Publications by authors named "Sigurd Lax"

75Publications

Post-mortem viral dynamics and tropism in COVID-19 patients in correlation with organ damage.

Virchows Arch 2020 Aug 20. Epub 2020 Aug 20.

Department of Pathology, Hospital Graz II, Academic Teaching Hospital of the Medical University of Graz, Goestingerstrasse 22, AT-8020, Graz, Austria.

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http://dx.doi.org/10.1007/s00428-020-02903-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438212PMC
August 2020

Pulmonary arterial thrombosis as an important complication of COVID-19 pulmonary disease: letter to the editor.

Virchows Arch 2020 09;477(3):467-468

Division of Gastroenterology and Hepatology with Intensive Care 13H1, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00428-020-02896-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414898PMC
September 2020

Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor-positive Early Breast Cancer: Results from the ABCSG Trial 5.

Clin Cancer Res 2020 Jun 16. Epub 2020 Jun 16.

Institute of Cancer Research, Department of Medicine I, Breast Health Center and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1158/1078-0432.CCR-20-0673DOI Listing
June 2020

The clinical, morphological, and genetic heterogeneity of endometrial stromal sarcoma.

Virchows Arch 2020 04 28;476(4):489-490. Epub 2020 Jan 28.

Department of Pathology, Hospital Graz II, Graz, Austria.

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http://dx.doi.org/10.1007/s00428-020-02762-3DOI Listing
April 2020

Interdisciplinary Diagnosis, Therapy and Follow-up of Patients with Endometrial Cancer. Guideline (S3-Level, AWMF Registry Number 032/034-OL, April 2018) - Part 2 with Recommendations on the Therapy and Follow-up of Endometrial Cancer, Palliative Care, Psycho-oncological/Psychosocial Care/Rehabilitation/Patient Information and Healthcare Facilities.

Geburtshilfe Frauenheilkd 2018 Nov 26;78(11):1089-1109. Epub 2018 Nov 26.

Klinik für Gynäkologie und Geburtshilfe, Universitätsmedizin Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1055/a-0715-2964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261739PMC
November 2018

Pharmacologic IL-6Rα inhibition in cholangiocarcinoma promotes cancer cell growth and survival.

Biochim Biophys Acta Mol Basis Dis 2019 02 9;1865(2):308-321. Epub 2018 Nov 9.

Diagnostic & Research Center for Molecular BioMedicine, Institute of Pathology, Medical University of Graz, Austria; Center for Biomarker Research in Medicine, Graz, Austria; Department of Pathology, Medical Faculty, Otto von Guericke University Magdeburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439183045
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http://dx.doi.org/10.1016/j.bbadis.2018.11.006DOI Listing
February 2019

Can the classification of low-grade endometrial stromal tumors still be improved?

Virchows Arch 2018 Dec 26;473(6):663-664. Epub 2018 Oct 26.

Department of Pathology, Hospital Graz Sued-West, Goestingerstrasse 22, Graz, Austria.

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http://link.springer.com/10.1007/s00428-018-2474-2
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http://dx.doi.org/10.1007/s00428-018-2474-2DOI Listing
December 2018

Interdisciplinary Diagnosis, Therapy and Follow-up of Patients with Endometrial Cancer. Guideline (S3-Level, AWMF Registry Nummer 032/034-OL, April 2018) - Part 1 with Recommendations on the Epidemiology, Screening, Diagnosis and Hereditary Factors of Endometrial Cancer.

Geburtshilfe Frauenheilkd 2018 Oct 19;78(10):949-971. Epub 2018 Oct 19.

Klinik für Gynäkologie und Geburtshilfe, Universitätsmedizin Göttingen, Göttingen, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0713-1218
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http://dx.doi.org/10.1055/a-0713-1218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195426PMC
October 2018

BRCA1 and BRCA2 mRNA-expression prove to be of clinical impact in ovarian cancer.

