Shozeb Haider

Shozeb Haider

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Shozeb Haider

Publications by authors named "Shozeb Haider"

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Beyond Bone Biology: Lessons from Team Science.

J Orthop Res 2020 Jun 10. Epub 2020 Jun 10.

The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1002/jor.24771DOI Listing
June 2020

Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.

Nucleic Acids Res 2020 May 26. Epub 2020 May 26.

State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.

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http://dx.doi.org/10.1093/nar/gkaa439DOI Listing
May 2020

Synergistic Effect of Chlorogenic Acid and Caffeic Acid with Fosfomycin on Growth Inhibition of a Resistant Strain.

ACS Omega 2020 Apr 23;5(13):7537-7544. Epub 2020 Mar 23.

Department of Chemical Engineering, Villanova University, 800 E Lancaster Avenue, Villanova, Pennsylvania 19085, United States.

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http://dx.doi.org/10.1021/acsomega.0c00352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144146PMC
April 2020

Electrostatic Switching Controls Channel Dynamics of the Sensor Protein VirB10 in Type IV Secretion System.

ACS Omega 2020 Feb 4;5(7):3271-3281. Epub 2020 Feb 4.

Department of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy, WC1N 1AX London, United Kingdom.

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http://dx.doi.org/10.1021/acsomega.9b03313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045316PMC
February 2020

Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5-Inhibitor Complexes.

Mol Cancer Ther 2019 12 5;18(12):2394-2406. Epub 2019 Sep 5.

Université Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS), Grenoble, France.

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http://dx.doi.org/10.1158/1535-7163.MCT-19-0154DOI Listing
December 2019

Discovery of a potent histone deacetylase (HDAC) 3/6 selective dual inhibitor.

Eur J Med Chem 2019 Dec 7;184:111755. Epub 2019 Oct 7.

Department of Pharmacy, National University of Singapore, 18 Science Drive 4, 117543, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.111755DOI Listing
December 2019

Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant.

Biochemistry 2019 11 4;58(45):4480-4493. Epub 2019 Nov 4.

Department of Chemistry , University of Michigan , 930 North University Avenue , Ann Arbor , Michigan 48109 , United States.

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http://dx.doi.org/10.1021/acs.biochem.9b00653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903415PMC
November 2019

Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH Pathway.

ACS Omega 2019 Jul 10;4(7):11960-11972. Epub 2019 Jul 10.

Centre for Biomarker Research, School of Applied Sciences, Department of Pharmacy, School of Applied Sciences, Innovative Physical Organic Solutions (IPOS), Department of Chemical and Biological Sciences, and Department of Chemical Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, U.K.

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http://dx.doi.org/10.1021/acsomega.9b01228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682008PMC
July 2019

Reply to Graham et al.: In silico atomistic coordinates and molecular dynamics simulation trajectories of the glucocerebrosidase-saposin C complex.

Proc Natl Acad Sci U S A 2019 06;116(23):11101-11102

Department of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy, London WC1N 1AX, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1905744116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561302PMC
June 2019

Selective recognition of c-MYC Pu22 G-quadruplex by a fluorescent probe.

Nucleic Acids Res 2019 03;47(5):2190-2204

State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, PR China.

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http://dx.doi.org/10.1093/nar/gkz059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412119PMC
March 2019

Holliday Junctions Formed from Human Telomeric DNA.

J Am Chem Soc 2018 11 30;140(45):15366-15374. Epub 2018 Oct 30.

UCL School of Pharmacy , University College London , London WC1N 1AX , United Kingdom.

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http://dx.doi.org/10.1021/jacs.8b08699DOI Listing
November 2018

Structural Dynamics of Lateral and Diagonal Loops of Human Telomeric G-Quadruplexes in Extended MD Simulations.

J Chem Theory Comput 2018 Oct 28;14(10):5011-5026. Epub 2018 Sep 28.

Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135 , 612 65 Brno , Czech Republic.

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http://pubs.acs.org/doi/10.1021/acs.jctc.8b00543
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http://dx.doi.org/10.1021/acs.jctc.8b00543DOI Listing
October 2018

Carbazole ligands as c-myc G-quadruplex binders.

Int J Biol Macromol 2018 Jul 23;114:479-490. Epub 2018 Mar 23.

