Show-Li Chen

Show-Li Chen

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Show-Li Chen

Show-Li Chen

Publications by authors named "Show-Li Chen"

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Deficiency of nuclear receptor interaction protein leads to cardiomyopathy by disrupting sarcomere structure and mitochondrial respiration.

J Mol Cell Cardiol 2019 12 17;137:9-24. Epub 2019 Oct 17.

Department and Graduate Institute of Microbiology, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.09.009DOI Listing
December 2019

The Psoriasis Therapeutic Potential of a Novel Short Laminin Peptide C16.

Int J Mol Sci 2019 Jun 27;20(13). Epub 2019 Jun 27.

Department of Medical Research, Mackay Memorial Hospital, No. 45, Minsheng Rd., Tamsui District, New Taipei City 25160, Taiwan.

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http://dx.doi.org/10.3390/ijms20133144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651782PMC
June 2019

PEDF-derived peptide promotes tendon regeneration through its mitogenic effect on tendon stem/progenitor cells.

Stem Cell Res Ther 2019 01 3;10(1). Epub 2019 Jan 3.

Department of Medical Research, Mackay Memorial Hospital, No. 45, Minsheng Rd., Tamsui District, New Taipei City, 25160, Taiwan.

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http://dx.doi.org/10.1186/s13287-018-1110-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318926PMC
January 2019

Muscle-restricted nuclear receptor interaction protein knockout causes motor neuron degeneration through down-regulation of myogenin at the neuromuscular junction.

J Cachexia Sarcopenia Muscle 2018 08 2;9(4):771-785. Epub 2018 Apr 2.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, 7F, No. 1, Sec. 1, Jen-Ai Rd., Taipei, 100, Taiwan.

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http://dx.doi.org/10.1002/jcsm.12299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104115PMC
August 2018

NRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4A-DDB1 E3 ligase complex in prostate cancer.

Oncotarget 2017 Mar;8(13):21501-21515

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.

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http://dx.doi.org/10.18632/oncotarget.15308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400601PMC
March 2017

Pigment epithelium-derived factor (PEDF) peptide promotes the expansion of hepatic stem/progenitor cells via ERK and STAT3-dependent signaling.

Am J Transl Res 2017 15;9(3):1114-1126. Epub 2017 Mar 15.

Department of Medical Research, Ophthalmology, Mackay Memorial Hospital No. 92 Zhongshan North Road, Taipei, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376003PMC
March 2017

Pigment Epithelial-Derived Factor Peptide Regenerated Limbus Serves as Regeneration Source for Limbal Regeneration in Rabbit Limbal Deficiency.

Invest Ophthalmol Vis Sci 2016 05;57(6):2629-36

Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan 3Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1167/iovs.15-17171DOI Listing
May 2016

Phosphorylation of HPV-16 E2 at serine 243 enables binding to Brd4 and mitotic chromosomes.

PLoS One 2014 23;9(10):e110882. Epub 2014 Oct 23.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110882PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207782PMC
February 2016

NRIP is newly identified as a Z-disc protein, activating calmodulin signaling for skeletal muscle contraction and regeneration.

J Cell Sci 2015 Nov 1;128(22):4196-209. Epub 2015 Oct 1.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei 100, Taiwan

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http://dx.doi.org/10.1242/jcs.174441DOI Listing
November 2015

PEDF-derived peptide promotes skeletal muscle regeneration through its mitogenic effect on muscle progenitor cells.

Am J Physiol Cell Physiol 2015 Aug 3;309(3):C159-68. Epub 2015 Jun 3.

Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan;

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http://dx.doi.org/10.1152/ajpcell.00344.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525084PMC
August 2015

Pigment Epithelial-Derived Factor Peptide Facilitates the Regeneration of a Functional Limbus in Rabbit Partial Limbal Deficiency.

Invest Ophthalmol Vis Sci 2015 Apr;56(4):2126-34

Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan 3Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1167/iovs.14-15983DOI Listing
April 2015

PEDF promotes self-renewal of limbal stem cell and accelerates corneal epithelial wound healing.

Stem Cells 2013 Sep;31(9):1775-84

Department of Medical Research, Mackay Memorial Hospital Taipei, Taiwan, Republic of China.

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http://dx.doi.org/10.1002/stem.1393DOI Listing
September 2013

BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing.

RNA 2013 Feb 17;19(2):208-18. Epub 2012 Dec 17.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.

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http://dx.doi.org/10.1261/rna.034835.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543084PMC
February 2013

DDB2 is a novel AR interacting protein and mediates AR ubiquitination/degradation.

Int J Biochem Cell Biol 2012 Nov 28;44(11):1952-61. Epub 2012 Jul 28.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.