Br J Cancer 2018 09 15;119(6):683-692. Epub 2018 Aug 15.

Department of Obstetrics and Gynecology, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1038/s41416-018-0217-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173779PMC
September 2018

Miniseries of reviews: gynecological pathology.

Authors:
Sigurd F Lax

Virchows Arch 2018 06;472(6):883-884

Department of Pathology, Hospital Graz Süd-West, Göstingerstrasse 22, AT-8020, Graz, Austria.

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http://link.springer.com/10.1007/s00428-018-2385-2
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http://dx.doi.org/10.1007/s00428-018-2385-2DOI Listing
June 2018

The central role of the pathologist in the management of patients with cervical cancer: ESGO/ESTRO/ESP guidelines.

Virchows Arch 2018 Jul 24;473(1):45-54. Epub 2018 May 24.

Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK.

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http://link.springer.com/10.1007/s00428-018-2372-7
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http://dx.doi.org/10.1007/s00428-018-2372-7DOI Listing
July 2018

and mutation status associates with and expression in ovarian cancer.

Oncotarget 2018 Apr 3;9(25):17501-17511. Epub 2018 Apr 3.

Department of Obstetrics and Gynecology, Medical University of Innsbruck, Innsbruck 6020, Austria.

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http://www.oncotarget.com/fulltext/24770
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http://dx.doi.org/10.18632/oncotarget.24770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915132PMC
April 2018

International Society of Gynecological Pathologists (ISGyP) Endometrial Cancer Project: Guidelines From the Special Techniques and Ancillary Studies Group.

Int J Gynecol Pathol 2019 Jan;38 Suppl 1:S114-S122

MD Anderson Cancer Center, Houston, Texas (R.B., A.Y., A.M.) University of Michigan Medical School, Ann Arbor, Michigan (K.R.C.) Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania (K.C.) Bergonie Institute, Bordeaux, France (S.C.) The Ottawa Hospital, University of Ottawa, Ottawa (B.D.) Toronto General Hospital, Toronto (P.S., B.C.), Ontario Department of Pathology, University of Calgary, Calgary, Alberta (M.K.), Canada Edinburgh Cancer Research Centre, Edinburgh (S.H.) Belfast Health and Social Care Trust, Belfast (W.G.M.), UK Brigham and Women's Hospital (B.H., B.J.Q.) Massachusetts General Hospital, Harvard University (E.O.), Boston, Massachusetts Yale New Haven Hospital, New Haven, Connecticut (P.H., V.P.) Department of Pathology, University of Hong Kong, Hong Kong, China (P.I.) Department of Pathology, Medical University of Graz, Graz, Austria (S.L.) Bellvitge University Hospital, IDIBELL, Barcelona (A.V., X.M.G.) Hospital Universitari Arnau de Vilanova, University of Lleida, IRBLLEIDA, Lleida (X.M.G.), CIBERONC, Spain Weill Cornell Medical College, New York, New York (L.H.E.) Stanford University Medical Center, Stanford, California (T.A.L.) Johns Hopkins University School of Medicine, Baltimore, Maryland (I.M.S.).

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http://dx.doi.org/10.1097/PGP.0000000000000496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296838PMC
January 2019

Metastatic cutaneous apocrine adenocarcinoma responsive to the programmed cell death protein 1 inhibitor pembrolizumab.

Eur J Cancer 2018 02 11;90:146-148. Epub 2017 Dec 11.

Dermatology Clinic, Maggiore Hospital, University of Trieste, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.11.008DOI Listing
February 2018

Rapid response of metastatic cutaneous squamous cell carcinoma to pembrolizumab in a patient with xeroderma pigmentosum: Case report and review of the literature.

Eur J Cancer 2017 09 19;83:99-102. Epub 2017 Jul 19.

Department of Dermatology, Medical University of Graz, Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.06.022DOI Listing
September 2017

Second Opinion Expert Pathology in Endometrial Cancer: Potential Clinical Implications.

