Silke Szymczak

Silke Szymczak

UNVERIFIED PROFILE

Are you Silke Szymczak?   Register this Author

Register author
Silke Szymczak

Silke Szymczak

Publications by authors named "Silke Szymczak"

Are you Silke Szymczak?   Register this Author

54Publications

1576Reads

47Profile Views

Heterogeneous intracellular TRAIL-receptor distribution predicts poor outcome in breast cancer patients.

J Mol Med (Berl) 2019 Aug 10;97(8):1155-1167. Epub 2019 Jun 10.

Institute for Experimental Cancer Research, Christian-Albrechts-University of Kiel, Arnold-Heller Str. 3 (Haus 17), 24105, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-019-01805-wDOI Listing
August 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698888PMC
June 2019

Evaluation of variable selection methods for random forests and omics data sets.

Brief Bioinform 2019 03;20(2):492-503

Institute of Medical Informatics and Statistics, Kiel University, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bib/bbx124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433899PMC
March 2019

Surrogate minimal depth as an importance measure for variables in random forests.

Bioinformatics 2019 Mar 1. Epub 2019 Mar 1.

Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, Brunswiker Str. 10, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btz149DOI Listing
March 2019

Histologic improvement of NAFLD in patients with obesity after bariatric surgery based on standardized NAS (NAFLD activity score).

Surg Obes Relat Dis 2018 Oct 24;14(10):1607-1616. Epub 2018 Jul 24.

Department of General, Visceral, Thoracic, Transplantation and Pediatric Surgery, University Hospital Schleswig-Holstein, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.soard.2018.07.012DOI Listing
October 2018

NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia.

Epigenomics 2018 02 15;10(2):133-147. Epub 2018 Jan 15.

Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel 24105, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi-2017-0080DOI Listing
February 2018

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases.

Gastroenterology 2017 12 19;153(6):1504-1516.e2. Epub 2017 Aug 19.

Department of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany; Institute of Clinical Molecular Biology, University of Kiel, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2017.08.028DOI Listing
December 2017

Topography of essential tremor.

Parkinsonism Relat Disord 2017 Jul 20;40:58-63. Epub 2017 Apr 20.

Department of Neurology, University Hospital Schleswig Holstein, 24105 Kiel, Germany; Department of Neurology, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 200011 Shanghai, China. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S13538020173014
Publisher Site
http://dx.doi.org/10.1016/j.parkreldis.2017.04.012DOI Listing
July 2017

Serologic Anti-GP2 Antibodies Are Associated with Genetic Polymorphisms, Fibrostenosis, and Need for Surgical Resection in Crohn's Disease.

Inflamm Bowel Dis 2016 11;22(11):2648-2657

*Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany; †Department of Internal Medicine I, University Medical Center Regensburg, Regensburg, Germany; ‡Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio; §Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland; ‖Faculty of Science, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany; ¶Institute of Molecular and Clinical Immunology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany; **Institute of Medical Informatics and Statistics, Christian-Albrechts-University of Kiel, Kiel, Germany; ††Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland; and ‡‡Department of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic Foundation, Cleveland, Ohio.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082182PMC
http://dx.doi.org/10.1097/MIB.0000000000000936DOI Listing
November 2016

Comparison of parametric and machine methods for variable selection in simulated Genetic Analysis Workshop 19 data.

BMC Proc 2016 18;10(Suppl 7):147-152. Epub 2016 Oct 18.

Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive, Suite 1200, Baltimore, MD 21224 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12919-016-0021-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133476PMC
October 2016

Genome-wide association study of serum coenzyme Q10 levels identifies susceptibility loci linked to neuronal diseases.

Hum Mol Genet 2016 07 5;25(13):2881-2891. Epub 2016 May 5.

Division of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian-Albrechts-University of Kiel, Heinrich-Hecht-Platz 10, 24118 Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddw134DOI Listing
July 2016

Variable selection method for the identification of epistatic models.

Pac Symp Biocomput 2015 :195-206

Computational and Statistical Genomics Branch (NHGRI, NIH), Baltimore, MD 21224, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299919PMC
April 2016

r2VIM: A new variable selection method for random forests in genome-wide association studies.

