Publications by authors named "Shravan Morla"

11Publications

Skeletal muscle myosin and cardiac myosin attenuate heparin's antithrombin-dependent anticoagulant activity.

J Thromb Haemost 2020 Nov 11. Epub 2020 Nov 11.

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1111/jth.15169DOI Listing
November 2020

Novel blood coagulation molecules: Skeletal muscle myosin and cardiac myosin.

J Thromb Haemost 2020 Sep 13. Epub 2020 Sep 13.

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1111/jth.15097DOI Listing
September 2020

Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8.

Biomolecules 2020 08 9;10(8). Epub 2020 Aug 9.

Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA 23298, USA.

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http://dx.doi.org/10.3390/biom10081166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465109PMC
August 2020

On the Process of Discovering Leads That Target the Heparin-Binding Site of Neutrophil Elastase in the Sputum of Cystic Fibrosis Patients.

J Med Chem 2019 06 28;62(11):5501-5511. Epub 2019 May 28.

Department of Medicinal Chemistry , Virginia Commonwealth University , Richmond , Virginia 23298 , United States.

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http://dx.doi.org/10.1021/acs.jmedchem.9b00379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818412PMC
June 2019

Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation.

Authors:
Shravan Morla

Int J Mol Sci 2019 Apr 22;20(8). Epub 2019 Apr 22.

Department of Medicinal Chemistry, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA 23219, USA.

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http://dx.doi.org/10.3390/ijms20081963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514582PMC
April 2019

Polymeric fluorescent heparin as one-step FRET substrate of human heparanase.

Carbohydr Polym 2019 Feb 28;205:385-391. Epub 2018 Oct 28.

Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA 23219, USA; Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA 23219, USA. Electronic address:

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http://dx.doi.org/10.1016/j.carbpol.2018.10.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245667PMC
February 2019

A Unique Nonsaccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation.

Mol Cancer Ther 2019 01 18;18(1):51-61. Epub 2018 Oct 18.

Division of Hematology and Oncology, Department of Internal Medicine, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-0104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332501PMC
January 2019

Design, synthesis, biological evaluation of substituted benzofurans as DNA gyraseB inhibitors of Mycobacterium tuberculosis.

Bioorg Med Chem 2014 Sep 27;22(17):4924-34. Epub 2014 Jun 27.

Department of Pharmacy, Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Jawaharnagar, Shameerpet, RangaReddy Dist, Hyderabad 500078, India. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2014.06.041DOI Listing
September 2014

Development of novel N-linked aminopiperidine-based mycobacterial DNA gyrase B inhibitors: scaffold hopping from known antibacterial leads.

Int J Antimicrob Agents 2014 Mar 25;43(3):269-78. Epub 2013 Dec 25.

Department of Pharmacy, Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad 500078, Andhra Pradesh, India. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2013.12.006DOI Listing
March 2014