Publications by authors named "Shuwen Liu"

100Publications

A novel selective histone deacetylase I inhibitor CC-4a activates latent HIV-1 through NF-κB pathway.

Life Sci 2020 Sep 14:118427. Epub 2020 Sep 14.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Southern Medical University, Guangzhou 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2020.118427DOI Listing
September 2020

Efficacy and mechanism of actions of natural antimicrobial drugs.

Pharmacol Ther 2020 Sep 8:107671. Epub 2020 Sep 8.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Southern Medical University, Guangzhou 510515, China.. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2020.107671DOI Listing
September 2020

Natural Product Luteolin Rescues THAP-Induced Pancreatic β-Cell Dysfunction through HNF4α Pathway.

Am J Chin Med 2020 Sep 9:1-20. Epub 2020 Sep 9.

State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, P. R. China.

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http://dx.doi.org/10.1142/S0192415X20500706DOI Listing
September 2020

Structure-aided optimization of 3-O-β-chacotriosyl epiursolic acid derivatives as novel H5N1 virus entry inhibitors.

Bioorg Med Chem Lett 2020 Aug 31;30(22):127518. Epub 2020 Aug 31.

College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2020.127518DOI Listing
August 2020

Differentiating diagnosis of COVID-19 or influenza in patients based on laboratory data during flu season.

EClinicalMedicine 2020 Sep 25;26:100511. Epub 2020 Aug 25.

Haid Research Institute, Guangdong Haid Group Co., Ltd, 5 Eighth Street, Fu Ping Road, Guangzhou 511400, PR China.

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http://dx.doi.org/10.1016/j.eclinm.2020.100511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445122PMC
September 2020

Luteolin Protects Against CIRI, Potentially via Regulation of the SIRT3/AMPK/mTOR Signaling Pathway.

Neurochem Res 2020 Aug 18. Epub 2020 Aug 18.

Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, 130021, People's Republic of China.

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http://dx.doi.org/10.1007/s11064-020-03108-wDOI Listing
August 2020

SNW1 interacts with IKKγ to positively regulate antiviral innate immune responses against influenza A virus infection.

Microbes Infect 2020 Aug 14. Epub 2020 Aug 14.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, PR China; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Southern Medical University, Guangzhou, 510515, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2020.07.009DOI Listing
August 2020

Potential treatment methods targeting 2019-nCoV infection.

Eur J Med Chem 2020 Jul 28;205:112687. Epub 2020 Jul 28.

Guangdong Provincial Key Laboratory of New Drug Screening and Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385720PMC
July 2020

Yeast Assimilable Nitrogen Concentrations Influence Yeast Gene Expression and Hydrogen Sulfide Production During Cider Fermentation.

Front Microbiol 2020 24;11:1264. Epub 2020 Jun 24.

Horticulture Section, School of Integrative Plant Science, Cornell University, Ithaca, NY, United States.

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http://dx.doi.org/10.3389/fmicb.2020.01264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326769PMC
June 2020

Discovery of Novel Resorcinol Dibenzyl Ethers Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction as Potential Anticancer Agents.

J Med Chem 2020 Aug 30;63(15):8338-8358. Epub 2020 Jul 30.

School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou 510515, China.

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http://dx.doi.org/10.1021/acs.jmedchem.0c00574DOI Listing
August 2020

Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.

Eur J Med Chem 2020 Sep 27;202:112519. Epub 2020 Jun 27.

School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112519DOI Listing
September 2020

Bone-Targeting Prodrug Mesoporous Silica-Based Nanoreactor with Reactive Oxygen Species Burst for Enhanced Chemotherapy.

ACS Appl Mater Interfaces 2020 Aug 21;12(31):34630-34642. Epub 2020 Jul 21.

School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou 510515, China.

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http://dx.doi.org/10.1021/acsami.0c08992DOI Listing
August 2020

RGD-PEG-PLA Delivers MiR-133 to Infarct Lesions of Acute Myocardial Infarction Model Rats for Cardiac Protection.