BioData Min 2016 1;9. Epub 2016 Feb 1.

Statistical Genetics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, 333 Cassell Dr, 21224 Baltimore, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13040-016-0087-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736152PMC
February 2016

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

Authors:
Norihiro Kato Marie Loh Fumihiko Takeuchi Niek Verweij Xu Wang Weihua Zhang Tanika N Kelly Danish Saleheen Benjamin Lehne Irene Mateo Leach Alexander W Drong James Abbott Simone Wahl Sian-Tsung Tan William R Scott Gianluca Campanella Marc Chadeau-Hyam Uzma Afzal Tarunveer S Ahluwalia Marc Jan Bonder Peng Chen Abbas Dehghan Todd L Edwards Tõnu Esko Min Jin Go Sarah E Harris Jaana Hartiala Silva Kasela Anuradhani Kasturiratne Chiea-Chuen Khor Marcus E Kleber Huaixing Li Zuan Yu Mok Masahiro Nakatochi Nur Sabrina Sapari Richa Saxena Alexandre F R Stewart Lisette Stolk Yasuharu Tabara Ai Ling Teh Ying Wu Jer-Yuarn Wu Yi Zhang Imke Aits Alexessander Da Silva Couto Alves Shikta Das Rajkumar Dorajoo Jemma C Hopewell Yun Kyoung Kim Robert W Koivula Jian'an Luan Leo-Pekka Lyytikäinen Quang N Nguyen Mark A Pereira Iris Postmus Olli T Raitakari Molly Scannell Bryan Robert A Scott Rossella Sorice Vinicius Tragante Michela Traglia Jon White Ken Yamamoto Yonghong Zhang Linda S Adair Alauddin Ahmed Koichi Akiyama Rasheed Asif Tin Aung Inês Barroso Andrew Bjonnes Timothy R Braun Hui Cai Li-Ching Chang Chien-Hsiun Chen Ching-Yu Cheng Yap-Seng Chong Rory Collins Regina Courtney Gail Davies Graciela Delgado Loi D Do Pieter A Doevendans Ron T Gansevoort Yu-Tang Gao Tanja B Grammer Niels Grarup Jagvir Grewal Dongfeng Gu Gurpreet S Wander Anna-Liisa Hartikainen Stanley L Hazen Jing He Chew-Kiat Heng James E Hixson Albert Hofman Chris Hsu Wei Huang Lise L N Husemoen Joo-Yeon Hwang Sahoko Ichihara Michiya Igase Masato Isono Johanne M Justesen Tomohiro Katsuya Muhammad G Kibriya Young Jin Kim Miyako Kishimoto Woon-Puay Koh Katsuhiko Kohara Meena Kumari Kenneth Kwek Nanette R Lee Jeannette Lee Jiemin Liao Wolfgang Lieb David C M Liewald Tatsuaki Matsubara Yumi Matsushita Thomas Meitinger Evelin Mihailov Lili Milani Rebecca Mills Nina Mononen Martina Müller-Nurasyid Toru Nabika Eitaro Nakashima Hong Kiat Ng Kjell Nikus Teresa Nutile Takayoshi Ohkubo Keizo Ohnaka Sarah Parish Lavinia Paternoster Hao Peng Annette Peters Son T Pham Mohitha J Pinidiyapathirage Mahfuzar Rahman Hiromi Rakugi Olov Rolandsson Michelle Ann Rozario Daniela Ruggiero Cinzia F Sala Ralhan Sarju Kazuro Shimokawa Harold Snieder Thomas Sparsø Wilko Spiering John M Starr David J Stott Daniel O Stram Takao Sugiyama Silke Szymczak W H Wilson Tang Lin Tong Stella Trompet Väinö Turjanmaa Hirotsugu Ueshima André G Uitterlinden Satoshi Umemura Marja Vaarasmaki Rob M van Dam Wiek H van Gilst Dirk J van Veldhuisen Jorma S Viikari Melanie Waldenberger Yiqin Wang Aili Wang Rory Wilson Tien-Yin Wong Yong-Bing Xiang Shuhei Yamaguchi Xingwang Ye Robin D Young Terri L Young Jian-Min Yuan Xueya Zhou Folkert W Asselbergs Marina Ciullo Robert Clarke Panos Deloukas Andre Franke Paul W Franks Steve Franks Yechiel Friedlander Myron D Gross Zhirong Guo Torben Hansen Marjo-Riitta Jarvelin Torben Jørgensen J Wouter Jukema Mika Kähönen Hiroshi Kajio Mika Kivimaki Jong-Young Lee Terho Lehtimäki Allan Linneberg Tetsuro Miki Oluf Pedersen Nilesh J Samani Thorkild I A Sørensen Ryoichi Takayanagi Daniela Toniolo Habibul Ahsan Hooman Allayee Yuan-Tsong Chen John Danesh Ian J Deary Oscar H Franco Lude Franke Bastiaan T Heijman Joanna D Holbrook Aaron Isaacs Bong-Jo Kim Xu Lin Jianjun Liu Winfried März Andres Metspalu Karen L Mohlke Dharambir K Sanghera Xiao-Ou Shu Joyce B J van Meurs Eranga Vithana Ananda R Wickremasinghe Cisca Wijmenga Bruce H W Wolffenbuttel Mitsuhiro Yokota Wei Zheng Dingliang Zhu Paolo Vineis Soterios A Kyrtopoulos Jos C S Kleinjans Mark I McCarthy Richie Soong Christian Gieger James Scott Yik-Ying Teo Jiang He Paul Elliott E Shyong Tai Pim van der Harst Jaspal S Kooner John C Chambers

