Publications by authors named "Silvia Novello"

100Publications

Adjuvant epidermal growth factor receptor tyrosine kinase inhibitors: are we actually ready?

Transl Lung Cancer Res 2020 Oct;9(5):1724-1727

Department of Oncology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy.

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http://dx.doi.org/10.21037/tlcr-20-545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653149PMC
October 2020

An examination of two dichotomies: Women with lung cancer and living with lung cancer as a chronic disease.

Respirology 2020 Nov 29;25 Suppl 2:24-36. Epub 2020 Oct 29.

GO2 Foundation for Lung Cancer, Washington, DC, USA.

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http://dx.doi.org/10.1111/resp.13965DOI Listing
November 2020

Patients With Lung Cancer and Coronavirus Disease 2019 Epidemic: An Experience From an Italian University Hospital.

JTO Clin Res Rep 2020 Sep 5;1(3):100067. Epub 2020 Jun 5.

Department of Clinical and Biological Sciences at San Luigi Hospital, University of Torino, Orbassano, Torino, Italy.

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http://dx.doi.org/10.1016/j.jtocrr.2020.100067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274095PMC
September 2020

KRAS inhibition in non-small cell lung cancer: Past failures, new findings and upcoming challenges.

Eur J Cancer 2020 Sep 31;137:57-68. Epub 2020 Jul 31.

Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.06.023DOI Listing
September 2020

New emerging targets in cancer immunotherapy: the role of VISTA.

ESMO Open 2020 Jun;4(Suppl 3)

Oncology Department, Thoracic Oncology, University of Turin & San Luigi Hospital, Orbassano (Turin), Italy.

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http://dx.doi.org/10.1136/esmoopen-2020-000683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305420PMC
June 2020

Double immune checkpoint blockade in advanced NSCLC.

Crit Rev Oncol Hematol 2020 Aug 19;152:102980. Epub 2020 May 19.

Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1016/j.critrevonc.2020.102980DOI Listing
August 2020

Anti-angiogenic agents in the age of resistance to immune checkpoint inhibitors: Do they have a role in non-oncogene-addicted non-small cell lung cancer?

Lung Cancer 2020 06 20;144:76-84. Epub 2020 Apr 20.

Boehringer Ingelheim International GmbH, Binger Strasse 173, 55216 Ingelheim am Rhein, Germany; Institute of Pharmacology, Johannes Gutenberg-University Mainz, 55122 Mainz, Germany.

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http://dx.doi.org/10.1016/j.lungcan.2020.04.009DOI Listing
June 2020

Expanding anaplastic lymphoma kinase therapeutic indication to early stage non-small cell lung cancer.

Transl Lung Cancer Res 2019 Nov;8(Suppl 3):S290-S297

Department of Oncology, University of Torino, Torino, Italy.

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http://dx.doi.org/10.21037/tlcr.2019.07.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894993PMC
November 2019

Patient-reported outcomes from FLAURA: Osimertinib versus erlotinib or gefitinib in patients with EGFR-mutated advanced non-small-cell lung cancer.

Eur J Cancer 2020 01 12;125:49-57. Epub 2019 Dec 12.

Department of Oncology, University of Turin, Azienda Ospedaliero-Universitaria San Luigi Gonzaga, Turin, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.11.006DOI Listing
January 2020

Oligometastatic non-small cell lung cancer (NSCLC): Does number of metastasis matter?

Lung Cancer 2020 01 13;139:216-218. Epub 2019 Nov 13.

Department of Pulmonary Diseases, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands; Department of Pulmonary Diseases, Erasmus Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.lungcan.2019.11.005DOI Listing
January 2020

Lung Cancer in Italy.

J Thorac Oncol 2019 12;14(12):2046-2052

Department of Oncology, University of Turin, San Luigi Hospital, Orbassano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.05.019DOI Listing
December 2019

EORTC Lung Cancer Group survey on the definition of NSCLC synchronous oligometastatic disease.

Eur J Cancer 2019 11 28;122:109-114. Epub 2019 Oct 28.

Department of Pulmonary Diseases, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Respiratory Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.09.012DOI Listing
November 2019

Five-year overall survival of pembrolizumab in advanced non-small cell lung cancer: another step from care to cure?