Pharmaceutics 2020 Jun 21;12(6). Epub 2020 Jun 21.

Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.

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http://dx.doi.org/10.3390/pharmaceutics12060575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356814PMC
June 2020

Dihydromyricetin is a new inhibitor of influenza polymerase PB2 subunit and influenza-induced inflammation.

Microbes Infect 2020 Jul - Aug;22(6-7):254-262. Epub 2020 Jun 15.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2020.05.021DOI Listing
June 2020

Metabolism and Toxicity of Emodin: Genome-Wide Association Studies Reveal Hepatocyte Nuclear Factor 4α Regulates UGT2B7 and Emodin Glucuronidation.

Chem Res Toxicol 2020 Jul 7;33(7):1798-1808. Epub 2020 Jul 7.

State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Southern Medical University, Guangzhou 510515, China.

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http://dx.doi.org/10.1021/acs.chemrestox.0c00047DOI Listing
July 2020

A series of octahydroquinazoline-5-ones as novel inhibitors against dengue virus.

Eur J Med Chem 2020 Aug 11;200:112318. Epub 2020 May 11.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North Guangzhou, 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112318DOI Listing
August 2020

Tolcapone Potently Inhibits Seminal Amyloid Fibrils Formation and Blocks Entry of Ebola Pseudoviruses.

Front Microbiol 2020 30;11:504. Epub 2020 Apr 30.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.3389/fmicb.2020.00504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203225PMC
April 2020

Discovery of dihydropyrrolidones as novel inhibitors against influenza A virus.

Eur J Med Chem 2020 Aug 4;199:112334. Epub 2020 May 4.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112334DOI Listing
August 2020

Comparative review of respiratory diseases caused by coronaviruses and influenza A viruses during epidemic season.

Microbes Infect 2020 Jul - Aug;22(6-7):236-244. Epub 2020 May 13.

Laboratory of Molecular Virology & Immunology, Technology Innovation Center, Haid Research Institute, Guangdong Haid Group Co., Ltd, Guangzhou, 511400, China. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2020.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217786PMC
August 2020

Kinase inhibitor roscovitine as a PB2 cap-binding inhibitor against influenza a virus replication.

Biochem Biophys Res Commun 2020 Jun 13;526(4):1143-1149. Epub 2020 Apr 13.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, PR China; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Southern Medical University, Guangzhou, 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.04.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152910PMC
June 2020

Structure-activity relationship of flavonoid bifunctional inhibitors against Zika virus infection.

Biochem Pharmacol 2020 Jul 6;177:113962. Epub 2020 Apr 6.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2020.113962DOI Listing
July 2020

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion.

Cell Res 2020 Apr 30;30(4):343-355. Epub 2020 Mar 30.

Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan-Jinbo Joint Research Center, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.1038/s41422-020-0305-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104723PMC
April 2020

D-Glucuronic Acid-Coated Ultrasmall Bi₂O₃ Nanoparticles for CT Imaging.

J Nanosci Nanotechnol 2020 Aug;20(8):4638-4642

Department of Chemistry and Department of Nanoscience and Nanotechnology (DNN), College of Natural Sciences, Kyungpook National University (KNU), Taegu 41566, South Korea.

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http://dx.doi.org/10.1166/jnn.2020.17817DOI Listing
August 2020

Novel gel-like Pickering emulsions stabilized solely by hydrophobic starch nanocrystals.

Int J Biol Macromol 2020 Jun 19;152:703-708. Epub 2020 Feb 19.

State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2020.02.175DOI Listing
June 2020

Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein.

Cell Mol Immunol 2020 07 11;17(7):765-767. Epub 2020 Feb 11.

Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan-Jinbo Joint Research Center, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1038/s41423-020-0374-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075278PMC
July 2020

Synthesis and SARs of dopamine derivatives as potential inhibitors of influenza virus PA endonuclease.

Eur J Med Chem 2020 Mar 11;189:112048. Epub 2020 Jan 11.