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http://dx.doi.org/10.1016/j.biocel.2012.07.023DOI Listing
November 2012

NRIP enhances HPV gene expression via interaction with either GR or E2.

Virology 2012 Feb 15;423(1):38-48. Epub 2011 Dec 15.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.

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http://linkinghub.elsevier.com/retrieve/pii/S004268221100544
Publisher Site
http://dx.doi.org/10.1016/j.virol.2011.11.015DOI Listing
February 2012

NRIP, a novel calmodulin binding protein, activates calcineurin to dephosphorylate human papillomavirus E2 protein.

J Virol 2011 Jul 4;85(13):6750-63. Epub 2011 May 4.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, 7F, No1, Sec. 1, Jen-Ai Rd., Taipei, Taiwan.

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http://dx.doi.org/10.1128/JVI.02453-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126500PMC
July 2011

Pigment epithelium-derived factor is an intrinsic antifibrosis factor targeting hepatic stellate cells.

Am J Pathol 2010 Oct 13;177(4):1798-811. Epub 2010 Aug 13.

Department of Medical Research, Mackay Memorial Hospital, School of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.2353/ajpath.2010.091085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947276PMC
October 2010

Retinal protection from acute glaucoma-induced ischemia-reperfusion injury through pharmacologic induction of heme oxygenase-1.

Invest Ophthalmol Vis Sci 2010 Sep 31;51(9):4798-808. Epub 2010 Mar 31.

Department of Ophthalmology, Chang Gung Memorial Hospital, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.

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http://dx.doi.org/10.1167/iovs.09-4086DOI Listing
September 2010

Pigment epithelium-derived factor induces interleukin-10 expression in human macrophages by induction of PPAR gamma.

Life Sci 2010 Jul 27;87(1-2):26-35. Epub 2010 May 27.

Centers for Disease Control, Taiwan.

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http://dx.doi.org/10.1016/j.lfs.2010.05.007DOI Listing
July 2010

Breast cancer amplified sequence 2, a novel negative regulator of the p53 tumor suppressor.

Cancer Res 2009 Dec 10;69(23):8877-85. Epub 2009 Nov 10.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2023DOI Listing
December 2009

Suppression of experimental uveitis by a recombinant adeno-associated virus vector encoding interleukin-1 receptor antagonist.

Mol Vis 2009 Aug 8;15:1542-52. Epub 2009 Aug 8.

Department of Ophthalmology, Tri-Service General Hospital, Taipei, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723168PMC
August 2009

Cytosolic phospholipase A2-{alpha} is an early apoptotic activator in PEDF-induced endothelial cell apoptosis.

Am J Physiol Cell Physiol 2009 Feb 17;296(2):C273-84. Epub 2008 Dec 17.

Dept. of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1152/ajpcell.00432.2008DOI Listing
February 2009

Viral delivery of heme oxygenase-1 attenuates photoreceptor apoptosis in an experimental model of retinal detachment.

Vision Res 2008 Oct 7;48(22):2394-402. Epub 2008 Sep 7.

Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.visres.2008.07.017DOI Listing
October 2008

Nuclear receptor interaction protein, a coactivator of androgen receptors (AR), is regulated by AR and Sp1 to feed forward and activate its own gene expression through AR protein stability.

Nucleic Acids Res 2008 Jan 5;36(1):51-66. Epub 2007 Nov 5.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1093/nar/gkm942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248731PMC
January 2008

Troglitazone suppresses transforming growth factor beta-mediated fibrogenesis in retinal pigment epithelial cells.

Mol Vis 2008 Jan 18;14:95-104. Epub 2008 Jan 18.

Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254970PMC
January 2008

Photoreceptor protection against light damage by AAV-mediated overexpression of heme oxygenase-1.

Invest Ophthalmol Vis Sci 2007 Dec;48(12):5699-707

Department of Ophthalmology, Chang Gung Memorial Hospital [corrected] Taoyuan, Taiwan.

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http://dx.doi.org/10.1167/iovs.07-0340DOI Listing
December 2007

Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line.

BMC Cancer 2007 Nov 20;7:216. Epub 2007 Nov 20.

Mackay Medicine, Nursing and Management College, Taipei, Taiwan.

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http://dx.doi.org/10.1186/1471-2407-7-216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233635PMC
November 2007

Cytotoxic T-lymphocyte responses to human papillomavirus type 16 E5 and E7 proteins and HLA-A*0201-restricted T-cell peptides in cervical cancer patients.

J Virol 2007 Mar 3;81(6):2869-79. Epub 2007 Jan 3.

