Publications


Hydroxychloroquine and joint involvement in systemic sclerosis: Preliminary beneficial results from a retrospective case-control series of an EUSTAR center.
Joint Bone Spine 2017 Dec 5;84(6):747-748. Epub 2016 Dec 5.
Department of Experimental and Clinical Medicine, University of Florence, Viale Gaetano Pieraccini 18, 50134 Florence, Italy; Department of Geriatric Medicine, Division of Rheumatology AOUC, University of Florence, Viale Gaetano Pieraccini 18, 50134 Florence, Italy.

The "myth" of loss of angiogenesis in systemic sclerosis: a pivotal early pathogenetic process or just a late unavoidable event?
Arthritis Res Ther 2017 Jul 6;19(1):162. Epub 2017 Jul 6.
Department of Experimental and Clinical Medicine, Division of Rheumatology and Scleroderma Unit, Azienda Ospedaliera Universitaria Careggi, University of Florence, Viale Pieraccini 18, 50139, Florence, Italy.

Endothelial-to-mesenchymal transition contributes to endothelial dysfunction and dermal fibrosis in systemic sclerosis.
Ann Rheum Dis 2017 May 6;76(5):924-934. Epub 2017 Jan 6.
Department of Experimental and Clinical Medicine, Section of Internal Medicine, Rheumatology Unit, Azienda Ospedaliero-Universitaria Careggi (AOUC), University of Florence, Florence, Italy.

Proangiogenic effects of soluble α-Klotho on systemic sclerosis dermal microvascular endothelial cells.
Arthritis Res Ther 2017 Feb 10;19(1):27. Epub 2017 Feb 10.
Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, AOUC, Largo Brambilla 3, 50134, Florence, Italy.

Decreased expression of neuropilin-1 as a novel key factor contributing to peripheral microvasculopathy and defective angiogenesis in systemic sclerosis.
Ann Rheum Dis 2016 Aug 10;75(8):1541-9. Epub 2015 Sep 10.
Department of Experimental and Clinical Medicine, Division of Rheumatology, Azienda Ospedaliero-Universitaria Careggi (AOUC), University of Florence, Florence, Italy.


Assessment, Definition, and Classification of Lower Limb Ulcers in Systemic Sclerosis: A Challenge for the Rheumatologist.
J Rheumatol 2016 Mar 1;43(3):592-8. Epub 2016 Feb 1.
From the University of Florence: Department of Clinical and Experimental Medicine, Division of Rheumatology; Department of Internal Medicine; Interinstitutional Department of Didactics, Florence, Italy.J. Blagojevic, MD, Doctoral Candidate, University of Siena and University of Florence Joint Doctoral Program, Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Florence; G. Piemonte, BSN, RN, Doctoral Candidate, University of Florence, Department of Clinical and Experimental Medicine, Division of Rheumatology; L. Benelli, BSN, RN, Registered Nurse, Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Florence; F. Braschi, BSN, RN, Registered Nurse, Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Florence; G. Fiori, MD, Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Florence; F. Bartoli, MD, Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Florence; S. Guiducci, PhD, Researcher, Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Florence; S. Bellando Randone, PhD, Researcher, Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Florence; F. Galluccio, MD, Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Florence; L. Cometi, MD, Rheumatology Resident, Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Florence; S. Castellani, PhD, Associate Professor, Department of Clinical and Experimental Medicine, University of Florence; M. Boddi, PhD, Associate Professor, Department of Clinical and Experimental Medicine, University of Florence; A. Moggi Pignone, PhD, Associate Professor, Department of Internal Medicine, University of Florence; L. Rasero, BSN, RN, Associate Professor, Department of Clinical and Experimental Medicin

Bosentan blocks the antiangiogenic effects of sera from systemic sclerosis patients: an in vitro study.
Clin Exp Rheumatol 2015 Jul-Aug;33(4 Suppl 91):S148-52. Epub 2015 Jun 19.
Department of Experimental and Clinical Medicine, Section of Internal Medicine and Division of Rheumatology, Azienda Ospedaliero-Universitaria Careggi (AOUC), University of Florence, Florence, Italy.

Plexin-D1/Semaphorin 3E pathway may contribute to dysregulation of vascular tone control and defective angiogenesis in systemic sclerosis.
Arthritis Res Ther 2015 Aug 21;17:221. Epub 2015 Aug 21.
Department of Experimental and Clinical Medicine, Division of Rheumatology, Azienda Ospedaliero-Universitaria Careggi (AOUC), University of Florence, Viale Pieraccini 18, I-50139, Florence, Italy.

Evidence for oesophageal and anorectal involvement in very early systemic sclerosis (VEDOSS): report from a single VEDOSS/EUSTAR centre.
Ann Rheum Dis 2015 Jan 15;74(1):124-8. Epub 2013 Oct 15.
Department of Biomedicine, Division of Rheumatology AOUC and Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy.

Digital ulcers as a sentinel sign for early internal organ involvement in very early systemic sclerosis.
Rheumatology (Oxford) 2015 Jan 26;54(1):72-6. Epub 2014 Jul 26.
Department of Clinical and Experimental Medicine, Section of Rheumatology, University of Florence, Florence, Italy.


Disease activity improvement in rheumatoid arthritis treated with tumor necrosis factor-α inhibitors correlates with increased soluble Fas levels.
J Rheumatol 2014 Oct 1;41(10):1961-5. Epub 2014 Sep 1.
From the Department of Experimental and Clinical Medicine, Section of Internal Medicine; Division of Rheumatology, Azienda Ospedaliero-Universitaria Careggi; DENOthe Centre; Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy.E. Romano, PhD; R. Terenzi, MD; F. Peruzzi, MD; G. Fiori, MD; F. Nacci, MD; S. Bellando-Randone, MD, PhD; M. Matucci-Cerinic, MD, PhD; S. Guiducci, MD, PhD, Department of Experimental and Clinical Medicine, Section of Internal Medicine, Division of Rheumatology, Azienda Ospedaliero-Universitaria Careggi; DENOthe Centre; M. Manetti, PhD; Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence.


Lung ultrasound for the screening of interstitial lung disease in very early systemic sclerosis.
Ann Rheum Dis 2013 Mar 15;72(3):390-5. Epub 2012 May 15.
Department of Biomedicine, Division of Rheumatology, AOUC, Excellence Centre for Research, Transfer and High Education DENOthe, University of Florence, Via Pieraccini, 18-50139, Firenze, Italy.



Bone marrow-derived mesenchymal stem cells from early diffuse systemic sclerosis exhibit a paracrine machinery and stimulate angiogenesis in vitro.
Ann Rheum Dis 2011 Nov 6;70(11):2011-21. Epub 2011 Aug 6.
Department of Biomedicine, Division of Rheumatology, AOUC, Excellence Centre for Research, Transfer and High Education DENOthe, University of Florence, Florence, Italy.



Calcinosis in systemic sclerosis: subsets, distribution and complications.
Rheumatology (Oxford) 2016 09 30;55(9):1610-4. Epub 2016 May 30.
Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Florence, Italy.

Angiogenic T cell expansion correlates with severity of peripheral vascular damage in systemic sclerosis.
PLoS One 2017 10;12(8):e0183102. Epub 2017 Aug 10.
Department of Experimental and Clinical Medicine, Section of Internal Medicine, Azienda Ospedaliero-Universitaria Careggi (AOUC), University of Florence, Florence, Italy.

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