Ann Transl Med 2019 Sep;7(Suppl 6):S212

Department of Oncology, University of Torino, AOU S. Luigi Gonzaga, Orbassano, Italy.

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http://dx.doi.org/10.21037/atm.2019.08.91DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789333PMC
September 2019

Defining oligometastatic non-small cell lung cancer: A simulated multidisciplinary expert opinion.

Eur J Cancer 2019 12 23;123:28-35. Epub 2019 Oct 23.

Department of Pulmonary Diseases, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.09.013DOI Listing
December 2019

Current management of limited-stage SCLC and CONVERT trial impact: Results of the EORTC Lung Cancer Group survey.

Lung Cancer 2019 10 13;136:145-147. Epub 2019 Aug 13.

The University of Manchester, Division of Cancer Sciences, The Christie NHS Foundation Trust, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.lungcan.2019.08.007DOI Listing
October 2019

Defining Synchronous Oligometastatic Non-Small Cell Lung Cancer: A Systematic Review.

J Thorac Oncol 2019 12 11;14(12):2053-2061. Epub 2019 Jun 11.

Department of Intensive Care and Oncological Emergencies and Thoracic Oncology, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.jtho.2019.05.037DOI Listing
December 2019

Potential Diagnostic and Prognostic Role of Microenvironment in Malignant Pleural Mesothelioma.

J Thorac Oncol 2019 08 9;14(8):1458-1471. Epub 2019 May 9.

Department of Oncology, University of Torino, Torino, Italy; Interdepartmental Center "G. Scansetti" for the Study of Asbestos and Other Toxic Particulates, University of Torino, Torino, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.03.029DOI Listing
August 2019

Immunotherapy in first line for extensive-stage small-cell lung cancer: another piece is going to fill the puzzle?

Ann Transl Med 2018 Dec;6(Suppl 2):S120

Department of Oncology, University of Turin, San Luigi Hospital, Orbassano, Italy.

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http://dx.doi.org/10.21037/atm.2018.12.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330599PMC
December 2018

Advanced squamous lung cancer: therapeutic options, future directions, unmet needs and results of a monocentric survey.

Lung Cancer Manag 2017 Dec 1;6(3):93-107. Epub 2017 Dec 1.

Department of Oncology, University of Turin, San Luigi Hospital, Orbassano, Turin, Italy.

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https://www.futuremedicine.com/doi/10.2217/lmt-2017-0011
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http://dx.doi.org/10.2217/lmt-2017-0011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310352PMC
December 2017

Corrigendum to "Precision medicine in ALK rearranged NSCLC: A rapidly evolving scenario" [Crit. Rev. Oncol./Hematol. 122 (February) (2018) 150-156].

Crit Rev Oncol Hematol 2019 Jul 2;139:158. Epub 2018 Nov 2.

Oncology Department, San Luigi Hospital University of Turin, Orbassano, Turin, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S10408428183028
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http://dx.doi.org/10.1016/j.critrevonc.2018.06.018DOI Listing
July 2019

Pembrolizumab plus Chemotherapy for Squamous Non-Small-Cell Lung Cancer.

N Engl J Med 2018 11 25;379(21):2040-2051. Epub 2018 Sep 25.

From Hospital Universitario 12 de Octubre, Spanish National Cancer Research Center, Universidad Complutense and Ciberonc, Madrid (L.P.-A.), and Hospital Universitario Virgen Macarena, Seville (D.V.) - both in Spain; Leningrad Regional Clinical Hospital, St. Petersburg, Russia (A.L.); Wollongong Oncology and Wollongong Private Hospital, Wollongong, NSW, Australia (A.T.); Istanbul Medeniyet University Hospital, Istanbul (M.G.), and Ankara University, Ankara (F.Ç.Ş.) - both in Turkey; Centre Hospitalier Universitaire de Toulouse, Université Paul Sabatier, Toulouse, France (J.M.); Universitätsklinikum Tübingen, Tübingen, Germany (B. Hermes); Jász-Nagykun-Szolnok County Hospital, Szolnok (T.C.), and Országos Korányi TBC és Pulmonológiai Intézet, Budapest (A.F.) - both in Hungary; Oncology Center, Medica Sur Hospital, Mexico City (J.R.-C.); Humber River Regional Hospital, Toronto (J.W.); Sendai Kousei Hospital, Sendai (S.S.), and the Kanagawa Cancer Center, Yokohama (T.K.) - both in Japan; Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheong-ju, South Korea (K.H.L.); Jilin Cancer Hospital, Changchun, China (Y.C.); University of Turin, Orbassano, Italy (S.N.); Montefiore Medical Center-Albert Einstein College of Medicine, New York (B. Halmos); Merck, Kenilworth, NJ (X.L., G.M.L., B.P.); and the Maria Skłodowska-Curie Institute of Oncology, Warsaw, Poland (D.M.K.).

