Publications by authors named "Silverio Perrotta"

100Publications

Juvenile erythrocytosis in children after liver transplantation: prevalence, risk factors and outcome.

Sci Rep 2020 Jun 16;10(1):9683. Epub 2020 Jun 16.

Pediatric Clinic, Department of Medicine, Surgery and Dentistry, University of Salerno, "Scuola Medica Salernitana", Baronissi (Salerno), Italy.

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http://dx.doi.org/10.1038/s41598-020-66586-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298026PMC
June 2020

A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent β-Thalassemia.

N Engl J Med 2020 03;382(13):1219-1231

From the Department of Clinical Sciences and Community, University of Milan, IRCCS Ca' Granda Foundation Maggiore Policlinico Hospital, Milan (M.D.C.), Centro della Microcitemia e Anemie Congenite e del Dismetabolismo del Ferro, E.O. Ospedali Galliera, Genoa (G.L.F.), Ospedale Pediatrico Microcitemico A. Cao, Azienda Ospedaliera G. Brotzu, Cagliari (R.O.), Ematologia e Oncologia Pediatrica, Università della Campania L. Vanvitelli, Caserta (S.P.), and the Department of Clinical and Biological Sciences, University of Turin, Turin (A.P.) - all in Italy; Siriraj Hospital, Mahidol University, Bangkok (V.V.), and the Division of Hematology, Department of Internal Medicine, Chiang Mai University, Chiang Mai (A. Tantiworawit) - both in Thailand; the Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon (A.T.T.); St. George University Hospital for Active Treatment and Medical University of Plovdiv, Plovdiv (P. Georgiev), University Specialized Hospital for Active Treatment in Oncology, Sofia (P. Ganeva), and University Hospital St. Marina, Varna (L.G.) - all in Bulgaria; the Division of Medical Oncology and Hematology, Department of Medicine, University Health Network and Division of Hematology, Department of Medicine, University of Toronto, Toronto (K.H.M.K.); the Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, and Keck School of Medicine of the University of Southern California, Los Angeles (T.C.), and the University of California San Francisco Benioff Children's Hospital, Oakland (A. Lal) - all in California; the Thalassemia and Sickle Cell Center, Laiko General Hospital (E. Voskaridou), and the First Department of Pediatrics, National and Kapodistrian University of Athens (A. Kattamis), Athens, and the Adult Thalassemia Unit, Hippokration Hospital, Thessaloniki (E. Vlachaki) - all in Greece; Hospital Sultanah Bahiyah, Alor Setar (H.K.L.), Hospital Umum, Sarawak, Kuching (L.P.C.), the University of Malaya Medical Center, Kuala Lumpur (P.C.B.), and Hospital Sultanah Aminah, Johor Bahru (S.M.L.) - all in Malaysia; the Comprehensive Center of Thalassemia, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel (I.P.-K.); Farhat Hached University Hospital, Sousse (A. Khelif), and the National Bone Marrow Transplant Center and Faculty of Medicine, University of Tunis El Manar, Tunis (M.B.) - both in Tunisia; the Department of Pediatric Hematology and Oncology, Ege University Hospital, Izmir, Turkey (Y.A.); Royal Prince Alfred Hospital and the University of Sydney, Sydney (P.J.H.); National Taiwan University, Taipei, Taiwan (M.-Y. L.); the Department of Haematology, Whittington Health NHS Trust (F.S.), and the Department of Haematology, University College London and University College London Hospitals NHS Foundation Trust (J.P.) - all in London; St. Jude Children's Research Hospital, Memphis, TN (E.J.N.); Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago (A. Thompson); Celgene, Summit, NJ (A. Laadem, J. Zou, J. Zhang); Celgene, Boudry, Switzerland (J.K.S., D.M., T.Z.); Acceleron Pharma, Cambridge, MA (P.G.L., M.L.S.); and the Department of Hematology, Necker Hospital, Assistance Publique-Hôpitaux de Paris (O.H.), and Imagine Institute, INSERM Unité 1163, University of Paris (O.H.) - both in Paris.

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http://dx.doi.org/10.1056/NEJMoa1910182DOI Listing
March 2020

Effects of Germline VHL Deficiency on Growth, Metabolism, and Mitochondria.