College of Materials and Energy, South China Agricultural University, Guangzhou, 510642, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112048DOI Listing
March 2020

Antipyretic, anti-inflammatory and analgesic activities of Periplaneta americana extract and underlying mechanisms.

Biomed Pharmacother 2020 Mar 19;123:109753. Epub 2019 Dec 19.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2019.109753DOI Listing
March 2020

GLP-1 Receptor Activation Abrogates β-Cell Dysfunction by PKA Cα-Mediated Degradation of Thioredoxin Interacting Protein.

Front Pharmacol 2019 25;10:1230. Epub 2019 Oct 25.

State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.3389/fphar.2019.01230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824261PMC
October 2019

Resveratrol promotes HSV-2 replication by increasing histone acetylation and activating NF-κB.

Biochem Pharmacol 2020 01 5;171:113691. Epub 2019 Nov 5.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Southern Medical University, Guangzhou 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.113691DOI Listing
January 2020

Key amino acid residues of neuraminidase involved in influenza A virus entry.

Pathog Dis 2019 08;77(6)

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, China.

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http://dx.doi.org/10.1093/femspd/ftz063DOI Listing
August 2019

A Novel CXCR4 Targeting Protein SDF-1/54 as an HIV-1 Entry Inhibitor.

Viruses 2019 09 18;11(9). Epub 2019 Sep 18.

Department of Microbiology, School of Public Health, Southern Medical University, Guangzhou 510515, China.

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http://dx.doi.org/10.3390/v11090874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783869PMC
September 2019

Diastereoselective Synthesis of 3,4-Dihydropyran-3-carboxamides with in Vitro Anti-inflammatory Activity.

ACS Comb Sci 2019 10 11;21(10):656-665. Epub 2019 Sep 11.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , China.

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http://dx.doi.org/10.1021/acscombsci.9b00050DOI Listing
October 2019

Bone sialoprotein-αvβ3 integrin axis promotes breast cancer metastasis to the bone.

Cancer Sci 2019 Oct 5;110(10):3157-3172. Epub 2019 Sep 5.

Department of Medical Research, General Hospital of Southern Theater Command, Guangzhou, China.

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http://dx.doi.org/10.1111/cas.14172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778634PMC
October 2019

N-Substituted Pyrrole Derivative 12m Inhibits HIV-1 Entry by Targeting Gp41 of HIV-1 Envelope Glycoprotein.

Front Pharmacol 2019 2;10:859. Epub 2019 Aug 2.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.3389/fphar.2019.00859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688628PMC
August 2019

Incorporation of privileged structures into 3-O-β-chacotriosyl ursolic acid can enhance inhibiting the entry of the H5N1 virus.

Bioorg Med Chem Lett 2019 09 19;29(18):2675-2680. Epub 2019 Jul 19.

College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.07.028DOI Listing
September 2019

Structure-aided optimization of 3-O-β-chacotriosyl ursolic acid as novel H5N1 entry inhibitors with high selective index.

Bioorg Med Chem 2019 09 19;27(18):4048-4058. Epub 2019 Jul 19.

College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.07.028DOI Listing
September 2019

A seamless and iterative DNA assembly method named PS-Brick and its assisted metabolic engineering for threonine and 1-propanol production.

Biotechnol Biofuels 2019 15;12:180. Epub 2019 Jul 15.

1CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101 China.

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http://dx.doi.org/10.1186/s13068-019-1520-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628500PMC
July 2019

Exploring the Natural Piericidins as Anti-Renal Cell Carcinoma Agents Targeting Peroxiredoxin 1.

J Med Chem 2019 08 25;62(15):7058-7069. Epub 2019 Jul 25.

Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography , University of California at San Diego , La Jolla , California 92093 , United States.

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https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00598
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http://dx.doi.org/10.1021/acs.jmedchem.9b00598DOI Listing
August 2019

[A non-coated enzyme-linked immunosorbent assay for screening zika virus envelope protein].