Int J Gynecol Cancer 2017 02;27(2):289-296

*Department of Women's Health, Tübingen University Hospital, Tübingen, Germany, †BC Cancer Agency & Department of Pathology, Vancouver General Hospital, Vancouver, Canada, ‡Institute of Pathology, LKH Graz Sued-West, Graz, Austria; and §Institute of Pathology, Tübingen University Hospital, Tübingen, Germany.

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http://dx.doi.org/10.1097/IGC.0000000000000870DOI Listing
February 2017

Pathology of Endometrial Carcinoma.

Authors:
Sigurd F Lax

Adv Exp Med Biol 2017 ;943:75-96

Department of Pathology, Hospital Graz Süd-West, Academic Teaching Hospital of the Medical University Graz, Göstingerstrasse 22, 8020, Graz, Austria.

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http://dx.doi.org/10.1007/978-3-319-43139-0_3DOI Listing
September 2017

L1CAM: amending the "low-risk" category in endometrial carcinoma.

J Cancer Res Clin Oncol 2017 Feb 30;143(2):255-262. Epub 2016 Sep 30.

Department für Frauengesundheit, Universitätsklinikum Tübingen, Calwerstr. 7, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00432-016-2276-3DOI Listing
February 2017

MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients.

Mol Carcinog 2015 Nov 25;54(11):1442-50. Epub 2014 Sep 25.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/mc.22218DOI Listing
November 2015

A functional germline variant in GLI1 implicates hedgehog signaling in clinical outcome of stage II and III colon carcinoma patients.

Clin Cancer Res 2014 Mar 27;20(6):1687-97. Epub 2014 Jan 27.

Authors' Affiliations: Division of Clinical Oncology, Department of Medicine; Research Unit: Genetic Epidemiology and Pharmacogenetics, Division of Clinical Oncology; Institute of Pathology; Clinical Institute of Medical and Laboratory Diagnostics, Medical University of Graz; Department of Pathology, General Hospital Graz West, Graz; Department of Pathology, General Hospital of Leoben, Leoben, Austria; and Department of Medical Oncology, University Hospital Zuerich, Zuerich, Switzerland.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1517DOI Listing
March 2014

miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor.

J Clin Pathol 2014 Mar 4;67(3):198-203. Epub 2013 Oct 4.

Division of Oncology, Department of Internal Medicine, Medical University of Graz (MUG), , Graz, Austria.

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http://dx.doi.org/10.1136/jclinpath-2013-201904DOI Listing
March 2014

Fever of unknown origin with angina: an atypical presentation of polyangiitis with granulomatosis.

Circulation 2013 Jul;128(3):279-80

Clinical Division of Nephrology, Medical University of Graz, Clinical Division of Nephrology, Auenbruggerplatz 27, 8036 Graz, Austria.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.136754DOI Listing
July 2013

Targeting signaling pathways in epithelial ovarian cancer.

Int J Mol Sci 2013 May 2;14(5):9536-55. Epub 2013 May 2.

Institute of Pathology, Medical University Graz, Auenbruggerplatz 25, A-8036 Graz, Austria.

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http://dx.doi.org/10.3390/ijms14059536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676798PMC
May 2013

Toward an improved definition of the tumor spectrum associated with BAP1 germline mutations.

J Clin Oncol 2012 Nov 1;30(32):e337-40. Epub 2012 Oct 1.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, Box 20, New York, NY 10065, USA.

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http://dx.doi.org/10.1200/JCO.2011.41.2965DOI Listing
November 2012

Analysis of functional germline polymorphisms for prediction of response to anthracycline-based neoadjuvant chemotherapy in breast cancer.

Mol Genet Genomics 2012 Sep 18;287(9):755-64. Epub 2012 Aug 18.

Research Unit, Genetic Epidemiology and Pharmacogenetics in Oncology, Division of Clinical Oncology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.

