Publications by authors named "Si Ming Man"

64Publications

Bacillus cereus: Epidemiology, Virulence Factors, and Host-Pathogen Interactions.

Trends Microbiol 2020 Sep 28. Epub 2020 Sep 28.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.tim.2020.09.003DOI Listing
September 2020

Publisher Correction: Captain GBP1: inflammasomes assemble, pyroptotic endgame.

Nat Immunol 2020 Nov;21(11):1470

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.1038/s41590-020-00804-1DOI Listing
November 2020

Molecular mechanisms activating the NAIP-NLRC4 inflammasome: Implications in infectious disease, autoinflammation, and cancer.

Immunol Rev 2020 Sep 29;297(1):67-82. Epub 2020 Jul 29.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.1111/imr.12906DOI Listing
September 2020

Captain GBP1: inflammasomes assemble, pyroptotic endgame.

Nat Immunol 2020 08;21(8):829-830

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.1038/s41590-020-0727-0DOI Listing
August 2020

Gasdermins deliver a deadly punch to cancer.

Cell Res 2020 06;30(6):463-464

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, ACT, Canberra, Australia.

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http://dx.doi.org/10.1038/s41422-020-0316-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264324PMC
June 2020

Emerging Activators and Regulators of Inflammasomes and Pyroptosis.

Trends Immunol 2019 11 29;40(11):1035-1052. Epub 2019 Oct 29.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.09.005DOI Listing
November 2019

DDX3X: stressing the NLRP3 inflammasome.

Cell Res 2019 12;29(12):969-970

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, 2601, ACT, Australia.

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http://dx.doi.org/10.1038/s41422-019-0250-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951334PMC
December 2019

Inflammasomes in Colitis and Colorectal Cancer: Mechanism of Action and Therapies.

Yale J Biol Med 2019 09 20;92(3):481-498. Epub 2019 Sep 20.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747943PMC
September 2019

IL-1 Family Members Mediate Cell Death, Inflammation and Angiogenesis in Retinal Degenerative Diseases.

Front Immunol 2019 16;10:1618. Epub 2019 Jul 16.

The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.3389/fimmu.2019.01618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646526PMC
October 2020

A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome.

Nat Microbiol 2019 02 10;4(2):362-374. Epub 2018 Dec 10.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia.

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http://dx.doi.org/10.1038/s41564-018-0318-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685251PMC
February 2019

ALPK1: innate attraction to the sweetness of bacteria.

Cell Res 2018 12;28(12):1125-1126

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.1038/s41422-018-0100-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274639PMC
December 2018

Cytosolic Recognition of Microbes and Pathogens: Inflammasomes in Action.

Microbiol Mol Biol Rev 2018 12 12;82(4). Epub 2018 Sep 12.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia

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http://dx.doi.org/10.1128/MMBR.00015-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298609PMC
December 2018

Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis.

Authors:
Si Ming Man

Nat Rev Gastroenterol Hepatol 2018 12;15(12):721-737

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia.

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http://www.nature.com/articles/s41575-018-0054-1
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http://dx.doi.org/10.1038/s41575-018-0054-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097092PMC
December 2018

Mechanisms of Gasdermin Family Members in Inflammasome Signaling and Cell Death.

J Mol Biol 2018 09 7;430(18 Pt B):3068-3080. Epub 2018 Jul 7.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.07.002DOI Listing
September 2018

Mechanisms and functions of guanylate-binding proteins and related interferon-inducible GTPases: Roles in intracellular lysis of pathogens.

Cell Microbiol 2017 12 19;19(12). Epub 2017 Oct 19.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, Australian National University, Canberra, Australia.

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http://dx.doi.org/10.1111/cmi.12791DOI Listing
December 2017

Molecular mechanisms of inflammasome signaling.

J Leukoc Biol 2018 02 29;103(2):233-257. Epub 2017 Dec 29.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, Australian National University, Canberra, Australia.

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http://dx.doi.org/10.1189/jlb.3MR0617-250RDOI Listing
February 2018

NLRP9b: a novel RNA-sensing inflammasome complex.

Cell Res 2017 11 21;27(11):1302-1303. Epub 2017 Jul 21.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, Australian National University, Canberra, 2601, Australia.

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http://dx.doi.org/10.1038/cr.2017.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674164PMC
November 2017

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.

Immunol Rev 2017 05;277(1):61-75

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/imr.12534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416822PMC
May 2017

Differential roles of caspase-1 and caspase-11 in infection and inflammation.

Sci Rep 2017 03 27;7:45126. Epub 2017 Mar 27.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/srep45126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366862PMC
March 2017

Inflammasomes and Cancer.

Cancer Immunol Res 2017 02 16;5(2):94-99. Epub 2017 Jan 16.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1158/2326-6066.CIR-16-0269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593081PMC
February 2017

Regulation of lysosomal dynamics and autophagy by CTSB/cathepsin B.

Autophagy 2016 12 27;12(12):2504-2505. Epub 2016 Oct 27.

a Department of Immunology , St. Jude Children's Research Hospital , Memphis , TN , USA.

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http://dx.doi.org/10.1080/15548627.2016.1239679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173259PMC
December 2016

Interferon-inducible guanylate-binding proteins at the interface of cell-autonomous immunity and inflammasome activation.

J Leukoc Biol 2017 01 14;101(1):143-150. Epub 2016 Jul 14.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA

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http://dx.doi.org/10.1189/jlb.4MR0516-223RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608036PMC
January 2017

DOCK2 confers immunity and intestinal colonization resistance to Citrobacter rodentium infection.

Sci Rep 2016 06 13;6:27814. Epub 2016 Jun 13.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/srep27814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904218PMC
June 2016

DNA-sensing inflammasomes: regulation of bacterial host defense and the gut microbiota.