N Engl J Med 2020 02;382(9):835-844

From the Departments of Woman, Child, and General and Specialized Surgery (S.P., D.R., M. Caiazza, S.S., I.T., M. Casale), Precision Medicine (D.B., E.S., A.B., F.D.R.), and Advanced Medical and Surgical Sciences (A.A.S.), University of Campania Luigi Vanvitelli, Naples, and the Departments of Pharmacology and Biomolecular Science, University of Milan, Milan (P.C., A.M.R.) - both in Italy; the Departments of Physiology, Development, and Neuroscience (K.A.O., A.J.M.) and Biochemistry (J.A.W., J.L.G.), University of Cambridge, Cambridge, the Centre for Ultrastructural Imaging (L.A., R.A.F.) and the Centre for Human and Applied Physiological Sciences, Faculty of Life Sciences and Medicine (F.F.), King's College London, London, and the Department of Physiology, Anatomy, and Genetics (P.A.R., F.F.) and Nuffield Division of Anaesthetics (F.F.), University of Oxford, Oxford - all in the United Kingdom; and the Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia (C.F.-A.).

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http://dx.doi.org/10.1056/NEJMoa1907362DOI Listing
February 2020

Changing the diagnostic approach to diabetes insipidus: role of copeptin.

Ann Transl Med 2019 Dec;7(Suppl 8):S285

Department of Pediatrics, IRCCS Istituto Giannina Gaslini, University of Genova, Genova, Italy.

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http://dx.doi.org/10.21037/atm.2019.11.80DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976509PMC
December 2019

Asymptomatic intracranial aneurysms in beta-thalassemia: a three-year follow-up report.

Orphanet J Rare Dis 2020 01 20;15(1):21. Epub 2020 Jan 20.

Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Università degli studi della Campania "Luigi Vanvitelli", Via L. De Crecchio 4, Naples, Italy.

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http://dx.doi.org/10.1186/s13023-020-1302-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971974PMC
January 2020

Brain iron content in systemic iron overload: A beta-thalassemia quantitative MRI study.

Neuroimage Clin 2019 25;24:102058. Epub 2019 Oct 25.

Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Baronissi, Salerno 84081, Italy; Department of Diagnostic Imaging, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Scuola Medica Salernitana, Salerno 84131, Italy.

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http://dx.doi.org/10.1016/j.nicl.2019.102058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849415PMC
October 2019

Hb Vanvitelli: A new unstable α-globin chain variant causes undiagnosed chronic haemolytic anaemia when co-inherited with deletion - α.

Clin Biochem 2019 Dec 4;74:80-85. Epub 2019 Sep 4.

Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00099120193085
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http://dx.doi.org/10.1016/j.clinbiochem.2019.09.002DOI Listing
December 2019

No increased cerebrovascular involvement in adult beta-thalassemia by advanced MRI analyses.

Blood Cells Mol Dis 2019 09 2;78:9-13. Epub 2019 May 2.

Dipartimento di Medicina e Chirurgia, Scuola Medica Salernitana, Sezione di Neuroscienze, Università di Salerno, Salerno, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2019.05.001DOI Listing
September 2019

The Endocannabinoid/Endovanilloid System in Bone: From Osteoporosis to Osteosarcoma.

Int J Mol Sci 2019 Apr 18;20(8). Epub 2019 Apr 18.

Department of Women, Child, and General and Specialized Surgery, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.

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https://www.mdpi.com/1422-0067/20/8/1919
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http://dx.doi.org/10.3390/ijms20081919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514542PMC
April 2019

Nineteen-month-old girl with persistent fever.

Arch Dis Child Educ Pract Ed 2019 Feb 23. Epub 2019 Feb 23.

Pediatric Hematology Unit, Department of Woman, Child and of General and Specialized Surgery, Università degli Studi della Campania, Naples, Italy.

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http://dx.doi.org/10.1136/archdischild-2018-316493DOI Listing
February 2019

Report on a child with neurofibromatosis type 2 and unilateral moyamoya: further evidence of cerebral vasculopathy in NF2.

Neurol Sci 2019 07 21;40(7):1475-1476. Epub 2019 Jan 21.

Referral Centre of Neurofibromatosis, Department of Woman and Child, Specialistic and General Surgery, Università degli Studi della Campania "Luigi Vanvitelli", Via L. De Crecchio 4, 80138, Naples, Italy.