Department of Pharmaceutical and Biological Chemistry, School of Pharmacy, University College London, London WC1N 1AX, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S01418130173521
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http://dx.doi.org/10.1016/j.ijbiomac.2018.03.135DOI Listing
July 2018

Boronic acid inhibitors of the class A β-lactamase KPC-2.

Bioorg Med Chem 2018 07 27;26(11):2921-2927. Epub 2018 Apr 27.

UCL School of Pharmacy, 29-39 Brunswick Sq., London WC1N 1AX, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896183023
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http://dx.doi.org/10.1016/j.bmc.2018.04.055DOI Listing
July 2018

Carbazole Derivatives' Binding to c-KIT G-Quadruplex DNA.

Molecules 2018 05 10;23(5). Epub 2018 May 10.

School of Pharmacy, University College London, London WC1N 1AX, UK.

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http://dx.doi.org/10.3390/molecules23051134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099540PMC
May 2018

G-Quadruplexes (GQU).

J Nucleic Acids 2018 30;2018:1079191. Epub 2018 Apr 30.

Department of Chemistry, University of St. Thomas, St. Paul, MN, USA.

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http://dx.doi.org/10.1155/2018/1079191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952435PMC
April 2018

Regioselective glycosylation of novobiocin alters activity.

Carbohydr Res 2017 Nov 22;452:116-121. Epub 2017 Oct 22.

The School of Pharmacy, University College London, 29/39 Brunswick Square, London WC1N 1AX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.carres.2017.10.011DOI Listing
November 2017

Exploring the Dynamics of Propeller Loops in Human Telomeric DNA Quadruplexes Using Atomistic Simulations.

J Chem Theory Comput 2017 Jun 18;13(6):2458-2480. Epub 2017 May 18.

Institute of Biophysics, Academy of Sciences of the Czech Republic , Královopolská 135, 612 65 Brno, Czech Republic.

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http://dx.doi.org/10.1021/acs.jctc.7b00226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514396PMC
June 2017

Folding of guanine quadruplex molecules-funnel-like mechanism or kinetic partitioning? An overview from MD simulation studies.

Biochim Biophys Acta Gen Subj 2017 May 13;1861(5 Pt B):1246-1263. Epub 2016 Dec 13.

Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacky University Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.

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http://dx.doi.org/10.1016/j.bbagen.2016.12.008DOI Listing
May 2017

SET domain-mediated lysine methylation in lower organisms regulates growth and transcription in hosts.

Ann N Y Acad Sci 2016 07 25;1376(1):18-28. Epub 2016 Feb 25.

City University of New York, Medgar Evers College, Brooklyn, New York.

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http://dx.doi.org/10.1111/nyas.13017DOI Listing
July 2016

A novel mutation in HSD11B2 causes apparent mineralocorticoid excess in an Omani kindred.

Ann N Y Acad Sci 2016 07 15;1376(1):65-71. Epub 2016 Aug 15.

Department of Pediatrics and Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1111/nyas.13162DOI Listing
July 2016

Can We Execute Reliable MM-PBSA Free Energy Computations of Relative Stabilities of Different Guanine Quadruplex Folds?

J Phys Chem B 2016 Mar 11;120(11):2899-912. Epub 2016 Mar 11.

Institute of Biophysics, Academy of Sciences of the Czech Republic , Královopolská 135, 612 65 Brno, Czech Republic.

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http://dx.doi.org/10.1021/acs.jpcb.6b01059DOI Listing
March 2016

Structural Insights into the Quadruplex-Duplex 3' Interface Formed from a Telomeric Repeat: A Potential Molecular Target.

J Am Chem Soc 2016 Feb 19;138(4):1226-33. Epub 2016 Jan 19.

UCL School of Pharmacy, University College London , London WC1N 1AX, United Kingdom.

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http://dx.doi.org/10.1021/jacs.5b10492DOI Listing
February 2016

A rare CYP21A2 mutation in a congenital adrenal hyperplasia kindred displaying genotype-phenotype nonconcordance.

Ann N Y Acad Sci 2016 Jan 20;1364:5-10. Epub 2015 Aug 20.

Division of Adrenal Steroid Disorders, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1111/nyas.12864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761329PMC
January 2016

Extended molecular dynamics of a c-kit promoter quadruplex.