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http://dx.doi.org/10.1056/NEJMoa1810865DOI Listing
November 2018

A Brief Report of Transformation From NSCLC to SCLC: Molecular and Therapeutic Characteristics.

J Thorac Oncol 2019 01 11;14(1):130-134. Epub 2018 Sep 11.

Thoracic Oncology unit, PTV, CHU Grenoble CS10217-38043 Grenoble cedex 9, France et INSERM U 823. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.08.2028DOI Listing
January 2019

Management of Leptomeningeal Metastases in Non-oncogene Addicted Non-small Cell Lung Cancer.

Front Oncol 2018 27;8:278. Epub 2018 Jul 27.

Department of Oncology, University of Torino, Ospedale San Luigi Gonzaga, Orbassano, Italy.

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https://www.frontiersin.org/article/10.3389/fonc.2018.00278/
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http://dx.doi.org/10.3389/fonc.2018.00278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094962PMC
July 2018

Alectinib in the treatment of ALK-positive non-small cell lung cancer: an update on its properties, efficacy, safety and place in therapy.

Ther Adv Med Oncol 2018 3;10:1758835918789364. Epub 2018 Aug 3.

Department of Oncology, University of Torino, AOU S. Luigi Gonzaga, Regione Gonzole 10, Orbassano (TO), Turin, Orbassano 10043, Italy.

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http://dx.doi.org/10.1177/1758835918789364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077883PMC
August 2018

Immunotherapy & thoracic cancers.

J Thorac Dis 2018 May;10(Suppl 13):S1425-S1426

Department of Oncology, University of Turin, Azienda Ospedaliero-Universitaria San Luigi Gonzaga, Orbassano (TO), Italy. (Email:

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http://dx.doi.org/10.21037/jtd.2017.12.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994492PMC
May 2018

Patient-Reported Symptoms and Impact of Treatment With Osimertinib Versus Chemotherapy in Advanced Non-Small-Cell Lung Cancer: The AURA3 Trial.

J Clin Oncol 2018 06 7;36(18):1853-1860. Epub 2018 May 7.

Chee Khoon Lee, St George Hospital, Kogarah, New South Wales, Australia; Silvia Novello, University of Turin, Turin, Italy; Anna Rydén, AstraZeneca Gothenburg, Mölndal, Sweden; Helen Mann, AstraZeneca R&D, Cambridge, United Kingdom; and Tony Mok, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Special Administrative Region, People's Republic of China.

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http://ascopubs.org/doi/10.1200/JCO.2017.77.2293
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http://dx.doi.org/10.1200/JCO.2017.77.2293DOI Listing
June 2018

The Tradition of the Rising Sun: When Geography Counts.

J Thorac Oncol 2018 05;13(5):598-600

University of Turin, Department of Oncology, San Luigi Hospital, Orbassano, Turin, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.03.006DOI Listing
May 2018

Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.

N Engl J Med 2018 May 16;378(22):2078-2092. Epub 2018 Apr 16.