Nan Fang Yi Ke Da Xue Xue Bao 2019 Jun;39(6):699-704

School of Pharmaceutical Sciences, Guangdong Provincial Key Lab of Drug Screening, Guangzhou Key Lab of Drug Research for Emerging Virus Prevention and Treatment, Guangzhou 510515, China.

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http://dx.doi.org/10.12122/j.issn.1673-4254.2019.06.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743923PMC
June 2019

TLR1/2 Specific Small-Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes.

Adv Sci (Weinh) 2019 May 27;6(10):1802042. Epub 2019 Mar 27.

Guangdong Provincial Key Laboratory of New Drug Screening and Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment School of Pharmaceutical Sciences Southern Medical University Guangzhou 510515 China.

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http://dx.doi.org/10.1002/advs.201802042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523386PMC
May 2019

Investigational antiviral therapies for the treatment of influenza.

Expert Opin Investig Drugs 2019 05 24;28(5):481-488. Epub 2019 Apr 24.

a Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou , China.

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http://dx.doi.org/10.1080/13543784.2019.1606210DOI Listing
May 2019

A novel bromodomain inhibitor, CPI-203, serves as an HIV-1 latency-reversing agent by activating positive transcription elongation factor b.

Biochem Pharmacol 2019 06 13;164:237-251. Epub 2019 Apr 13.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952193014
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http://dx.doi.org/10.1016/j.bcp.2019.04.005DOI Listing
June 2019

Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli.

J Struct Biol 2019 06 1;206(3):322-334. Epub 2019 Apr 1.

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Savaid Medical School, University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2019.04.001DOI Listing
June 2019

Motion Control of Polymeric Nanomotors Based on Host-Guest Interactions.

Angew Chem Int Ed Engl 2019 06 20;58(26):8687-8691. Epub 2019 May 20.

Institute for Molecules and Materials, Radboud University, Nijmegen, 6525, AJ, The Netherlands.

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http://dx.doi.org/10.1002/anie.201900917DOI Listing
June 2019

Pharmacokinetic and Pharmacogenetic Factors Contributing to Platelet Function Recovery After Single Dose of Ticagrelor in Healthy Subjects.

Front Pharmacol 2019 18;10:209. Epub 2019 Mar 18.

Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

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https://www.frontiersin.org/article/10.3389/fphar.2019.00209
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http://dx.doi.org/10.3389/fphar.2019.00209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431676PMC
March 2019

Smart nanoplatform for sequential drug release and enhanced chemo-thermal effect of dual drug loaded gold nanorod vesicles for cancer therapy.

J Nanobiotechnology 2019 Mar 27;17(1):44. Epub 2019 Mar 27.

Department of Pharmacy, Nanfang Hospital, School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China.

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http://dx.doi.org/10.1186/s12951-019-0473-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437988PMC
March 2019

ADS-J1 disaggregates semen-derived amyloid fibrils.

Biochem J 2019 03 29;476(6):1021-1035. Epub 2019 Mar 29.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, Guangdong Province, China

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http://www.biochemj.org/lookup/doi/10.1042/BCJ20180886
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http://dx.doi.org/10.1042/BCJ20180886DOI Listing
March 2019

Dual-Analyte Chronopotentiometric Aptasensing Platform Based on a G-Quadruplex/Hemin DNAzyme and Logic Gate Operations.

Anal Chem 2019 02 30;91(4):3170-3176. Epub 2019 Jan 30.

Key Laboratory of Coastal Environmental Processes and Ecological Remediation and Shandong Provincial Key Laboratory of Coastal Environmental Processes , Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS) , Yantai , Shandong 264003 , P. R. China.

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http://dx.doi.org/10.1021/acs.analchem.8b05971DOI Listing
February 2019

Femtomolar Detection of Lipopolysaccharide in Injectables and Serum Samples Using Aptamer-Coupled Reduced Graphene Oxide in a Continuous Injection-Electrostacking Biochip.