Nucleic Acids Res 2015 Oct 5;43(18):8673-93. Epub 2015 Aug 5.

Central European Institute of Technology (CEITEC), Masaryk University, Campus Bohunice, Kamenice 5, 625 00 Brno, Czech Republic Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 612 65 Brno, Czech Republic

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http://nar.oxfordjournals.org/content/early/2015/08/04/nar.g
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http://discovery.ucl.ac.uk/1470026/9/nar-00989-f-2015-File01
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gkv785
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http://dx.doi.org/10.1093/nar/gkv785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605300PMC
October 2015

Dominant Driving Forces in Human Telomere Quadruplex Binding-Induced Structural Alterations.

Biophys J 2015 Jun;108(12):2903-11

Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2015.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472043PMC
June 2015

Bisphosphonates inactivate human EGFRs to exert antitumor actions.

Proc Natl Acad Sci U S A 2014 Dec 1;111(50):17989-94. Epub 2014 Dec 1.

Departments of Medicine, Pediatrics, and Chemical and Structural Biology, and the Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029;

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http://dx.doi.org/10.1073/pnas.1421410111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273397PMC
December 2014

N-substituted piperazinopyridylsteroid derivatives as abiraterone analogues inhibit growth and induce pro-apoptosis in human hormone-independent prostate cancer cell lines.

Chem Biol Drug Des 2013 Nov;82(5):620-9

Université de Caen/Basse-Normandie, Esplanade de la Paix, 14032, Caen cedex, France; UFR des Sciences Pharmaceutiques, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), CNRS INC3M - SFR ICORE 146, Bd Becquerel, F-14032, Caen cedex, France.

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http://dx.doi.org/10.1111/cbdd.12195DOI Listing
November 2013

Conformational dynamics of the human propeller telomeric DNA quadruplex on a microsecond time scale.

Nucleic Acids Res 2013 Feb 4;41(4):2723-35. Epub 2013 Jan 4.

Centre for Cancer Research and Cell Biology, Queen's University of Belfast, Belfast BT9 7BL, UK.

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http://dx.doi.org/10.1093/nar/gks1331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575793PMC
February 2013

Structure-phenotype correlations of human CYP21A2 mutations in congenital adrenal hyperplasia.

Proc Natl Acad Sci U S A 2013 Feb 28;110(7):2605-10. Epub 2013 Jan 28.

Centre of Cancer Research and Cell Biology, Queen's University of Belfast, Belfast BT9 7BL, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1221133110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574933PMC
February 2013

Molecular dynamics of HIV1-integrase in complex with 93del - a structural perspective on the mechanism of inhibition.

J Biomol Struct Dyn 2012 ;29(5):863-77

Centre for Cancer Research and Cell Biology, Queen's University of Belfast, 97 Lisburn Road, BT9 7BL, Belfast, UK.

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http://dx.doi.org/10.1080/07391102.2012.10507418DOI Listing
October 2012

New anti-HIV aptamers based on tetra-end-linked DNA G-quadruplexes: effect of the base sequence on anti-HIV activity.

Chem Commun (Camb) 2012 Oct;48(76):9516-8

Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, Via D. Montesano 49, I-80131 Napoli, Italy.

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http://dx.doi.org/10.1039/c2cc34399aDOI Listing
October 2012

Molecular dynamics studies of the STAT3 homodimer:DNA complex: relationships between STAT3 mutations and protein-DNA recognition.

J Chem Inf Model 2012 May 3;52(5):1179-92. Epub 2012 May 3.

CRUK Biomolecular Structure Group, UCL School of Pharmacy, University College London, WC1N 1AX London, UK.

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http://dx.doi.org/10.1021/ci200625qDOI Listing
May 2012

A structural analysis of G-quadruplex/ligand interactions.

Biochimie 2011 Aug 26;93(8):1239-51. Epub 2011 May 26.

Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, UK.

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http://dx.doi.org/10.1016/j.biochi.2011.05.012DOI Listing
August 2011

Surface area accessibility and the preferred topology of telomeric DNA quadruplex-ligand complexes.

Biochimie 2011 Aug 30;93(8):1275-9. Epub 2011 May 30.

CRUK Biomolecular Structure Group, The School of Pharmacy, University of London, London, UK.