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http://dx.doi.org/10.1007/s00438-012-0715-7DOI Listing
September 2012

Histopathology of cervical precursor lesions and cancer.

Authors:
Sigurd Lax

Acta Dermatovenerol Alp Pannonica Adriat 2011 Sep;20(3):125-33

Department of Pathology, Graz West General Hospital, Austria.

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September 2011

CYP1B1 is not a major determinant of the disposition of aromatase inhibitors in epithelial cells of invasive ductal carcinoma.

Drug Metab Dispos 2008 May 6;36(5):963-70. Epub 2008 Feb 6.

W. Harry Feinstone Center for Genomic Research, University of Memphis, 201 Life Sciences Building, Memphis, TN 38152, USA.

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http://dx.doi.org/10.1124/dmd.107.018960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587047PMC
May 2008

Molecular genetic changes in epithelial, stromal and mixed neoplasms of the endometrium.

Authors:
Sigurd F Lax

Pathology 2007 Feb;39(1):46-54

Department of Pathology, General Hospital Graz West, Graz, Austria.

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http://pdfs.journals.lww.com/pathologyrcpa/2007/39010/Molecu
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http://linkinghub.elsevier.com/retrieve/pii/S003130251633824
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http://dx.doi.org/10.1080/00313020601146822DOI Listing
February 2007

Change of HER-2/neu status in a subset of distant metastases from breast carcinomas.

J Pathol 2004 Aug;203(4):918-26

Department of Pathology, Medical University of Graz, Austria.

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http://dx.doi.org/10.1002/path.1592DOI Listing
August 2004

Bilateral carcinomas of the breast with local recurrence: analysis of genetic relationship of the tumors.

Mod Pathol 2004 May;17(5):597-602

Department of Pathology, Division of Medical Oncology, Medical University of Graz, Austria.

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http://dx.doi.org/10.1038/modpathol.3800089DOI Listing
May 2004

Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification.

Authors:
Sigurd F Lax

Virchows Arch 2004 Mar 28;444(3):213-23. Epub 2004 Jan 28.

Department of Pathology, General Hospital Graz West, Goestingerstrasse 22, 8020 Graz, Austria.

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http://dx.doi.org/10.1007/s00428-003-0947-3DOI Listing
March 2004

Accuracy of frozen section examination of pelvic lymph nodes in patients with FIGO stage IB1 to IIB cervical cancer.

Gynecol Oncol 2003 Sep;90(3):605-9

Department of Obstetrics and Gynecology, University of Graz, Graz A-8036, Austria.

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http://dx.doi.org/10.1016/s0090-8258(03)00398-6DOI Listing
September 2003

Quality assurance for detection of estrogen and progesterone receptors by immunohistochemistry in Austrian pathology laboratories.

Virchows Arch 2002 Oct 17;441(4):328-34. Epub 2002 Sep 17.

Institut für Pathologie der Karl-Franzens Universität Graz, Auenbruggerplatz 25, 8036 Graz, Austria.

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http://dx.doi.org/10.1007/s00428-002-0646-5DOI Listing
October 2002

Microsatellite analysis of breast carcinoma and corresponding local recurrences.

J Pathol 2002 Oct;198(2):190-7

Department of Pathology, University of Graz, Auenbrugger Platz 25, A-8036 Graz, Austria.

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http://dx.doi.org/10.1002/path.1193DOI Listing
October 2002

Inguinal lymph node metastasis as the presenting symptom of endometrial cancer: a case report.

Anticancer Res 2002 Jul-Aug;22(4):2531-2

The Department of Obstetrics and Gynecology, University of Graz, Austria.

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September 2002

Groin recurrence after micrometastasis in a sentinel lymph node in a patient with vulvar cancer.

Gynecol Oncol 2002 Jul;86(1):99-101

Department of Obstetrics and Gynecology, University of Graz, Austria.

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http://dx.doi.org/10.1006/gyno.2002.6727DOI Listing
July 2002