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http://dx.doi.org/10.1007/s10072-019-3728-8DOI Listing
July 2019

Iron chelating properties of Eltrombopag: Investigating its role in thalassemia-induced osteoporosis.

PLoS One 2018 3;13(12):e0208102. Epub 2018 Dec 3.

Department of Woman, Child and General and Special Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208102PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277068PMC
May 2019

Life-Threatening Drug-Induced Liver Injury in a Patient with β-Thalassemia Major and Severe Iron Overload on Polypharmacy.

Hemoglobin 2018 May 25;42(3):213-216. Epub 2018 Sep 25.

a Department of Women, Child and General and Specialized Surgery , University of Campania 'Luigi Vanvitelli' , Naples , Italy.

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http://dx.doi.org/10.1080/03630269.2018.1503187DOI Listing
May 2018

Childhood Head and Neck Lymphadenopathy: A Report by a Single Institution (2003-2017).

J Pediatr Hematol Oncol 2019 01;41(1):17-20

Unit of Hematology-Oncology, Pediatric Department of University "L. Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1097/MPH.0000000000001273DOI Listing
January 2019

Risk factors for heart disease in transfusion-dependent thalassemia: serum ferritin revisited.

Intern Emerg Med 2019 04 12;14(3):365-370. Epub 2018 Jun 12.

Ematologia-Centro della Microcitemia e Anemie Congenite, Ospedale Galliera, Via Volta 6, 16128, Genoa, Italy.

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http://dx.doi.org/10.1007/s11739-018-1890-2DOI Listing
April 2019

A 23-month-old girl with chronic 'seborrhoeic' dermatitis, dehydration and failure to thrive.

Arch Dis Child Educ Pract Ed 2019 06 27;104(3):154-156. Epub 2018 Apr 27.

Department of Woman, Child and General and Specialized Surgery, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Campania, Italy.

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http://dx.doi.org/10.1136/archdischild-2018-314828DOI Listing
June 2019

Seizures in children with neurofibromatosis type 1: is neurofibromatosis type 1 enough?

Ital J Pediatr 2018 Mar 22;44(1):41. Epub 2018 Mar 22.

Centro di Riferimento Pediatrico delle Neurofibromatosi, Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Università degli Studi della Campania "L. Vanvitelli", Caserta, Italy.

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http://dx.doi.org/10.1186/s13052-018-0477-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863905PMC
March 2018

Medullary unidentified bright objects in Neurofibromatosis type 1: a case series.

BMC Pediatr 2018 02 28;18(1):91. Epub 2018 Feb 28.

Department of Advanced Biomedical Sciences, "Federico II" University, via Sergio Pansini 5, 80100, Naples, Italy.

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http://dx.doi.org/10.1186/s12887-018-1067-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832195PMC
February 2018

Hereditary hypochromic microcytic anemia associated with loss-of-function DMT1 gene mutations and absence of liver iron overload.

Am J Hematol 2018 03 8;93(3):E58-E60. Epub 2017 Dec 8.

Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Università della Campania "L. Vanvitelli", Italy.

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http://dx.doi.org/10.1002/ajh.24988DOI Listing
March 2018

From Gardner fibroma diagnosis to constitutional mutation detection: a one-way street.

Clin Case Rep 2017 10 10;5(10):1557-1560. Epub 2017 Aug 10.

Dipartimento della Donnadel Bambino e della Chirurgia generale e specialistica Università degli Studi della Campania Luigi Vanvitelli Naples Italy.

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http://dx.doi.org/10.1002/ccr3.1065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628198PMC
October 2017

Moyamoya syndrome in children with neurofibromatosis type 1: Italian-French experience.

Am J Med Genet A 2017 Jun 19;173(6):1521-1530. Epub 2017 Apr 19.

Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Università degli Studi della Campania "Luigi Vanvitelli,", Naples, Italy.

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http://dx.doi.org/10.1002/ajmg.a.38212DOI Listing
June 2017

Time trends of cancer incidence in childhood in Campania region: 25 years of observation.

Ital J Pediatr 2016 Sep 6;42(1):82. Epub 2016 Sep 6.

Servizio di Oncologia Pediatrica, Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica- Seconda Università degli Studi di Napoli, Naples, Italy.