Pathog Dis 2016 Jun 6;74(4):ftw028. Epub 2016 Apr 6.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105-3678, USA

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http://dx.doi.org/10.1093/femspd/ftw028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985483PMC
June 2016

Type I Interferon Keeps IL-1β in Check.

Cell Host Microbe 2016 Mar;19(3):272-4

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2016.02.015DOI Listing
March 2016

Converging roles of caspases in inflammasome activation, cell death and innate immunity.

Nat Rev Immunol 2016 Jan 14;16(1):7-21. Epub 2015 Dec 14.

Department of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1038/nri.2015.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915362PMC
January 2016

AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity.

Eur J Immunol 2016 Feb 28;46(2):269-80. Epub 2015 Dec 28.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1002/eji.201545839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758349PMC
February 2016

Gasdermin D: the long-awaited executioner of pyroptosis.

Cell Res 2015 Nov 20;25(11):1183-4. Epub 2015 Oct 20.

Department of Immunology, St. Jude Children's Research Hospital, MS #351, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1038/cr.2015.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650426PMC
November 2015

Global Epidemiology of Campylobacter Infection.

Clin Microbiol Rev 2015 Jul;28(3):687-720

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, Australia Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA

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http://dx.doi.org/10.1128/CMR.00006-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462680PMC
July 2015

A20 is a regulator of necroptosis.

Nat Immunol 2015 Jun;16(6):596-7

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1038/ni.3174DOI Listing
June 2015

Is Campylobacter to esophageal adenocarcinoma as Helicobacter is to gastric adenocarcinoma?

Trends Microbiol 2015 Aug 27;23(8):455-62. Epub 2015 Apr 27.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney 2052, NSW, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S0966842X150007
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http://dx.doi.org/10.1016/j.tim.2015.03.009DOI Listing
August 2015

Regulation of inflammasome activation.

Immunol Rev 2015 May;265(1):6-21

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/imr.12296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400844PMC
May 2015

Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection.

Cell Host Microbe 2015 Mar 19;17(3):357-368. Epub 2015 Feb 19.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359672PMC
March 2015

Transcriptomic and proteomic analyses reveal key innate immune signatures in the host response to the gastrointestinal pathogen Campylobacter concisus.

Infect Immun 2015 Feb 8;83(2):832-45. Epub 2014 Dec 8.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1128/IAI.03012-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294260PMC
February 2015

Role of emerging Campylobacter species in inflammatory bowel diseases.

Inflamm Bowel Dis 2014 Nov;20(11):2189-97

*School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, Australia; and †Department of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1097/MIB.0000000000000074DOI Listing
November 2014

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

Proc Natl Acad Sci U S A 2014 May 6;111(20):7403-8. Epub 2014 May 6.

Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1402911111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034195PMC
May 2014

Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection.

Proc Natl Acad Sci U S A 2014 Jan 17;111(1):385-90. Epub 2013 Dec 17.

Department of Immunology and Animal Resources Center and the Veterinary Pathology Core, St. Jude Children's Research Hospital, Memphis, TN 38105.

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http://dx.doi.org/10.1073/pnas.1317643111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890849PMC
January 2014

Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production.

J Immunol 2013 Nov 11;191(10):5239-46. Epub 2013 Oct 11.

Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1301581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835177PMC
November 2013

Functional relationship between Campylobacter concisus and the stomach ecosystem in health and disease.

ISME J 2013 Dec 4;7(12):2245-7. Epub 2013 Jul 4.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1038/ismej.2013.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834848PMC
December 2013

Bacterial infection of macrophages induces decrease in refractive index.

J Biophotonics 2013 May 6;6(5):393-7. Epub 2012 Aug 6.

Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/jbio.201200113DOI Listing
May 2013

The clinical importance of emerging Campylobacter species.

Authors:
Si Ming Man

Nat Rev Gastroenterol Hepatol 2011 Oct 25;8(12):669-85. Epub 2011 Oct 25.

Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

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http://dx.doi.org/10.1038/nrgastro.2011.191DOI Listing
October 2011

Downloads: Stats for papers let authors track impact.

Authors:
Si Ming Man

Nature 2011 Aug 24;476(7361):399. Epub 2011 Aug 24.

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http://dx.doi.org/10.1038/476399dDOI Listing
August 2011

The role of bacteria and pattern-recognition receptors in Crohn's disease.

Nat Rev Gastroenterol Hepatol 2011 Mar 8;8(3):152-68. Epub 2011 Feb 8.

Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

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http://dx.doi.org/10.1038/nrgastro.2011.3DOI Listing
March 2011

The internal transcribed spacer region, a new tool for use in species differentiation and delineation of systematic relationships within the Campylobacter genus.

Appl Environ Microbiol 2010 May 26;76(10):3071-81. Epub 2010 Mar 26.

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1128/AEM.02551-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869123PMC
May 2010

The secretome of Campylobacter concisus.

FEBS J 2010 Apr 10;277(7):1606-17. Epub 2010 Feb 10.

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07587.xDOI Listing
April 2010

Campylobacter concisus and other Campylobacter species in children with newly diagnosed Crohn's disease.

Inflamm Bowel Dis 2010 Jun;16(6):1008-16

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1002/ibd.21157DOI Listing
June 2010

Detection and isolation of Campylobacter species other than C. jejuni from children with Crohn's disease.

J Clin Microbiol 2009 Feb 3;47(2):453-5. Epub 2008 Dec 3.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, Australia.

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http://dx.doi.org/10.1128/JCM.01949-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643684PMC
February 2009

Detection of enterohepatic and gastric helicobacter species in fecal specimens of children with Crohn's disease.

Helicobacter 2008 Aug;13(4):234-8

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/j.1523-5378.2008.00607.xDOI Listing
August 2008