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http://dx.doi.org/10.1016/j.biochi.2011.05.014DOI Listing
August 2011

On the function of the internal cavity of histone deacetylase protein 8: R37 is a crucial residue for catalysis.

Bioorg Med Chem Lett 2011 Apr 2;21(7):2129-32. Epub 2011 Feb 2.

Centre for Cancer Research and Cell Biology, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X110016
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http://dx.doi.org/10.1016/j.bmcl.2011.01.128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286521PMC
April 2011

Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.

Chem Commun (Camb) 2010 Dec 25;46(47):8971-3. Epub 2010 Oct 25.

Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, Via D. Montesano 49, I-80131 Napoli, Italy.

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http://xlink.rsc.org/?DOI=c0cc02866e
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http://dx.doi.org/10.1039/c0cc02866eDOI Listing
December 2010

A novel small-molecule inhibitor of IL-6 signalling.

Bioorg Med Chem Lett 2010 Dec 29;20(23):7029-32. Epub 2010 Sep 29.

Cancer Research UK Protein, The School of Pharmacy, University of London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.bmcl.2010.09.117DOI Listing
December 2010

Structure-based design of selective high-affinity telomeric quadruplex-binding ligands.

Chem Commun (Camb) 2010 Dec 29;46(48):9116-8. Epub 2010 Oct 29.

CRUK Biomolecular Structure Group, The School of Pharmacy, University of London, London WC1N 1AX, UK.

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http://dx.doi.org/10.1039/c0cc02917cDOI Listing
December 2010

A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex.

Nucleic Acids Res 2010 Sep 22;38(16):5569-80. Epub 2010 Apr 22.

Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, UK.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkq259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938214PMC
September 2010

Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.

J Am Chem Soc 2010 Sep;132(35):12263-72

CR-UK Biomolecular Structure Group, The School of Pharmacy, University of London, London WC1N 1AX, UK.

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http://dx.doi.org/10.1021/ja1003944DOI Listing
September 2010

Bis-guanylhydrazone diimidazo[1,2-a:1,2-c]pyrimidine as a novel and specific G-quadruplex binding motif.

Chem Commun (Camb) 2010 Aug 28;46(31):5680-2. Epub 2010 Jun 28.

Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London, WC1N 1AX, UK.

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http://dx.doi.org/10.1039/c0cc00020eDOI Listing
August 2010

Molecular modeling on inhibitor complexes and active-site dynamics of cytochrome P450 C17, a target for prostate cancer therapy.

J Mol Biol 2010 Jul 2;400(5):1078-98. Epub 2010 Jun 2.

CRUK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S002228361000587
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http://dx.doi.org/10.1016/j.jmb.2010.05.069DOI Listing
July 2010

A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands.

Org Biomol Chem 2010 Jun 25;8(13):2926-30. Epub 2010 May 25.

The School of Chemistry, University of Nottingham, University Park, Nottingham, UK NG7 2RD.

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http://dx.doi.org/10.1039/c005055eDOI Listing
June 2010

Molecular modeling and simulation of G-quadruplexes and quadruplex-ligand complexes.

Methods Mol Biol 2010 ;608:17-37

The Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London, UK.

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http://dx.doi.org/10.1007/978-1-59745-363-9_2DOI Listing
February 2010

Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes.

Chem Commun (Camb) 2009 Dec 13(48):7482-4. Epub 2009 Nov 13.

Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London, UK WC1N 1AX.

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http://dx.doi.org/10.1039/b901889aDOI Listing
December 2009

Biaryl polyamides as a new class of DNA quadruplex-binding ligands.

Chem Commun (Camb) 2009 Jul 5(27):4097-9. Epub 2009 Jun 5.

Gene Targeted Drug Design Research Group, The School of Pharmacy, University of London, 29/39 Brunswick Square, London, UK WC1N 1AX.

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http://dx.doi.org/10.1039/b902359cDOI Listing
July 2009

A molecular model for drug binding to tandem repeats of telomeric G-quadruplexes.

Biochem Soc Trans 2009 Jun;37(Pt 3):583-8

CRUK Biomolecular Structure Group, The School of Pharmacy, University of London, London, UK.

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http://dx.doi.org/10.1042/BST0370583DOI Listing
June 2009

Ion channel gates: comparative analysis of energy barriers.

