar Health Research Institute, Hyattsville, MD (N.J.W.); the Cardiology Department, Auckland City Hospital, Auckland, New Zealand (H.D.W.); Eisai, Woodcliff Lake, NJ (T.P., B.F., W.M., C.P., S.D.); National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney (A.C.K.); and the Translational Research Institute for Metabolism and Diabetes, Florida Hospital and the Sanford-Burnham Institute, Winter Park (S.R.S.).

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http://dx.doi.org/10.1056/NEJMoa1808721DOI Listing
September 2018

Empagliflozin in women with type 2 diabetes and cardiovascular disease - an analysis of EMPA-REG OUTCOME®.

Diabetologia 2018 07 30;61(7):1522-1527. Epub 2018 Apr 30.

Division of Cardiology, St Michael's Hospital, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00125-018-4630-2DOI Listing
July 2018

Renoprotective effects of sodium-glucose cotransporter-2 inhibitors.

Kidney Int 2018 07 5;94(1):26-39. Epub 2018 May 5.

Department of Medicine, Division of Nephrology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00852538183012
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http://dx.doi.org/10.1016/j.kint.2017.12.027DOI Listing
July 2018

Levothyroxine pseudo-malabsorption: testing and treatment in the outpatient setting.

Ther Adv Endocrinol Metab 2018 Jul 28;9(7):217-222. Epub 2018 Apr 28.

Yale Section of Endocrinology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1177/2042018818771433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022974PMC
July 2018

Hypoglycemia in type 2 diabetes: understanding patients' and physicians' knowledge and experience.

Endocrine 2018 06 19;60(3):435-444. Epub 2018 Feb 19.

Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.

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http://dx.doi.org/10.1007/s12020-018-1545-0DOI Listing
June 2018

Diabetes medications and cardiovascular disease: at long last progress.

Curr Opin Endocrinol Diabetes Obes 2018 04;25(2):87-93

Section of Endocrinology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1097/MED.0000000000000400DOI Listing
April 2018

Personalizing Glucose-Lowering Therapy in Patients with Type 2 Diabetes and Cardiovascular Disease.

Endocrinol Metab Clin North Am 2018 03;47(1):137-152

Yale Endocrinology, Fitkin 106, Box 208020, New Haven, CT 06520-8020, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2017.10.011DOI Listing
March 2018

Empagliflozin and Clinical Outcomes in Patients With Type 2 Diabetes Mellitus, Established Cardiovascular Disease, and Chronic Kidney Disease.

Circulation 2018 01 13;137(2):119-129. Epub 2017 Sep 13.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada (B.Z.) and Division of Endocrinology, University of Toronto, Canada (B.Z.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.028268DOI Listing
January 2018

Effects of pioglitazone on cognitive function in patients with a recent ischaemic stroke or TIA: a report from the IRIS trial.

J Neurol Neurosurg Psychiatry 2018 01 22;89(1):21-27. Epub 2017 Sep 22.

Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1136/jnnp-2017-316361DOI Listing
January 2018

Empagliflozin and Assessment of Lower-Limb Amputations in the EMPA-REG OUTCOME Trial.

Diabetes Care 2018 01 13;41(1):e4-e5. Epub 2017 Nov 13.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, and Division of Endocrinology and Metabolism, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.2337/dc17-1551DOI Listing
January 2018

Cardiovascular Outcomes and Safety of Empagliflozin in Patients With Type 2 Diabetes Mellitus and Peripheral Artery Disease: A Subanalysis of EMPA-REG OUTCOME.

Circulation 2018 01 13;137(4):405-407. Epub 2017 Nov 13.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada (B.Z.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.032031DOI Listing
January 2018

Bladder cancer in the EMPA-REG OUTCOME trial.

Diabetologia 2017 12 14;60(12):2534-2535. Epub 2017 Sep 14.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Canada.

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http://link.springer.com/10.1007/s00125-017-4430-0
Publisher Site
http://dx.doi.org/10.1007/s00125-017-4430-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448940PMC
December 2017

Smoking cessation and outcome after ischemic stroke or TIA.

