Shreeram Akilesh

Shreeram Akilesh

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Shreeram Akilesh

Shreeram Akilesh

Publications by authors named "Shreeram Akilesh"

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Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

Authors:
Alexander Teumer Yong Li Sahar Ghasemi Bram P Prins Matthias Wuttke Tobias Hermle Ayush Giri Karsten B Sieber Chengxiang Qiu Holger Kirsten Adrienne Tin Audrey Y Chu Nisha Bansal Mary F Feitosa Lihua Wang Jin-Fang Chai Massimiliano Cocca Christian Fuchsberger Mathias Gorski Anselm Hoppmann Katrin Horn Man Li Jonathan Marten Damia Noce Teresa Nutile Sanaz Sedaghat Gardar Sveinbjornsson Bamidele O Tayo Peter J van der Most Yizhe Xu Zhi Yu Lea Gerstner Johan Ärnlöv Stephan J L Bakker Daniela Baptista Mary L Biggs Eric Boerwinkle Hermann Brenner Ralph Burkhardt Robert J Carroll Miao-Li Chee Miao-Ling Chee Mengmeng Chen Ching-Yu Cheng James P Cook Josef Coresh Tanguy Corre John Danesh Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Katalin Dittrich Jasmin Divers Kai-Uwe Eckardt Georg Ehret Karlhans Endlich Janine F Felix Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Ron T Gansevoort Vilmantas Giedraitis Martin Gögele Franziska Grundner-Culemann Daniel F Gudbjartsson Vilmundur Gudnason Pavel Hamet Tamara B Harris Andrew A Hicks Hilma Holm Valencia Hui Xian Foo Shih-Jen Hwang M Arfan Ikram Erik Ingelsson Vincent W V Jaddoe Johanna Jakobsdottir Navya Shilpa Josyula Bettina Jung Mika Kähönen Chiea-Chuen Khor Wieland Kiess Wolfgang Koenig Antje Körner Peter Kovacs Holly Kramer Bernhard K Krämer Florian Kronenberg Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jianjun Liu Markus Loeffler Leo-Pekka Lyytikäinen Anubha Mahajan Joseph C Maranville Deborah Mascalzoni Barbara McMullen Christa Meisinger Thomas Meitinger Kozeta Miliku Dennis O Mook-Kanamori Martina Müller-Nurasyid Josyf C Mychaleckyj Matthias Nauck Kjell Nikus Boting Ning Raymond Noordam Jeffrey O' Connell Isleifur Olafsson Nicholette D Palmer Annette Peters Anna I Podgornaia Belen Ponte Tanja Poulain Peter P Pramstaller Ton J Rabelink Laura M Raffield Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Fernando Rivadeneira Heiko Runz Kathleen A Ryan Charumathi Sabanayagam Kai-Uwe Saum Ben Schöttker Christian M Shaffer Yuan Shi Albert V Smith Konstantin Strauch Michael Stumvoll Benjamin B Sun Silke Szymczak E-Shyong Tai Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Unnur Thorsteinsdottir Anke Tönjes Johanne Tremblay André G Uitterlinden Pim van der Harst Niek Verweij Suzanne Vogelezang Uwe Völker Melanie Waldenberger Chaolong Wang Otis D Wilson Charlene Wong Tien-Yin Wong Qiong Yang Masayuki Yasuda Shreeram Akilesh Murielle Bochud Carsten A Böger Olivier Devuyst Todd L Edwards Kevin Ho Andrew P Morris Afshin Parsa Sarah A Pendergrass Bruce M Psaty Jerome I Rotter Kari Stefansson James G Wilson Katalin Susztak Harold Snieder Iris M Heid Markus Scholz Adam S Butterworth Adriana M Hung Cristian Pattaro Anna Köttgen

Nat Commun 2019 Sep 11;10(1):4130. Epub 2019 Sep 11.

Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41467-019-11576-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739370PMC
September 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

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http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698888PMC
June 2019

Cutting Edge: BCAP Promotes Lupus-like Disease and TLR-Mediated Type I IFN Induction in Plasmacytoid Dendritic Cells.

J Immunol 2019 May 1;202(9):2529-2534. Epub 2019 Apr 1.

