Silvia Murillo-Cuesta

The Value of Mouse Models of Rare Diseases: A Spanish Experience.

Authors:

Silvia Murillo-Cuesta Rafael Artuch Fernando Asensio Pedro de la Villa Mara Dierssen Jose Antonio Enríquez Cristina Fillat Stéphane Fourcade Borja Ibáñez Lluis Montoliu Eduardo Oliver Aurora Pujol Eduardo Salido Mario Vallejo Isabel Varela-Nieto

Front Genet 2020 14;11:583932. Epub 2020 Oct 14.

Biomedical Research Networking Center on Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain.

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October 2020

Drug development for noise-induced hearing loss.

Authors:

Isabel Varela-Nieto Silvia Murillo-Cuesta Miryam Calvino Rafael Cediel Luis Lassaletta

Expert Opin Drug Discov 2020 Dec 25;15(12):1457-1471. Epub 2020 Aug 25.

Institute for Biomedical Research "Alberto Sols" CSIC-UAM , Madrid, Spain.

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December 2020

Solid Lipid Nanoparticles Loaded with Glucocorticoids Protect Auditory Cells from Cisplatin-Induced Ototoxicity.

Authors:

Blanca Cervantes Lide Arana Silvia Murillo-Cuesta Marina Bruno Itziar Alkorta Isabel Varela-Nieto

J Clin Med 2019 Sep 14;8(9). Epub 2019 Sep 14.

Institute for Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM), 28029 Madrid, Spain.

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September 2019

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.

Authors:

Adelaida M Celaya Isabel Sánchez-Pérez Jose M Bermúdez-Muñoz Lourdes Rodríguez-de la Rosa Laura Pintado-Berninches Rosario Perona Silvia Murillo-Cuesta Isabel Varela-Nieto

Elife 2019 04 2;8. Epub 2019 Apr 2.

Institute for Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM), Madrid, Spain.

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April 2019

Betaine-homocysteine -methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia.

Authors:

Teresa Partearroyo Silvia Murillo-Cuesta Néstor Vallecillo Jose M Bermúdez-Muñoz Lourdes Rodríguez-de la Rosa Giacomo Mandruzzato Adelaida M Celaya Steven H Zeisel María A Pajares Gregorio Varela-Moreiras Isabel Varela-Nieto

FASEB J 2019 05 12;33(5):5942-5956. Epub 2019 Feb 12.

Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain.

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May 2019

MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse.

Am J Hum Genet 2018 07 28;103(1):74-88. Epub 2018 Jun 28.

Hearing and Genes Division, Department of Otorhinolaryngology, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands. Electronic address:

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July 2018

Mutations in L-type amino acid transporter-2 support as a novel gene involved in age-related hearing loss.

Authors:

Meritxell Espino Guarch Mariona Font-Llitjós Silvia Murillo-Cuesta Ekaitz Errasti-Murugarren Adelaida M Celaya Giorgia Girotto Dragana Vuckovic Massimo Mezzavilla Clara Vilches Susanna Bodoy Ignasi Sahún Laura González Esther Prat Antonio Zorzano Mara Dierssen Isabel Varela-Nieto Paolo Gasparini Manuel Palacín Virginia Nunes

Elife 2018 01 22;7. Epub 2018 Jan 22.

Genes, Disease and Therapy Program, Molecular Genetics Laboratory - IDIBELL, Barcelona, Spain.

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January 2018

The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss.

Authors:

Lourdes Rodríguez-de la Rosa Luis Lassaletta Miryam Calvino Silvia Murillo-Cuesta Isabel Varela-Nieto

Front Aging Neurosci 2017 12;9:411. Epub 2017 Dec 12.

"Alberto Sols" Biomedical Research Institute CSIC-UAM, Madrid, Spain.

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December 2017

The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea.

Authors:

Fernando García-Alcántara Silvia Murillo-Cuesta Sara Pulido Jose M Bermúdez-Muñoz Raquel Martínez-Vega Marta Milo Isabel Varela-Nieto Teresa Rivera

Hear Res 2018 02 14;358:10-21. Epub 2017 Dec 14.

Príncipe de Asturias University Hospital, Universidad de Alcalá, Carretera Alcalá-Meco s/n, 28805, Alcalá de Henares, Madrid, Spain; Institute of Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM), Arturo Duperier 4, 28029, Madrid, Spain; Centre for Biomedical Network Research in Rare Diseases (CIBERER), Institute of Health Carlos III (ISCIII), Monforte de Lemos, 3-5, 28029, Madrid, Spain. Electronic address:

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February 2018

A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection.

Authors:

Silvia Murillo-Cuesta Néstor Vallecillo Rafael Cediel Adelaida M Celaya Luis Lassaletta Isabel Varela-Nieto Julio Contreras

J Vis Exp 2017 03 8(121). Epub 2017 Mar 8.

Instituto de Investigaciones Biomédicas (IIBm) Alberto Sols CSIC-UAM; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III (ISCIII); Facultad de Veterinaria, Universidad Complutense de Madrid.