Neurology 2017 Oct 8;89(16):1723-1729. Epub 2017 Sep 8.

From the Yale School of Medicine (K.A.E., C.M.V., L.H.Y., S.E.I., B.G., W.N.K.), New Haven, CT; University of Western Ontario (J.D.S.), London, Canada; Maine Medical Center (M.G.), Portland; Fred Hutchinson Cancer Research Center (P.D.G.), Seattle, WA; University of Newcastle Upon Tyne (A.D.), Newcastle, UK; and Alpert Medical School of Brown University (K.L.F.), Providence, RI.

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http://dx.doi.org/10.1212/WNL.0000000000004524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644463PMC
October 2017

Response by Young et al to Letters Regarding Article, "Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack: Effects of Pioglitazone in Patients With Insulin Resistance Without Diabetes Mellitus".

Circulation 2017 10;136(16):1567-1568

From Department of Internal Medicine, Yale University School of Medicine, New Haven, CT (L.H.Y., C.M.V., S.E.I., W.N.K.); and Yale Cardiovascular Research Center, New Haven, CT (L.H.Y.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.030513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683402PMC
October 2017

Mysterious Hyperglycemia: Disease Versus Device.

Clin Diabetes 2017 Oct;35(4):253-256

Yale University School of Medicine, New Haven, CT.

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http://dx.doi.org/10.2337/cd16-0065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669131PMC
October 2017

Shifting Paradigms in the Medical Management of Type 2 Diabetes: Reflections on Recent Cardiovascular Outcome Trials.

J Gen Intern Med 2017 Sep 26;32(9):1044-1051. Epub 2017 May 26.

Section of Endocrinology, Yale School of Medicine and Yale-New Haven Hospital, New Haven, CT, USA.

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http://dx.doi.org/10.1007/s11606-017-4061-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570736PMC
September 2017

Response by Zinman et al to Letter Regarding Article, "Empagliflozin and Cerebrovascular Events in Patients With Type 2 Diabetes Mellitus at High Cardiovascular Risk".

Stroke 2017 09 12;48(9):e256-e257. Epub 2017 Jul 12.

Department of Neurology and Stroke Center, University Hospital Essen, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.117.018125DOI Listing
September 2017

Metformin: clinical use in type 2 diabetes.

Diabetologia 2017 09 2;60(9):1586-1593. Epub 2017 Aug 2.

Section of Endocrinology, Yale School of Medicine and Yale-New Haven Hospital, Fitkin 106, 333 Cedar Street, New Haven, CT, 06520-8020, USA.

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http://dx.doi.org/10.1007/s00125-017-4336-xDOI Listing
September 2017

Is It Time to Change the Type 2 Diabetes Treatment Paradigm? No! Metformin Should Remain the Foundation Therapy for Type 2 Diabetes.

Diabetes Care 2017 08;40(8):1128-1132

Yale School of Medicine, New Haven, CT

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http://dx.doi.org/10.2337/dc16-2372DOI Listing
August 2017

Oral Pharmacologic Treatment of Type 2 Diabetes Mellitus.

Ann Intern Med 2017 07;167(1):73-74

From Yale School of Medicine and Yale-New Haven Hospital, New Haven, Connecticut, and Saint Luke's Mid America Heart Institute and University of Missouri-Kansas City, Kansas City, Missouri.

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http://dx.doi.org/10.7326/L17-0231DOI Listing
July 2017

Pioglitazone and cardiovascular risk reduction: time for a second look?

Cardiovasc Endocrinol 2017 Jun 17;6(2):55-61. Epub 2017 May 17.

Department of Internal Medicine, Section of Endocrinology.

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http://dx.doi.org/10.1097/XCE.0000000000000110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768516PMC
June 2017

Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack: Effects of Pioglitazone in Patients With Insulin Resistance Without Diabetes Mellitus.

Circulation 2017 May 28;135(20):1882-1893. Epub 2017 Feb 28.