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http://dx.doi.org/10.1186/s13052-016-0287-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013613PMC
September 2016

Very early onset of autoimmune thyroiditis in a toddler with severe hypothyroidism presentation: a case report.

Ital J Pediatr 2016 Jun 18;42(1):61. Epub 2016 Jun 18.

Department of Woman, Child and General and Specialized Surgery, Seconda Università degli Studi di Napoli, Via L. De Crecchio n° 2, 80138, Naples, Italy.

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http://dx.doi.org/10.1186/s13052-016-0270-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912771PMC
June 2016

Unusual association of non-anaplastic Wilms tumor and Cornelia de Lange syndrome: case report.

BMC Cancer 2016 06 13;16:365. Epub 2016 Jun 13.

Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Seconda Università degli Studi di Napoli, Via Luigi De Crecchio 4, Naples, 80138, Italy.

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http://dx.doi.org/10.1186/s12885-016-2402-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904356PMC
June 2016

Iron overload enhances human mesenchymal stromal cell growth and hampers matrix calcification.

Biochim Biophys Acta 2016 Jun 3;1860(6):1211-23. Epub 2016 Feb 3.

Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, 80138 Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2016.01.025DOI Listing
June 2016

Serum Hepcidin and Iron Absorption in Paediatric Inflammatory Bowel Disease.

J Crohns Colitis 2016 May 4;10(5):566-74. Epub 2016 Jan 4.

Department of Translational Medical Science, Section of Paediatrics, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1093/ecco-jcc/jjv242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957448PMC
May 2016

Arg(1809) substitution in neurofibromin: further evidence of a genotype-phenotype correlation in neurofibromatosis type 1.

Eur J Hum Genet 2015 Nov 13;23(11):1460-1. Epub 2015 May 13.

Dipartimento di Biochimica Biofisica e Patologia Generale, Seconda Università degli Studi di Napoli, Napoli, Italy.

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http://dx.doi.org/10.1038/ejhg.2015.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613473PMC
November 2015

Early-onset central diabetes insipidus is associated with de novo arginine vasopressin-neurophysin II or Wolfram syndrome 1 gene mutations.

Eur J Endocrinol 2015 Apr;172(4):461-72

Dipartimento della Donnadel Bambino e di Chirurgia Generale e Specialistica, Second University of Naples, via De Crecchio 4, Naples, ItalyIstituto Giannina GasliniUniversity of Genova, 16147 Genova, ItalyDepartment of BiochemistryBiophysics, and General Pathology, Second University of Naples, via De Crecchio 7, Naples, ItalyIstituto Giannina GasliniLargo Gerolamo Gaslini 5, 16147 Genova, ItalyUnit of Endocrinology and DiabetologyBambino Gesù Children's Hospital, IRCCS, Rome, ItalyPediatric Endocrinology UnitDepartment of Translational Medical Sciences, University 'Federico II' of Naples, Naples, ItalyDivision of Internal MedicineSecond University of Naples, 80100 Naples, Italy

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https://eje.bioscientifica.com/view/journals/eje/172/4/461.x
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http://dx.doi.org/10.1530/EJE-14-0942DOI Listing
April 2015

Erythrocyte genotyping for transfusion-dependent patients at the Azienda Universitaria Policlinico of Naples.

Transfus Apher Sci 2015 Feb 18;52(1):72-7. Epub 2014 Dec 18.

U.O.C. Immunohematology, Transfusion Medicine and Transplant Immunology (SIMT), Regional Reference Laboratory of Transplant Immunology (LIT), Azienda Universitaria Policlinico (AOU), Second University of Naples (SUN), Italy; Department of Biochemistry, Biophysics and General Pathology, Second University of Naples (SUN), Italy.

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http://dx.doi.org/10.1016/j.transci.2014.12.006DOI Listing
February 2015

Resveratrol mimics insulin activity in the adipogenic commitment of human bone marrow mesenchymal stromal cells.

Int J Biochem Cell Biol 2015 Mar 3;60:60-72. Epub 2015 Jan 3.

Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2014.12.011DOI Listing
March 2015

Endocrine function and bone disease during long-term chelation therapy with deferasirox in patients with β-thalassemia major.

Am J Hematol 2014 Dec 26;89(12):1102-6. Epub 2014 Sep 26.

Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Second University of Naples, Naples, Italy.

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http://dx.doi.org/10.1002/ajh.23844DOI Listing
December 2014

Determination of deferasirox plasma concentrations: do gender, physical and genetic differences affect chelation efficacy?

Eur J Haematol 2015 Apr 17;94(4):310-7. Epub 2014 Sep 17.

Department of Internal Medicine, Clinical Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.

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http://doi.wiley.com/10.1111/ejh.12419
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http://dx.doi.org/10.1111/ejh.12419DOI Listing
April 2015

Cardiac autonomic regulation in response to a mixed meal is impaired in obese children and adolescents: the role played by insulin resistance.

J Clin Endocrinol Metab 2014 Sep 19;99(9):3199-207. Epub 2014 May 19.

Division of Internal Medicine (D.C., G.P.), Division of Endocrinology (K.E., A.D.B.), and Department of Pediatrics (S.P., L.P., E.M.d.G.), Second University of Naples, 80131 Naples, Italy; Department of Internal Medicine (R.F.), Humanitas Clinical and Research Center, Rozzano, BIOMETRA Department, University of Milan, 20122 Milan, Italy; and Division of Cardiology (D.T.), University of Catanzaro, 88100 Catanzaro, Italy.

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http://dx.doi.org/10.1210/jc.2013-4211DOI Listing
September 2014

LEOPARD syndrome: clinical dilemmas in differential diagnosis of RASopathies.

BMC Med Genet 2014 Apr 26;15:44. Epub 2014 Apr 26.

Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Second University of Naples, Via Luigi De Crecchio, 4, Naples 80138, Italy.

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http://bmcmedgenet.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2350-15-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005403PMC
April 2014

Prevalence and risk factors for pulmonary arterial hypertension in a large group of β-thalassemia patients using right heart catheterization: a Webthal study.

Circulation 2014 Jan 30;129(3):338-45. Epub 2013 Sep 30.

Galliera Hospital, Genoa, Italy (G.D., V.P., G.L.F.); University of Cagliari, Cagliari, Italy (R.G., P.B., M.-E.L.); IRCCS Ca' Granda Foundation Maggiore Policlinico Hospital, University of Milan, Milan, Italy (M.D.C., K.M.M.); University of Turin, Turin, Italy (A.P.); Perrino Hospital, Brindisi, Italy (A.Q.); S. Francesco Hospital, Nuoro, Italy (G.C.); and Seconda University, Naples, Italy (S.P.).

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http://circ.ahajournals.org/content/early/2013/09/30/CIRCULA
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http://circ.ahajournals.org/cgi/doi/10.1161/CIRCULATIONAHA.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.002124DOI Listing
January 2014

Splenectomy for hereditary spherocytosis: complete, partial or not at all?

Expert Rev Hematol 2011 Dec;4(6):627-35

Department of Pediatrics, Second University of Naples, Naples, Italy.

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http://www.tandfonline.com/doi/full/10.1586/ehm.11.51
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http://dx.doi.org/10.1586/ehm.11.51DOI Listing
December 2011

p57(Kip2) and cancer: time for a critical appraisal.

Mol Cancer Res 2011 Oct 4;9(10):1269-84. Epub 2011 Aug 4.

Department of Biochemistry and Biophysics, Second University of Naples, Naples, Italy.

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http://dx.doi.org/10.1158/1541-7786.MCR-11-0220DOI Listing
October 2011

Reliability of EMA binding test in the diagnosis of hereditary spherocytosis in Italian patients.

Acta Haematol 2011 11;125(3):136-40. Epub 2010 Dec 11.

Azienda Ospedali Riuniti Villa Sofia - Cervello, Ospedale V. Cervello, U.O.C. Ematologia II, Laboratorio di Ricerca 'Piera Cutino', Palermo, Italia.

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http://dx.doi.org/10.1159/000322253DOI Listing
May 2011

p57Kip2 is a downstream effector of BCR-ABL kinase inhibitors in chronic myelogenous leukemia cells.

Carcinogenesis 2011 Jan 15;32(1):10-8. Epub 2010 Oct 15.

Department of Biochemistry and Biophysics "Francesco Cedrangolo", Second University of Naples, Italy.

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http://dx.doi.org/10.1093/carcin/bgq211DOI Listing
January 2011