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March 2017

Long-Term Dietary Folate Deficiency Accelerates Progressive Hearing Loss on CBA/Ca Mice.

Authors:

Raquel Martínez-Vega Silvia Murillo-Cuesta Teresa Partearroyo Gregorio Varela-Moreiras Isabel Varela-Nieto María A Pajares

Front Aging Neurosci 2016 31;8:209. Epub 2016 Aug 31.

Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM)Madrid, Spain; Instituto de Investigación Hospital Universitario La Paz (IdiPAZ)Madrid, Spain.

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September 2016

Autophagy resolves early retinal inflammation in Igf1-deficient mice.

Authors:

Ana I Arroba Lourdes Rodríguez-de la Rosa Silvia Murillo-Cuesta Laura Vaquero-Villanueva Juan M Hurlé Isabel Varela-Nieto Ángela M Valverde

Dis Model Mech 2016 09 21;9(9):965-74. Epub 2016 Jul 21.

Alberto Sols Biomedical Research Institute (IIBm) (CSIC/UAM), 28029, Madrid, Spain Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERdem), ISCIII, 28029, Madrid, Spain IdiPAZ Institute for Health Research, Madrid 28029, Spain

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September 2016

Comparative gene expression study of the vestibular organ of the Igf1 deficient mouse using whole-transcript arrays.

Authors:

Lourdes Rodríguez-de la Rosa Hortensia Sánchez-Calderón Julio Contreras Silvia Murillo-Cuesta Sandra Falagan Carlos Avendaño Joaquín Dopazo Isabel Varela-Nieto Marta Milo

Hear Res 2015 Dec 1;330(Pt A):62-77. Epub 2015 Sep 1.

Department of Biomedical Science, University of Sheffield, Sheffield, UK. Electronic address:

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December 2015

Corrigendum to: Swept-sine noise-induced damage as a hearing loss model for preclinical assays.

Authors:

Lorena Sanz Silvia Murillo-Cuesta Pedro Cobo Rafael Cediel Julio Contreras Teresa Rivera Isabel Varela-Nieto Carlos Avendaño

Front Aging Neurosci 2015 12;7:79. Epub 2015 May 12.

Department of Anatomy, Histology and Neuroscience, Medical School, Autónoma University of Madrid Madrid, Spain.

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June 2015

Corrigendum: Transforming growth factor β1 inhibition protects from noise-induced hearing loss.

Authors:

Silvia Murillo-Cuesta Lourdes Rodríguez-de la Rosa Julio Contreras Adelaida M Celaya Guadalupe Camarero Teresa Rivera Isabel Varela-Nieto

Front Aging Neurosci 2015 8;7:72. Epub 2015 May 8.

Institute of Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM) Madrid, Spain ; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Institute of Health Carlos III (ISCIII) Madrid, Spain ; Hospital La Paz Institute for Health Research (IdiPAZ) Madrid, Spain.

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May 2015

Transforming growth factor β1 inhibition protects from noise-induced hearing loss.

Authors:

Silvia Murillo-Cuesta Lourdes Rodríguez-de la Rosa Julio Contreras Adelaida M Celaya Guadalupe Camarero Teresa Rivera Isabel Varela-Nieto

Front Aging Neurosci 2015 20;7:32. Epub 2015 Mar 20.

Institute for Biomedical Research "Alberto Sols" (IIBM), Spanish National Research Council-Autonomous University of Madrid (CSIC-UAM) Madrid, Spain ; Centre for Biomedical Network Research (CIBER), Institute of Health Carlos III (ISCIII) Madrid, Spain ; Hospital La Paz Institute for Health Research (IdiPAZ) Madrid, Spain.

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April 2015

Swept-sine noise-induced damage as a hearing loss model for preclinical assays.

Authors:

Lorena Sanz Silvia Murillo-Cuesta Pedro Cobo Rafael Cediel-Algovia Julio Contreras Teresa Rivera Isabel Varela-Nieto Carlos Avendaño

Front Aging Neurosci 2015 16;7. Epub 2015 Feb 16.

Hospital La Paz Institute for Health Research (IdiPAZ) Madrid, Spain ; Department of Anatomy, Histology and Neuroscience, Medical School, Autónoma University of Madrid Madrid, Spain.

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March 2015

Treatment with N- and C-terminal peptides of parathyroid hormone-related protein partly compensate the skeletal abnormalities in IGF-I deficient mice.

Authors:

Lourdes Rodríguez-de la Rosa Ana López-Herradón Sergio Portal-Núñez Silvia Murillo-Cuesta Daniel Lozano Rafael Cediel Isabel Varela-Nieto Pedro Esbrit

PLoS One 2014 4;9(2):e87536. Epub 2014 Feb 4.

Laboratorio de Metabolismo Mineral y Óseo, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, Madrid, Spain ; Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad, Instituto de Salud Carlos III, Madrid, Spain.

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December 2014