Publications by authors named "Sigurgeir Olafsson"

11Publications

Somatic Evolution in Non-neoplastic IBD-Affected Colon.

Authors:
Sigurgeir Olafsson Rebecca E McIntyre Tim Coorens Timothy Butler Hyunchul Jung Philip S Robinson Henry Lee-Six Mathijs A Sanders Kenneth Arestang Claire Dawson Monika Tripathi Konstantina Strongili Yvette Hooks Michael R Stratton Miles Parkes Inigo Martincorena Tim Raine Peter J Campbell Carl A Anderson

Cell 2020 Aug 21;182(3):672-684.e11. Epub 2020 Jul 21.

Wellcome Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK. Electronic address:

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August 2020

Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood.

Authors:
Sigurgeir Olafsson Kristjan F Alexandersson Johann G K Gizurarson Katrin Hauksdottir Orvar Gunnarsson Karl Olafsson Julius Gudmundsson Simon N Stacey Gardar Sveinbjornsson Jona Saemundsdottir Einar S Bjornsson Sigurdur Olafsson Sigurdur Bjornsson Kjartan B Orvar Arnor Vikingsson Arni J Geirsson Sturla Arinbjarnarson Gyda Bjornsdottir Thorgeir E Thorgeirsson Snaevar Sigurdsson Gisli H Halldorsson Olafur T Magnusson Gisli Masson Hilma Holm Ingileif Jonsdottir Olof Sigurdardottir Gudmundur I Eyjolfsson Isleifur Olafsson Patrick Sulem Unnur Thorsteinsdottir Thorvaldur Jonsson Thorunn Rafnar Daniel F Gudbjartsson Kari Stefansson

Cancer Epidemiol Biomarkers Prev 2020 01 30;29(1):225-235. Epub 2019 Oct 30.

deCODE genetics/AMGEN, Reykjavik, Iceland.

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January 2020

The landscape of somatic mutation in normal colorectal epithelial cells.

Authors:
Henry Lee-Six Sigurgeir Olafsson Peter Ellis Robert J Osborne Mathijs A Sanders Luiza Moore Nikitas Georgakopoulos Franco Torrente Ayesha Noorani Martin Goddard Philip Robinson Tim H H Coorens Laura O'Neill Christopher Alder Jingwei Wang Rebecca C Fitzgerald Matthias Zilbauer Nicholas Coleman Kourosh Saeb-Parsy Inigo Martincorena Peter J Campbell Michael R Stratton

Nature 2019 10 23;574(7779):532-537. Epub 2019 Oct 23.

Wellcome Sanger Institute, Hinxton, UK.

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October 2019

Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk.

Authors:
Katarina Tengvall Jesse Huang Cecilia Hellström Patrick Kammer Martin Biström Burcu Ayoglu Izaura Lima Bomfim Pernilla Stridh Julia Butt Nicole Brenner Angelika Michel Karin Lundberg Leonid Padyukov Ingrid E Lundberg Elisabet Svenungsson Ingemar Ernberg Sigurgeir Olafsson Alexander T Dilthey Jan Hillert Lars Alfredsson Peter Sundström Peter Nilsson Tim Waterboer Tomas Olsson Ingrid Kockum

Proc Natl Acad Sci U S A 2019 08 2;116(34):16955-16960. Epub 2019 Aug 2.

Neuroimmunology Unit, The Karolinska Neuroimmunology & Multiple Sclerosis Centre, Department of Clinical Neuroscience, Karolinska Institute, 171 76 Stockholm, Sweden.

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August 2019

DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis.

Authors:
Lara Kular Yun Liu Sabrina Ruhrmann Galina Zheleznyakova Francesco Marabita David Gomez-Cabrero Tojo James Ewoud Ewing Magdalena Lindén Bartosz Górnikiewicz Shahin Aeinehband Pernilla Stridh Jenny Link Till F M Andlauer Christiane Gasperi Heinz Wiendl Frauke Zipp Ralf Gold Björn Tackenberg Frank Weber Bernhard Hemmer Konstantin Strauch Stefanie Heilmann-Heimbach Rajesh Rawal Ulf Schminke Carsten O Schmidt Tim Kacprowski Andre Franke Matthias Laudes Alexander T Dilthey Elisabeth G Celius Helle B Søndergaard Jesper Tegnér Hanne F Harbo Annette B Oturai Sigurgeir Olafsson Hannes P Eggertsson Bjarni V Halldorsson Haukur Hjaltason Elias Olafsson Ingileif Jonsdottir Kari Stefansson Tomas Olsson Fredrik Piehl Tomas J Ekström Ingrid Kockum Andrew P Feinberg Maja Jagodic

Nat Commun 2018 06 19;9(1):2397. Epub 2018 Jun 19.

Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.

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June 2018

Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations.