Nat Genet 2015 11 21;47(11):1282-1293. Epub 2015 Sep 21.

Department of Epidemiology and Biostatistics, Imperial College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719169PMC
November 2015

Vy-PER: eliminating false positive detection of virus integration events in next generation sequencing data.

Sci Rep 2015 Jul 13;5:11534. Epub 2015 Jul 13.

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Schleswig-Holstein, D-24105 Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep11534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499804PMC
July 2015

Chromosomal aneuploidy affects the global proteome equilibrium of colorectal cancer cells.

Anal Cell Pathol (Amst) 2013 ;36(5-6):149-61

Section for Translational Surgical Oncology & Biobanking, Department of Surgery, University of Lübeck, Lübeck, Germany Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/ACP-140088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605604PMC
February 2015

Association between SNPs in defined functional pathways and risk of early or late toxicity as well as individual radiosensitivity.

Strahlenther Onkol 2015 Jan 26;191(1):59-66. Epub 2014 Aug 26.

Laboratory of Radiobiology & Experimental Radiooncology, Department of Radiotherapy and Radiooncology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/s00066-014-0741
Web Search
http://link.springer.com/10.1007/s00066-014-0741-y
Publisher Site
http://dx.doi.org/10.1007/s00066-014-0741-yDOI Listing
January 2015

False-positive rates in two-point parametric linkage analysis.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S110. Epub 2014 Jun 17.

Statistical Genetics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive, Suite 1200, Baltimore, MD 21224, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1753-6561-8-S1-S110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143621PMC
December 2014

Risk estimation using probability machines.

BioData Min 2014 Mar 1;7(1). Epub 2014 Mar 1.

Clinical Trials and Outcomes Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Room 4-1350, Bldg 10 CRC, 10 Center Drive, Bethesda, MD 20892-1468, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1756-0381-7-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015350PMC
March 2014

Adaptive linear rank tests for eQTL studies.

Stat Med 2013 Feb 30;32(3):524-37. Epub 2012 Aug 30.

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Maria-Goeppert-Str. 1, 23562 Lübeck, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.5593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739449PMC
February 2013

Deregulation of a distinct set of microRNAs is associated with transformation of gastritis into MALT lymphoma.

Virchows Arch 2012 Apr 7;460(4):371-7. Epub 2012 Mar 7.