Anal Chem 2019 02 8;91(3):2360-2367. Epub 2019 Jan 8.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , China.

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http://dx.doi.org/10.1021/acs.analchem.8b05106DOI Listing
February 2019

Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection.

J Pharmacol Sci 2018 Dec 25;138(4):247-256. Epub 2018 Jun 25.

State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jphs.2018.06.012DOI Listing
December 2018

Potential Blood Pressure Goals in IgA Nephropathy: Prevalence, Awareness, and Treatment Rates in Chronic Kidney Disease Among Patients with Hypertension in China (PATRIOTIC) Study.

Kidney Blood Press Res 2018 30;43(6):1786-1795. Epub 2018 Nov 30.

Department of Nephrology, Chinese People's Liberation Army General Hospital, Chinese People's Liberation Army Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China,

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http://dx.doi.org/10.1159/000495636DOI Listing
February 2019

Spirostaphylotrichin X from a Marine-Derived Fungus as an Anti-influenza Agent Targeting RNA Polymerase PB2.

J Nat Prod 2018 12 5;81(12):2722-2730. Epub 2018 Dec 5.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.8b00656DOI Listing
December 2018

[PSB0739 inhibits formation of semen-derived amyloid fibril].

Nan Fang Yi Ke Da Xue Xue Bao 2018 Nov;38(11):1338-1343

School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.

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http://www.j-smu.com/oa/darticle.aspx?type=view&id=20181
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http://dx.doi.org/10.12122/j.issn.1673-4254.2018.11.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744116PMC
November 2018

AT‑101 induces G1/G0 phase arrest via the β‑catenin/cyclin D1 signaling pathway in human esophageal cancer cells.

Oncol Rep 2019 Feb 20;41(2):1415-1423. Epub 2018 Nov 20.

State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.

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http://www.spandidos-publications.com/10.3892/or.2018.6876
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http://dx.doi.org/10.3892/or.2018.6876DOI Listing
February 2019

Efficient CRISPR-Cas9 mediated multiplex genome editing in yeasts.

Biotechnol Biofuels 2018 10;11:277. Epub 2018 Oct 10.

1CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101 China.

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http://dx.doi.org/10.1186/s13068-018-1271-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180501PMC
October 2018

A new species of Homalota Mannerheim, 1830 (Coleoptera: Staphylinidae: Aleocharinae) from Nanjing, China.

Zootaxa 2018 Jul 10;4444(3):327-332. Epub 2018 Jul 10.

College of Life Sciences, Research Center of Biotechnology, Hebei University, Baoding, 071000, China Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University; College of Forestry, Nanjing Forestry University, Nanjing, 210037, China.

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http://dx.doi.org/10.11646/zootaxa.4444.3.7DOI Listing
July 2018

Emodin-induced hepatotoxicity was exacerbated by probenecid through inhibiting UGTs and MRP2.

Toxicol Appl Pharmacol 2018 11 21;359:91-101. Epub 2018 Sep 21.

Biopharmaceutics, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2018.09.029DOI Listing
November 2018

"On-Water" Synthesis of Quinazolinones and Dihydroquinazolinones Starting from -Bromobenzonitrile.

Molecules 2018 Sep 12;23(9). Epub 2018 Sep 12.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.

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http://dx.doi.org/10.3390/molecules23092325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225144PMC
September 2018

Investigation of the inhibition effect of arachidonic acid on the core structure of the HIV-1 gp41.

J Pharm Biomed Anal 2018 Nov 3;161:377-382. Epub 2018 Sep 3.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07317085183088
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http://dx.doi.org/10.1016/j.jpba.2018.09.006DOI Listing
November 2018

PR-957, a selective immunoproteasome inhibitor, reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1.

Biochem Pharmacol 2018 10 29;156:511-523. Epub 2018 Aug 29.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Southern Medical University, Guangzhou 510515, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952183036
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http://dx.doi.org/10.1016/j.bcp.2018.08.042DOI Listing
October 2018

p21-activated kinase 4 as a switch between caspase-8 apoptosis and NF-κB survival signals in response to TNF-α in hepatocarcinoma cells.