From Yale University School of Medicine, New Haven, CT (L.H.Y., C.M.V., J.P.C., S.E.I., A.M.L., D.L.J., S.E.P., W.N.K.); Denver VA Medical Center and University of Colorado School of Medicine (G.G.S., J.D.A.); Alpert Medical School of Brown University, Providence, RI (K.L.F., J.D.A.); Maine Medical Center, Portland (M.J.G.); National Institutes of Health/National Institute of Neurological Disorders and Stroke, Bethesda, MD (R.C.); University of Pennsylvania Perelman School of Medicine, Philadelphia (D.M.K.); and University of Rochester School of Medicine and Dentistry, NY (F.S.L.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511545PMC
May 2017

Empagliflozin and Cerebrovascular Events in Patients With Type 2 Diabetes Mellitus at High Cardiovascular Risk.

Stroke 2017 05 6;48(5):1218-1225. Epub 2017 Apr 6.

From the Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada (B.Z.); Division of Endocrinology (B.Z.) and St Michael's Hospital, Division of Cardiology (D.F.), University of Toronto, Canada; Section of Endocrinology, Yale University School of Medicine, New Haven, CT (S.E.I.); The Biostatistics Center, The George Washington University, Rockville, MD (J.M.L.); Comprehensive Heart Failure Center and Renal Division, University of Wuerzburg and Hospital, Germany (C.W.); Boehringer Ingelheim Pharma GmbH and Co. KG, Ingelheim, Germany (S.K., M.M., H.J.W., U.C.B.); Boehringer Ingelheim Norway KS, Asker (O.E.J.); Department of Neurology and Neurological Sciences, Stanford Stroke Center, CA (G.W.A.); and Department of Neurology and Stroke Center, University Hospital Essen, Germany (H.C.D.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404404PMC
May 2017

The cardiovascular benefits of empagliflozin: SGLT2-dependent and -independent effects.

Diabetologia 2017 03 11;60(3):395-398. Epub 2017 Jan 11.

Internal Medicine 3, Department of Medicine, University of Padua, via Giustiniani 2, 35128, Padova, Italy.

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http://link.springer.com/10.1007/s00125-016-4194-y
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http://dx.doi.org/10.1007/s00125-016-4194-yDOI Listing
March 2017

Heart failure outcomes in clinical trials of glucose-lowering agents in patients with diabetes.

Eur J Heart Fail 2017 01 21;19(1):43-53. Epub 2016 Sep 21.

Section of Endocrinology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1002/ejhf.633DOI Listing
January 2017

Implications of the EMPA-REG Trial for Clinical Care and Research.

Curr Diab Rep 2016 12;16(12):131

Section of Endocrinology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06520-8020, USA.

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http://dx.doi.org/10.1007/s11892-016-0822-7DOI Listing
December 2016

Citizen Petition to the US Food and Drug Administration to Change Prescribing Guidelines: The Metformin Experience.

Circulation 2016 11;134(18):1405-1408

From Section of Endocrinology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT (K.J.L., S.E.I.); Department of Healthcare Policy and Research, Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center, New York, NY (J.H.F.); and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (S.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.023041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147418PMC
November 2016

Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes.

N Engl J Med 2016 11;375(18):1801-2

University of Toronto, Toronto, ON, Canada

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http://dx.doi.org/10.1056/NEJMc1611290DOI Listing
November 2016

The IRIS (Insulin Resistance Intervention after Stroke) trial: A new perspective on pioglitazone.

J Diabetes 2016 Sep 8;8(5):607-9. Epub 2016 Jun 8.

Alpert Medical School, Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1111/1753-0407.12399DOI Listing
September 2016

Taking care of volunteers in a stroke trial: a new assisted-management strategy.

Stroke Vasc Neurol 2016 Sep 25;1(3):108-114. Epub 2016 Oct 25.

Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1136/svn-2016-000029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435205PMC
September 2016

Minimization of Hypoglycemia as an Adverse Event During Insulin Infusion: Further Refinement of the Yale Protocol.

Diabetes Technol Ther 2016 08 3;18(8):480-6. Epub 2016 Jun 3.

