Publications by authors named "Silvia Di Agostino"

44Publications

A Division of Labor between YAP and TAZ in Non-Small Cell Lung Cancer.

Cancer Res 2020 Oct 14;80(19):4145-4157. Epub 2020 Aug 14.

Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1158/0008-5472.CAN-20-0125DOI Listing
October 2020

Circular RNAs in Embryogenesis and Cell Differentiation With a Focus on Cancer Development.

Front Cell Dev Biol 2020 27;8:389. Epub 2020 May 27.

Department of Anatomical, Histological, Forensic & Orthopedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.3389/fcell.2020.00389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266935PMC
May 2020

The Impact of Mutant p53 in the Non-Coding RNA World.

Biomolecules 2020 03 19;10(3). Epub 2020 Mar 19.

IRCCS Regina Elena National Cancer Institute-IFO, Oncogenomic and Epigenetic Unit; via Elio Chianesi, 53-00144 Rome, Italy.

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http://dx.doi.org/10.3390/biom10030472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175150PMC
March 2020

Arenavirus as a potential etiological agent of odontogenic tumours in humans.

J Exp Clin Cancer Res 2020 Feb 10;39(1):34. Epub 2020 Feb 10.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, 00144, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-020-1540-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011367PMC
February 2020

The miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas.

Cancers (Basel) 2019 09 11;11(9). Epub 2019 Sep 11.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.

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http://dx.doi.org/10.3390/cancers11091347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771082PMC
September 2019

Targeting mutant p53 in cancer: the latest insights.

J Exp Clin Cancer Res 2019 Jul 5;38(1):290. Epub 2019 Jul 5.

Department of Medical Science, University 'G. D'Annunzio, 66013, Chieti, Italy.

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http://dx.doi.org/10.1186/s13046-019-1302-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612074PMC
July 2019

Wild type- and mutant p53 proteins in mitochondrial dysfunction: emerging insights in cancer disease.

Semin Cell Dev Biol 2020 02 23;98:105-117. Epub 2019 May 23.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, Rome, 00144, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2019.05.011DOI Listing
February 2020

Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma.

Theranostics 2018 12;8(7):1850-1868. Epub 2018 Feb 12.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, Rome 00144, Italy.

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http://dx.doi.org/10.7150/thno.22167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858504PMC
February 2019

New therapeutic strategies to treat human cancers expressing mutant p53 proteins.

J Exp Clin Cancer Res 2018 Feb 15;37(1):30. Epub 2018 Feb 15.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, 00144, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-018-0705-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815234PMC
February 2018

MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer.

Carcinogenesis 2017 01 17;38(1):64-75. Epub 2016 Oct 17.

Department of Life Sciences, Center for Genome Research, University of Modena and Reggio Emilia, via G. Campi 287, 41100 Modena, Italy.

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http://dx.doi.org/10.1093/carcin/bgw110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276925PMC
January 2017

Oncogenic Intra-p53 Family Member Interactions in Human Cancers.

Front Oncol 2016 31;6:77. Epub 2016 Mar 31.

Molecular Chemoprevention Unit, Department of Molecular Medicine, Regina Elena National Cancer Institute , Rome , Italy.

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http://dx.doi.org/10.3389/fonc.2016.00077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814729PMC
April 2016

YAP enhances the pro-proliferative transcriptional activity of mutant p53 proteins.

EMBO Rep 2016 Feb 21;17(2):188-201. Epub 2015 Dec 21.

Translational Oncogenomic Unit, Molecular Medicine Area Regina Elena National Cancer Institute, Rome, Italy

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http://dx.doi.org/10.15252/embr.201540488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290815PMC
February 2016

Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine.

Biochim Biophys Acta 2015 Jan 13;1853(1):89-100. Epub 2014 Oct 13.

Department of Life and Reproduction Sciences, Biochemistry Section, University of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2014.10.003DOI Listing
January 2015

Interaction of mutant p53 with p73: a Surface Plasmon Resonance and Atomic Force Spectroscopy study.

Biochim Biophys Acta 2014 Jun 24;1840(6):1958-64. Epub 2014 Feb 24.

Biophysics and Nanoscience Centre, CNISM, Dipartimento DEB, Università della Tuscia, Viterbo, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03044165140007
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http://dx.doi.org/10.1016/j.bbagen.2014.02.014DOI Listing
June 2014

Gender, mutant p53 and PML: a growing "affaire" in tumor suppression and oncogenesis.

Cell Cycle 2013 Jun 5;12(12):1824-5. Epub 2013 Jun 5.

Translational Oncogenomics Laboratory, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.4161/cc.25174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735694PMC
June 2013

PML Surfs into HIPPO Tumor Suppressor Pathway.

Front Oncol 2013 1;3:36. Epub 2013 Mar 1.

Molecular Chemoprevention Group, Molecular Medicine Area, Regina Elena National Cancer Institute Rome, Italy.

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http://dx.doi.org/10.3389/fonc.2013.00036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585432PMC
March 2013

Hippo and rassf1a Pathways: A Growing Affair.

Mol Biol Int 2012 5;2012:307628. Epub 2012 Jul 5.

Molecular Chemoprevention Group, Molecular Medicine Area, Regina Elena Cancer Institute, Via Elio Chianesi 53, 00143 Rome, Italy.

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http://dx.doi.org/10.1155/2012/307628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399428PMC
August 2012

Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop.