Authors:
Sigurgeir Olafsson Pernilla Stridh Steffan Daniël Bos Andres Ingason Jack Euesden Patrick Sulem Gudmar Thorleifsson Omar Gustafsson Ari Johannesson Arni J Geirsson Arni V Thorsson Bardur Sigurgeirsson Bjorn Runar Ludviksson Elias Olafsson Helga Kristjansdottir Jon G Jonasson Jon Hjaltalin Olafsson Kjartan B Orvar Rafn Benediktsson Ragnar Bjarnason Sjofn Kristjansdottir Thorarinn Gislason Trausti Valdimarsson Evgenia Mikaelsdottir Snaevar Sigurdsson Stefan Jonsson Thorunn Rafnar Dag Aarsland Srdjan Djurovic Tormod Fladby Gun Peggy Knudsen Elisabeth G Celius Kjell-Morten Myhr Gerdur Grondal Kristjan Steinsson Helgi Valdimarsson Sigurdur Bjornsson Unnur S Bjornsdottir Einar S Bjornsson Bjorn Nilsson Ole A Andreassen Lars Alfredsson Jan Hillert Ingrid Skelton Kockum Gisli Masson Unnur Thorsteinsdottir Daniel F Gudbjartsson Hreinn Stefansson Haukur Hjaltason Hanne F Harbo Tomas Olsson Ingileif Jonsdottir Kari Stefansson

NPJ Genom Med 2017 8;2:24. Epub 2017 Aug 8.

deCODE genetics/Amgen, Reykjavik, Iceland.

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August 2017

Identification of sequence variants influencing immunoglobulin levels.

Authors:
Stefan Jonsson Gardar Sveinbjornsson Aitzkoa Lopez de Lapuente Portilla Bhairavi Swaminathan Rosina Plomp Gillian Dekkers Ram Ajore Mina Ali Arthur E H Bentlage Evelina Elmér Gudmundur I Eyjolfsson Sigurjon A Gudjonsson Urban Gullberg Arnaldur Gylfason Bjarni V Halldorsson Markus Hansson Hilma Holm Åsa Johansson Ellinor Johnsson Aslaug Jonasdottir Bjorn R Ludviksson Asmundur Oddsson Isleifur Olafsson Sigurgeir Olafsson Olof Sigurdardottir Asgeir Sigurdsson Lilja Stefansdottir Gisli Masson Patrick Sulem Manfred Wuhrer Anna-Karin Wihlborg Gudmar Thorleifsson Daniel F Gudbjartsson Unnur Thorsteinsdottir Gestur Vidarsson Ingileif Jonsdottir Björn Nilsson Kari Stefansson

Nat Genet 2017 Aug 19;49(8):1182-1191. Epub 2017 Jun 19.

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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August 2017

Reproductive fitness and genetic risk of psychiatric disorders in the general population.

Authors:
Niamh Mullins Andrés Ingason Heather Porter Jack Euesden Alexandra Gillett Sigurgeir Ólafsson Daniel F Gudbjartsson Cathryn M Lewis Engilbert Sigurdsson Evald Saemundsen Ólafur Ó Gudmundsson Michael L Frigge Augustine Kong Agnar Helgason G Bragi Walters Omar Gustafsson Hreinn Stefansson Kari Stefansson

Nat Commun 2017 06 13;8:15833. Epub 2017 Jun 13.

deCODE genetics, 101 Reykjavik, Iceland.

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June 2017

Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis.

Authors:
Snaevar Sigurdsson Kristjan F Alexandersson Patrick Sulem Bjarke Feenstra Steinunn Gudmundsdottir Gisli H Halldorsson Sigurgeir Olafsson Asgeir Sigurdsson Thorunn Rafnar Thorgeir Thorgeirsson Erik Sørensen Andreas Nordholm-Carstensen Jakob Burcharth Jens Andersen Henrik Stig Jørgensen Emma Possfelt-Møller Henrik Ullum Gudmar Thorleifsson Gisli Masson Unnur Thorsteinsdottir Mads Melbye Daniel F Gudbjartsson Tryggvi Stefansson Ingileif Jonsdottir Kari Stefansson

Nat Commun 2017 06 6;8:15789. Epub 2017 Jun 6.

deCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.

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June 2017

Polygenic risk scores for schizophrenia and bipolar disorder associate with addiction.

Authors:
Gunnar W Reginsson Andres Ingason Jack Euesden Gyda Bjornsdottir Sigurgeir Olafsson Engilbert Sigurdsson Hogni Oskarsson Thorarinn Tyrfingsson Valgerdur Runarsdottir Ingunn Hansdottir Stacy Steinberg Hreinn Stefansson Daniel F Gudbjartsson Thorgeir E Thorgeirsson Kari Stefansson

Addict Biol 2018 01 23;23(1):485-492. Epub 2017 Feb 23.

deCODE genetics/Amgen, Iceland.

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January 2018

A sequence variant associating with educational attainment also affects childhood cognition.

Authors:
Bjarni Gunnarsson Guðrún A Jónsdóttir Gyða Björnsdóttir Bettina Konte Patrick Sulem Snædís Kristmundsdóttir Birte Kehr Ómar Gústafsson Hannes Helgason Paul D Iordache Sigurgeir Ólafsson Michael L Frigge Guðmar Þorleifsson Sunna Arnarsdóttir Berglind Stefánsdóttir Ina Giegling Srdjan Djurovic Kjetil S Sundet Thomas Espeseth Ingrid Melle Annette M Hartmann Unnur Thorsteinsdottir Augustine Kong Daníel F Guðbjartsson Ulrich Ettinger Ole A Andreassen Dan Rujescu Jónas G Halldórsson Hreinn Stefánsson Bjarni V Halldórsson Kári Stefánsson

Sci Rep 2016 11 4;6:36189. Epub 2016 Nov 4.

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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November 2016