From NYU Perlmutter Cancer Center, New York (L.G.); Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria (D.R.-A.), Hospital Universitario Central de Asturias, Oviedo (E.E.), Vall d'Hebron University, Vall d'Hebron Institute of Oncology, Barcelona (E.F.), and Fundación Jiménez Díaz (M.D.) and Hospital Universitario Quirón Madrid (B.R.-V.), Madrid - all in Spain; Karmanos Cancer Institute, Detroit (S.G.); Integrated Health and Social Services Centres, Montérégie Centre, Greenfield Park, QC (F.D.A.), and Sunnybrook Health Sciences Centre, Toronto (S.Y.-S.C.) - both in Canada; Southern Medical Day Care Centre, Wollongong, NSW (P.C.), Epworth Healthcare, Richmond, VIC (R.R.J.), Westmead Hospital and University of Sydney, Sydney (R.H.), and Chris O'Brien Lifehouse, Camperdown, NSW (M.B.) - all in Australia; Otto Wagner Hospital, Vienna (M.J.H.); Sanford Health, Sioux Falls, SD (S.F.P.); Thoraxklinik, Heidelberg (H.G.B.), and LungenClinic, Airway Research Center North, German Center for Lung Research, Grosshansdorf (M.R.) - both in Germany; Davidoff Cancer Center, Tel Aviv University, Petah Tikva, Israel (N.P.); Ospedale Policlinico San Martino, Genoa (F.G.), University of Turin, Azienda Ospedaliero-Universitaria San Luigi, Orbassano (S.N.), and Fondazione IRCCS Istituto Nazionale dei Tumori, Milan (M.C.G.) - all in Italy; David Geffen School of Medicine at UCLA, Los Angeles (E.B.G.); Kansai Medical University Hospital, Osaka, Japan (T.K.); Moffitt Cancer Center, Tampa, FL (J.E.G.); and Merck, Kenilworth, NJ (J.V., Z.W., J.Y., H.R., M.C.P.).

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http://dx.doi.org/10.1056/NEJMoa1801005DOI Listing
May 2018

Precision medicine in ALK rearranged NSCLC: A rapidly evolving scenario.

Crit Rev Oncol Hematol 2018 Feb 30;122:150-156. Epub 2017 Dec 30.

Oncology Department, San Luigi Hospital University of Turin, Orbassano, Turin, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2017.12.015DOI Listing
February 2018

Nintedanib Plus Pemetrexed/Cisplatin in Patients With Malignant Pleural Mesothelioma: Phase II Results From the Randomized, Placebo-Controlled LUME-Meso Trial.

J Clin Oncol 2017 Nov 11;35(31):3591-3600. Epub 2017 Sep 11.

Federica Grosso, Azienda Ospedaliera SS Antonio e Biagio General Hospital, Alessandria; Silvia Novello and Giorgio Scagliotti, L'università di Torino, Azienda Sanitaria Ospedale San Luigi Gonzaga, Turin, Italy; Anna K. Nowak, University of Western Australia, Crawley, and Sir Charles Gairdner Hospital, Nedlands, Western Australia; Thomas John, Olivia Newton-John Cancer Research Institute, Austin Hospital, Heidelberg, Victoria, Australia; Sanjay Popat, The Royal Marsden Hospital National Health Service (NHS) Foundation Trust, London; Nicola Steele, The Beatson West of Scotland Cancer Centre, Glasgow; Paul Taylor, University Hospitals of South Manchester NHS Trust, Wythenshawe, Manchester, United Kingdom; Laurent Greillier, Assitance Publique Hôpitaux de Marseille, Aix Marseille University, Marseille; David Planchard, Institut Gustave Roussy, Villejuif; Nassim Morsli, Boehringer Ingelheim France S.A.S., Paris, France; Natasha B. Leighl, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Martin Reck, Lung Clinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf; Ute von Wangenheim, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany; Jens Benn Sørensen, Rigshospitalet - Finsencentret, Copenhagen, Denmark; Mark A. Socinski, Florida Hospital Cancer Institute, Orlando, FL; Arsène Bienvenu Loembé, Boehringer Ingelheim B.V., Alkmaar, the Netherlands; and José Barrueco, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT.

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http://dx.doi.org/10.1200/JCO.2017.72.9012DOI Listing
November 2017

Efficacy and Safety of Nintedanib Plus Docetaxel in Patients with Advanced Lung Adenocarcinoma: Complementary and Exploratory Analyses of the Phase III LUME-Lung 1 Study.

Target Oncol 2017 08;12(4):475-485

Department of Thoracic Oncology, LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), 22927, Grosshansdorf, Germany.

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http://dx.doi.org/10.1007/s11523-017-0517-2DOI Listing
August 2017

Interview: developing therapies for lung cancer.

Authors:
Silvia Novello

Lung Cancer Manag 2017 Jul 14;6(1):25-27. Epub 2017 Jul 14.