Institut für Pathologie und Referenzzentrum für Hämatopathologie und Lymphknotendiagnostik, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Universität zu Lübeck, Lübeck, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-012-1215-1DOI Listing
April 2012

Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy.

Radiat Oncol 2012 Apr 26;7:65. Epub 2012 Apr 26.

Department of Radiotherapy and Radiooncology, Laboratory of Radiobiology & Experimental Radiooncology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistr 52, D-20246 Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1748-717X-7-65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439287PMC
April 2012

Protein profiling of genomic instability in endometrial cancer.

Cell Mol Life Sci 2012 Jan 8;69(2):325-33. Epub 2011 Jul 8.

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00018-011-0752-0DOI Listing
January 2012

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.

Circ Cardiovasc Genet 2011 Aug 23;4(4):403-12. Epub 2011 May 23.

Department of Medicine II, University Medical Center Mainz, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGENETICS.110.958728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157552PMC
August 2011

Association of single nucleotide polymorphisms in ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with clinical and cellular radiosensitivity.

Radiother Oncol 2010 Oct 17;97(1):26-32. Epub 2010 Feb 17.

Hubertus Wald Tumorzentrum, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radonc.2010.01.016DOI Listing
October 2010

The potential role of G2- but not of G0-radiosensitivity for predisposition of prostate cancer.

Radiother Oncol 2010 Jul 7;96(1):19-24. Epub 2010 May 7.

Laboratory of Radiobiology & Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radonc.2010.04.018DOI Listing
July 2010

Machine learning in genome-wide association studies.

Genet Epidemiol 2009 ;33 Suppl 1:S51-7

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gepi.20473DOI Listing
March 2010

Stress sensitivity is increased in transgenic rats with low brain angiotensinogen.

J Endocrinol 2010 Jan 6;204(1):85-92. Epub 2009 Oct 6.

Institute of Experimental and Clinical Pharmacology and Toxicology Institute of Medical Biometry and Statistics, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1677/JOE-09-0363DOI Listing
January 2010

Picking single-nucleotide polymorphisms in forests.

BMC Proc 2007 18;1 Suppl 1:S59. Epub 2007 Dec 18.

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367487PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s59DOI Listing
December 2009

Genetic association studies for gene expressions: permutation-based mutual information in a comparison with standard ANOVA and as a novel approach for feature selection.

BMC Proc 2007 18;1 Suppl 1:S9. Epub 2007 Dec 18.

Institute of Medical Biometry and Statistics, University Hospital Schleswig-Holstein, Campus Lübeck, University at Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359872PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s9DOI Listing
December 2009

ACPA: automated cluster plot analysis of genotype data.

BMC Proc 2009 Dec 15;3 Suppl 7:S58. Epub 2009 Dec 15.

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, 23538 Lübeck, Germany.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795958PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s58DOI Listing
December 2009

Evaluation of single-nucleotide polymorphism imputation using random forests.

BMC Proc 2009 Dec 15;3 Suppl 7:S65. Epub 2009 Dec 15.

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Scleswig-Holstein, Campus Lübeck, Maria-Goeppert-Str, 1, 23562 Lübeck, Germany.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795966PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s65DOI Listing
December 2009

Individual radiosensitivity measured with lymphocytes may predict the risk of acute reaction after radiotherapy.

Int J Radiat Oncol Biol Phys 2008 May;71(1):256-64

Clinic for Radiotherapy and Radiation Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2008.01.007DOI Listing
May 2008

Genome-wide association analyses of expression phenotypes.

Genet Epidemiol 2007 ;31 Suppl 1:S7-S11

Department of Epidemiology and Biostatistics, Institute for Human Genetics, University of California at San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gepi.20275DOI Listing
April 2008

Identification of genes relevant to symbiosis and competitiveness in Sinorhizobium meliloti using signature-tagged mutants.

Mol Plant Microbe Interact 2008 Feb;21(2):219-31

Institute for Genome Research and Systems Biology, Center for Biotechnology, Bielefeld University, 33594 Bielefeld, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1094/MPMI-21-2-0219DOI Listing
February 2008