Biochem Biophys Res Commun 2018 09 24;503(4):3003-3010. Epub 2018 Aug 24.

Orthopedics Department, Lanzhou University Second Hospital, Lanzhou, 730030, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.08.085DOI Listing
September 2018

The Role of Toll-Like Receptor in Inflammation and Tumor Immunity.

Front Pharmacol 2018 6;9:878. Epub 2018 Aug 6.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.3389/fphar.2018.00878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088210PMC
August 2018

Current pulse based ion-selective electrodes for chronopotentiometric determination of calcium in seawater.

Anal Chim Acta 2018 Nov 14;1031:67-74. Epub 2018 Jun 14.

Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Shandong Provincial Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai, Shandong, 264003, PR China; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, PR China.

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http://dx.doi.org/10.1016/j.aca.2018.06.018DOI Listing
November 2018

A Small-Molecule Compound Has Anti-influenza A Virus Activity by Acting as a ''PB2 Inhibitor".

Mol Pharm 2018 09 23;15(9):4110-4120. Epub 2018 Aug 23.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , China.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b00531DOI Listing
September 2018

Reconstruction of tricarboxylic acid cycle in Corynebacterium glutamicum with a genome-scale metabolic network model for trans-4-hydroxyproline production.

Biotechnol Bioeng 2019 01 27;116(1):99-109. Epub 2018 Oct 27.

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.1002/bit.26818DOI Listing
January 2019

Inhibition of hyperpolarization-activated cyclic nucleotide-gated channels by β-blocker carvedilol.

Br J Pharmacol 2018 10 9;175(20):3963-3975. Epub 2018 Sep 9.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

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http://doi.wiley.com/10.1111/bph.14469
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http://dx.doi.org/10.1111/bph.14469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151329PMC
October 2018

Structurally Diverse Polyketides From the Mangrove-Derived Fungus sp. SCSIO 41011 With Their Anti-influenza A Virus Activities.

Front Chem 2018 12;6:282. Epub 2018 Jul 12.

CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.

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http://dx.doi.org/10.3389/fchem.2018.00282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052247PMC
July 2018

Evidence of the genetic diversity and clonal population structure of Oenococcus oeni strains isolated from different wine-making regions of China.

J Microbiol 2018 Aug 25;56(8):556-564. Epub 2018 Jul 25.

College of Horticulture, Northwest Agriculture and Forestry University, Shaanxi, 712100, P. R. China.

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http://dx.doi.org/10.1007/s12275-018-7568-7DOI Listing
August 2018

Myricetin antagonizes semen-derived enhancer of viral infection (SEVI) formation and influences its infection-enhancing activity.

Retrovirology 2018 07 16;15(1):49. Epub 2018 Jul 16.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou, 510515, Guangdong, China.

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http://dx.doi.org/10.1186/s12977-018-0432-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048764PMC
July 2018

Gender Differences in the Hepatotoxicity and Toxicokinetics of Emodin: The Potential Mechanisms Mediated by UGT2B7 and MRP2.

Mol Pharm 2018 09 27;15(9):3931-3945. Epub 2018 Jul 27.

State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology , Southern Medical University , Guangzhou 510515 , China.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b00387DOI Listing
September 2018

3-Hydroxyphthalic Anhydride- Modified Rabbit Anti-PAP IgG as a Potential Bifunctional HIV-1 Entry Inhibitor.

Front Microbiol 2018 19;9:1330. Epub 2018 Jun 19.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.3389/fmicb.2018.01330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018217PMC
June 2018

Sulfonated Compounds Bind with Prostatic Acid Phosphatase (PAP) to Inhibit the Formation of Amyloid Fibrils.

ChemistryOpen 2018 Jun 11;7(6):447-456. Epub 2018 Jun 11.