Department of Oncology, San Luigi Hospital, University of Turin, Orbassano, Turin, Italy.

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http://dx.doi.org/10.2217/lmt-2017-0007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310310PMC
July 2017

Targeted therapy in small cell lung cancer: A new era?

Lung Cancer 2017 06 12;108:252-253. Epub 2017 Mar 12.

Department of Oncology, University of Turin, Italy.

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http://dx.doi.org/10.1016/j.lungcan.2017.03.004DOI Listing
June 2017

Osimertinib in Pretreated T790M-Positive Advanced Non-Small-Cell Lung Cancer: AURA Study Phase II Extension Component.

J Clin Oncol 2017 Apr 21;35(12):1288-1296. Epub 2017 Feb 21.

James Chih-Hsin Yang and Chia-Chi Lin, National Taiwan University Hospital, Taipei; Wu-Chou Su, National Cheng Kung University Hospital, Tainan, Taiwan, Republic of China; Myung-Ju Ahn, Sungkyunkwan University; Dong-Wan Kim, Seoul National University Hospital; Sang-We Kim, Asan Medical Center, Seoul; Joo-Hang Kim, CHA University, Gyeonggi-do, Republic of Korea; Suresh S. Ramalingam, Emory University School of Medicine, Atlanta, GA; Lecia V. Sequist, Massachusetts General Hospital; Pasi A. Jänne, Dana-Farber Cancer Institute, Boston, MA; David Planchard, Institut Gustave Roussy, Villejuif, France; Enriqueta Felip, Vall d'Hebron University Hospital, Barcelona, Spain; Fiona Blackhall, The Christie Hospital; University of Manchester, Manchester; Helen Mann and Serban Ghiorghiu, AstraZeneca, Cambridge; Mireille Cantarini, AstraZeneca, Macclesfield, United Kingdom; Daniel Haggstrom, Carolinas Healthcare System, Charlotte, NC; Kiyotaka Yoh, National Cancer Center Hospital East, Kashiwa, Chiba; Tomonori Hirashima, Osaka Prefectural Medical Center for Respiratory and Allergic Diseases, Osaka, Japan; Silvia Novello, University of Turin, Turin, Italy; and Kathryn Gold, University of California San Diego Moores Cancer Center, San Diego, CA.

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http://ascopubs.org/doi/10.1200/JCO.2016.70.3223
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http://dx.doi.org/10.1200/JCO.2016.70.3223DOI Listing
April 2017

Fatigue in lung cancer patients: symptom burden and management of challenges.

Lung Cancer (Auckl) 2016 9;7:73-82. Epub 2016 May 9.

Oncology Department, University of Turin, AOU San Luigi, Orbassano, Italy.

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http://dx.doi.org/10.2147/LCTT.S85334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310693PMC
May 2016

Anti-angiogenetic therapies for central nervous system metastases from non-small cell lung cancer.

Transl Lung Cancer Res 2016 Dec;5(6):610-627

Department of Oncology, San Luigi Hospital, University of Turin, Orbassano, Turin, Italy.

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http://dx.doi.org/10.21037/tlcr.2016.09.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233881PMC
December 2016

Helical-Tip Needle for Transthoracic Percutaneous Image-Guided Biopsy of Lung Tumors: Results of a Pilot Prospective Comparative Study with a Standard Tru-Cut Needle.

Cardiovasc Intervent Radiol 2017 Jun 26;40(6):930-936. Epub 2017 Jan 26.

Department of Pathology, San Luigi Gonzaga Hospital, University of Torino, Regione Gonzole 10, 10043, Orbassano, Turin, Italy.

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http://dx.doi.org/10.1007/s00270-017-1585-5DOI Listing
June 2017

Intercalated Chemotherapy and Epidermal Growth Factor Receptor Inhibitors for Patients With Advanced Non-Small-cell Lung Cancer: A Systematic Review and Meta-analysis.

Clin Lung Cancer 2017 01 28;18(1):23-33.e1. Epub 2016 Oct 28.

Department of Oncology, University of Turin, "San Luigi Gonzaga" Hospital, Orbassano, Italy.

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http://dx.doi.org/10.1016/j.cllc.2016.08.006DOI Listing
January 2017