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, 7F, No. 1 Sec. 1 Jen-Ai Rd., Taipei, Taiwan.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.02256-06
Publisher Site
http://dx.doi.org/10.1128/JVI.02256-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865983PMC
March 2007

Reduction of experimental diabetic vascular leakage by delivery of angiostatin with a recombinant adeno-associated virus vector.

Mol Vis 2007 Jan 31;13:133-41. Epub 2007 Jan 31.

Institute of Clinical Medicine, National Yang-Ming University, Taipei and Su-Ao Veterans Hospital, I-Lan, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533034PMC
January 2007

Gene therapy of focal cerebral ischemia using defective recombinant adeno-associated virus vectors.

Front Biosci 2006 Sep 1;11:2061-70. Epub 2006 Sep 1.

Department of Neurosurgery, Tri-Service General Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.2741/1948DOI Listing
September 2006

Pigment epithelium-derived factor protects retinal pigment epithelium from oxidant-mediated barrier dysfunction.

Biochem Biophys Res Commun 2006 Apr 8;342(2):372-8. Epub 2006 Feb 8.

Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.bbrc.2006.01.164DOI Listing
April 2006

Long-term safety of GDNF gene delivery in the retina.

Curr Eye Res 2005 Aug;30(8):715-22

Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

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http://dx.doi.org/10.1080/02713680591005922DOI Listing
August 2005

Recombinant adeno-associated virus vector expressing angiostatin inhibits preretinal neovascularization in adult rats.

Ophthalmic Res 2005 Jan-Feb;37(1):50-6. Epub 2005 Jan 5.

Department of Ophthalmology, Chang-Gung Memorial Hospital, Taoyuan, Taiwan.

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http://dx.doi.org/10.1159/000083040DOI Listing
May 2005

NRIP, a novel nuclear receptor interaction protein, enhances the transcriptional activity of nuclear receptors.

J Biol Chem 2005 May 21;280(20):20000-9. Epub 2005 Mar 21.

Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.

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http://dx.doi.org/10.1074/jbc.M412169200DOI Listing
May 2005

Co-vaccination with adeno-associated virus vectors encoding human papillomavirus 16 L1 proteins and adenovirus encoding murine GM-CSF can elicit strong and prolonged neutralizing antibody.

Int J Cancer 2005 Jan;113(1):93-100

Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, Republic of China.

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http://dx.doi.org/10.1002/ijc.20530DOI Listing
January 2005

Cytotoxic-T-lymphocyte human papillomavirus type 16 E5 peptide with CpG-oligodeoxynucleotide can eliminate tumor growth in C57BL/6 mice.

J Virol 2004 Feb;78(3):1333-43

Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, Republic of China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC321407PMC
http://dx.doi.org/10.1128/jvi.78.3.1333-1343.2004DOI Listing
February 2004

GDNF gene therapy attenuates retinal ischemic injuries in rats.

Mol Vis 2004 Feb 10;10:93-102. Epub 2004 Feb 10.

Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

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February 2004

Gene treatment of cerebral stroke by rAAV vector delivering IL-1ra in a rat model.

Neuroreport 2003 May;14(6):803-7

Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, Republic of China.

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http://dx.doi.org/10.1097/00001756-200305060-00005DOI Listing
May 2003

Oral vaccination with recombinant Listeria monocytogenes expressing human papillomavirus type 16 E7 can cause tumor growth in mice to regress.

Int J Cancer 2002 Dec;102(6):629-37

Department of Microbiology & Immunology, National Defense Medical Center, Taipei, Taiwan, Republic of China.

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http://dx.doi.org/10.1002/ijc.10759DOI Listing
December 2002

Gene therapy for detached retina by adeno-associated virus vector expressing glial cell line-derived neurotrophic factor.

Invest Ophthalmol Vis Sci 2002 Nov;43(11):3480-8

Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

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November 2002

Recombinant adenovirus encoding H-ras ribozyme induces apoptosis in laryngeal cancer cells through caspase- and mitochondria-dependent pathways.

Biochem Biophys Res Commun 2002 Nov;298(5):805-14

Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, ROC.

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http://dx.doi.org/10.1016/s0006-291x(02)02574-3DOI Listing
November 2002

Gene therapy for treatment of cerebral ischemia using defective recombinant adeno-associated virus vectors.

Methods 2002 Oct;28(2):253-8

Department of Neurosurgery, Tri-Service General Hospital, Taipei, Taiwan, ROC.

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http://dx.doi.org/10.1016/s1046-2023(02)00230-xDOI Listing
October 2002

Inducible adeno-associated virus vector-delivered transgene expression in corneal endothelium.

Invest Ophthalmol Vis Sci 2002 Mar;43(3):751-7

The Graduate Institute of Medical Science, National Defense Medical Center, Taipei, Taiwan.

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March 2002