Guangdong Provincial Key Laboratory of New Drug Screening School of Pharmaceutical Sciences Southern Medical University Guangzhou 510515 P.R. China.

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http://dx.doi.org/10.1002/open.201800041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997223PMC
June 2018

Sensitive and specific detection of clinical bacteria via vancomycin-modified FeO@Au nanoparticles and aptamer-functionalized SERS tags.

J Mater Chem B 2018 Jun 25;6(22):3751-3761. Epub 2018 May 25.

Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Beijing 100853, China.

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http://dx.doi.org/10.1039/c8tb00504dDOI Listing
June 2018

Trilobatin as an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope.

FEBS Lett 2018 07 6;592(13):2361-2377. Epub 2018 Jun 6.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

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http://doi.wiley.com/10.1002/1873-3468.13113
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http://dx.doi.org/10.1002/1873-3468.13113DOI Listing
July 2018

Tatanan A from the Acorus calamus L. root inhibited dengue virus proliferation and infections.

Phytomedicine 2018 Mar 15;42:258-267. Epub 2018 Mar 15.

State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.03.018DOI Listing
March 2018

A sensitive colorimetric aptasensor based on trivalent peroxidase-mimic DNAzyme and magnetic nanoparticles.

Anal Chim Acta 2018 Aug 3;1018:86-93. Epub 2018 Feb 3.

State Key Laboratory of Chemical Oncogenomics, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong 518055, China; School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.aca.2018.01.040DOI Listing
August 2018

TMC120 displayed potent cytotoxic effect on human cervical carcinoma through enhancing the polymerization of microtubules.

AIDS 2018 06;32(9):1107-1114

Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences.

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http://dx.doi.org/10.1097/QAD.0000000000001808DOI Listing
June 2018

UGT-mediated metabolism plays a dominant role in the pharmacokinetic behavior and the disposition of morusin in vivo and in vitro.

J Pharm Biomed Anal 2018 May 12;154:339-353. Epub 2018 Mar 12.

State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Southern Medical University, Guangzhou 510515, China; Biopharmaceutics, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.02.062DOI Listing
May 2018

Towards sustainable consumption: A socio-economic analysis of household waste recycling outcomes in Hong Kong.

J Environ Manage 2018 May 13;214:416-425. Epub 2018 Mar 13.

School of Arts and Social Sciences, The Open University of Hong Kong, 7/F, Block A, 30 Good Shepherd Street, Homantin, Kowloon, Hong Kong.

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http://dx.doi.org/10.1016/j.jenvman.2018.03.029DOI Listing
May 2018

Heat shock factor 1 suppresses the HIV-induced inflammatory response by inhibiting nuclear factor-κB.

Cell Immunol 2018 05 31;327:26-35. Epub 2018 Jan 31.

Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Southern Medical University, Guangzhou 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2018.01.015DOI Listing
May 2018

Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice.

J Hepatol 2018 07 8;69(1):51-59. Epub 2018 Mar 8.

State Key Laboratory of Organ Failure Research, Southern Medical University, Guangzhou, China; Guangdong Provincial Key Laboratory of Proteomics, Southern Medical University, Guangzhou, China; Department of Pathophysiology, Southern Medical University, Guangzhou, China; Department of Intensive Care Unit, Zhujiang Hospital, Southern Medical University, Guangzhou, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278183014
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http://dx.doi.org/10.1016/j.jhep.2018.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365016PMC
July 2018

Core-shell assay based aptasensor for sensitive and selective thrombin detection using dark-field microscopy.

Talanta 2018 May 31;182:348-353. Epub 2018 Jan 31.

Institute of Optical Imaging and Sensing, Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, People's Republic of China; Department of Physics, Tsinghua University, Beijing 100084, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2018.01.070DOI Listing
May 2018

A New Strategy Involving the Use of Peptides and Graphene Oxide for Fluorescence Turn-on Detection of Proteins.

Sensors (Basel) 2018 Jan 29;18(2). Epub 2018 Jan 29.

The State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.