Eur Biophys J 2009 Apr 16;38(4):347-54. Epub 2008 Oct 16.

Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.

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http://dx.doi.org/10.1007/s00249-008-0377-xDOI Listing
April 2009

Molecular dynamics and principal components analysis of human telomeric quadruplex multimers.

Biophys J 2008 Jul 28;95(1):296-311. Epub 2008 Mar 28.

Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London, United Kingdom.

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http://dx.doi.org/10.1529/biophysj.107.120501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426654PMC
July 2008

Targeting telomerase and telomeres: a click chemistry approach towards highly selective G-quadruplex ligands.

Mol Biosyst 2008 Jun 8;4(6):629-42. Epub 2008 Apr 8.

CRUK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London, UK.

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http://dx.doi.org/10.1039/b801822gDOI Listing
June 2008

Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands.

Bioorg Med Chem Lett 2008 Mar 18;18(5):1668-73. Epub 2008 Jan 18.

CRUK Biomolecular Structure Group, The School of Pharmacy, University of London, 29/39 Brunswick Square, London WC1N 1AX, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S0960894X0800065
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http://dx.doi.org/10.1016/j.bmcl.2008.01.050DOI Listing
March 2008

Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter.

Nucleic Acids Res 2007 24;35(17):5799-808. Epub 2007 Aug 24.

Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, UK.

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http://dx.doi.org/10.1093/nar/gkm609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034477PMC
November 2007

Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis.

EMBO J 2007 Aug 2;26(16):3749-59. Epub 2007 Aug 2.

Department of Biochemistry, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/sj.emboj.7601809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952224PMC
August 2007

Simulations of a protein translocation pore: SecY.

Biochemistry 2006 Oct;45(43):13018-24

Department of Biochemistry, University of Oxford, UK.

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http://pubs.acs.org/doi/abs/10.1021/bi061013d
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http://dx.doi.org/10.1021/bi061013dDOI Listing
October 2006

Functional characterisation of missense variations in the Kir4.1 potassium channel (KCNJ10) associated with seizure susceptibility.

Brain Res Mol Brain Res 2005 Sep;139(1):178-83

Oxford Centre for Gene Function, University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK.

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http://dx.doi.org/10.1016/j.molbrainres.2005.05.003DOI Listing
September 2005

Focus on Kir6.2: a key component of the ATP-sensitive potassium channel.

J Mol Cell Cardiol 2005 Jun;38(6):927-36

Department of Biochemistry, University of Oxford, UK.

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http://dx.doi.org/10.1016/j.yjmcc.2005.01.007DOI Listing
June 2005

Molecular dynamics simulation approaches to K channels: conformational flexibility and physiological function.

IEEE Trans Nanobioscience 2005 Mar;4(1):112-20

Department of Biochemistry, University of Oxford, Oxford OX 3QU, United Kingdom.

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http://dx.doi.org/10.1109/tnb.2004.842473DOI Listing
March 2005

Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding.

Bioorg Med Chem Lett 2004 Dec;14(23):5845-9

Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, UK.

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http://dx.doi.org/10.1016/j.bmcl.2004.09.037DOI Listing
December 2004

Ion channel structures: a review of recent progress.

Curr Opin Drug Discov Devel 2003 Sep;6(5):611-9

University of Oxford, Laboratory of Molecular Biophysics, Department of Biochemistry, South Parks Road, Oxford, OX1 3QU, UK.

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September 2003

Identification of residues contributing to the ATP binding site of Kir6.2.

EMBO J 2003 Jun;22(12):2903-12

University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK.

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http://dx.doi.org/10.1093/emboj/cdg282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC162134PMC
June 2003

Structure of a G-quadruplex-ligand complex.

J Mol Biol 2003 Feb;326(1):117-25

Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX, London, UK.

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http://dx.doi.org/10.1016/s0022-2836(02)01354-2DOI Listing
February 2003

Crystal structure of the potassium form of an Oxytricha nova G-quadruplex.

J Mol Biol 2002 Jul;320(2):189-200

The Cancer Research UK Biomolecular Structure Unit, Chester Beatty Laboratories, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360200428
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http://dx.doi.org/10.1016/S0022-2836(02)00428-XDOI Listing
July 2002