1 Pronia Medical Systems, LLC , Louisville, Kentucky.

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http://dx.doi.org/10.1089/dia.2016.0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991569PMC
August 2016

SGLT2 inhibitors in the management of type 2 diabetes.

Endocrine 2016 Aug 7;53(2):364-72. Epub 2016 Jun 7.

Department of Medicine, Section of Endocrinology, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1007/s12020-016-0943-4DOI Listing
August 2016

Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes.

N Engl J Med 2016 Jul 14;375(4):323-34. Epub 2016 Jun 14.

From the Department of Medicine, Division of Nephrology, Würzburg University Clinic, Würzburg (C.W.), and Boehringer Ingelheim Pharma, Ingelheim (M.E., M.M., H.J.W., U.C.B.) - both in Germany; the Section of Endocrinology, Yale University School of Medicine, New Haven, CT (S.E.I.); the Biostatistics Center, George Washington University, Rockville, MD (J.M.L.); the Divisions of Cardiology (D.F.) and Endocrinology (B.Z.), University of Toronto, and the Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital (B.Z.) - both in Toronto; and Boehringer Ingelheim Norway, Asker, Norway (O.E.J.).

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http://dx.doi.org/10.1056/NEJMoa1515920DOI Listing
July 2016

Autonomic dysfunction independently predicts poor cardiovascular outcomes in asymptomatic individuals with type 2 diabetes in the DIAD study.

SAGE Open Med 2015 24;3:2050312114568476. Epub 2015 Feb 24.

Section of Cardiovascular Medicine, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT, USA.

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http://dx.doi.org/10.1177/2050312114568476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679226PMC
April 2016

Pioglitazone after Ischemic Stroke or Transient Ischemic Attack.

N Engl J Med 2016 Apr 17;374(14):1321-31. Epub 2016 Feb 17.

From the School of Medicine (W.N.K., C.M.V., L.H.Y., S.E.I., A.M.L., L.M.B., J.R.O.) and the School of Public Health (P.D.G., P.N.P., J.R.O.), Yale University, New Haven, and the Cooperative Studies Program Coordinating Center, Veteran Affairs (VA) Connecticut HealthCare System, West Haven (P.D.G., P.N.P.) - all in Connecticut; Alpert Medical School, Brown University, Providence, RI (K.L.F.); Vermont College of Medicine, Burlington (M.G.); the National Institute of Neurological Disorders and Stroke, Bethesda, MD (R.C.); the VA Medical Center and the University of Colorado School of Medicine, Denver (G.G.S.); the University of Iowa, Iowa City (H.P.A.); Hôpital Charles LeMoyne, Greenfield Park, QC (L.B.), the University of Western Ontario, London (J.D.S.), and the Center for Neurological Research, Lethbridge, AB (T.R.W.) - all in Canada; University of L'Aquila, L'Aquila, Italy (A.C.); Oregon Health Sciences University, Portland (W.C.); the University of Arizona, Tucson (B.C.); the University of Oxford and Oxford University Hospitals NHS Foundation Trust, Oxfordshire, United Kingdom (G.A.F.); the University of Cincinnati, Cincinnati (D.K.); John Hunter Hospital, University of Newcastle, New Lambton Heights, NSW, Australia (M.W.P.); the University of Heidelberg, Heidelberg, Germany (P.R.); the University of South Carolina School of Medicine, Columbia (S.S.); Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel (D.T.); and the Illinois Neurological Institute-OSF Saint Francis Medical Center and the Department of Neurology, University of Illinois College of Medicine at Peoria, Peoria (D.W.).

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http://dx.doi.org/10.1056/NEJMoa1506930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887756PMC
April 2016

Current Therapies for the Medical Management of Diabetes.

Obstet Gynecol 2016 Apr;127(4):780-94

Department of Medicine, Section of Endocrinology, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1097/AOG.0000000000001332DOI Listing
April 2016

Metabolic Management during Critical Illness: Glycemic Control in the ICU.

Semin Respir Crit Care Med 2015 Dec 23;36(6):859-69. Epub 2015 Nov 23.

Department of Medicine, Section of Endocrinology and Metabolism, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1055/s-0035-1565253DOI Listing
December 2015