Immunology Program, Benaroya Research Institute, Seattle, WA 98109;

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http://dx.doi.org/10.4049/jimmunol.1801267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516743PMC
May 2019

A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis.

Neoplasia 2018 06 7;20(6):610-620. Epub 2018 May 7.

Kidney Research Institute, University of Washington, Box 359606, 325 Ninth Avenue, Seattle, WA 98104; Fred Hutchinson Cancer Research Center / University of Washington Cancer Consortium, 1100 Fairview Ave N, Seattle, WA 98109; Department of Pathology, University of Washington, Box 356100, 1959 NE Pacific Street, Seattle, WA 98195. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14765586173048
Publisher Site
http://dx.doi.org/10.1016/j.neo.2018.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994779PMC
June 2018

B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement.

JCI Insight 2017 11 2;2(21). Epub 2017 Nov 2.

Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1172/jci.insight.81836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752294PMC
November 2017

Cross-Platform DNA Encoding for Single-Cell Imaging of Gene Expression.

Angew Chem Int Ed Engl 2016 07 7;55(31):8975-8. Epub 2016 Jun 7.

Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.

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http://dx.doi.org/10.1002/anie.201603945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036947PMC
July 2016

Chronic Ifosfamide toxicity: kidney pathology and pathophysiology.

Am J Kidney Dis 2014 May 8;63(5):843-50. Epub 2014 Feb 8.

Department of Pathology, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1053/j.ajkd.2013.11.028DOI Listing
May 2014

Combined crystalline podocytopathy and tubulopathy associated with multiple myeloma.

Hum Pathol 2014 Apr 19;45(4):875-9. Epub 2013 Oct 19.

Department of Pathology, University of Washington, Seattle, WA 98195; Pathology and Laboratory Medicine Services, Veterans Administration Puget Sound Health Care System, Seattle, WA 98108.

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http://dx.doi.org/10.1016/j.humpath.2013.10.007DOI Listing
April 2014

Infectious pseudotumors: red herrings in head and neck pathology.

Head Neck Pathol 2012 Mar 20;6(1):58-63. Epub 2012 Mar 20.

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1007/s12105-012-0340-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311936PMC
March 2012

Pseudotumor of the tracheal-laryngeal junction with unusual morphologic features caused by Rhodococcus equi infection.

Head Neck Pathol 2011 Dec 26;5(4):395-400. Epub 2011 Apr 26.

Department of Pathology and Immunology, Barnes-Jewish Hospital, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1007/s12105-011-0259-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210230PMC
December 2011

Expression profiles of podocytes exposed to high glucose reveal new insights into early diabetic glomerulopathy.

Lab Invest 2011 Apr 22;91(4):488-98. Epub 2010 Nov 22.

Renal Division, Department of Internal Medicine, Washington University, School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1038/labinvest.2010.188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068212PMC
April 2011

Podocytes use FcRn to clear IgG from the glomerular basement membrane.

Proc Natl Acad Sci U S A 2008 Jan 15;105(3):967-72. Epub 2008 Jan 15.

Department of Pathology and Immunology, Renal Division, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1073/pnas.0711515105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242706PMC
January 2008

An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells.

J Exp Med 2007 Nov 5;204(12):2889-97. Epub 2007 Nov 5.

Department of Pathology and Immunology, Washington University School of Medicine and Siteman Cancer Center, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1084/jem.20071283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118522PMC
November 2007

Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism.

J Immunol 2007 Oct;179(7):4580-8

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.4049/jimmunol.179.7.4580DOI Listing
October 2007

FcRn: the neonatal Fc receptor comes of age.

Nat Rev Immunol 2007 Sep 17;7(9):715-25. Epub 2007 Aug 17.

The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA.

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http://www.nature.com/articles/nri2155
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http://dx.doi.org/10.1038/nri2155DOI Listing
September 2007

Metal-binding thermodynamics of the histidine-rich sequence from the metal-transport protein IRT1 of Arabidopsis thaliana.

Inorg Chem 2006 Oct;45(21):8500-8

Departments of Chemistry and Biological Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA.

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http://dx.doi.org/10.1021/ic0606431DOI Listing
October 2006