Cell Cycle 2011 Dec 15;10(24):4330-40. Epub 2011 Dec 15.

Translational Oncogenomics Unit, Regina Elena Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.4161/cc.10.24.18682DOI Listing
December 2011

The cancer-associated K351N mutation affects the ubiquitination and the translocation to mitochondria of p53 protein.

J Biol Chem 2011 Nov 27;286(46):39693-702. Epub 2011 Sep 27.

Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Biology and Biotechnology, Sapienza University, 00185-Rome, Italy.

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http://dx.doi.org/10.1074/jbc.M111.279539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220532PMC
November 2011

Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain.

Cell Cycle 2009 Oct 24;8(20):3396-405. Epub 2009 Oct 24.

Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Cellular Biology and Development, Sapienza University, Italy.

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http://dx.doi.org/10.4161/cc.8.20.9910DOI Listing
October 2009

A combined atomic force microscopy imaging and docking study to investigate the complex between p53 DNA binding domain and Azurin.

J Mol Recognit 2009 Nov-Dec;22(6):506-15

Biophysics & Nanoscience Centre, CNISM, Facolta' di Scienze, Università della Tuscia, I-01100 Viterbo, Italy.

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http://dx.doi.org/10.1002/jmr.975DOI Listing
February 2010

Promyelocytic leukemia protein is required for gain of function by mutant p53.

Cancer Res 2009 Jun;69(11):4818-26

Research Division, The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-08-4010DOI Listing
June 2009

PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.

Mol Cell 2008 Dec;32(6):803-14

Ludwig Institute for Cancer Research, University of Oxford Branch, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1016/j.molcel.2008.11.019DOI Listing
December 2008

The disruption of the protein complex mutantp53/p73 increases selectively the response of tumor cells to anticancer drugs.

Cell Cycle 2008 Nov 16;7(21):3440-7. Epub 2008 Nov 16.

Pharmacocinetic and Animal Models Unit, Regina Elena Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.4161/cc.7.21.6995DOI Listing
November 2008

Mutant p53 proteins: between loss and gain of function.

Head Neck 2007 May;29(5):488-96

Department of Experimental Oncology, Regina Elena Cancer Institute, 00158 Rome, Italy.

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http://dx.doi.org/10.1002/hed.20531DOI Listing
May 2007

Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation.

Cancer Cell 2006 Sep;10(3):191-202

Experimental Oncology Department, Istituto Regina Elena, Via delle Messi D'Oro 156, 00158 Rome, Italy.

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http://dx.doi.org/10.1016/j.ccr.2006.08.013DOI Listing
September 2006

17-beta-estradiol elicits genomic and non-genomic responses in mouse male germ cells.

J Cell Physiol 2006 Jan;206(1):238-45

Department of Histology and Medical Embriology, University of Rome La Sapienza, Rome, Italy.

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http://dx.doi.org/10.1002/jcp.20454DOI Listing
January 2006

Meiotic progression of isolated mouse spermatocytes under simulated microgravity.

Reproduction 2004 Jul;128(1):25-32

Dipartimento di Sanità Pubblica e Biologia Cellulare, Università di Roma 'Tor Vergata', Via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1530/rep.1.00184DOI Listing
July 2004

Analysis of the gene expression profile of mouse male meiotic germ cells.

Gene Expr Patterns 2004 May;4(3):267-81

Dipartimento di Sanita Pubblica e Biologia Cellulare, Sezione di Anatomia, Universita di Roma Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.modgep.2003.11.003DOI Listing
May 2004

Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes.

Mol Biol Cell 2004 Mar 10;15(3):1224-32. Epub 2003 Dec 10.

Dipartimento di Sanità Pubblica e Biologia Cellulare, University of Rome "Tor Vergata," 00133 Rome, Italy.

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http://dx.doi.org/10.1091/mbc.e03-09-0638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC363112PMC
March 2004

Prolin-rich tyrosine kinase 2 (PYK2) expression and localization in mouse testis.

Mol Reprod Dev 2003 Jul;65(3):330-5

Dipartimento di Medicina Sperimentale, II Università di Napoli, Naples, Italy.

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http://doi.wiley.com/10.1002/mrd.10297
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http://dx.doi.org/10.1002/mrd.10297DOI Listing
July 2003

The mechanism of docosahexaenoic acid-induced phospholipase D activation in human lymphocytes involves exclusion of the enzyme from lipid rafts.

J Biol Chem 2002 Oct 24;277(42):39368-78. Epub 2002 Jul 24.

Unité INSERM 352, Laboratoire de Biochimie et Pharmacologie, INSA de Lyon, 69621 Villeurbanne, France.

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http://dx.doi.org/10.1074/jbc.M202376200DOI Listing
October 2002

HMGA1 and HMGA2 protein expression in mouse spermatogenesis.

Oncogene 2002 May;21(22):3644-50

Dipartimento di Medicina Sperimentale, II Università di Napoli, via Costantinopoli 16, 80138 Naples, Italy.

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http://dx.doi.org/10.1038/sj.onc.1205501DOI Listing
May 2002

The MAPK pathway triggers activation of Nek2 during chromosome condensation in mouse spermatocytes.

Development 2002 Apr;129(7):1715-27

Dipartimento di Sanità Pubblica e Biologia Cellulare, Facoltà di Medicina e Chirurgia, Università di Roma Tor Vergata, Via O. Raimondo 8, 00173 Rome, Italy.

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April 2002