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http://dx.doi.org/10.3390/s18020385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855184PMC
January 2018

Reprogramming One-Carbon Metabolic Pathways To Decouple l-Serine Catabolism from Cell Growth in Corynebacterium glutamicum.

ACS Synth Biol 2018 02 19;7(2):635-646. Epub 2018 Jan 19.

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences , Beijing 100101, China.

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http://dx.doi.org/10.1021/acssynbio.7b00373DOI Listing
February 2018

Targeting pattern-recognition receptors to discover new small molecule immune modulators.

Eur J Med Chem 2018 Jan 8;144:82-92. Epub 2017 Dec 8.

Guangdong Provincial Key Laboratory of New Drug Screening and Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.12.026DOI Listing
January 2018

Inhibition of dengue viral infection by diasarone-I is associated with 2'O methyltransferase of NS5.

Eur J Pharmacol 2018 Feb 13;821:11-20. Epub 2017 Dec 13.

State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2017.12.029DOI Listing
February 2018

An oligothiophene compound neutralized influenza A viruses by interfering with hemagglutinin.

Biochim Biophys Acta Biomembr 2018 Mar 8;1860(3):784-791. Epub 2017 Dec 8.

New Drug Screening Key Laboratory of Guangdong Province, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2017.12.006DOI Listing
March 2018

Development and validation of a prognostic nomogram for IgA nephropathy.

Oncotarget 2017 Nov 10;8(55):94371-94381. Epub 2017 Oct 10.

Department of Nephrology, Chinese People's Liberation Army (PLA) General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Beijing, China.

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http://dx.doi.org/10.18632/oncotarget.21721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706880PMC
November 2017

Native promoters of Corynebacterium glutamicum and its application in L-lysine production.

Biotechnol Lett 2018 Feb 21;40(2):383-391. Epub 2017 Nov 21.

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing, 100101, China.

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http://dx.doi.org/10.1007/s10529-017-2479-yDOI Listing
February 2018

A Degraded Fragment of HIV-1 Gp120 in Rat Hepatocytes Forms Fibrils and Enhances HIV-1 Infection.

Biophys J 2017 Oct;113(7):1425-1439

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627148PMC
October 2017

A Novel Tool for Microbial Genome Editing Using the Restriction-Modification System.

ACS Synth Biol 2018 01 12;7(1):98-106. Epub 2017 Oct 12.

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences , Beijing 100101, China.

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http://dx.doi.org/10.1021/acssynbio.7b00254DOI Listing
January 2018

The role of oxidative stress in influenza virus infection.

Microbes Infect 2017 12 14;19(12):580-586. Epub 2017 Sep 14.

Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2017.08.008DOI Listing
December 2017

Andrographolide inhibits influenza A virus-induced inflammation in a murine model through NF-κB and JAK-STAT signaling pathway.

Microbes Infect 2017 12 7;19(12):605-615. Epub 2017 Sep 7.

Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Southern Medical University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2017.08.009DOI Listing
December 2017

A hydrophobic organelle probe based on aggregation-induced emission: Nanosuspension preparation and direct use for endoplasmic reticulum imaging in living cells.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Jan 8;189:231-238. Epub 2017 Aug 8.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, China. Electronic address:

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http://dx.doi.org/10.1016/j.saa.2017.08.016DOI Listing
January 2018

Molecular Dynamics Study to Investigate the Dimeric Structure of the Full-Length α-Synuclein in Aqueous Solution.

J Chem Inf Model 2017 09 22;57(9):2281-2293. Epub 2017 Aug 22.

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University , Guangzhou, 510515, PR China.

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http://dx.doi.org/10.1021/acs.jcim.7b00210DOI Listing
September 2017

Potent influenza A virus entry inhibitors targeting a conserved region of hemagglutinin.

Biochem Pharmacol 2017 11 1;144:35-51. Epub 2017 Aug 1.

Group of Peptides and Natural Products Research, Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.07.023DOI Listing
November 2017